Full Text Journal Articles by
Author Gianluca Massaro

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Cardiovascular medicine: a year in review.

Andrea Matteucci, Michela Bonanni, Francesco Versaci, Giacomo Frati, Mariangela Peruzzi, Giuseppe Sangiorgi, Giuseppe Biondi-Zoccai, Gianluca Massaro,

Cardiovascular medicine is facing several challenges in the current era, dominated by the rapid spread of a previously unknown virus around the world. Indeed, the 2020 COVID-19 pandemic set the course of cardiovascular science and education in an extraordinary way, hogging the attention of the medical community. Notably, while COVID-19 ... Read more >>

Minerva Cardiol Angiol (Minerva cardiology and angiology)
[2021, :]

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Clinical Features and Management of COVID-19 Associated Hypercoagulability

Gianluca Massaro, Dalgisio Lecis, Eugenio Martuscelli, Gaetano Chiricolo, Giuseppe Massimo Sangiorgi,

Synopsis Covid-19 is an acute respiratory disease of viral origin caused by Sars-Cov2. This disease is associated with a hypercoagulable state resulting in arterial and venous thrombotic events. The latter are more frequent, especially in patients who develop a severe form of the disease and are associated with an increased ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

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A thymic hyperplasia-related reversible complete atrioventricular block: When compression is more important than compressor.

Gianluca Massaro, Giuseppe Stifano, Vincenzo Ambrogi, Lucia Anemona, Enrica Giuliana Mariano, Gaetano Chiricolo, Eugenio Martuscelli, Giuseppe Massimo Sangiorgi,

A 19-year-old patient presented for syncope with third-degree AV block (TDAVB) at ECG. A chest-CT showed a thymic mass that could be responsible for TDAVB due to extrinsic vagal nerve compression. Thymectomy led to complete AV block resolution. An extrinsic vagal compression mechanism should be considered among causes of complete ... Read more >>

J Electrocardiol (Journal of electrocardiology)
[2021, 69:68-70]

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Expanding the role of fractional flow reserve derived from computed tomography (FFRCT) for the non-invasive imaging of patients with coronary stents: rise of the machines?

Andrea Matteucci, Gianluca Massaro, Mamas A Mamas, Giuseppe Biondi-Zoccai,

Eur Radiol (European radiology)
[2021, 31(9):6589-6591]

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Home Management of Heart Failure and Arrhythmias in Patients with Cardiac Devices during Pandemic.

Andrea Matteucci, Michela Bonanni, Marco Centioni, Federico Zanin, Francesco Geuna, Gianluca Massaro, Giuseppe Sangiorgi,

<h4>Background</h4>The in-hospital management of patients with cardiac implantable electronic devices (CIEDs) changed early in the COVID-19 pandemic. Routine in-hospital controls of CIEDs were converted into remote home monitoring (HM). The aim of our study was to investigate the impact of the lockdown period on CIEDs patients and its influence on ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(8):]

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Electrocardiographic modifications and cardiac involvement in COVID-19 patients: results from an Italian cohort.

Andrea Matteucci, Gianluca Massaro, Domenico Sergi, Michela Bonanni, Giuseppe Stifano, Matteo Matino, Bartolomeo Zerillo, Paola Rogliani, Francesco Romeo,

<h4>Aim</h4>The aim of this study was to detect predisposing CV risks factors and ECGs changes in COVID-19 patients.<h4>Methods</h4>The study population included 60 noncritically ill patients with COVID-19 pneumonia admitted to our hospital between 16 March and 11 May 2020. Electrographic changes, evaluated from ECGs acquired at admission and at 7 ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2021, 22(3):190-196]

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MiR-423 is differentially expressed in patients with stable and unstable coronary artery disease: A pilot study.

Barbara Rizzacasa, Elena Morini, Ruggiero Mango, Chiara Vancheri, Simone Budassi, Gianluca Massaro, Sara Maletta, Massimiliano Macrini, Silvio D'Annibale, Francesco Romeo, Giuseppe Novelli, Francesca Amati,

Coronary artery disease (CAD) and acute myocardial infarction (AMI) are the leading causes of death worldwide. Since only a subset of CAD patients develops myocardial infarction, it is likely that unique factors predispose to AMI. Circulating microRNAs represent diagnostic powerful biomarkers for detection of heart injuries and patients' risk stratification. ... Read more >>

PLoS One (PloS one)
[2019, 14(5):e0216363]

Cited: 10 times

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Inflammasome, T Lymphocytes and Innate-Adaptive Immunity Crosstalk: Role in Cardiovascular Disease and Therapeutic Perspectives.

Daniela Pedicino, Ada Francesca Giglio, Aureliano Ruggio, Gianluca Massaro, Alessia D'Aiello, Francesco Trotta, Claudia Lucci, Francesca Graziani, Luigi Marzio Biasucci, Filippo Crea, Giovanna Liuzzo,

Over the past few decades, lot of evidences have shown atherosclerosis as a chronic progressive disease with an exquisite inflammatory feature. More recently, the role of innate immune response in the onset and progression of coronary artery disease (CAD) and an adaptive immunity imbalance, mostly involving T cell sub-sets, have ... Read more >>

Thromb Haemost (Thrombosis and haemostasis)
[2018, 118(8):1352-1369]

Cited: 3 times

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Carotid Doppler sonography: additional tool to assess hemodynamic improvement after transcatheter aortic valve implantation.

Valeria Cammalleri, Francesco Romeo, Massimo Marchei, Andrea Anceschi, Gianluca Massaro, Saverio Muscoli, Francesca De Persis, Massimiliano Macrini, Gian P Ussia,

PURPOSE:The aim of our study was to assess the arterial cerebral blood flow variations in patients with aortic valve stenosis, immediately after the transcatheter aortic valve implantation (TAVI). METHODS:The study population includes 62 consecutive patients who underwent TAVI for aortic valve stenosis (95%) and sugical bioprosthesis degeneration (5%). Carotid Doppler ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2018, 19(3):113-119]

Cited: 2 times

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Increased PTPN22 expression and defective CREB activation impair regulatory T-cell differentiation in non-ST-segment elevation acute coronary syndromes.

Davide Flego, Anna Severino, Francesco Trotta, Marco Previtero, Sarassunta Ucci, Chiara Zara, Gianluca Massaro, Daniela Pedicino, Luigi M Biasucci, Giovanna Liuzzo, Filippo Crea,

<h4>Background</h4>Critical impairment of adaptive immune response has been observed in patients with acute coronary syndromes (ACS) with reduced expansion of regulatory T cells (Treg) and enhanced effector T-cell responsiveness, both associated with poorer outcomes.<h4>Objectives</h4>This study investigated the mechanisms underlying T-cell dysregulation in ACS.<h4>Methods</h4>We evaluated both early and downstream T-cell receptor ... Read more >>

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2015, 65(12):1175-1186]

Cited: 19 times

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Altered CD31 expression and activity in helper T cells of acute coronary syndrome patients.

Davide Flego, Anna Severino, Francesco Trotta, Marco Previtero, Sara Ucci, Chiara Zara, Daniela Pedicino, Gianluca Massaro, Luigi M Biasucci, Giovanna Liuzzo, Filippo Crea,

In acute coronary syndrome (ACS), T cell abnormalities are associated to a worse outcome. Loss of inhibitory activity of CD31, an Ig-like adhesion molecule, on peripheral leukocytes has been found to enhance atherosclerosis in experimental models. In this study, we examined the expression of CD31 on T cells, and its ... Read more >>

Basic Res Cardiol (Basic research in cardiology)
[2014, 109(6):448]

Cited: 11 times

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Adaptive immunity, inflammation, and cardiovascular complications in type 1 and type 2 diabetes mellitus.

Daniela Pedicino, Giovanna Liuzzo, Francesco Trotta, Ada Francesca Giglio, Simona Giubilato, Francesca Martini, Francesco Zaccardi, Giuseppe Scavone, Marco Previtero, Gianluca Massaro, Pio Cialdella, Maria Teresa Cardillo, Dario Pitocco, Giovanni Ghirlanda, Filippo Crea,

Diabetes mellitus (DM) is a pandemics that affects more than 170 million people worldwide, associated with increased mortality and morbidity due to coronary artery disease (CAD). In type 1 (T1) DM, the main pathogenic mechanism seems to be the destruction of pancreatic β -cells mediated by autoreactive T-cells resulting in ... Read more >>

J Diabetes Res (Journal of diabetes research)
[2013, 2013:184258]

Cited: 28 times

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