Full Text Journal Articles by
Author Gitonga Munene

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Prophylactic Enoxaparin Adjusted by Anti-Factor Xa Peak Levels Compared with Recommended Thromboprophylaxis and Rates of Clinically Evident Venous Thromboembolism in Surgical Oncology Patients.

Katherine Kramme, Paya Sarraf, Gitonga Munene,

BACKGROUND:Studies among populations at high risk of venous thromboembolism (VTE) have demonstrated that recommended doses for enoxaparin thromboprophylaxis are associated with high incidence of subprophylactic anti-factor Xa (anti-Xa) levels. This study examines the efficacy and safety of dose-adjusted enoxaparin guided by anti-Xa levels. STUDY DESIGN:Patients undergoing abdominal cancer operation had ... Read more >>

J. Am. Coll. Surg. (Journal of the American College of Surgeons)
[2020, 230(3):314-321]

Cited: 0 times

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The Role of Manual Dexterity and Cognitive Functioning in Enhancing Resident Operative Autonomy.

Saad Shebrain, Gulrez Mahmood, Gitonga Munene, Lisa Miller, John Collins, Robert Sawyer,

INTRODUCTION:Autonomy, both operative and nonoperative, is one of the most critical aspects of successful surgical training. Both surgeon and resident share the responsibility of achieving this goal. We hypothesize that operative autonomy is distinct and depends, for the most part, on the resident's manual dexterity, knowledge of, and preparation for ... Read more >>

J Surg Educ (Journal of surgical education)
[2019, 76(6):e66-e76]

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Short term outcomes and unintended benefits of establishing a HPB program at a university-affiliated community hospital.

Steven Lu, Richa Khatri, Brandon Tanner, Saad Shebrain, Gitonga Munene,

BACKGROUND:In hepato-pancreato-biliary (HPB) surgery higher volumes are associated with improved outcomes; however, there are limitations to regionalization. Here we report our experience establishing multidisciplinary HPB program at a university-affiliated community hospital. METHODS:This is a retrospective review of patients who underwent HPB surgery between 2015 and 2017. Chief residents' HPB case ... Read more >>

Am. J. Surg. (American journal of surgery)
[2019, 218(5):946-951]

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Trends in surgery and disparities in receipt of surgery for intrahepatic cholangiocarcinoma in the US: 2005-2014.

Eke Ransome, Li Tong, Jairo Espinosa, Jesse Chou, Vishal Somnay, Gitonga Munene,

Background:Intrahepatic cholangiocarcinoma (IHC) is a malignancy with an increasing incidence. Surgery is the only treatment modality associated with long term survival. The objective of this study is to utilize a nationwide representative database to quantify the trends in incidence, and surgery for IHC in the United States from 2004-2014, as ... Read more >>

J Gastrointest Oncol (Journal of gastrointestinal oncology)
[2019, 10(2):339-347]

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Surgical Transgastric Necrosectomy for Necrotizing Pancreatitis: A Single-stage Procedure for Walled-off Pancreatic Necrosis.

Michael Driedger, Nicholas J Zyromski, Brendan C Visser, Andrea Jester, Francis R Sutherland, Atilla Nakeeb, Elijah Dixon, Monica M Dua, Michael G House, David J Worhunsky, Gitonga Munene, Chad G Ball,

OBJECTIVE:The aim of this study was to evaluate the role of surgical transgastric necrosectomy (TGN) for walled-off pancreatic necrosis (WON) in selected patients. BACKGROUND:WON is a common consequence of severe pancreatitis and typically occurs 3 to 5 weeks after the onset of acute pancreatitis. When symptomatic, it can require intervention. ... Read more >>

Ann. Surg. (Annals of surgery)
[2020, 271(1):163-168]

Cited: 2 times

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The role of academic achievements and psychometric measures in the ranking process.

Saad Shebrain, Mohamed Arafeh, Gitonga Munene, Cynthia Shattuck, Lisa Miller, Steven Lu, David Schutter,

INTRODUCTION:Ranking candidates for residency positions is challenging. We hypothesize that applicant academic achievements and performance during the interview are equally important in the ranking process. METHODS:This is a retrospective study. Of 53 candidates interviewed during 2016-2017 cycle, 44 (83%) were ranked for 3 PGY1 positions. Each candidate was interviewed and ... Read more >>

Am. J. Surg. (American journal of surgery)
[2019, 217(3):568-571]

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Outcome and factors associated with aborted cytoreduction for peritoneal carcinomatosis.

Whitney Guerrero, Gitonga Munene, Paxton V Dickson, Zachary E Stiles, Johnathan Mays, Andrew M Davidoff, Evan S Glazer, David Shibata, Jeremiah L Deneve,

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) offers a potential cure for peritoneal carcinomatosis (PC), whereas aborted cytoreduction is associated with a poor outcome. We evaluate factors associated with aborted CRS procedures.An IRB approved retrospective review was performed from 12/2011 to 2/2016. Clinicopathologic variables and outcomes are described.Seventy-four patients underwent ... Read more >>

J Gastrointest Oncol (Journal of gastrointestinal oncology)
[2018, 9(4):664-673]

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Early experience with cytoreduction and hyperthermic intraperitoneal chemotherapy at a newly developed center for peritoneal malignancy.

Whitney L Guerrero, Gitonga Munene, Paxton V Dickson, Dina Darby, Andrew M Davidoff, Michael G Martin, Evan S Glazer, David Shibata, Jeremiah L Deneve,

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) has improved outcomes for patients with peritoneal carcinomatosis (PC). We present our experience from a newly developed peritoneal surface malignancy program.An IRB approved retrospective review was performed for the first 50 patients treated with CRS/HIPEC with clinicopathologic data described.Patients treated with CRS/HIPEC were ... Read more >>

J Gastrointest Oncol (Journal of gastrointestinal oncology)
[2018, 9(2):338-347]

Cited: 0 times

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The Impact of Ostomy Creation after Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy in a Newly Established Peritoneal Malignancy Program.

Zachary E Stiles, Nathan M Hinkle, Gitonga Munene, Paxton V Dickson, Andrew M Davidoff, Jeremiah L Deneve,

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) has improved outcomes for selected patients with peritoneal carcinomatosis and often requires ostomy creation. We examined the impact of ostomy creation in a newly established peritoneal malignancy program. A retrospective review was performed of CRS-HIPEC procedures from 2011 to 2016. Those who did ... Read more >>

Am Surg (The American surgeon)
[2018, 84(6):776-782]

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Understanding Disparities in Breast Cancer Care in Memphis, Tennessee.

Elena P Lamb, F Elizabeth Pritchard, Simonne S Nouer, Elizabeth A Tolley, Brandon S Boyd, Jesse T Davidson, Gitonga Munene, Martin D Fleming,

Although significant progress has been made in improving breast cancer survival, disparities among racial, ethnic, and underserved groups still exist. The goal of this investigation is to quantify racial disparities in the context of breast cancer care, examining the outcomes of recurrence and mortality in the city of Memphis. Patients ... Read more >>

Am Surg (The American surgeon)
[2018, 84(5):620-627]

Cited: 1 time

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Coagulation profile following liver resection: Does liver cirrhosis affect thromboelastography?

Brandon Tanner, Steven Lu, Guston Zervoudakis, Alyssa Woodwyk, Gitonga Munene,

BACKGROUND:Thromboelastography has called into question the coagulopathy seen following partial hepatectomy. However the coagulation profile in cirrhotic livers has not been studied. Our objective was to determine the coagulation profile following partial hepatectomy in normal and cirrhotic livers. METHODS:Patients undergoing liver resection were prospectively enrolled in the study. The prothrombin ... Read more >>

Am. J. Surg. (American journal of surgery)
[2018, 215(3):406-409]

Cited: 0 times

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An unusual case of jaundice: Biliary tumor thrombus in fibrolamellar hepatocellular carcinoma.

Jairo A Espinosa, Alex Merlo, Mohamed-Omar Arafeh, Gitonga Munene,

Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare and unique variant of hepatocellular carcinoma (HCC) whose presentation remains inadequately described. We present a resectable case of FL-HCC which involved tumor thrombus of the common bile duct.A 27 year-old male presenting with jaundice, abdominal pain, vomiting, hepatic dysfunction and hyperbilirubinemia was found ... Read more >>

Int J Surg Case Rep (International journal of surgery case reports)
[2017, 36:50-54]

Cited: 1 time

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A Bayesian network and heuristic approach for systematic characterization of radiotherapy receipt after breast-conservation surgery.

Milton Soto-Ferrari, Diana Prieto, Gitonga Munene,

Breast-conservation surgery with radiotherapy is a treatment highly recommended by the guidelines from the National Comprehensive Cancer Network. However, several variables influence the final receipt of radiotherapy and it might not be administered to breast cancer patients. Our objective is to propose a systematic framework to identify the clinical and ... Read more >>

BMC Med Inform Decis Mak (BMC medical informatics and decision making)
[2017, 17(1):93]

Cited: 2 times

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The Impact of Early Recurrence on Quality of Life after Cytoreduction with HIPEC.

Nathan M Hinkle, Vandana Botta, John P Sharpe, Paxton Dickson, Jeremiah Deneve, Gitonga Munene,

Improved oncological outcomes after cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in highly selected patients have been well documented. The extensive nature of the procedure adversely affects quality of life (QoL). The aim of this study is to longitudinally evaluate QoL following CRS/HIPEC. This is a retrospective review of ... Read more >>

Am Surg (The American surgeon)
[2017, 83(6):633-639]

Cited: 1 time

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Cytoreduction with hyperthermic intraperitoneal chemotherapy: an appraisal of outcomes and cost at a newly established peritoneal malignancy program.

Nathan M Hinkle, James MacDonald, John P Sharpe, Paxton Dickson, Jeremiah Deneve, Gitonga Munene,

Outcome measures after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) for peritoneal carcinomatosis in established centers are well defined. However, results from newly emerging US centers have not been reported.This is a retrospective review of a prospectively maintained database of patients with peritoneal malignancies undergoing CRS/HIPEC.Fifty-six patients underwent exploratory laparotomy ... Read more >>

Am. J. Surg. (American journal of surgery)
[2016, 212(3):413-418]

Cited: 2 times

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Locally Advanced, Unresectable Squamous Cell Carcinoma of the Gallbladder.

Timothy J Weatherall, Moon Fenton, Gitonga Munene, Paxton V Dickson, Jeremiah L Deneve,

Primary squamous cell carcinoma (SCC) of the gallbladder is a rare malignancy of the gallbladder, accounting for less than 5% of gallbladder pathology. Initial presentation is often similar to adenocarcinoma of the gallbladder. SCC tends to be more locally aggressive, however, and possesses a worse prognosis than adenocarcinoma. We report ... Read more >>

Case Rep Surg (Case reports in surgery)
[2015, 2015:424650]

Cited: 2 times

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Neuroendocrine tumors, version 1.2015.

Matthew H Kulke, Manisha H Shah, Al B Benson, Emily Bergsland, Jordan D Berlin, Lawrence S Blaszkowsky, Lyska Emerson, Paul F Engstrom, Paul Fanta, Thomas Giordano, Whitney S Goldner, Thorvardur R Halfdanarson, Martin J Heslin, Fouad Kandeel, Pamela L Kunz, Boris W Kuvshinoff, Christopher Lieu, Jeffrey F Moley, Gitonga Munene, Venu G Pillarisetty, Leonard Saltz, Julie Ann Sosa, Jonathan R Strosberg, Jean-Nicolas Vauthey, Christopher Wolfgang, James C Yao, Jennifer Burns, Deborah Freedman-Cass, ,

Neuroendocrine tumors (NETs) comprise a broad family of tumors that may or may not be associated with symptoms attributable to hormonal hypersecretion. The NCCN Clinical Practice Guidelines in Oncology for Neuroendocrine Tumors discuss the diagnosis and management of both sporadic and hereditary NETs. This selection from the guidelines focuses on ... Read more >>

J Natl Compr Canc Netw (Journal of the National Comprehensive Cancer Network : JNCCN)
[2015, 13(1):78-108]

Cited: 115 times

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The evolving role of surgery for gastric lymphoma: from curative resection to surgical management of complications.

Elena M Paulus, Martin D Fleming, Ashley A Hendrix, Jeremiah L Deneve, Paxton V Dickson, Alex Mathew, Michael G Martin, Gitonga Munene,

Am Surg (The American surgeon)
[2014, 80(11):E322-4]

Cited: 2 times

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Management of a ruptured mucinous mesenteric cyst with hyperthermic intraperitoneal chemotherapy.

John Nelson, Jeremiah Deneve, Paxton Dickson, Pamela Sylvestre, Gitonga Munene,

Mesenteric cysts are rare intra-abdominal cysts that are generally regarded as benign, and the incidence of malignancy is often cited to be 3%. The typical recommendation for treatment is complete excision to minimize recurrence. Excision can be performed laparoscopically, but this can lead to intra-abdominal dissemination of the cyst contents. ... Read more >>

Tumori (Tumori)
[2014, 100(2):e55-8]

Cited: 0 times

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Sequential preoperative hepatic vein embolization after portal vein embolization for extended left hepatectomy in colorectal liver metastases.

Gitonga Munene, Robyn D Parker, John Larrigan, Jason Wong, Francis Sutherland, Elijah Dixon,

BACKGROUND: The role of portal vein embolization to increase future liver remnant (FLR) is well-established in the treatment of colorectal liver metastases. However, the role of hepatic vein embolization is unclear. CASE REPORT: A patient with colorectal liver metastases received neoadjuvant chemotherapy prior to attempted resection. At the time of ... Read more >>

World J Surg Oncol (World journal of surgical oncology)
[2013, 11:134]

Cited: 7 times

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Disparities in the surgical treatment of colorectal liver metastases.

Gitonga Munene, Robyn D Parker, Abdel Aziz Shaheen, Robert P Myers, May Lynn Quan, Chad G Ball, Elijah Dixon,

BACKGROUND:Hepatectomy is an accepted standard of care for patients with resectable colorectal liver metastases (CLM). Given that it is unclear whether disparities exist between different patient populations, a population-based analysis was performed to analyze this issue with regards to resection rates and surgical mortality in patients with CLM. METHODS:Using the ... Read more >>

J Natl Med Assoc (Journal of the National Medical Association)
[2013, 105(2):128-137]

Cited: 9 times

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The quality of life trajectory of resected gastric cancer.

Gitonga Munene, Wesley Francis, Sheila N Garland, Guy Pelletier, Lloyd A Mack, Oliver F Bathe,

BACKGROUND: Few studies describe quality of life (QoL) outcomes following gastrectomy for gastric cancer using a validated instrument. The gastric cancer module for the Functional Assessment of Cancer Therapy system of QoL measurement tools (FACT-Ga) was utilized to determine the changes in QoL following gastrectomy, and during the disease course. ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2012, 105(4):337-341]

Cited: 13 times

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Canadian Society of Surgical Oncology Seventeenth Annual Scientific Meeting: Apr. 29, 2011, Delta Chelsea Hotel, Toronto, Ont.

Can J Surg (Canadian journal of surgery. Journal canadien de chirurgie)
[2011, 54(3):209-213]

Cited: 0 times

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Open transgastric debridement and internal drainage of symptomatic non-infected walled-off pancreatic necrosis.

Gitonga Munene, Elijah Dixon, Francis Sutherland,

BACKGROUND: The best treatment options for walled-off pancreatic necrosis (WOPN) are not well defined. A retrospective study of patients treated for WOPN with transgastric debridement and internal drainage was undertaken. METHODS: Patients with symptomatic non-infected WOPN treated with open transgastric debridement and internal drainage were evaluated. RESULTS: In all, 51 ... Read more >>

HPB (Oxford) (HPB : the official journal of the International Hepato Pancreato Biliary Association)
[2011, 13(4):234-239]

Cited: 4 times

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Neoadjuvant radiotherapy and reconstruction using autologous vein graft for the treatment of inferior vena cava leiomyosarcoma.

Gitonga Munene, Lloyd A Mack, Randy D Moore, Walley J Temple,

BACKGROUND AND OBJECTIVES: Inferior vena cava (IVC) leiomyosarcomas are rare and are a relatively small subset of retroperitoneal sarcomas. The current approach is resection and ligation or reconstruction of the IVC. This study was undertaken to analyze the outcomes associated with the use of neoadjuvant radiotherapy and IVC reconstruction in ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2011, 103(2):175-178]

Cited: 9 times

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