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Author Giuseppe Mancia

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Highlights of the August issue.

Giuseppe Mancia,

J. Hypertens. (Journal of hypertension)
[2019, 37(8):1539-1540]

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Resistant Hypertension Management: Comparison of the 2017 American and 2018 European High Blood Pressure Guidelines.

Guido Grassi, David A Calhoun, Giuseppe Mancia, Robert M Carey,

PURPOSE OF REVIEW:To compare European and American guidelines for the diagnosis, evaluation, and management of resistant hypertension. RECENT FINDINGS:Resistant hypertension is defined as high blood pressure that remains above goal with the use of 3 or more antihypertensive agents, commonly a renin-angiotensin blocker (either an angiotensin-converting enzyme inhibitor or an ... Read more >>

Curr. Hypertens. Rep. (Current hypertension reports)
[2019, 21(9):67]

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The relationship between eGFR slope and subsequent risk of vascular outcomes and all-cause mortality in type 2 diabetes: the ADVANCE-ON study.

Megumi Oshima, Min Jun, Toshiaki Ohkuma, Tadashi Toyama, Takashi Wada, Mark E Cooper, Samy Hadjadj, Pavel Hamet, Stephen Harrap, Giuseppe Mancia, Michel Marre, Bryan Williams, John Chalmers, Mark Woodward, Vlado Perkovic, ,

AIMS/HYPOTHESIS:Some studies have reported that annual change in eGFR (eGFR slope) is associated with the future risk of end-stage kidney disease, cardiovascular disease and death in general or chronic kidney disease cohorts. However, the benefits of using eGFR slopes for prediction of major clinical outcomes in diabetes are unclear. METHODS:We ... Read more >>

Diabetologia (Diabetologia)
[2019, :]

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High-normal blood pressure and abnormal left ventricular geometric patterns: a meta-analysis.

Cesare Cuspidi, Carla Sala, Marijana Tadic, Elisa Gherbesi, Rita Facchetti, Guido Grassi, Giuseppe Mancia,

AIM:The association between prehypertension (pre-HTN) and abnormal left ventricular (LV) geometric patterns is unclear. We performed a meta-analysis of echocardiographic studies aimed to provide a new piece of information on LV geometric alterations in untreated pre-HTN individuals. DESIGN:Studies were identified by crossing the following search terms: 'prehypertension,' 'high normal blood ... Read more >>

J. Hypertens. (Journal of hypertension)
[2019, 37(7):1312-1319]

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Response to: Myocardial fibrosis and arrhythmogenesis in elite athletes.

Cesare Cuspidi, Marijana Tadic, Carla Sala, Elisa Gherbesi, Guido Grassi, Giuseppe Mancia,

Clin Cardiol (Clinical cardiology)
[2019, :]

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Highlights of the July issue.

Giuseppe Mancia,

J. Hypertens. (Journal of hypertension)
[2019, 37(7):1309-1311]

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Sympathetic Neural Overdrive in the Obese and Overweight State.

Guido Grassi, Annalisa Biffi, Gino Seravalle, Fosca Quarti Trevano, Raffaella Dell'Oro, Giovanni Corrao, Giuseppe Mancia,

Nerve traffic recordings (muscle sympathetic nerve traffic [MSNA]) have shown that sympathetic activation may occur in obesity. However, the small sample size of the available studies, presence of comorbidities, heterogeneity of the subjects examined represented major weaknesses not allowing to draw definite conclusions. This is the case for the overweight ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2019, 74(2):349-358]

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Current perspective on the use of calcium channel blockers to treat hypertensive patients: the role of lercanidipine.

Giuseppe Mancia, Kostantinos Tsioufis,

The symposium 'Current perspective on the use of calcium channel blockers in the treatment of hypertensive patients', held in Stresa (Italy) on 28th and 29th June 2018 with the participation of the main experts in the field of hypertension from all over the world, reviewed the role of calcium channel ... Read more >>

Future Cardiol (Future cardiology)
[2019, :]

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Highlights of the June issue.

Giuseppe Mancia,

J. Hypertens. (Journal of hypertension)
[2019, 37(6):1099-1101]

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Hypertension in aortic stenosis: relationship with revealed symptoms and functional measures on treadmill exercise.

Sahrai Saeed, Giuseppe Mancia, Ronak Rajani, Denise Parkin, John B Chambers,

BACKGROUND:The impact of hypertension on symptoms and functional capacity during exercise treadmill test (ETT) in apparently asymptomatic patients with aortic stenosis is poorly understood. METHODS:A total of 314 patients (age 65 ± 12 years, 68% men) with moderate or severe asymptomatic aortic stenosis underwent baseline echocardiography and ETT. Hypertension was defined as ... Read more >>

J. Hypertens. (Journal of hypertension)
[2019, :]

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Effects of Blood Pressure Lowering on Clinical Outcomes According to Baseline Blood Pressure and Cardiovascular Risk in Patients With Type 2 Diabetes Mellitus.

Faisal Rahman, John W McEvoy, Toshiaki Ohkuma, Michel Marre, Pavel Hamet, Stephen Harrap, Giuseppe Mancia, Anthony Rodgers, Elizabeth Selvin, Bryan Williams, Paul Muntner, John Chalmers, Mark Woodward,

The optimal blood pressure (BP) goal in patients with diabetes mellitus remains controversial. We examined whether benefits and risks of intensified antihypertensive therapy in diabetes mellitus are influenced by either baseline BP or cardiovascular disease (CVD) risk. We studied 10 948 people with diabetes mellitus, at moderate-to-high risk, in the ADVANCE ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2019, 73(6):1291-1299]

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Incident Left Ventricular Hypertrophy in Masked Hypertension.

Cesare Cuspidi, Rita Facchetti, Fosca Quarti-Trevano, Carla Sala, Marijana Tadic, Guido Grassi, Giuseppe Mancia,

In the PAMELA study (Pressioni Arteriose Monitorate e Loro Associazioni), clinical variables, an echocardiogram, as well as office and ambulatory blood pressure (ABP) were simultaneously measured at baseline and after a 10-year follow-up. The study design allowed us to assess the value of masked hypertension (MH) as a predictor of ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2019, 74(1):56-62]

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Extreme dipping: is the cardiovascular risk increased? An unsolved issue.

Cesare Cuspidi, Marijana Tadic, Carla Sala, Elisa Gherbesi, Guido Grassi, Giuseppe Mancia,

: Extreme dipping [i.e. a marked blood pressure (BP) fall during night-time period] is an alteration of circadian BP rhythm frequently observed in the setting of systemic hypertension as well as in the general population. Some reports have suggested that cardiovascular prognosis in extreme dippers is similar as in dippers, ... Read more >>

J. Hypertens. (Journal of hypertension)
[2019, :]

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Closed-Loop Cardiovascular Interactions and the Baroreflex Cardiac Arm: Modulations Over the 24 h and the Effect of Hypertension.

Gianfranco Parati, Paolo Castiglioni, Andrea Faini, Marco Di Rienzo, Giuseppe Mancia, Riccardo Barbieri, J Philip Saul,

Closed-loop models of the interactions between blood pressure (BP) and heart rate variations allow for estimation of baroreflex sensitivity (feedback effects of BP changes on heart rate) while also considering the feedforward effects of heart rate on BP. Our study is aimed at comparing modulations of feedback and feedforward couplings ... Read more >>

Front Physiol (Frontiers in physiology)
[2019, 10:477]

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Extreme Dipping : Always means Nocturnal Hypotension ?

Cesare Cuspidi, Giovanni Caffi, Raffaella Dell'Oro, Marijana Tadic, Carla Sala, Guido Grassi, Giuseppe Mancia,

AIM:Although nocturnal hypotension is considered the key factor responsible for the increased cardiovascular risk associated with the extreme dipping (ED) pattern no information is available on its prevalence in this setting. Therefore, we have assessed this topic in a cohort of patients referred to a single out-patient hypertension center. METHODS:A ... Read more >>

Am. J. Hypertens. (American journal of hypertension)
[2019, :]

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Highlights of the May issue.

Giuseppe Mancia,

J. Hypertens. (Journal of hypertension)
[2019, 37(5):863-864]

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Response to 'Comment on 2018 ESC/ESH Guidelines for the management of arterial hypertension'.

Antonio Coca Payeras, Bryan Williams, Giuseppe Mancia,

Eur. Heart J. (European heart journal)
[2019, :]

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Sympathetic neural overdrive in congestive heart failure and its correlates: systematic reviews and meta-analysis.

Guido Grassi, Graziella D'Arrigo, Anna Pisano, Davide Bolignano, Francesca Mallamaci, Raffaella Dell'Oro, Fosca Quarti-Trevano, Gino Seravalle, Giuseppe Mancia, Carmine Zoccali,

BACKGROUND AND OBJECTIVES:Sympathetic neural activation occurs in congestive heart failure (CHF). However, the small sample size of the microneurographic studies, heterogeneity of the patients examined, presence of comorbidities as well as confounders (including treatment) represented major weaknesses not allowing to identify the major features of the phoenomenon, particularly in mild ... Read more >>

J. Hypertens. (Journal of hypertension)
[2019, :]

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Left atrial volume in elite athletes: A meta-analysis of echocardiographic studies.

Cesare Cuspidi, Carla Sala, Marijana Tadic, Giovanni Baccanelli, Elisa Gherbesi, Guido Grassi, Giuseppe Mancia,

AIM:Information on left atrium (LA) enlargement, as assessed by LA volume (LAV) instead of LA diameter, in the athletic population is scanty. To expand current knowledge on this issue, we performed an updated meta-analysis of echocardiographic studies. DESIGN:The Ovid MEDLINE, PubMed, and Cochrane CENTRAL databases were searched for English language ... Read more >>

Scand J Med Sci Sports (Scandinavian journal of medicine & science in sports)
[2019, 29(7):922-932]

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Cardiovascular outcomes and achieved blood pressure in patients with and without diabetes at high cardiovascular risk.

Michael Böhm, Helmut Schumacher, Koon K Teo, Eva M Lonn, Felix Mahfoud, Johannes F E Mann, Giuseppe Mancia, Josep Redon, Roland E Schmieder, Nikolaus Marx, Karen Sliwa, Michael A Weber, Bryan Williams, Salim Yusuf,

AIMS:Studies have shown a non-linear relationship between systolic blood pressure (SBP) and diastolic blood pressure (DBP) and outcomes, with increased risk observed at both low and high blood pressure (BP) levels. We hypothesized that the BP-risk association is different in individuals with and without diabetes at high cardiovascular risk. METHODS ... Read more >>

Eur. Heart J. (European heart journal)
[2019, :]

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Serum uric acid and resistance to antihypertensive treatment: data from the European Lacidipine Study on Atherosclerosis.

Michele Bombelli, Mario Macchiarulo, Rita Facchetti, Davide Maggiolini, Cesare Cuspidi, Gianfranco Parati, Giuseppe Mancia, Guido Grassi,

AIM:Whether increased serum uric acid (SUA) favours resistance to antihypertensive drugs is not clear. METHODS:The European Lacidipine Study on Atherosclerosis (ELSA) was a randomized, double-blind, multicenter trial comparing the effects of a 4-year treatment with either lacidipine or atenolol on progression of carotid atherosclerosis in patients with moderate hypertension. SUA ... Read more >>

J. Hypertens. (Journal of hypertension)
[2019, 37(4):844-850]

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Left atrial function in elite athletes: A meta-analysis of two-dimensional speckle tracking echocardiographic studies.

Cesare Cuspidi, Marijana Tadic, Carla Sala, Elisa Gherbesi, Guido Grassi, Giuseppe Mancia,

BACKGROUND:We sought to investigate left atrial (LA) volume, function, and strain in elite athletes by a meta-analysis including echocardiographic studies that provided volumetric and strain analysis of LA phasic function. METHODS:The OVID-MEDLINE, PubMed, and Cochrane CENTRAL databases were searched for English-language articles without time restriction up to February 2018 through ... Read more >>

Clin Cardiol (Clinical cardiology)
[2019, 42(5):579-587]

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Highlights of the April issue.

Giuseppe Mancia,

J. Hypertens. (Journal of hypertension)
[2019, 37(4):657-659]

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Perioperative SBP changes during orthopedic surgery in the elderly: clinical implications.

Maria Koutsaki, Costas Thomopoulos, Apostolos Achimastos, Manolis Kallistratos, Chrisanthi Batistaki, Erifili Chatziagelaki, Eleftheria Soulioti, Leonidas Poulimenos, Stella Koutsaki, Argiro Mela, Giuseppe Mancia, Athanasios J Manolis,

OBJECTIVES:We aimed to determine SBP changes during the perioperative period of a scheduled knee surgery under regional anesthesia and the extent of perioperative (in-hospital) white-coat effect. METHODS:All patients (aged ≥60 years) underwent clinic SBP measurements during both cardiological and anesthesiological visits, while home SBP the week before admission was obtained. ... Read more >>

J. Hypertens. (Journal of hypertension)
[2019, :]

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Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry.

Felix Mahfoud, Michael Böhm, Roland Schmieder, Krzysztof Narkiewicz, Sebastian Ewen, Luis Ruilope, Markus Schlaich, Bryan Williams, Martin Fahy, Giuseppe Mancia,

AIMS:Several studies and registries have demonstrated sustained reductions in blood pressure (BP) after renal denervation (RDN). The long-term safety and efficacy after RDN in real-world patients with uncontrolled hypertension, however, remains unknown. The objective of this study was to assess the long-term safety and efficacy of RDN, including its effects ... Read more >>

Eur. Heart J. (European heart journal)
[2019, :]

Cited: 1 time

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