Full Text Journal Articles by
Author Franco Momoli

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Systemic quinolones and risk of acute liver failure III: A nested case-control study using a US electronic health records database.

Mohamed Kadry Taher, James A G Crispo, Yannick Fortin, Ryan Moog, Douglas McNair, Lise M Bjerre, Franco Momoli, Donald Mattison, Daniel Krewski,

<h4>Background and aim</h4>Quinolones are globally popular antibiotics with proven potency, broad coverage, and reasonable safety. However, some concerns were raised as to their possible association with acute liver failure (ALF). The aim of this study is to assess ALF risk within 30 days of receiving a systemically administered quinolone antibiotic, in ... Read more >>

J Gastroenterol Hepatol (Journal of gastroenterology and hepatology)
[2021, :]

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Associations between polysomnography measurements and postoperative adverse respiratory events in children with neuromuscular disease.

Haley Fishman, Jemila S Hamid, Nick Barrowman, Franco Momoli, Ian Maclusky, Sherri Lynne Katz,

<h4>Study objectives</h4>To determine if polysomnographic cardiorespiratory outcomes are associated with and could have the potential to predict the presence of postoperative adverse respiratory events in children with neuromuscular disease undergoing any surgical procedure.<h4>Methods</h4>A retrospective cohort study was conducted at a tertiary pediatric institution. The study population included individuals with neuromuscular ... Read more >>

J Clin Sleep Med (Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine)
[2021, 17(4):757-765]

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Clinical predictors of non-adherence to positive airway pressure therapy in children: a retrospective cohort study.

Henrietta Blinder, Franco Momoli, Stephen H Holland, Anna Blinder, Dhenuka Radhakrishnan, Sherri L Katz,

<h4>Study objectives</h4>Despite the importance of treating sleep-disordered breathing (SDB), positive airway pressure (PAP) adherence rates in children are low. Identifying readily-available predictors of non-adherence would enable the development of targeted interventions and supports, but literature is limited. Our objective was to identify baseline clinical predictors of six-month PAP therapy non-adherence ... Read more >>

J Clin Sleep Med (Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine)
[2021, :]

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Creating enriched training sets of eligible studies for large systematic reviews: the utility of PubMed's Best Match algorithm.

Margaret Sampson, Nassr Nama, Katharine O'Hearn, Kimmo Murto, Ahmed Nasr, Sherri L Katz, Gail Macartney, Franco Momoli, J Dayre McNally,

<h4>Introduction</h4>Solutions like crowd screening and machine learning can assist systematic reviewers with heavy screening burdens but require training sets containing a mix of eligible and ineligible studies. This study explores using PubMed's Best Match algorithm to create small training sets containing at least five relevant studies.<h4>Methods</h4>Six systematic reviews were examined ... Read more >>

Int J Technol Assess Health Care (International journal of technology assessment in health care)
[2020, 37:e7]

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Prevalence and the predictive performance of the dynamic CT-angiography spot sign in an observational cohort with intracerebral hemorrhage.

Dar Dowlatshahi, Hee Sahng Chung, Michael Reaume, Matthew J Hogan, Dylan Blacquiere, Grant Stotts, Michel Shamy, Franco Momoli, Richard Aviv, Andrew M Demchuk, Santanu Chakraborty,

The CT-angiography (CTA) spot sign is a predictor of hematoma expansion (HE). We have previously reported on the use of dynamic CTA (dCTA) to detect spot sign, and to study its formation over the acquisition period. In this study, we report the frequency of dCTA spot sign in acute intracerebral ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(47):e23278]

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The REACH registration process: A case study of metallic aluminium, aluminium oxide and aluminium hydroxide.

Calvin C Willhite, Nataliya A Karyakina, Eirik Nordheim, Ian Arnold, Vic Armstrong, Franco Momoli, Natalia S Shilnikova, Nagarajkumar Yenugadhati, Daniel Krewski,

The European Union's REACH Regulation requires determination of potential health and environmental effects of chemicals in commerce. The present case study examines the application of REACH guidance for health hazard assessments of three high production volume (HPV) aluminium (Al) substances: metallic aluminium, aluminium oxide, and aluminium hydroxide. Among the potential ... Read more >>

Neurotoxicology (Neurotoxicology)
[2021, 83:166-178]

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Melatonin to prevent delirium in patients with advanced cancer: a double blind, parallel, randomized, controlled, feasibility trial.

Peter G Lawlor, Marie T McNamara-Kilian, Alistair R MacDonald, Franco Momoli, Sallyanne Tierney, Nathalie Lacaze-Masmonteil, Monidipa Dasgupta, Meera Agar, Jose L Pereira, David C Currow, Shirley H Bush,

<h4>Background</h4>Delirium is highly problematic in palliative care (PC). Preliminary data indicate a potential role for melatonin to prevent delirium, but no randomized controlled trials (RCTs) are reported in PC.<h4>Methods</h4>Patients aged ≥18 years, with advanced cancer, admitted to an inpatient Palliative Care Unit (PCU), having a Palliative Performance Scale rating ≥ 30%, and for ... Read more >>

BMC Palliat Care (BMC palliative care)
[2020, 19(1):163]

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Aortic Valve Intervention During Aortic Root Surgery in Children: A Systematic Review.

Maria Rodriguez, Anahita Malvea, Dayre McNally, Vid Bijelic, Ming Guo, Franco Momoli, Munir Boodhwani,

<h4>Background</h4>Pediatric aortic root dilatation is a life-threatening condition that lacks guidelines for surgical management. We aimed to analyze the data on aortic valve interventions during root surgery to guide decision-making.<h4>Methods</h4>A search was performed of MEDLINE, Embase, CENTRAL, ClinicalTrials.gov, and WHO ICTRP. Citations were screened in duplicate and independently to identify ... Read more >>

World J Pediatr Congenit Heart Surg (World journal for pediatric & congenital heart surgery)
[2020, 11(5):611-618]

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Risk of Adverse Cardiovascular Events Following a Myocardial Infarction in Patients Receiving Combined Clopidogrel and Proton Pump Inhibitor Treatment: A Nested Case-Control Study.

Nawal Farhat, Nicholas Birkett, Nisrine Haddad, Yannick Fortin, Franco Momoli, Shi Wu Wen, Andreas Wielgosz, Doug S McNair, Donald R Mattison, Daniel Krewski,

BACKGROUND:The clinical implications of potential interactions between proton pump inhibitors (PPIs) and clopidogrel have been debated for over a decade. OBJECTIVE:We assessed the association between combined clopidogrel-PPI treatment and the risk of recurrent myocardial infarction (MI) and three secondary outcomes. PATIENTS AND METHODS:A nested case-control study was conducted within Cerner ... Read more >>

Drugs Real World Outcomes (Drugs - real world outcomes)
[2020, 7(3):191-203]

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Mental Health Service Use in Depressed Military Personnel: A Systematic Review.

François L Thériault, William Gardner, Franco Momoli, Bryan G Garber, Mila Kingsbury, Zahra Clayborne, Daniel Y Cousineau-Short, Hugues Sampasa-Kanyinga, Hannah Landry, Ian Colman,

<h4>Introduction</h4>Major depression is a leading cause of morbidity in military personnel and an important impediment to operational readiness in military organizations. Although treatment options are available, a large proportion of individuals with depression do not access mental health services. Quantifying and closing this treatment gap is a public health priority. ... Read more >>

Mil Med (Military medicine)
[2020, 185(7-8):e1255-e1262]

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Hearing loss prevalence and hearing health among school-aged children in the Canadian Arctic.

Elizabeth M Fitzpatrick, Lynne McCurdy, JoAnne Whittingham, Ryan Rourke, Flora Nassrallah, Viviane Grandpierre, Franco Momoli, Vid Bijelic,

Objective: Hearing loss is an important health concern in Canada's Arctic. The objective of this research was to provide information on the prevalence of childhood hearing loss in Nunavut.Design: This cross-sectional study involved comprehensive audiologic assessments of school-aged children in six communities to determine overall and community-specific prevalence of hearing ... Read more >>

Int J Audiol (International journal of audiology)
[2020, :1-11]

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Clinical presentation of young people (10-24 years old) with brain tumors: results from the international MOBI-Kids study.

Angela Zumel-Marne, Michael Kundi, Gemma Castaño-Vinyals, Juan Alguacil, Eleni Th Petridou, Marios K Georgakis, Maria Morales-Suárez-Varela, Siegal Sadetzki, Sara Piro, Rajini Nagrani, Graziella Filippini, Hans-Peter Hutter, Rajesh Dikshit, Adelheid Woehrer, Milena Maule, Tobias Weinmann, Daniel Krewski, Andrea T Mannetje, Franco Momoli, Brigitte Lacour, Stefano Mattioli, John J Spinelli, Paul Ritvo, Thomas Remen, Noriko Kojimahara, Amanda Eng, Angela Thurston, Hyungryul Lim, Mina Ha, Naohito Yamaguchi, Charmaine Mohipp, Evdoxia Bouka, Chelsea Eastman, Roel Vermeulen, Hans Kromhout, Elisabeth Cardis,

<h4>Introduction</h4>We used data from MOBI-Kids, a 14-country international collaborative case-control study of brain tumors (BTs), to study clinical characteristics of the tumors in older children (10 years or older), adolescents and young adults (up to the age of 24).<h4>Methods</h4>Information from clinical records was obtained for 899 BT cases, including signs and ... Read more >>

J Neurooncol (Journal of neuro-oncology)
[2020, 147(2):427-440]

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Exposure to Medical Radiation during Fetal Life, Childhood and Adolescence and Risk of Brain Tumor in Young Age: Results from The MOBI-Kids Case-Control Study.

Elisa Pasqual, Gemma Castaño-Vinyals, Isabelle Thierry-Chef, Noriko Kojimahara, Malcolm R Sim, Michael Kundi, Daniel Krewski, Franco Momoli, Brigitte Lacour, Thomas Remen, Katja Radon, Tobias Weinmann, Eleni Petridou, Maria Moschovi, Rajesh Dikshit, Siegal Sadetski, Milena Maule, Mariangela Farinotti, Mina Ha, Andrea 't Mannetje, Juan Alguacil, Nuria Aragonés, Roel Vermeulen, Hans Kromhout, Elisabeth Cardis,

BACKGROUND:We explored the association between ionizing radiation (IR) from pre-natal and post-natal radio-diagnostic procedures and brain cancer risk within the MOBI-kids study. METHODS:MOBI-kids is an international (Australia, Austria, Canada, France, Germany, Greece, India, Israel, Italy, Japan, Korea, New Zealand, Spain, The Netherlands) case-control study including 899 brain tumor (645 neuroepithelial) ... Read more >>

Neuroepidemiology (Neuroepidemiology)
[2020, 54(4):343-355]

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Neonatal necrotizing enterocolitis: a case series examining clinical diagnosis with discrepant versus concordant autopsy results.

Sarah L Lawrence, David Grynspan, Monica Chan, Julie Hurteau, C L Elizabeth Nizalik, Franco Momoli, Emanuela Ferretti,

<h4>Objective</h4>The objective of this study is to determine whether rapidity of death in necrotizing enterocolitis (NEC) increased odds of discordance between clinical and pathological diagnosis.<h4>Study design</h4>Retrospective case-series study including preterm infants admitted to the NICU.<h4>Results</h4>Twenty-two infants met the selection criteria. Gross pathologic evidence of NEC was present in 1/6 cases ... Read more >>

J Perinatol (Journal of perinatology : official journal of the California Perinatal Association)
[2020, 40(6):928-934]

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Predictors of adherence to positive airway pressure therapy in children: a systematic review and meta-analysis.

Henrietta Blinder, Franco Momoli, Julia Bokhaut, Vanessa Bacal, Reuben Goldberg, Dhenuka Radhakrishnan, Sherri L Katz,

<h4>Background</h4>While positive airway pressure (PAP) is effective for treating sleep-disordered breathing (SDB) in children, adherence is poor. Studies evaluating predictors of PAP adherence have inconsistent findings, and no rigorous reviews have been conducted. This systematic review aims to summarize the literature on predictors of PAP therapy adherence in children.<h4>Methods</h4>Studies evaluating ... Read more >>

Sleep Med (Sleep medicine)
[2020, 69:19-33]

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Predictors of postoperative respiratory complications in children undergoing adenotonsillectomy.

Sherri L Katz, Andrea Monsour, Nicholas Barrowman, Lynda Hoey, Matthew Bromwich, Franco Momoli, Theodora Chan, Reuben Goldberg, Abhilasha Patel, Li Yin, Kimmo Murto,

<h4>Study objectives</h4>Obstructive sleep apnea (OSA) is commonly treated with adenotonsillectomy (AT), bringing risk of perioperative respiratory adverse events (PRAEs). We aimed to concurrently identify clinical and polysomnographic predictors of PRAEs in children undergoing AT.<h4>Methods</h4>Retrospective study of children undergoing AT at a tertiary-care pediatric hospital, with prior in-hospital polysomnography, January 2010 ... Read more >>

J Clin Sleep Med (Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine)
[2020, 16(1):41-48]

Cited: 2 times

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A randomized controlled trial comparing subscapularis tenotomy with peel in anatomic shoulder arthroplasty.

Peter Lapner, J Whitcomb Pollock, Tinghua Zhang, Sara Ruggiero, Franco Momoli, Adnan Sheikh, George S Athwal,

BACKGROUND:Controversy exists regarding the optimal technique of subscapularis tendon mobilization during anatomic shoulder arthroplasty. The purpose of this prospective, randomized, double-blind study was to compare internal rotation strength in the belly-press position and functional outcomes between the subscapularis tenotomy and subscapularis peel approaches during shoulder arthroplasty. METHODS:Patients undergoing anatomic shoulder ... Read more >>

J Shoulder Elbow Surg (Journal of shoulder and elbow surgery)
[2020, 29(2):225-234]

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The development of respondent-driven sampling (RDS) inference: A systematic review of the population mean and variance estimates.

Kahina Abdesselam, Ashton Verdery, Linda Pelude, Parminder Dhami, Franco Momoli, Ann M Jolly,

BACKGROUND:Respondent-driven sampling (RDS) is a successful data collection method used in hard-to-reach populations, like those experiencing or at high risk of drug dependence. Since its introduction in 1997, identifying appropriate methods for estimating population means and sampling variances has been challenging and numerous approaches have been developed for making inferences ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2020, 206:107702]

Cited: 1 time

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High Rate of Medical Emergency Team Activation in Children with Tracheostomy.

Brianna L McKelvie, Anna-Theresa Lobos, Jason Chan, Franco Momoli, James Dayre McNally,

Pediatric in-patients with tracheostomy (PIT) are at high risk for clinical deterioration. Medical emergency teams (MET) have been developed to identify high-risk patients. This study compared MET activation rates between PITs and the general ward population. This was a retrospective cohort study conducted at a tertiary pediatric hospital. The primary ... Read more >>

J Pediatr Intensive Care (Journal of pediatric intensive care)
[2020, 9(1):27-33]

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A Retrospective Case-Control Study to Identify Predictors of Unplanned Admission to Pediatric Intensive Care Within 24 Hours of Hospitalization.

Kristina Krmpotic, Anna-Theresa Lobos, Jason Chan, Christina Toppozini, Candice McGahern, Franco Momoli, Amy C Plint,

<h4>Objectives</h4>To identify the clinical findings available at the time of hospitalization from the emergency department that are associated with deterioration within 24 hours.<h4>Design</h4>A retrospective case-control study.<h4>Setting</h4>A pediatric hospital in Ottawa, ON, Canada.<h4>Patients</h4>Children less than 18 years old who were hospitalized via the emergency department between January 1, 2008, and December ... Read more >>

Pediatr Crit Care Med (Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies)
[2019, 20(7):e293-e300]

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Obstructive sleep apnea and hypertension in pediatric chronic kidney disease.

Anne Tsampalieros, Henrietta Blinder, Lynda Hoey, Franco Momoli, Nicholas Barrowman, Janusz Feber, Naomi Spitale, Sherri Lynne Katz,

BACKGROUND:Children with chronic kidney disease (CKD) are at risk for obstructive sleep apnea (OSA) and hypertension. The objectives of this study were to explore associations between OSA severity using the apnea-hypopnea-index(AHI) and obstructive apnea-hypopnea-index(OAHI) on polysomnography (PSG), OSA symptoms, and measures of hypertension in children with CKD. METHODS:One-night in-laboratory PSGs ... Read more >>

Pediatr Nephrol (Pediatric nephrology (Berlin, Germany))
[2019, 34(11):2361-2370]

Cited: 2 times

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The incidence and prevalence of delirium across palliative care settings: A systematic review.

Christine L Watt, Franco Momoli, Mohammed T Ansari, Lindsey Sikora, Shirley H Bush, Annmarie Hosie, Monisha Kabir, Erin Rosenberg, Salmaan Kanji, Peter G Lawlor,

<h4>Background</h4>Delirium is a common and distressing neurocognitive condition that frequently affects patients in palliative care settings and is often underdiagnosed.<h4>Aim</h4>Expanding on a 2013 review, this systematic review examines the incidence and prevalence of delirium across all palliative care settings.<h4>Design</h4>This systematic review and meta-analyses were prospectively registered with PROSPERO and included ... Read more >>

Palliat Med (Palliative medicine)
[2019, 33(8):865-877]

Cited: 5 times

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Systematic review and meta-analysis of adverse cardiovascular events associated with proton pump inhibitors used alone or in combination with antiplatelet agents.

Nawal Farhat, Yannick Fortin, Nisrine Haddad, Nicholas Birkett, Donald R Mattison, Franco Momoli, Shi Wu Wen, Daniel Krewski,

The potential association between major adverse cardiovascular events (MACE) and concomitant treatment with proton pump inhibitors (PPIs) and clopidogrel has been debated since 2009. Recent reports, however, suggest that PPIs may increase the risk of MACE independently of clopidogrel. This review evaluates epidemiological findings relevant to the association between PPIs, ... Read more >>

Crit Rev Toxicol (Critical reviews in toxicology)
[2019, 49(3):215-261]

Cited: 1 time

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Social determinants of health among residential areas with a high tuberculosis incidence in a remote Inuit community.

Elaine Kilabuk, Franco Momoli, Ranjeeta Mallick, Deborah Van Dyk, Christopher Pease, Alice Zwerling, Sharon Edmunds Potvin, Gonzalo G Alvarez,

BACKGROUND:Tuberculosis (TB) remains a significant health burden among Inuit in Canada. Social determinants of health (SDH) play a key role in TB infection, disease and ongoing transmission in this population. The objective of this research was to estimate the prevalence of social determinants of Inuit health as they relate to ... Read more >>

J Epidemiol Community Health (Journal of epidemiology and community health)
[2019, 73(5):401-406]

Cited: 2 times

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Nonparticipation Selection Bias in the MOBI-Kids Study.

Michelle C Turner, Esther Gracia-Lavedan, Franco Momoli, Chelsea E Langer, Gemma Castaño-Vinyals, Michael Kundi, Milena Maule, Franco Merletti, Siegal Sadetzki, Roel Vermeulen, Alex Albert, Juan Alguacil, Nuria Aragones, Francesc Badia, Revital Bruchim, Gema Carretero, Noriko Kojimahara, Brigitte Lacour, Maria Morales-Suarez-Varela, Katja Radon, Thomas Remen, Tobias Weinmann, Naohito Yamaguchi, Elisabeth Cardis,

<h4>Background</h4>MOBI-Kids is a 14-country case-control study designed to investigate the potential effects of electromagnetic field exposure from mobile telecommunications devices on brain tumor risk in children and young adults conducted from 2010 to 2016. This work describes differences in cellular telephone use and personal characteristics among interviewed participants and refusers ... Read more >>

Epidemiology (Epidemiology (Cambridge, Mass.))
[2019, 30(1):145-153]

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