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Author Ganesh Jevalikar

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Lack of Association of Baseline 25-Hydroxyvitamin D Levels and Cholecalciferol Treatment With Disease Severity and Mortality in Indian Patients Hospitalized for Covid-19

Ganesh Jevalikar, Ambrish Mithal, Anshu Singh, Rutuja Sharma, Khalid Farooqui, Shama Mahendru, Arun Dewan, Sandeep Budhiraja,

Vitamin D deficiency (VDD) owing to its immunomodulatory effects is believed to influence outcomes in COVID-19. We conducted a prospective, observational study of patients, hospitalized with COVID-19. Serum 25-OHD level < 20 ng/mL was considered VDD. Patients were classified as having mild and severe disease on basis of the WHO ... Read more >>

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High prevalence of diabetes and other comorbidities in hospitalized patients with COVID-19 in Delhi, India, and their association with outcomes.

Ambrish Mithal, Ganesh Jevalikar, Rutuja Sharma, Anshu Singh, Khalid J Farooqui, Shama Mahendru, Aishwarya Krishnamurthy, Arun Dewan, Sandeep Budhiraja,

<h4>Background and aims</h4>To study the prevalence and impact of diabetes mellitus and other comorbidities among hospitalized patients with COVID-19.<h4>Methods</h4>In a prospective, observational study including consecutive adults hospitalized with COVID-19, clinical outcomes and inflammatory markers were compared in those with and without diabetes. Participants were classified as having mild or severe ... Read more >>

Diabetes Metab Syndr (Diabetes & metabolic syndrome)
[2020, 15(1):169-175]

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Intestinal mucormycosis complicated by iliac artery aneurysm and ureteric rupture in a child with new-onset type 1 diabetes mellitus.

Ganesh Jevalikar, Rajni Sharma, Veena Raghunathan, Meera Luthra, Maninder S Dhaliwal, Vandana Jain, Ambrish Mithal,

J Paediatr Child Health (Journal of paediatrics and child health)
[2020, :]

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Cutaneous mucormycosis as a presenting feature of type 1 diabetes in a boy - case report and review of the literature.

Ganesh Jevalikar, Siddhnath Sudhanshu, Sanjay Mahendru, Smita Sarma, Khalid J Farooqui, Ambrish Mithal,

BACKGROUND:Mucormycosis is a potentially fatal complication of diabetes. The rhino-orbito-cerebral form is the most common presentation, however, rarely other types can also be seen. CASE PRESENTATION:We describe the case of a 4½ -year-old boy not previously known to be a diabetic who presented to the plastic surgery department for gangrene ... Read more >>

J Pediatr Endocrinol Metab (Journal of pediatric endocrinology & metabolism : JPEM)
[2018, 31(6):689-692]

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Effect of Empagliflozin on Liver Fat in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial (E-LIFT Trial).

Mohammad Shafi Kuchay, Sonal Krishan, Sunil Kumar Mishra, Khalid Jamal Farooqui, Manish Kumar Singh, Jasjeet Singh Wasir, Beena Bansal, Parjeet Kaur, Ganesh Jevalikar, Harmendeep Kaur Gill, Narendra Singh Choudhary, Ambrish Mithal,

OBJECTIVE:Sodium-glucose cotransporter 2 (SGLT-2) inhibitors have been shown to reduce liver fat in rodent models. Data regarding the effect of SGLT-2 inhibitors on human liver fat are scarce. This study examined the effect of empagliflozin (an SGLT-2 inhibitor) on liver fat in patients with type 2 diabetes and nonalcoholic fatty ... Read more >>

Diabetes Care (Diabetes care)
[2018, 41(8):1801-1808]

Cited: 55 times

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Acute Respiratory Distress Syndrome: A Rare Complication in Pediatric Diabetic Ketoacidosis.

Siddhnath Sudhanshu, Ganesh Jevalikar, Pravin K Das, Pramod K Singh, Eesh Bhatia, Vijayalakshmi Bhatia,

Cerebral edema (CE) and non cardiogenic pulmonary edema (acute respiratory distress syndrome, ARDS) are life-threatening complications of diabetic ketoacidosis (DKA). In contrast to CE complicating DKA, which is primarily reported in pediatric patients, ARDS is rarely described in this age group. Here, the authors present a child with DKA who ... Read more >>

Indian J Pediatr (Indian journal of pediatrics)
[2016, 83(5):463-465]

Cited: 4 times

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Childhood and Youth Onset Diabetes: A Single Centre Experience.

Ganesh Jevalikar, Chhavi Kohli, Beena Bansal, Sunil Kumar Mishra, Jasjeet Singh Wasir, Shweta Singh, Jasmine Kaur Ahuja, Parjeet Kaur, Khalid J Farooqui, Ambrish Mithal,

<h4>Objectives</h4>To identify proportion of various types of diabetes and differences between type 1 and type 2 diabetes in patients with youth onset diabetes (onset below 25 completed years of age). In addition, concurrent autoimmune diseases in type 1 diabetes were studied in a subset of patients.<h4>Methods</h4>A total of 577 patients ... Read more >>

Indian J Pediatr (Indian journal of pediatrics)
[2016, 83(8):792-798]

Cited: 1 time

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Efficacy and safety of a single monthly dose of cholecalciferol in healthy school children.

Mohammad Shafi Kuchay, Ganesh Sudhakar Jevalikar, Ambrish Mithal, Sunil Kumar Mishra, Navin Dang,

<h4>Background</h4>This study aimed to evaluate the efficacy and safety of a single monthly dose of cholecalciferol in healthy school children.<h4>Methods</h4>A total of 118 children of class VI of a residential school were selected to receive vitamin D supplementation in the form of oral cholecalciferol 60,000 IU monthly. Serum calcium and ... Read more >>

J Pediatr Endocrinol Metab (Journal of pediatric endocrinology & metabolism : JPEM)
[2016, 29(4):413-416]

Cited: 5 times

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Exogenous Cushing Syndrome due to Topical Clobetasone use for Diaper Rash.

Ganesh Jevalikar, Ojasvini Sharma,

Indian Pediatr (Indian pediatrics)
[2016, 53(1):76-77]

Cited: 0 times

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Turner syndrome patients with bicuspid aortic valves and renal malformations exhibit abnormal expression of X-linked inhibitor of apoptosis protein (XIAP).

Ganesh S Jevalikar, Margaret Zacharin, Mary White, Steven W Yau, Winnie Li, Charlotte Ijspeert, Vincenzo C Russo, George A Werther, Matthew A Sabin,

<h4>Objective</h4>We analyzed mRNA expression of X-linked inhibitor of apoptosis protein (XIAP) in patients with Turner syndrome (TS) and examined its association with phenotypic features.<h4>Subjects and methods</h4>XIAP mRNA expression levels were investigated in 98 patients with TS in total RNA extracted from blood leucocytes by real time quantitative polymerase chain reaction.<h4>Results</h4>Levels ... Read more >>

J Pediatr Endocrinol Metab (Journal of pediatric endocrinology & metabolism : JPEM)
[2015, 28(11-12):1203-1208]

Cited: 3 times

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Novel mutations of the arylsulphatase B (ARSB) gene in Indian patients with mucopolysaccharidosis type VI.

Anusha Uttarilli, Prajnya Ranganath, S Jamal Md Nurul Jain, C Krishna Prasad, Anupam Sinha, Ishwar C Verma, Shubha R Phadke, Ratna D Puri, Sumita Danda, Mamta N Muranjan, Ganesh Jevalikar, H A Nagarajaram, Ashwin B Dalal,

<h4>Background & objectives</h4>Mucopolysaccharidosis type VI (MPS VI) is a rare, autosomal recessive lysosomal storage disorder caused by deficient enzymatic activity of N-acetyl galactosamine-4-sulphatase resulting from mutations in the arylsulphatase B (ARSB) gene. The ARSB gene is located on chromosome 5q11-q13 and is composed of eight exons. More than hundred ARSB ... Read more >>

Indian J Med Res (The Indian journal of medical research)
[2015, 142(4):414-425]

Cited: 5 times

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Long-term outcomes of pediatric Graves' disease.

Ganesh Jevalikar, Julieta Solis, Margaret Zacharin,

<h4>Background</h4>Remission rates with antithyroid drugs (ATDs) in pediatric Graves' disease (GD) are low. Very few studies report long-term follow-up of GD especially into adulthood.<h4>Objectives</h4>We studied long-term outcomes of pediatric onset GD, including a follow-up into adulthood and factors associated with need for definitive therapy.<h4>Methods</h4>Sixty-five patients (57 females) with GD, with ... Read more >>

J Pediatr Endocrinol Metab (Journal of pediatric endocrinology & metabolism : JPEM)
[2014, 27(11-12):1131-1136]

Cited: 6 times

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From cerebral salt wasting to diabetes insipidus with adipsia: case report of a child with craniopharyngioma.

Veena Raghunathan, Maninder Singh Dhaliwal, Aditya Gupta, Ganesh Jevalikar,

<h4>Unlabelled</h4>Craniopharyngioma is associated with a wide and interesting variety of sodium states both by itself and following surgical resection. These are often challenging to diagnose, especially given their dynamic nature during the perioperative course. We present the case of a boy with craniopharyngioma who had hyponatremia due to cerebral salt ... Read more >>

J Pediatr Endocrinol Metab (Journal of pediatric endocrinology & metabolism : JPEM)
[2015, 28(3-4):323-326]

Cited: 2 times

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A guide to understanding the steroid pathway: new insights and diagnostic implications.

Ronda F Greaves, Ganesh Jevalikar, Jacqueline K Hewitt, Margaret R Zacharin,

Steroid analysis has always been complicated requiring a clear understanding of both the clinical and analytical aspects in order to accurately interpret results. The literature relating to this specialised area spans many decades and the intricacies of the steroid pathway have evolved with time. A number of key changes, including ... Read more >>

Clin Biochem (Clinical biochemistry)
[2014, 47(15):5-15]

Cited: 9 times

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Usage of pioglitazone at Medanta, the Medicity.

Ambrish Mithal, Parjeet Kaur, Beena Bansal, Sunil Kumar Mishra, Jasjeet S Wasir, Ganesh Jevalikar, Shama Mahendru,

Pioglitazone improves glycemic control by acting as an insulin sensitizer and is used in the management of Type 2 diabetes mellitus. Pioglitazone has recently been at the center of a controversy with regards to its safety. There is no clear consensus on how, when and in what dose the drug ... Read more >>

Indian J Endocrinol Metab (Indian journal of endocrinology and metabolism)
[2014, 18(1):111-112]

Cited: 5 times

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Rapidly evolving hypopituitarism in a boy with multiple autoimmune disorders.

Ganesh Jevalikar, Sze Choong Wong, Margaret Zacharin,

A 10-year-old boy with acute onset cranial diabetes insipidus and multiple autoimmune disorders had evolving panhypopituitarism, thought to be due to autoimmune hypophysitis. Over 18 months, a dramatic clinical course with progressive hypopituitarism and development of type 1 diabetes mellitus was evident. Serial brain imaging showed changes suggestive of germinoma. ... Read more >>

J Paediatr Child Health (Journal of paediatrics and child health)
[2013, 49(9):783-785]

Cited: 0 times

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Paradoxical euthyroid hormone profile in a case of Graves' disease with cardiac failure.

Ganesh Jevalikar, Priyanka Gupta, Vijayalakshmi Bhatia, Aditya Kapoor, Sanjay Gambhir,

Cardiac failure is an uncommon complication of juvenile hyperthyroidism. We describe an adolescent boy with Graves' disease who developed manifestations of heart failure while on antithyroid medications. There was no evidence of any underlying cardiac disease. He had paradoxical euthyroid hormone profile which rose to hyperthyroid range when the manifestations ... Read more >>

Int J Pediatr Endocrinol (International journal of pediatric endocrinology)
[2011, 2011:8]

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