Full Text Journal Articles by
Author Gabriel Ziegler

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Feasibility of Digital Memory Assessments in an Unsupervised and Remote Study Setting.

David Berron, Gabriel Ziegler, Paula Vieweg, Ornella Billette, Jeremie Güsten, Xenia Grande, Michael T Heneka, Anja Schneider, Stefan Teipel, Frank Jessen, Michael Wagner, Emrah Düzel,

Sensitive and frequent digital remote memory assessments via mobile devices hold the promise to facilitate the detection of cognitive impairment and decline. However, in order to be successful at scale, cognitive tests need to be applicable in unsupervised settings and confounding factors need to be understood. This study explored the ... Read more >>

Front Digit Health (Frontiers in digital health)
[2022, 4:892997]

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Amyloid pathology but not APOE ε4 status is permissive for tau-related hippocampal dysfunction.

Emrah Düzel, Gabriel Ziegler, David Berron, Anne Maass, Hartmut Schütze, Arturo Cardenas-Blanco, Wenzel Glanz, Coraline Metzger, Laura Dobisch, Martin Reuter, Annika Spottke, Frederic Brosseron, Klaus Fliessbach, Michael T Heneka, Christoph Laske, Oliver Peters, Josef Priller, Eike Jakob Spruth, Alfredo Ramirez, Oliver Speck, Anja Schneider, Stefan Teipel, Ingo Kilimann, Wiltfang Jens, Björn-Hendrik Schott, Lukas Preis, Daria Gref, Franziska Maier, Matthias H Munk, Nina Roy, Tomasso Ballarini, Renat Yakupov, John Dylan Haynes, Peter Dechent, Klaus Scheffler, Michael Wagner, Frank Jessen,

We investigated whether the impact of tau-pathology on memory performance and on hippocampal/medial temporal memory function in non-demented individuals depends on the presence of amyloid pathology, irrespective of diagnostic clinical stage. We conducted a cross-sectional analysis of the observational, multicentric DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE). Two hundred and ... Read more >>

Brain (Brain : a journal of neurology)
[2022, 145(4):1473-1485]

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