Full Text Journal Articles by
Author Francesco Fanfani

Advertisement

Find full text journal articles






Laparoscopic vs. robotic-assisted laparoscopy in endometrial cancer staging: large retrospective single-institution study.

Emanuele Perrone, Ilaria Capasso, Tina Pasciuto, Alessandro Gioè, Salvatore Gueli Alletti, Stefano Restaino, Giovanni Scambia, Francesco Fanfani,

<h4>Objective</h4>The aim of this study is to analyze and draw the potential differences between the robotic-assisted surgery (RS) and the laparoscopy (LPS) in endometrial cancer staging.<h4>Methods</h4>In this single-institution retrospective study we enrolled 1,221 consecutive clinical stage I-III endometrial cancer patients undergone minimally invasive surgical staging. We compared patients treated by ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(3):e45]

Cited: 0 times

View full text PDF listing >>



Validation of tumour-free distance as novel prognostic marker in early-stage cervical cancer: a retrospective, single-centre, cohort study.

Nicolò Bizzarri, Luigi Pedone Anchora, Gian Franco Zannoni, Vittoria Carbone, Matteo Bruno, Camilla Fedele, Valerio Gallotta, Vito Chiantera, Giacomo Avesani, Benedetta Gui, Francesco Fanfani, Anna Fagotti, Giovanni Scambia, Gabriella Ferrandina,

<h4>Background</h4>The aim of the present study was to assess the prognostic value of tumour-free distance (TFD), defined as the minimum distance of uninvolved stroma between the tumour and peri-cervical stromal ring, in early-stage cervical cancer.<h4>Methods</h4>Patients with pathologic FIGO 2009 stage IA1-IIA2 cervical cancer, treated by primary radical surgical treatment between ... Read more >>

Br J Cancer (British journal of cancer)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Mismatch repair-deficiency specifically predicts recurrence of atypical endometrial hyperplasia and early endometrial carcinoma after conservative treatment: A multi-center study.

Antonio Raffone, Ursula Catena, Antonio Travaglino, Valeria Masciullo, Saveria Spadola, Luigi Della Corte, Alessia Piermattei, Luigi Insabato, Gian Franco Zannoni, Giovanni Scambia, Fulvio Zullo, Giuseppe Bifulco, Francesco Fanfani, Attilio Di Spiezio Sardo,

<h4>Objective</h4>Deficient expression of mismatch repair proteins (MMR) has been suggested to be a predictor of resistance of atypical endometrial hyperplasia (AEH) and early endometrial carcinoma (EEC) to conservative treatment.<h4>Aims</h4>To assess the predictive value of MMR immunohistochemistry in patients conservatively treated for AEH and EEC, and to calculate its predictive accuracy.<h4>Materials ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Oncologic and obstetric outcomes after simple conization for fertility-sparing surgery in FIGO 2018 stage IB1 cervical cancer.

Francesco Fanfani, Luigi Pedone Anchora, Giampaolo Di Martino, Nicolò Bizzarri, Maria Letizia Di Meo, Vittoria Carbone, Mariachiara Paderno, Camilla Fedele, Cristiana Paniga, Anna Fagotti, Fabio Landoni, Giovanni Scambia, Alessandro Buda,

<h4>Objective</h4>Conization/simple trachelectomy is feasible in patients with early-stage cervical cancer. Retrospective data suggest that conization with negative lymph nodes could be a safe option for these patients. This study aims to provide oncologic and obstetric outcomes of a large series of patients with 2018 International Federation of Gynecology and Obstetrics ... Read more >>

Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2021, 31(3):452-456]

Cited: 0 times

View full text PDF listing >>



In search for biomarkers and potential drug targets for uterine serous endometrial cancer.

Giorgia Dinoi, Andrea Mariani, Enrica Martinelli, Alessandra Ciucci, Gian Franco Zannoni, Amy L Weaver, Gary L Keeney, George Vasmatzis, Panos Z Anastasiadis, Francesco Fanfani, Giovanni Scambia, Daniela Gallo,

<h4>Objective</h4>Serous endometrial cancer (USC) is a challenging malignancy associated with metastasis, recurrence and poor outcome. To identify clinically relevant prognostic biomarkers, we focused on a panel of proteins selected after a comprehensive literature review, for tumour profiling of a homogeneous cohort of USC patients.<h4>Methods</h4>Protein levels and localization were assessed by ... Read more >>

J Cancer Res Clin Oncol (Journal of cancer research and clinical oncology)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Protective Role of Conization Before Radical Hysterectomy in Early-Stage Cervical Cancer: A Propensity-Score Matching Study.

Nicolò Bizzarri, Luigi Pedone Anchora, Ali Kucukmetin, Nithya Ratnavelu, Porfyrios Korompelis, Vittoria Carbone, Camilla Fedele, Matteo Bruno, Giuseppe Vizzielli, Valerio Gallotta, Rosa De Vincenzo, Vito Chiantera, Anna Fagotti, Francesco Fanfani, Gabriella Ferrandina, Giovanni Scambia,

<h4>Purpose</h4>The purpose of this study was to assess the prognostic role and the perioperative outcomes of conization performed before radical hysterectomy in early-stage cervical carcinoma.<h4>Methods</h4>This multicenter, retrospective observational cohort study included patients with FIGO 2009 stage IB1 cervical carcinoma treated with radical hysterectomy between June 2004 and June 2019. Patients were ... Read more >>

Ann Surg Oncol (Annals of surgical oncology)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Prognostic impact of hysteroscopic resection of endometrial atypical hyperplasia-endometrioid intraepithelial neoplasia and early-stage cancer in combination with megestrol acetate.

Valeria Masciullo, Nausica Trivellizzi, Gianfranco Zannoni, Ursula Catena, Rossana Moroni, Francesco Fanfani, Giovanni Scambia,

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2021, 224(4):408-410]

Cited: 0 times

View full text PDF listing >>



Substantial lymph-vascular space invasion (LVSI) as predictor of distant relapse and poor prognosis in low-risk early-stage endometrial cancer.

Lucia Tortorella, Stefano Restaino, Gian Franco Zannoni, Giuseppe Vizzielli, Vito Chiantera, Serena Cappuccio, Alessandro Gioè, Eleonora La Fera, Giorgia Dinoi, Giuseppe Angelico, Giovanni Scambia, Francesco Fanfani,

<h4>Objective</h4>The aim of this study is to analyze the prognostic role of lymph-vascular space invasion (LVSI), evaluated in a semi-quantitative fashion on prognosis of early stage, low risk endometrial cancer (EC).<h4>Methods</h4>We enrolled patients who underwent surgery for endometrial cancer between 2003 and 2018 in two referral cancer center. All patients ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e11]

Cited: 1 time

View full text PDF listing >>



Update on new imaging technologies in sentinel node detection.

Silvia Pelligra, Giuseppe Scaletta, Stefano Cianci, Salvatore Gueli Alletti, Stefano Restaino, Anna Fagotti, Giovanni Scambia, Francesco Fanfani,

In most cancers, lymph node status is the most critical factor impacting the evolution of the disease and the overall survival. Identifying potential nodal metastasis allows the oncologist to adjust the stage and, consequently, the patient's treatment. For this reason, a precise evaluation of the regional nodes is mandatory. In ... Read more >>

Minerva Ginecol (Minerva ginecologica)
[2020, 72(6):404-412]

Cited: 0 times

View full text PDF listing >>



Peritoneal HPV-DNA test in cervical cancer (PIONEER study): A proof of concept.

Nicolò Bizzarri, Luigi Pedone Anchora, Paola Cattani, Rosa De Vincenzo, Simona Marchetti, Carmine Conte, Vito Chiantera, Valerio Gallotta, Salvatore Gueli Alletti, Giuseppe Vizzielli, Barbara Costantini, Anna Fagotti, Francesco Fanfani, Giovanni Scambia, Gabriella Ferrandina,

The aim of this study was to investigate the prevalence of peritoneal human papillomavirus (HPV) infection in different clinical cervical cancer (CC) settings, and its association with potential clinical and/or histological factors. This is a single-center, prospective, observational study. Consecutive patients with newly diagnosed or recurrent/persistent CC, between March 2019 ... Read more >>

Int J Cancer (International journal of cancer)
[2021, 148(5):1197-1207]

Cited: 0 times

View full text PDF listing >>



Correction to: The impact of low-volume metastasis on disease-free survival of women with early-stage cervical cancer.

Alessandro Buda, Jvan Casarin, Michael Mueller, Francesco Fanfani, Ignacio Zapardiel, Liliana Mereu, Andrea Puppo, Elena De Ponti, Marco Adorni, Debora Ferrari, Maria Luisa Gasparri, Fabio Ghezzi, Giovanni Scambia, Andrea Papadia,

In the original article, the name of the second author is incorrect. ... Read more >>

J Cancer Res Clin Oncol (Journal of cancer research and clinical oncology)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Semiquantitative evaluation of lymph-vascular space invasion in patients affected by endometrial cancer: Prognostic and clinical implications.

Stefano Restaino, Lucia Tortorella, Giorgia Dinoi, Gian-Franco Zannoni, Alessandro Baroni, Ilaria Capasso, Ettore Distefano, Giulio Sozzi, Vito Chiantera, Giovanni Scambia, Francesco Fanfani,

<h4>Objectives</h4>The interpretation of lymph-vascular space invasion (LVSI) is usually qualitative, as presence or absence. The aim of this study is to investigate the prognostic role of LVSI in patients affected by endometrial cancer, when evaluated with a semiquantitative analysis.<h4>Methods</h4>This retrospective multicentre study enrolled patients who received a histologically confirmed diagnosis ... Read more >>

Eur J Cancer (European journal of cancer (Oxford, England : 1990))
[2021, 142:29-37]

Cited: 0 times

View full text PDF listing >>



Neoadjuvant chemotherapy followed by conization in stage IB2-IIA1 cervical cancer larger than 2 cm: a pilot study.

Rosa de Vincenzo, Caterina Ricci, Francesco Fanfani, Benedetta Gui, Valerio Gallotta, Anna Fagotti, Gabriella Ferrandina, Giovanni Scambia,

<h4>Objective</h4>To evaluate feasibility of neoadjuvant chemotherapy (NACT) followed by cold-knife conization (CKC) in patients with 2018 FIGO stage IB2-IIA1 cervical cancer who desired to maintain fertility.<h4>Design</h4>Pilot study of conization after chemotherapy in stage IB2-IIA1 >2 cm cervical cancer.<h4>Setting</h4>University hospital.<h4>Patient(s)</h4>From 2014 to 2018, 25 patients, <40 years of age, were enrolled.<h4>Interventions(s)</h4>After ... Read more >>

Fertil Steril (Fertility and sterility)
[2021, 115(1):148-156]

Cited: 0 times

View full text PDF listing >>



The impact of low-volume metastasis on disease-free survival of women with early-stage cervical cancer.

Alessandro Buda, Jvan Casarin, Michael Mueller, Francesco Fanfani, Ignacio Zapardiel, Liliana Mereu, Andrea Puppo, Elena De Ponti, Marco Adorni, Debora Ferrari, Maria Luisa Gasparri, Fabio Ghezzi, Giovanni Scambia, Andrea Papadia,

<h4>Purpose</h4>We aimed to assess the impact of low-volume metastasis (micrometastasis and isolated tumor cells) on disease-free survival (DFS) of women with early-stage cervical cancer.<h4>Methods</h4>Women with clinically suspected stage 1A-IB2 (FIGO 2018 classification) disease who underwent retroperitoneal nodal staging between October 2010 and April 2018, were retrospectively analyzed. The group of ... Read more >>

J Cancer Res Clin Oncol (Journal of cancer research and clinical oncology)
[2020, :]

Cited: 1 time

View full text PDF listing >>



Randomized trial of primary debulking surgery versus neoadjuvant chemotherapy for advanced epithelial ovarian cancer (SCORPION-NCT01461850).

Anna Fagotti, Maria Gabriella Ferrandina, Giuseppe Vizzielli, Tina Pasciuto, Francesco Fanfani, Valerio Gallotta, Pasquale Alessandro Margariti, Vito Chiantera, Barbara Costantini, Salvatore Gueli Alletti, Francesco Cosentino, Giovanni Scambia,

<h4>Objective</h4>To investigate whether neoadjuvant chemotherapy followed by interval debulking surgery is superior to primary debulking surgery in terms of perioperative complications and progression-free survival, in advanced epithelial ovarian, fallopian tube or primary peritoneal cancer patients with high tumor load.<h4>Methods</h4>Patients with advanced epithelial ovarian, fallopian tube or primary peritoneal cancer (stage ... Read more >>

Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2020, 30(11):1657-1664]

Cited: 3 times

View full text PDF listing >>



Sentinel lymph node mapping with indocyanine green in cervical cancer patients undergoing open radical hysterectomy: a single-institution series.

Nicolò Bizzarri, Pedone Anchora Luigi, Gabriella Ferrandina, Gian Franco Zannoni, Maria Vittoria Carbone, Camilla Fedele, Elena Teodorico, Valerio Gallotta, Salvatore Gueli Alletti, Vito Chiantera, Anna Fagotti, Giovanni Scambia, Francesco Fanfani,

<h4>Purpose</h4>To assess the rate of bilateral sentinel lymph node (SLN) detection with indocyanine green (ICG), to evaluate the sensitivity and the negative predictive value of cervical cancer patients undergoing open radical hysterectomy; to compare open versus minimally invasive SLN biopsy performance and to assess factors related to no/unilateral SLN mapping.<h4>Methods</h4>We ... Read more >>

J Cancer Res Clin Oncol (Journal of cancer research and clinical oncology)
[2021, 147(3):649-659]

Cited: 0 times

View full text PDF listing >>



Percutaneous-assisted vs mini-laparoscopic hysterectomy: comparison of ultra-minimally invasive approaches.

Stefano Cianci, Emanuele Perrone, Cristiano Rossitto, Francesco Fanfani, Alessandro Tropea, Antonio Biondi, Giovanni Scambia, Salvatore Gueli Alletti,

To assess the feasibility and the safety of the ultra-minimally invasive (U-MIS) approaches in gynecology, we compared our experience in percutaneous assisted hysterectomy (PSS-H) with a series of 3 mm mini-laparoscopy hysterectomy (m-LPS-H). 126 patients affected by benign and malignant gynecological conditions were considered eligible for minimally invasive hysterectomy: 80 patients ... Read more >>

Updates Surg (Updates in surgery)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Percutaneous-Assisted versus Laparoscopic Hysterectomy: A Prospective Comparison.

Emanuele Perrone, Cristiano Rossitto, Francesco Fanfani, Stefano Cianci, Anna Fagotti, Stefano Uccella, Giuseppe Vizzielli, Carmine Vascone, Stefano Restaino, Camilla Fedele, Farrah Layla Saleh, Giovanni Scambia, Salvatore Gueli Alletti,

<h4>Objective</h4>To evaluate the feasibility of percutaneous approach, we prospectively compared our experience in percutaneous-assisted hysterectomy (PSS-H) with that in a series of laparoscopic hysterectomies (LPS-Hs).<h4>Methods</h4>In this multicentric cohort study, from May 2015 to October 2017, 160 patients affected by benign and malignant gynecological conditions were considered eligible for minimally invasive ... Read more >>

Gynecol Obstet Invest (Gynecologic and obstetric investigation)
[2020, 85(4):318-326]

Cited: 0 times

View full text PDF listing >>



Laparoscopic sentinel node mapping with intracervical indocyanine green injection for endometrial cancer: the SENTIFAIL study - a multicentric analysis of predictors of failed mapping.

Giulio Sozzi, Francesco Fanfani, Roberto Berretta, Vito Andrea Capozzi, Stefano Uccella, Natalina Buono, Vincenzo Giallombardo, Mariano Catello Di Donna, Giorgia Monterossi, Stefano Restaino, Ilaria Capasso, Giorgia Dinoi, Giovanni Scambia, Vito Chiantera,

<h4>Objectives</h4>Laparoscopy is commonly used for endometrial cancer treatment, and sentinel lymph node (SLN) mapping has become the standard procedure for nodal assessment. Despite the standardization of the technique, there is no definitive data regarding its failure rate. The objective of this study is to identify factors associated with unsuccessful SLN ... Read more >>

Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2020, 30(11):1713-1718]

Cited: 0 times

View full text PDF listing >>



Role of minimally invasive surgery versus open approach in patients with early-stage uterine carcinosarcomas: a retrospective multicentric study.

Giacomo Corrado, Francesca Ciccarone, Francesco Cosentino, Francesco Legge, Andrea Rosati, Martina Arcieri, Luigi Carlo Turco, Camilla Certelli, Alex Federico, Enrico Vizza, Francesco Fanfani, Giovanni Scambia, Gabriella Ferrandina,

<h4>Objective</h4>The aim of this retrospective study was to compare surgical and survival outcome in only patients with early-stage UCSs managed by laparotomic surgery (LPT) versus minimally invasive surgery (MIS).<h4>Methods</h4>Data were retrospectively collected in four Italian different institutions. Inclusion criteria were UCS diagnosis confirmed by the definitive histological examination, and stage ... Read more >>

J Cancer Res Clin Oncol (Journal of cancer research and clinical oncology)
[2021, 147(3):845-852]

Cited: 0 times

View full text PDF listing >>



Laparoscopic high uterosacral ligament suspension (modified Shull technique): A case series and a step by step description of surgical procedure.

Lorenzo Vacca, Alessandro Lucidi, Giovanni Panico, Giuseppe Campagna, Stefano Restaino, Alfredo Ercoli, Giovanni Scambia, Francesco Fanfani,

<h4>Objective</h4>In this series we investigate the safety, feasibility and efficacy of our laparoscopic modified Shull technique describing the fundamental aspects of this surgical procedure in order to add a new feasible abdominal approach for apex resuspension.<h4>Study design</h4>A retrospective case series of 10 patients referring to our Urogynecological department for symptomatic ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2020, 253:83-89]

Cited: 0 times

View full text PDF listing >>



Surgery-related complications and long-term functional morbidity after segmental colo-rectal resection for deep infiltrating endometriosis (ENDO-RESECT morb).

Luigi Carlo Turco, Lucia Tortorella, Attilio Tuscano, Marco Antonio Palumbo, Anna Fagotti, Stefano Uccella, Francesco Fanfani, Gabriella Ferrandina, Nicola Nicolotti, Virginia Vargiu, Claudio Lodoli, Franco Scaldaferri, Giovanni Scambia, Francesco Cosentino,

<h4>Purpose</h4>Segmental resection has been generally associated with increased peri-operative risk of major complications. While major complications are widely acknowledged, minor complications, such as slight, to moderate infections, peripheral sensory disturbances, bladder voiding dysfunction, postoperative urinary obstruction, and sexual disorders are less reported. The aim of this study is to investigate ... Read more >>

Arch Gynecol Obstet (Archives of gynecology and obstetrics)
[2020, 302(4):983-993]

Cited: 0 times

View full text PDF listing >>



Pathological features, immunoprofile and mismatch repair protein expression status in uterine endometrioid carcinoma: focus on MELF pattern of myoinvasion.

Angela Santoro, Giuseppe Angelico, Frediano Inzani, Saveria Spadola, Damiano Arciuolo, Michele Valente, Teresa Musarra, Giovanni Capelli, Francesco Fanfani, Valerio Gallotta, Giovanni Scambia, Gian Franco Zannoni,

<h4>Aims</h4>Microcystic, elongated, and fragmented (MELF) pattern of myoinvasion has been related with increased risk of lympho-vascular space invasion (LVSI) and lymph node metastasis. We analysed a cohort of endometrioid endometrial carcinomas (EECs) to examine the relationships between the MELF pattern of invasion and the clinico-pathological and immunohistochemical features of EEC.<h4>Methods ... Read more >>

Eur J Surg Oncol (European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology)
[2021, 47(2):338-345]

Cited: 0 times

View full text PDF listing >>



Molecular and biological profile may discriminate between synchronous or metachronous endometrial and ovarian cancer.

Valentina Iacobelli, Gian Franco Zannoni, Benedetta Gui, Anna Fagotti, Giovanni Scambia, Francesco Fanfani,

Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2020, 30(7):1071-1076]

Cited: 0 times

View full text PDF listing >>



Should the Number of Metastatic Pelvic Lymph Nodes be Integrated into the 2018 Figo Staging Classification of Early Stage Cervical Cancer?

Luigi Pedone Anchora, Vittoria Carbone, Valerio Gallotta, Francesco Fanfani, Francesco Cosentino, Luigi Carlo Turco, Camilla Fedele, Nicolò Bizzarri, Giovanni Scambia, Gabriella Ferrandina,

<h4>Introduction</h4>Lymph node status has become part of the new staging system for cervical cancer (CC). It has been shown that patients staged as IIIC1 had heterogeneous prognoses and, in some cases, experienced better outcomes than patients with lower stages. We evaluated the impact of the number of metastatic pelvic lymph ... Read more >>

Cancers (Basel) (Cancers)
[2020, 12(6):]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.1361 s