Full Text Journal Articles by
Author Gilberto Gerra

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Managing dual disorders: a statement by the Informal Scientific Network, UN Commission on Narcotic Drugs.

Nora D Volkow, Marta Torrens, Vladimir Poznyak, Elizabeth Sáenz, Anja Busse, Wataru Kashino, Dzmitry Krupchanka, Devora Kestel, Giovanna Campello, Gilberto Gerra,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2020, 19(3):396-397]

Cited: 0 times

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Prescription psychostimulants for the treatment of stimulant use disorder: a systematic review and meta-analysis.

Vitor S Tardelli, Adam Bisaga, Felipe B Arcadepani, Gilberto Gerra, Frances R Levin, Thiago M Fidalgo,

RATIONALE:Agonist-based pharmacologic intervention is an accepted approach in treatment of opioid and tobacco use disorders. OBJECTIVES:We conducted a systematic review and meta-analysis to evaluate usefulness of an agonist approach as treatment of (psycho)stimulant use disorder (PSUD). METHODS:We reviewed PubMed/Medline, LILACS, and ClinicalTrials.gov databases searching for randomized, double-blind, placebo-controlled, parallel-design studies ... Read more >>

Psychopharmacology (Berl.) (Psychopharmacology)
[2020, 237(8):2233-2255]

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Strong families: a new family skills training programme for challenged and humanitarian settings: a single-arm intervention tested in Afghanistan.

Karin Haar, Aala El-Khani, Virginia Molgaard, Wadih Maalouf, ,

BACKGROUND:Children living in challenged humanitarian settings (including those in rural/underserved areas, the displaced, refugees, in conflict/post conflict situations) are at greater risk of mental health difficulties or behavioural problems, with caregivers acting as their main protective factors. While many family skills programmes exist, very few were developed for, or piloted ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):634]

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COVID-19 and Substance Use Disorders: Recommendations to a Comprehensive Healthcare Response. An International Society of Addiction Medicine Practice and Policy Interest Group Position Paper.

Ali Farhoudian, Alexander Baldacchino, Nicolas Clark, Gilberto Gerra, Hamed Ekhtiari, Geert Dom, Azarakhsh Mokri, Mandana Sadeghi, Pardis Nematollahi, Maryanne Demasi, Christian G Schütz, Seyed Mohammadreza Hash-Emian, Payam Tabarsi, Susanna Galea-Singer, Giuseppe Carrà, Thomas Clausen, Christos Kouimtsidis, Serenella Tolomeo, Seyed Ramin Radfar, Emran Mohammad Razaghi,

Coronavirus Disease 2019 (COVID-19) is escalating all over the world and has higher morbidities and mortalities in certain vulnerable populations. People Who Use Drugs (PWUD) are a marginalized and stigmatized group with weaker immunity responses, vulnerability to stress, poor health conditions, high-risk behaviors, and lower access to health care services. ... Read more >>

(Basic and clinical neuroscience)
[2020, 11(2):133-150]

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COVID-19 and Substance Use Disorder: Study Protocol for the International Society of Addiction Medicine Practice and Policy Interest Group Global Survey.

Alexander Baldacchino, Seyed Ramin Radfar, Cornelis De Jong, Parnian Rafei, Masud Yunesian, Gilberto Gerra, Kathleen Brady, Mohsen Ebrahimi, Mehrnoosh Vahidi, Arash Khojasteh Zonoozi, Hossein Mohaddes Ardabili, Anja Busse, Elizabeth Saenz, Giovanna Campello, Kamran Niaz, Hamed Ekhtiari, Ali Farhoudian,

Introduction:As one of the major health problems in the present century, the COVID-19 pandemic affected all parts of the global communities and the health of substance users are potentially at a greater risk of harm. This global study has been designed and conducted by the International Society of Addiction Medicine ... Read more >>

(Basic and clinical neuroscience)
[2020, 11(2):155-162]

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Socioeconomic Status, Parental Education, School Connectedness and Individual Socio-Cultural Resources in Vulnerability for Drug Use among Students.

Gilberto Gerra, Elisa Benedetti, Giuliano Resce, Roberta Potente, Arianna Cutilli, Sabrina Molinaro,

BACKGROUND AND AIMS:Families who live in a disadvantaged socioeconomic situation frequently face substandard housing, unsafe neighborhoods, inadequate schools and more stress in their daily lives than more affluent families, with a host of psychological and developmental consequences that can hinder their children's development in many ways. However, the measurement of ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(4):]

Cited: 0 times

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Addressing the opioid crisis globally.

Nora D Volkow, María Elena Medina-Mora Icaza, Vladimir Poznyak, Shekhar Saxena, Gilberto Gerra, ,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2019, 18(2):231-232]

Cited: 2 times

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Determination of oxycodone and its major metabolites in haematic and urinary matrices: Comparison of traditional and miniaturised sampling approaches.

Michele Protti, Maria Carmen Catapano, Boaz Gedaliahu Samolsky Dekel, James Rudge, Gilberto Gerra, Lorenzo Somaini, Roberto Mandrioli, Laura Mercolini,

Oxycodone is a widely prescribed, full agonist opioid analgesic. As such, it is used clinically to treat different kinds of painful conditions, with a relatively high potential for doping practices in athletes. In this paper, different classic and innovative miniaturised matrices from blood and urine have been studied and compared, ... Read more >>

J Pharm Biomed Anal (Journal of pharmaceutical and biomedical analysis)
[2018, 152:204-214]

Cited: 4 times

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Report on the International Workshop on Drug Prevention and Treatment in Rural Settings Organized by United Nation Office on Drugs and Crime (UNODC) and World Health Organization (WHO).

Giulia Milano, Elizabeth Saenz, Nicolas Clark, Anja Busse, John Gale, Giovanna Campello, Elizabeth Mattfeld, Wadih Maalouf, Hanna Heikkila, Antonietta Martelli, Brian Morales, Gilberto Gerra,

Very little evidence has been reported in literature regarding the misuse of substances in rural areas. Despite the common perception of rural communities as a protective and risk-mitigating environment, the scientific literature demonstrated the existence of many risk factors in rural communities. The Drug Prevention and Health Branch (DHB) of ... Read more >>

Subst Use Misuse (Substance use & misuse)
[2017, 52(13):1801-1807]

Cited: 2 times

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Drug use disorders: impact of a public health rather than a criminal justice approach.

Nora D Volkow, Vladimir Poznyak, Shekhar Saxena, Gilberto Gerra, ,

(World psychiatry : official journal of the World Psychiatric Association (WPA))
[2017, 16(2):213-214]

Cited: 6 times

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Treatment of Benzodiazepine Dependence.

Fabio Lugoboni, Gilberto Gerra, Stefano Tamburin,

N. Engl. J. Med. (The New England journal of medicine)
[2017, 376(24):2399]

Cited: 1 time

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Co-occurring Attention Deficit Hyperactivity Disorder symptoms in adults affected by heroin dependence: Patients characteristics and treatment needs.

Fabio Lugoboni, Frances Rudnick Levin, Maria Chiara Pieri, Matteo Manfredini, Lorenzo Zamboni, Lorenzo Somaini, Gilberto Gerra, Gruppo InterSert Collaborazione Scientifica Gics,

Attention Deficit Hyperactivity Disorder (ADHD) is a risk for substance use disorders. The aim of this study was to investigate the association between adult ADHD symptoms, opioid use disorder, life dysfunction and co-occurring psychiatric symptoms. 1057 heroin dependent patients on opioid substitution treatment participated in the survey. All patients were ... Read more >>

Psychiatry Res (Psychiatry research)
[2017, 250:210-216]

Cited: 3 times

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Dried haematic microsamples and LC-MS/MS for the analysis of natural and synthetic cannabinoids.

Michele Protti, James Rudge, Angelo Eliseo Sberna, Gilberto Gerra, Laura Mercolini,

Synthetic cannabinoids are new psychoactive substances (NPS) with similar effects when compared to natural ones found in Cannabis derivatives. They have rapidly integrated into the illicit market, often sold as alternatives under international control. The need to identify and quantify an unprecedented and growing number of new compounds represents a ... Read more >>

J Chromatogr B Analyt Technol Biomed Life Sci (Journal of chromatography. B, Analytical technologies in the biomedical and life sciences)
[2017, 1044-1045:77-86]

Cited: 4 times

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Increased oxytocin levels among abstinent heroin addicts: Association with aggressiveness, psychiatric symptoms and perceived childhood neglect.

Lidia M Gerra, Gilberto Gerra, Laura Mercolini, Matteo Manfredini, Lorenzo Somaini, Chiara M Pieri, Maina Antonioni, Michele Protti, Paolo Ossola, Carlo Marchesi,

A disruption of the oxytocin system seems to affect a variety of brain functions including emotions, mood and social behavior possibly underlying severe social deficits and susceptibility for substance use and mental health disorders. Early life adversity, such as insecure attachment in childhood, has been suggested to influence oxytocin tone ... Read more >>

Prog Neuropsychopharmacol Biol Psychiatry (Progress in neuro-psychopharmacology & biological psychiatry)
[2017, 75:70-76]

Cited: 2 times

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Perceived parental care during childhood, ACTH, cortisol and nicotine dependence in the adult.

Gilberto Gerra, Matteo Manfredini, Lorenzo Somaini, Giulia Milano, Roberto Ciccocioppo, Claudia Donnini,

Studies evidenced the relationship between adverse childhood experiences (ACEs) and tobacco smoking in adulthood. An appropriate parenting style has been found to be associated with children's less frequent tobacco consumption. Hypothalamus-pituitary-adrenal (HPA) axis hyperactivity could represent the potential link between ACEs, mood disorders and smoking susceptibility. We studied a sample ... Read more >>

Psychiatry Res (Psychiatry research)
[2016, 245:458-465]

Cited: 1 time

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Sexual Dysfunction in Men Receiving Methadone Maintenance Treatment: Clinical History and Psychobiological Correlates.

Gilberto Gerra, Matteo Manfredini, Lorenzo Somaini, Icro Maremmani, Claudio Leonardi, Claudia Donnini,

A variety of studies evidenced a relationship between drug use disorders and sexual dysfunction. In particular, heroin and opioid agonist medications to treat heroin dependence have been found to be associated with erectile dysfunction and reduced libido. Controversial findings also indicate the possibility of factors other than the pharmacological effects ... Read more >>

Eur Addict Res (European addiction research)
[2016, 22(3):163-175]

Cited: 6 times

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Analysis of γ-hydroxy butyrate by combining capillary electrophoresis-indirect detection and wall dynamic coating: application to dried matrices.

Maria A Saracino, Maria C Catapano, Rosa Iezzi, Lorenzo Somaini, Gilberto Gerra, Laura Mercolini,

γ-Hydroxybutyric acid (GHB) is a powerful central nervous system depressant, currently used in medicine for the treatment of narcolepsy and alcohol dependence. In recent years, it has gained popularity among illegal club drugs, mainly because of its euphoric effects as well as doping agent and date rape drug. The purpose ... Read more >>

Anal Bioanal Chem (Analytical and bioanalytical chemistry)
[2015, 407(29):8893-8901]

Cited: 3 times

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Take-home emergency naloxone to prevent deaths from heroin overdose.

John Strang, Sheila M Bird, Paul Dietze, Gilberto Gerra, A Thomas McLellan,

BMJ (BMJ (Clinical research ed.))
[2014, 349:g6580]

Cited: 17 times

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A comprehensive approach to addiction medicine as an appropriate response to the HIV epidemic among drug users.

Gilberto Gerra,

The services for drug-dependence treatment and care, particularly in low-income countries, should not be fragmented and uncoordinated. A basic package of interventions should be provided in the same place and managed by the same team, with a one-stop shop approach. The services for substance use disorders should be appealing, accessible, ... Read more >>

J Food Drug Anal (Journal of food and drug analysis)
[2013, 21(4):S109-S112]

Cited: 0 times

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Multi-matrix assay of cortisol, cortisone and corticosterone using a combined MEPS-HPLC procedure.

Maria A Saracino, Corrado Iacono, Lorenzo Somaini, Gilberto Gerra, Nadia Ghedini, Maria A Raggi,

The development and validation of a bioanalytical assay for the simultaneous determination of cortisol, cortisone and corticosterone levels in several matrices, such as saliva, plasma, blood and urine samples have been described. The method is based on a rapid test which combines a microextraction by packed sorbent procedure and liquid ... Read more >>

J Pharm Biomed Anal (Journal of pharmaceutical and biomedical analysis)
[2014, 88:643-648]

Cited: 6 times

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Association between gene variants and response to buprenorphine maintenance treatment.

Gilberto Gerra, Lorenzo Somaini, Claudio Leonardi, Elena Cortese, Icro Maremmani, Matteo Manfredini, Claudia Donnini,

A variety of studies were addressed to differentiate responders and non-responders to substitution treatment among heroin dependent patients, without conclusive findings. In particular, preliminary pharmacogenetic findings have been reported to predict treatment effectiveness in mental health and substance use disorders. Aim of the present study was to investigate the possible ... Read more >>

Psychiatry Res (Psychiatry research)
[2014, 215(1):202-207]

Cited: 12 times

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Voluntary treatment, not detention, in the management of opioid dependence.

Nicolas Clark, Anja Busse, Gilberto Gerra,

Bull. World Health Organ. (Bulletin of the World Health Organization)
[2013, 91(2):146-147]

Cited: 4 times

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A novel test using dried blood spots for the chromatographic assay of methadone.

Maria Addolorata Saracino, Chiara Marcheselli, Lorenzo Somaini, Maria Chiara Pieri, Gilberto Gerra, Anna Ferranti, Maria Augusta Raggi,

A novel test has been developed for the analysis of methadone in dried blood spot specimens from patients undergoing methadone maintenance treatment. An isocratic reversed-phase high-performance liquid chromatography method with coulometric detection has been optimized for the determination of methadone. The clean-up of dried blood spots was performed by means ... Read more >>

Anal Bioanal Chem (Analytical and bioanalytical chemistry)
[2012, 404(2):503-511]

Cited: 9 times

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Pregabalin reduces cocaine self-administration and relapse to cocaine seeking in the rat.

Giordano de Guglielmo, Andrea Cippitelli, Lorenzo Somaini, Gilberto Gerra, Hongwu Li, Serena Stopponi, Massimo Ubaldi, Marsida Kallupi, Roberto Ciccocioppo,

Pregabalin (Lyrica™) is a structural analog of γ-aminobutyric acid (GABA) and is approved by the FDA for partial epilepsy, neuropathic pain and generalized anxiety disorders. Pregabalin also reduces excitatory neurotransmitter release and post-synaptic excitability. Recently, we demonstrated that pregabalin reduced alcohol intake and prevented relapse to the alcohol seeking elicited ... Read more >>

Addict Biol (Addiction biology)
[2013, 18(4):644-653]

Cited: 16 times

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Interventions, policies and evidence: taking an experimental look at international drug control.

Gilberto Gerra, Sandeep Chawla,

Subst Use Misuse (Substance use & misuse)
[2012, 47(8-9):865-867]

Cited: 0 times

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