Full Text Journal Articles by
Author Gianfranco Mitacchione

Advertisement

Find full text journal articles






Arrhythmogenic Risk and Mechanisms of QT Prolonging Drugs to Treat COVID-19

Marco Schiavone, Alessio Gasperetti, Elisa Gherbesi, Luca Bergamaschi, Roberto Arosio, Gianfranco Mitacchione, Maurizio Viecca, Giovanni B. Forleo,

While looking for a “magic bullet” to treat COVID-19, the massive off-label use of several of drugs in COVID-19, including repurposed antimalarial drugs, immunosuppressive agents, anti-virals and antibacterial agents, have generated concerns in the early phase of the pandemic due a possible arrhythmogenic effects in relation to QTc interval prolongation. ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Micra-AV leadless pacemaker and atrioventricular (dys)synchrony: A stepwise process.

Gianfranco Mitacchione, Marco Schiavone, Alessio Gasperetti, Diego Ruggiero, Marialessia Denora, Maurizio Viecca, Giovanni Battista Forleo,

Leadless pacemakers have become a major breakthrough in the management of bradyarrhythmia as an attractive alternative to the standard transvenous pacemakers, but safety and long-term outcomes of the new Micra-AV, which is capable guarantee atrioventricular (AV) synchrony, have been poorly described. Hence, we describe how we managed a 57-year-old patient ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2021, 44(10):1738-1742]

Cited: 0 times

View full text PDF listing >>



Advertisement

Intraprocedural PRAETORIAN score for early assessment of S-ICD implantation: A proof-of-concept study.

Alessio Gasperetti, Marco Schiavone, Mauro Biffi, Michela Casella, Paolo Compagnucci, Gianfranco Mitacchione, Andrea Angeletti, Julia Vogler, Riccardo Proietti, Matteo Ziacchi, Antonio Dello Russo, Andrea Natale, Roland R Tilz, Giovanni B Forleo,

<h4>Introduction</h4>The PRAETORIAN score (PS) was developed to assess the implant position and predict defibrillation success of the subcutaneous implantable cardioverter defibrillators (S-ICD). The main critique moved to the routine use of PS has been its postprocedural timing, that limits its usefulness on procedure guidance. The aim of this proof-of-concept study ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2021, 32(11):3035-3041]

Cited: 0 times

View full text PDF listing >>



Second-generation laser balloon ablation for the treatment of atrial fibrillation assessed by continuous rhythm monitoring: the LIGHT-AF study.

Giovanni Rovaris, Giuseppe Ciconte, Marco Schiavone, Gianfranco Mitacchione, Alessio Gasperetti, Elena Piazzi, Gabriele Negro, Elisabetta Montemerlo, Roberto Rondine, Mattia Pozzi, Mirko Casiraghi, Sergio De Ceglia, Daniele Giacopelli, Maurizio Viecca, Gabriele Vicedomini, Giovanni B Forleo, Carlo Pappone,

<h4>Aims</h4>Balloon-based technologies have been developed to simplify catheter ablation of atrial fibrillation (AF), to improve the clinical outcome of the procedure and to achieve durable pulmonary vein isolation (PVI). The objective of this study is to evaluate the safety and efficacy of second-generation laser balloon (LB2) ablation in the treatment ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2021, 23(9):1380-1390]

Cited: 1 time

View full text PDF listing >>



Long-term complications in patients implanted with subcutaneous implantable cardioverter-defibrillators: Real-world data from the extended ELISIR experience.

Alessio Gasperetti, Marco Schiavone, Matteo Ziacchi, Julia Vogler, Alexander Breitenstein, Mikael Laredo, Pietro Palmisano, Danilo Ricciardi, Gianfranco Mitacchione, Paolo Compagnucci, Antonio Bisignani, Andrea Angeletti, Michela Casella, Francesco Picarelli, Thomas Fink, Lukas Kaiser, Samer Hakmi, Leonardò Calò, Carlo Pignalberi, Luca Santini, Carlo Lavalle, Ennio Pisanò, Iacopo Olivotto, Claudio Tondo, Antonio Curnis, Antonio Dello Russo, Nicolas Badenco, Jan Steffel, Charles J Love, Roland Tilz, Giovanni Forleo, Mauro Biffi,

<h4>Background</h4>Recently, the Food and Drug Administration issued a recall for the subcutaneous implantable cardioverter-defibrillator (S-ICD) because of the possibility of lead ruptures and accelerated battery depletion.<h4>Objective</h4>The aim of this study was to evaluate device-related complications over time in a large real-world multicenter S-ICD cohort.<h4>Methods</h4>Patients implanted with an S-ICD from January ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(12):2050-2058]

Cited: 0 times

View full text PDF listing >>



Acute heart failure in elderly patients: a review of invasive and non-invasive management.

Gregorio Tersalvi, Alessio Gasperetti, Marco Schiavone, Jeroen Dauw, Cecilia Gobbi, Marialessia Denora, Joel Daniel Krul, Giacomo Maria Cioffi, Gianfranco Mitacchione, Giovanni B Forleo,

Acute heart failure (AHF) is a major cause of unplanned hospitalisations in the elderly and is associated with high mortality. Its prevalence has grown in the last years due to population aging and longer life expectancy of chronic heart failure patients. Although international societies have provided guidelines for the management ... Read more >>

J Geriatr Cardiol (Journal of geriatric cardiology : JGC)
[2021, 18(7):560-576]

Cited: 0 times

View full text PDF listing >>



Subcutaneous implantable cardioverter-defibrillator and defibrillation testing: A propensity-matched pilot study.

Giovanni B Forleo, Alessio Gasperetti, Alexander Breitenstein, Mikael Laredo, Marco Schiavone, Matteo Ziacchi, Julia Vogler, Danilo Ricciardi, Pietro Palmisano, Agostino Piro, Paolo Compagnucci, Xavier Waintraub, Gianfranco Mitacchione, Gianmarco Carrassa, Giulia Russo, Silvana De Bonis, Andrea Angeletti, Antonio Bisignani, Francesco Picarelli, Michela Casella, Edoardo Bressi, Giovanni Rovaris, Leonardo Calò, Luca Santini, Carlo Pignalberi, Carlo Lavalle, Maurizio Viecca, Ennio Pisanò, Iacopo Olivotto, Antonio Curnis, Antonio Dello Russo, Claudio Tondo, Charles J Love, Luigi Di Biase, Jan Steffel, Roland Tilz, Nicolas Badenco, Mauro Biffi,

<h4>Background</h4>To date, only a few comparisons between subcutaneous implantable cardioverter-defibrillator (S-ICD) patients undergoing and those not undergoing defibrillation testing (DT) at implantation (DT+ vs DT-) have been reported.<h4>Objective</h4>The purpose of this study was to compare long-term clinical outcomes of 2 propensity-matched cohorts of DT+ and DT- patients.<h4>Methods</h4>Among consecutive S-ICD patients ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(12):2072-2079]

Cited: 0 times

View full text PDF listing >>



Atrioventricular synchronous leadless pacemaker: state of art and broadened indications.

Gianfranco Mitacchione, Marco Schiavone, Alessio Gasperetti, Maurizio Viecca, Antonio Curnis, Giovanni B Forleo,

Leadless pacemakers (LLPMs) have become a major breakthrough in the management of bradyarrhythmia as an attractive alternative to the standard transvenous pacemakers (TV-PMs). Recently, the introduction of a second-generation LLPMs (Micra AV-MC1AVR1) has expanded pacing modes to obtain atrioventricular (AV) synchronous pacing, providing an interesting alternative in the actual scenario ... Read more >>

Rev Cardiovasc Med (Reviews in cardiovascular medicine)
[2021, 22(2):395-401]

Cited: 0 times

View full text PDF listing >>



Response to: COVID-19 re-infection. Vaccinated individuals as a potential source of transmission.

Marco Schiavone, Alessio Gasperetti, Gianfranco Mitacchione, Maurizio Viecca, Giovanni Battista Forleo,

Eur J Clin Invest (European journal of clinical investigation)
[2021, 51(6):e13544]

Cited: 2 times

View full text PDF listing >>



Effective nonapical left ventricular pacing with quadripolar leads for cardiac resynchronization therapy.

Giovanni B Forleo, Marco Schiavone, Domenico Della Rocca, Francesco Solimene, Vincenzo Schillaci, Gregorio Covino, Massimo Sassara, Gianluca Savarese, Stefano Donzelli, Sandra Badolati, Carmelo Gerosa, Carlo Lavalle, Alessio Gasperetti, Gianfranco Mitacchione, Mariolina Lovecchio, Sergio Valsecchi, Luca Santini,

<h4>Background</h4>Current guidelines recommend avoiding apical left ventricular (LV) pacing for cardiac resynchronization therapy (CRT).<h4>Aims</h4>We investigated the feasibility of nonapical pacing with the current quadripolar LV lead technology.<h4>Methods</h4>We analyzed consecutive patients who received CRT with an LV quadripolar lead. The post--implantation position of each electrode of the LV lead was designated ... Read more >>

Kardiol Pol (Kardiologia polska)
[2021, 79(4):442-448]

Cited: 0 times

View full text PDF listing >>



Targeting Bachmann's bundle in hybrid ablation for long-standing persistent atrial fibrillation: a proof of concept study.

Giuseppe De Martino, Giuseppe Nasso, Alessio Gasperetti, Marco Moscarelli, Carmine Mancusi, Giuseppe Della Ratta, Claudia Calvanese, Gianfranco Mitacchione, Raffaele Bonifazi, Nicola Di Bari, Enrico Vassallo, Marco Schiavone, Mario Gaudino, Giovanni B Forleo, Giuseppe Speziale,

<h4>Background</h4>Catheter-based or surgical procedures in patients with long-standing persistent atrial fibrillation (LSPAF) remain a challenge. As a result, different approaches including hybrid (surgical and endocardial) ablation have been developed. Bachmann's bundle (BB) is a mainly epicardial structure capable of sustaining arrhythmic reentry that could be involved in the development and ... Read more >>

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2021, :]

Cited: 3 times

View full text PDF listing >>



Prevalence and outcome of silent hypoxemia in COVID-19.

Mattia Busana, Alessio Gasperetti, Lorenzo Giosa, Giovanni B Forleo, Marco Schiavone, Gianfranco Mitacchione, Cecilia Bonino, Paolo Villa, Massimo Galli, Claudio Tondo, Ardan Saguner, Peter Steiger, Antonio Curnis, Antonio Dello Russo, Francesco Pugliese, Massimo Mancone, John J Marini, Luciano Gattinoni,

<h4>Background</h4>In the early stages of COVID-19 pneumonia, hypoxemia has been described in absence of dyspnea ("silent" or "happy" hypoxemia). Our aim was to report its prevalence and outcome in a series of hypoxemic patients upon Emergency Department admission.<h4>Methods</h4>In this retrospective observational cohort study we enrolled a study population consisting of ... Read more >>

Minerva Anestesiol (Minerva anestesiologica)
[2021, 87(3):325-333]

Cited: 8 times

View full text PDF listing >>



Impact of prior statin use on clinical outcomes in COVID-19 patients: data from tertiary referral hospitals during COVID-19 pandemic in Italy.

Gianfranco Mitacchione, Marco Schiavone, Antonio Curnis, Marcello Arca, Spinello Antinori, Alessio Gasperetti, Giosuè Mascioli, Paolo Severino, Federica Sabato, Maria M Caracciolo, Gianmarco Arabia, Laura D'Erasmo, Maurizio Viecca, Massimo Mancone, Massimo Galli, Giovanni B Forleo,

<h4>Background</h4>Epidemiological evidence suggests that anti-inflammatory and immunomodulatory properties of statins may reduce the risk of infections and infection-related complications.<h4>Objective</h4>We aimed to assess the impact of prior statin use on coronavirus disease (COVID-19) severity and mortality.<h4>Methods</h4>In this observational multicenter study, consecutive patients hospitalized for COVID-19 were enrolled. In-hospital mortality and severity ... Read more >>

J Clin Lipidol (Journal of clinical lipidology)
[2021, 15(1):68-78]

Cited: 17 times

View full text PDF listing >>



Clinical impact of defibrillation testing in a real-world S-ICD population: Data from the ELISIR registry.

Danilo Ricciardi, Matteo Ziacchi, Alessio Gasperetti, Marco Schiavone, Francesco Picarelli, Igor Diemberger, Luca Bontempi, Natale Di Belardino, Giovanni Bisignani, Silvia De Bonis, Gianfranco Mitacchione, Vito Calabrese, Carlo Lavalle, Agostino Piro, Carlo Pignalberi, Luca Santini, Francesco Grigioni, Claudio Tondo, Mauro Biffi, Giovanni Battista Forleo,

<h4>Background</h4>Current guidelines recommend defibrillation testing (DT) performance in patients with a subcutaneous implantable cardioverter defibrillator (S-ICD), theoretically to reduce the amount of ineffective shocks. DT, however, has been proven unnecessary in transvenous ICD and real-world data show a growing trend in avoidance of DT after S-ICD implantation.<h4>Methods</h4>All patients undergoing S-ICD ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2021, 32(2):468-476]

Cited: 0 times

View full text PDF listing >>



QT Interval Monitoring and Drugs Management During COVID-19 Pandemic.

Alessio Gasperetti, Marco Schiavone, Claudio Tondo, Gianfranco Mitacchione, Maurizio Viecca, Massimo Galli, Piercarlo Sarzi-Puttini, Giovanni B Forleo,

While facing potentially high morbidity from COVID-19 without known effective therapies, the off-label use of several non-specific drugs has been advocated, including re-purposed anti- viral (e.g., remdesivir or the lopinavir/ritonavir combination), biologic agents (e.g., tocilizumab), and antimalarial drugs such as chloroquine and hydroxychloroquine, in association with or without azithromycin. Data ... Read more >>

Curr Rev Clin Exp Pharmacol (Current reviews in clinical and experimental pharmacology)
[2021, 16(4):306-317]

Cited: 0 times

View full text PDF listing >>



Arrhythmic safety of hydroxychloroquine in COVID-19 patients from different clinical settings.

Alessio Gasperetti, Mauro Biffi, Firat Duru, Marco Schiavone, Matteo Ziacchi, Gianfranco Mitacchione, Carlo Lavalle, Ardan Saguner, Antonio Lanfranchi, Giacomo Casalini, Marco Tocci, Davide Fabbricatore, Francesca Salghetti, Marco Valerio Mariani, Mattia Busana, Alfonso Bellia, Chiara Beatrice Cogliati, Pierluigi Viale, Spinello Antinori, Massimo Galli, Nazzareno Galiè, Claudio Tondo, Giovanni Battista Forleo,

<h4>Aims</h4>The aim of the study was to describe ECG modifications and arrhythmic events in COVID-19 patients undergoing hydroxychloroquine (HCQ) therapy in different clinical settings.<h4>Methods and results</h4>COVID-19 patients at seven institutions receiving HCQ therapy from whom a baseline and at least one ECG at 48+ h were available were enrolled in ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2020, 22(12):1855-1863]

Cited: 9 times

View full text PDF listing >>



Redefining the Prognostic Value of High-Sensitivity Troponin in COVID-19 Patients: The Importance of Concomitant Coronary Artery Disease.

Marco Schiavone, Alessio Gasperetti, Massimo Mancone, Aaron V Kaplan, Cecilia Gobbi, Giosuè Mascioli, Mattia Busana, Ardan M Saguner, Gianfranco Mitacchione, Andrea Giacomelli, Gennaro Sardella, Maurizio Viecca, Firat Duru, Spinello Antinori, Stefano Carugo, Antonio L Bartorelli, Claudio Tondo, Massimo Galli, Francesco Fedele, Giovanni B Forleo,

<h4>Background</h4>Although studies assessing cardiovascular comorbidities and myocardial injury in Coronavirus disease 2019 (COVID-19) patients have been published, no reports focused on clinical outcomes of myocardial injury in patients with and without chronic coronary syndromes (CCS) are currently available.<h4>Methods</h4>In this study, consecutive COVID-19 patients admitted to four different institutions were screened ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(10):]

Cited: 11 times

View full text PDF listing >>



Neglected lead tip erosion: An unusual case of S-ICD inappropriate shock.

Gianfranco Mitacchione, Marco Schiavone, Alessio Gasperetti, Maurizio Viecca, Antonio Curnis, Giovanni B Forleo,

A 52-year-old man experienced a subcutaneous implantable cardioverter-defibrillator (S-ICD) inappropriate shock due to electrode tip decubitus. The device, implanted two years before with a three-incision technique, was extracted, and a new electrode was implanted along the contralateral parasternal line with a two-incision technique, in a one-stage procedure. One-year follow-up was ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2020, 31(12):3322-3325]

Cited: 0 times

View full text PDF listing >>



Oral anticoagulation and clinical outcomes in COVID-19: An Italian multicenter experience.

Marco Schiavone, Alessio Gasperetti, Massimo Mancone, Antonio Curnis, Giosuè Mascioli, Gianfranco Mitacchione, Mattia Busana, Federica Sabato, Cecilia Gobbi, Spinello Antinori, Massimo Galli, Giovanni Battista Forleo,

<h4>Background</h4>Since the body of evidence addressing the coagulation derangements caused by Coronavirus disease (COVID-19) has been constantly growing, we investigated whether pre-hospitalization oral anticoagulation (OAC) or in-hospital heparin treatment could have a protective role among COVID-19 patients.<h4>Method</h4>In this cohort study, consecutive COVID-19 patients admitted to four different Italian Institutions were ... Read more >>

Int J Cardiol (International journal of cardiology)
[2021, 323:276-280]

Cited: 15 times

View full text PDF listing >>



Ventricular tachycardia storm management in a COVID-19 patient: a case report.

Gianfranco Mitacchione, Marco Schiavone, Alessio Gasperetti, Giovanni B Forleo,

<h4>Background</h4>Coronavirus disease 2019 (COVID-19) has been associated with myocardial involvement. Among cardiovascular manifestations, cardiac arrhythmias seem to be fairly common, although no specifics are reported in the literature. An increased risk of malignant ventricular arrhythmias and electrical storm (ES) has to be considered.<h4>Case summary</h4>We describe a 68-year-old patient with a ... Read more >>

Eur Heart J Case Rep (European heart journal. Case reports)
[2020, 4(FI1):1-6]

Cited: 8 times

View full text PDF listing >>



Acute Coronary Syndromes and Covid-19: Exploring the Uncertainties.

Marco Schiavone, Cecilia Gobbi, Giuseppe Biondi-Zoccai, Fabrizio D'Ascenzo, Alberto Palazzuoli, Alessio Gasperetti, Gianfranco Mitacchione, Maurizio Viecca, Massimo Galli, Francesco Fedele, Massimo Mancone, Giovanni Battista Forleo,

Since an association between myocardial infarction (MI) and respiratory infections has been described for influenza viruses and other respiratory viral agents, understanding possible physiopathological links between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and acute coronary syndromes (ACS) is of the greatest importance. The initial data suggest an underestimation of ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(6):]

Cited: 27 times

View full text PDF listing >>



Transseptal catheterization of the native septum for atrial fibrillation ablation in presence of septal occluder device: a novel approach with real-time 3D transesophageal echocardiographic guidance.

Gianfranco Mitacchione, Antonio Curnis, Giovanni B Forleo,

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2020, 59(1):79-80]

Cited: 0 times

View full text PDF listing >>



First-in-human retrieval of chronically implanted Micra transcatheter pacing system.

Antonio Curnis, Manuel Cerini, Davide Mariggiò, Gianfranco Mitacchione, Daniele Giacopelli, Lorenza Inama, Luca Bontempi,

We report the first-in-human retrieval of a chronically implanted Micra transcatheter pacing system (TPS; Medtronic, Minneapolis, MN, USA). A 41-year-old woman suffering from third-degree atrioventricular block was successfully implanted with a TPS in the low septum of the right ventricle. After 29 months, due to an increased electrical threshold and ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2019, 42(7):1063-1065]

Cited: 0 times

View full text PDF listing >>



Efficacy and safety of cryoablation of para-Hisian and mid-septal accessory pathways using a specific protocol: single-center experience in consecutive patients.

Jacopo Marazzato, Giuseppe Fonte, Raffaella Marazzi, Lorenzo A Doni, Gianfranco Mitacchione, Manola Vilotta, Roberto De Ponti,

<h4>Purpose</h4>Radiofrequency (RF) catheter ablation of para-Hisian (P-H) and mid-septal (M-S) accessory pathways (APs) is a potentially harmful procedure due to their close location to the A-V node. Conversely, cryoablation (CA) appears safer in this setting. The aim of this study was to assess the efficacy and safety of CA of ... Read more >>

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2019, 55(1):47-54]

Cited: 2 times

View full text PDF listing >>



Management of a leadless pacemaker recall via extraction in a patient with a history of multiple previous device implants.

Antonio Curnis, Manuel Cerini, Lorenza Inama, Francesca Vassanelli, Davide Mariggiò, Francesca Salghetti, Gianfranco Mitacchione, Daniele Giacopelli, Luca Bontempi,

We describe a management strategy of a leadless pacemaker recall (LP) via extraction in a pacemaker-dependent patient with a history of multiple previous device implants. We performed a two-step procedure. First, we implanted a second LP in the right ventricle. Then, 3 days later for concerns about the stability of the ... Read more >>

J Electrocardiol (Journal of electrocardiology)
[2019, 53:5-7]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

1.2552 s