Full Text Journal Articles by
Author George Mitsiakos

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Meropenem vs standard of care for treatment of neonatal late onset sepsis (NeoMero1): A randomised controlled trial.

Irja Lutsar, Corine Chazallon, Ursula Trafojer, Vincent Meiffredy de Cabre, Cinzia Auriti, Chiara Bertaina, Francesca Ippolita Calo Carducci, Fuat Emre Canpolat, Susanna Esposito, Isabelle Fournier, Maarja Hallik, Paul T Heath, Mari-Liis Ilmoja, Elias Iosifidis, Jelena Kuznetsova, Laurence Meyer, Tuuli Metsvaht, George Mitsiakos, Zoi Dorothea Pana, Fabio Mosca, Lorenza Pugni, Emmanuel Roilides, Paolo Rossi, Kosmas Sarafidis, Laura Sanchez, Michael Sharland, Vytautas Usonis, Adilia Warris, Jean-Pierre Aboulker, Carlo Giaquinto, ,

BACKGROUND:The early use of broad-spectrum antibiotics remains the cornerstone for the treatment of neonatal late onset sepsis (LOS). However, which antibiotics should be used is still debatable, as relevant studies were conducted more than 20 years ago, recruited in single centres or countries, evaluated antibiotics not in clinical use anymore ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0229380]

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Meropenem vs standard of care for treatment of neonatal late onset sepsis (NeoMero1): a randomised controlled trial

Irja Lutsar, Corine Chazallon, Ursula Trafojer, Vincent Meiffredy de Cabre, Cinzia Auriti, Chiara Bertaina, Francesca Ippolita Calo Carducci, Fuat Emre Canpolat, Susanna Esposito, Isabelle Fournier, Maarja Hallik, Paul Heath Frcpch, Mari-Liis Ilmoja, Elias Iosifidis, Jelena Kuznetsova, Laurence Meyer, Tuuli Metsvaht, George Mitsiakos, Zoi Dorothea Pana, Fabio Mosca, Lorenza Pugni, Emmanuel Roilides, Paolo Rossi, Kosmas Sarafidis, Laura Sanchez, Michael Sharland, Vytautas Usonis, Adilia Warris, Jean-Pierre Aboulker, Carlo Giaquinto, ,

Abstract Background The early use of broad-spectrum antibiotics remains the cornerstone for the treatment of neonatal late onset sepsis (LOS). However, which antibiotics should be used is still debatable, as relevant studies were conducted more than 20 years ago, were single centre or country, insufficiently powered, evaluated antibiotics not in ... Read more >>

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Netherton Syndrome in a Neonate with Possible Growth Hormone Deficiency and Transient Hyperaldosteronism.

Chatziioannidis Ilias, Babatseva Evgenia, Patsatsi Aikaterini, Galli-Tsinopoulou Asimina, Sarri Constantina, Lithoxopoulou Maria, Mitsiakos George, Karagianni Paraskevi, Tsakalidis Christos, Mamuris Zissis, Nikolaidis Nikolaos,

Netherton syndrome, a rare autosomal recessive genetic disorder, is classified as an ichthyosiform syndrome. In this report we present the case of a neonate with erythroderma shortly after birth, accompanied by severe hypernatremia, recurrent infections, transient hyperaldosteronism, and signs of growth hormone (GH) deficiency. DNA molecular analysis in the SPINK5 ... Read more >>

Case Rep Pediatr (Case reports in pediatrics)
[2015, 2015:818961]

Cited: 1 time

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Corrigendum to "Netherton Syndrome in a Neonate with Possible Growth Hormone Deficiency and Transient Hyperaldosteronism".

Ilias Chatziioannidis, Evgenia Babatseva, Aikaterini Patsatsi, Asimina Galli-Tsinopoulou, Constantina Sarri, Maria Lithoxopoulou, George Mitsiakos, Paraskevi Karagianni, Christos Tsakalidis, Zissis Mamuris, Nikolaos Nikolaidis,

Case Rep Pediatr (Case reports in pediatrics)
[2015, 2015:328717]

Cited: 0 times

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Current management of late onset neonatal bacterial sepsis in five European countries.

Irja Lutsar, Corine Chazallon, Francesca Ippolita Cal├▓ Carducci, Ursula Trafojer, Ben Abdelkader, Vincent Meiffredy de Cabre, Susanna Esposito, Carlo Giaquinto, Paul T Heath, Mari-Liis Ilmoja, Aspasia Katragkou, Carine Lascoux, Tuuli Metsvaht, George Mitsiakos, Emmanuelle Netzer, Lorenza Pugni, Emmanuel Roilides, Yacine Saidi, Kosmas Sarafidis, Mike Sharland, Vytautas Usonis, Jean-Pierre Aboulker, ,

Late onset neonatal sepsis (LOS) has a high mortality and the optimal management is poorly defined. We aimed to evaluate new expert panel-derived criteria to define LOS and characterize the current management and antibiotic susceptibility of LOS-causing organisms in Europe. A prospective observational study enrolled infants aged 4 to 90 days ... Read more >>

Eur. J. Pediatr. (European journal of pediatrics)
[2014, 173(8):997-1004]

Cited: 15 times

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Are antenatal steroids beneficial to severely growth restricted fetuses?

George Mitsiakos, Lajos Kovacs, Apostolos Papageorgiou,

Antenatal steroids (AS) have been shown to enhance fetal maturation in preterms and to improve outcome. The aim of this study was to evaluate the efficacy of AS in premature severely intrauterine growth restricted infants. The electronic data of 149 inborn, single infants born 24 to 31 6/7 weeks of ... Read more >>

J. Matern. Fetal. Neonatal. Med. (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2013, 26(15):1496-1499]

Cited: 7 times

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A dedicated surveillance network for congenital toxoplasmosis in Greece, 2006-2009: assessment of the results.

Maria Aptouramani, Maria Theodoridou, George Syrogiannopoulos, Andreas Mentis, Vasiliki Papaevangelou, Katerina Gaitana, Alexandros Daponte, Christos Hadjichristodoulou, ,

BACKGROUND: Toxoplasmosis is caused by infection with the protozoan parasite Toxoplasma gondii. Acute infections in pregnant women may be transmitted to the fetus and cause severe illness. The purpose of this study was to establish a dedicated surveillance network (DSN) for congenital toxoplasmosis (CT) in Greece, in order to assess ... Read more >>

BMC Public Health (BMC public health)
[2012, 12:1019]

Cited: 2 times

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Haemostatic profile of healthy premature small for gestational age neonates.

George Mitsiakos, Evaggelia Giougi, Ilias Chatziioannidis, Paraskevi Karagianni, Emmanouil Papadakis, Christos Tsakalidis, Georgia Papaioannou, Pavlos Malindretos, Nikolaos Nikolaidis,

BACKGROUND: The pathogenetic profile of premature Small for Gestational Age (SGA) neonates is strongly related to their haemostatic equilibrium, which is inadequately understood. OBJECTIVE: To evaluate coagulation and fibrinolysis in premature SGA neonates before intervening with Vitamin K administration. STUDY DESIGN: We performed a comparison of coagulation, natural inhibitors and ... Read more >>

Thromb. Res. (Thrombosis research)
[2010, 126(2):103-106]

Cited: 6 times

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Early versus delayed minimal enteral feeding and risk for necrotizing enterocolitis in preterm growth-restricted infants with abnormal antenatal Doppler results.

Paraskevi Karagianni, Despina D Briana, George Mitsiakos, Anestis Elias, Theodoros Theodoridis, Elias Chatziioannidis, Maria Kyriakidou, Nikolaos Nikolaidis,

We studied the effect of early (< or = 5 days) versus delayed (> or = 6 days) initiation of minimal enteral feeding (MEF) on the incidence of necrotizing enterocolitis (NEC) and feeding intolerance in preterm infants with intrauterine growth restriction (IUGR) and abnormal antenatal Doppler results. We performed a ... Read more >>

Am J Perinatol (American journal of perinatology)
[2010, 27(5):367-373]

Cited: 23 times

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A case of Adams-Oliver syndrome following in vitro fertilization.

George Mitsiakos, Evaggelia Giougi, Christos Tsakalidis, Maria Kourti, Hlias Chatziionnidis, Paraskevi Karagianni, Efstratios M Kolibianakis, Nikolaos Nikolaidis,

Hum. Reprod. (Human reproduction (Oxford, England))
[2009, 24(6):1529-1530]

Cited: 1 time

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Haemostatic profile of full-term, healthy, small for gestational age neonates.

George Mitsiakos, Georgia Papaioannou, Emmanouil Papadakis, Elias Chatziioannidis, Evaggelia Giougi, Paraskevi Karagianni, Joanna Evdoridou, Pavlos Malindretos, Miranda Athanasiou, Fani Athanassiadou, Nikolaos Nikolaidis,

BACKGROUND: Small for Gestational Age (SGA) neonates often appear with haemostatic alterations, principally due to hepatic dysfunction that results from chronic intrauterine hypoxia. Polycythaemia and thrombocytopenia are common findings in this neonatal population. STUDY DESIGN: We performed a comparison of coagulation, natural inhibitors and fibrinolysis between SGA and Appropriate for ... Read more >>

Thromb. Res. (Thrombosis research)
[2009, 124(3):288-291]

Cited: 6 times

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Influence of smoking during pregnancy on haemostasis in healthy full term neonates.

George Mitsiakos, Evaggelia Giougi, Georgia Papaioannou, Paraskevi Karagianni, Emmanouil Papadakis, Nikolaos Nikolaidis,

BACKGROUND: Clinical and experimental researches have linked smoking to disturbances of coagulation and fibrinolysis. Several potential mechanisms are incriminated involving inflammation, fibrinogen synthesis and clotting factors. Based on the fact that the majority of tobacco components cross the placental barrier, the objective of our current study is to investigate the ... Read more >>

Thromb. Res. (Thrombosis research)
[2009, 123(3):476-481]

Cited: 0 times

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Is the use of rFVIIa safe and effective in bleeding neonates? A retrospective series of 8 cases.

George Mitsiakos, Georgia Papaioannou, Evagelia Giougi, Paraskevi Karagianni, Vassilia Garipidou, Nikolaos Nikolaidis,

Recombinant activated factor VII (rFVIIa), originally developed for the treatment of life-threatening bleeding in hemophilic patients with inhibitors to factors VIII or IX, has been increasingly used to control hemorrhage unresponsive to conventional treatment, in the absence of a defined coagulopathy or thrombocytopathy. To date, clinical experience of rFVIIa administration ... Read more >>

J. Pediatr. Hematol. Oncol. (Journal of pediatric hematology/oncology)
[2007, 29(3):145-150]

Cited: 17 times

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