Full Text Journal Articles by
Author Francesca Dalla Corte

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Return to Work After Coronavirus Disease 2019 Acute Respiratory Distress Syndrome and Intensive Care Admission: Prospective, Case Series at 6 Months From Hospital Discharge.

Luca Carenzo, Francesca Dalla Corte, Ryan W Haines, Chiara Palandri, Angelo Milani, Alessio Aghemo, Daniela Pini, Alessandro Protti, Maurizio Cecconi,

<h4>Objectives</h4>Joblessness is common in survivors from critical care. Our aim was to describe rates of return to work versus unemployment following coronavirus disease 2019 acute respiratory distress syndrome requiring intensive care admission.<h4>Design</h4>Single-center, prospective case series.<h4>Setting</h4>Critical Care Follow-Up Clinic, Humanitas Clinical and Research Center-IRCCS, Rozzano, Italy.<h4>Patients</h4>One hundred and one consecutive laboratory-confirmed ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):e1157-e1162]

Cited: 1 time

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Respiratory Drive in Patients with Sepsis and Septic Shock: Modulation by High-flow Nasal Cannula.

Tommaso Mauri, Elena Spinelli, Bertrand Pavlovsky, Domenico Luca Grieco, Irene Ottaviani, Maria Cristina Basile, Francesca Dalla Corte, Gabriele Pintaudi, Eugenio Garofalo, Annalisa Rundo, Carlo Alberto Volta, Antonio Pesenti, Savino Spadaro,

<h4>Background</h4>Experimental and pilot clinical data suggest that spontaneously breathing patients with sepsis and septic shock may present increased respiratory drive and effort, even in the absence of pulmonary infection. The study hypothesis was that respiratory drive and effort may be increased in septic patients and correlated with extrapulmonary determinant and ... Read more >>

Anesthesiology (Anesthesiology)
[2021, :]

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Time course of risk factors associated with mortality of 1260 critically ill patients with COVID-19 admitted to 24 Italian intensive care units.

Alberto Zanella, Gaetano Florio, Massimo Antonelli, Giacomo Bellani, Angela Berselli, Tiziana Bove, Luca Cabrini, Eleonora Carlesso, Gian Paolo Castelli, Maurizio Cecconi, Giuseppe Citerio, Irene Coloretti, Daniele Corti, Francesca Dalla Corte, Edoardo De Robertis, Giuseppe Foti, Roberto Fumagalli, Massimo Girardis, Riccardo Giudici, Lorenzo Guiotto, Thomas Langer, Lucia Mirabella, Daniela Pasero, Alessandro Protti, Marco V Ranieri, Roberto Rona, Luigia Scudeller, Paolo Severgnini, Savino Spadaro, Nino Stocchetti, Martina Viganò, Antonio Pesenti, Giacomo Grasselli, ,

<h4>Purpose</h4>To evaluate the daily values and trends over time of relevant clinical, ventilatory and laboratory parameters during the intensive care unit (ICU) stay and their association with outcome in critically ill patients with coronavirus disease 19 (COVID-19).<h4>Methods</h4>In this retrospective-prospective multicentric study, we enrolled COVID-19 patients admitted to Italian ICUs from ... Read more >>

Intensive Care Med (Intensive care medicine)
[2021, 47(9):995-1008]

Cited: 1 time

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Short-term health-related quality of life, physical function and psychological consequences of severe COVID-19.

Luca Carenzo, Alessandro Protti, Francesca Dalla Corte, Romina Aceto, Giacomo Iapichino, Angelo Milani, Alessandro Santini, Chiara Chiurazzi, Michele Ferrari, Enrico Heffler, Claudio Angelini, Alessio Aghemo, Michele Ciccarelli, Arturo Chiti, Theodore J Iwashyna, Margaret S Herridge, Maurizio Cecconi, ,

<h4>Background</h4>Survivors of severe COVID-19 are at risk of impaired health-related quality of life (HRQoL) and persistent physical and psychological disability after ICU and hospital discharge. The subsequent social burden is a major concern. We aimed to assess the short-term HRQoL, physical function and prevalence of post-traumatic stress symptoms of invasively ... Read more >>

Ann Intensive Care (Annals of intensive care)
[2021, 11(1):91]

Cited: 1 time

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Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients.

Thomas Langer, Matteo Brioni, Amedeo Guzzardella, Eleonora Carlesso, Luca Cabrini, Gianpaolo Castelli, Francesca Dalla Corte, Edoardo De Robertis, Martina Favarato, Andrea Forastieri, Clarissa Forlini, Massimo Girardis, Domenico Luca Grieco, Lucia Mirabella, Valentina Noseda, Paola Previtali, Alessandro Protti, Roberto Rona, Francesca Tardini, Tommaso Tonetti, Fabio Zannoni, Massimo Antonelli, Giuseppe Foti, Marco Ranieri, Antonio Pesenti, Roberto Fumagalli, Giacomo Grasselli, ,

<h4>Background</h4>Limited data are available on the use of prone position in intubated, invasively ventilated patients with Coronavirus disease-19 (COVID-19). Aim of this study is to investigate the use and effect of prone position in this population during the first 2020 pandemic wave.<h4>Methods</h4>Retrospective, multicentre, national cohort study conducted between February 24 ... Read more >>

Crit Care (Critical care (London, England))
[2021, 25(1):128]

Cited: 8 times

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Prone Position in Intubated, Mechanically Ventilated Patients with Coronavirus Disease-19.

Thomas Langer, Matteo Brioni, Amedeo Guzzardella, Eleonora Carlesso, Luca Cabrini, Gianpaolo Castelli, Francesca Dalla Corte, Edoardo De Robertis, Martina Favarato, Andrea Forastieri, Clarissa Forlini, Massimo Girardis, Domenico Luca Grieco, Lucia Mirabella, Valentina Noseda, Paola Previtali, Alessandro Protti, Roberto Rona, Francesca Tardini, Tommaso Tonetti, Fabio Zannoni, Massimo Antonelli, Giuseppe Foti, Marco Ranieri, Antonio Pesenti, Roberto Fumagalli, Giacomo GRASSELLI,

<h4>Background: </h4> Limited data are available on the use of prone position in intubated, invasively ventilated patients with Coronavirus disease-19 (COVID-19). Aim of this study is to investigate the use and effect of prone position in this population during the first 2020 pandemic wave. <h4>Methods: </h4>: Retrospective, multicentre, national cohort ... Read more >>

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Nasal high flow higher than 60 L/min in patients with acute hypoxemic respiratory failure: a physiological study.

Maria Cristina Basile, Tommaso Mauri, Elena Spinelli, Francesca Dalla Corte, Giacomo Montanari, Ines Marongiu, Savino Spadaro, Alessandro Galazzi, Giacomo Grasselli, Antonio Pesenti,

<h4>Background</h4>Nasal high flow delivered at flow rates higher than 60 L/min in patients with acute hypoxemic respiratory failure might be associated with improved physiological effects. However, poor comfort might limit feasibility of its clinical use.<h4>Methods</h4>We performed a prospective randomized cross-over physiological study on 12 ICU patients with acute hypoxemic respiratory failure. ... Read more >>

Crit Care (Critical care (London, England))
[2020, 24(1):654]

Cited: 0 times

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Gravitational distribution of regional opening and closing pressures, hysteresis and atelectrauma in ARDS evaluated by electrical impedance tomography.

Gaetano Scaramuzzo, Elena Spinelli, Savino Spadaro, Alessandro Santini, Donatella Tortolani, Francesca Dalla Corte, Antonio Pesenti, Carlo Alberto Volta, Giacomo Grasselli, Tommaso Mauri,

<h4>Background</h4>The physiological behavior of lungs affected by the acute respiratory distress syndrome (ARDS) differs between inspiration and expiration and presents heterogeneous gravity-dependent distribution. This phenomenon, highlighted by the different distribution of opening/closing pressure and by the hysteresis of the pressure-volume curve, can be studied by CT scan, but the technique ... Read more >>

Crit Care (Critical care (London, England))
[2020, 24(1):622]

Cited: 4 times

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Personalized Positive End-Expiratory Pressure in Acute Respiratory Distress Syndrome: Comparison Between Optimal Distribution of Regional Ventilation and Positive Transpulmonary Pressure.

Gaetano Scaramuzzo, Savino Spadaro, Francesca Dalla Corte, Andreas D Waldmann, Stephan H Böhm, Riccardo Ragazzi, Elisabetta Marangoni, Giacomo Grasselli, Antonio Pesenti, Carlo Alberto Volta, Tommaso Mauri,

<h4>Objectives</h4>Different techniques exist to select personalized positive end-expiratory pressure in patients affected by the acute respiratory distress syndrome. The positive end-expiratory transpulmonary pressure strategy aims to counteract dorsal lung collapse, whereas electrical impedance tomography could guide positive end-expiratory pressure selection based on optimal homogeneity of ventilation distribution. We compared the ... Read more >>

Crit Care Med (Critical care medicine)
[2020, 48(8):1148-1156]

Cited: 7 times

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Dynamic bedside assessment of the physiologic effects of prone position in acute respiratory distress syndrome patients by electrical impedance tomography.

Francesca Dalla Corte, Tommaso Mauri, Elena Spinelli, Marta Lazzeri, Cecilia Turrini, Marco Albanese, Chiara Abbruzzese, Alfredo Lissoni, Alessandro Galazzi, Nilde Eronia, Alfio Bronco, Elisabetta Maffezzini, Antonio Pesenti, Giuseppe Foti, Giacomo Bellani, Giacomo Grasselli,

<h4>Background</h4>Prone position (PP) improves acute respiratory distress syndrome (ARDS) survival by reducing the risk of ventilation-induced lung injury. However, inter-individual variability is a hallmark of ARDS and lung protection by PP might not be optimal in all patients. In the present study, we dynamically assessed physiologic effects of PP by ... Read more >>

Minerva Anestesiol (Minerva anestesiologica)
[2020, 86(10):1057-1064]

Cited: 2 times

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Expiratory flow limitation in intensive care: prevalence and risk factors.

Carlo Alberto Volta, Francesca Dalla Corte, Riccardo Ragazzi, Elisabetta Marangoni, Alberto Fogagnolo, Gaetano Scaramuzzo, Domenico Luca Grieco, Valentina Alvisi, Chiara Rizzuto, Savino Spadaro,

<h4>Background</h4>Expiratory flow limitation (EFL) is characterised by a markedly reduced expiratory flow insensitive to the expiratory driving pressure. The presence of EFL can influence the respiratory and cardiovascular function and damage the small airways; its occurrence has been demonstrated in different diseases, such as COPD, asthma, obesity, cardiac failure, ARDS, ... Read more >>

Crit Care (Critical care (London, England))
[2019, 23(1):395]

Cited: 6 times

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Effects of inspiratory flow on lung stress, pendelluft, and ventilation heterogeneity in ARDS: a physiological study.

Alessandro Santini, Tommaso Mauri, Francesca Dalla Corte, Elena Spinelli, Antonio Pesenti,

<h4>Background</h4>High inspiratory flow might damage the lungs by mechanisms not fully understood yet. We hypothesized that increasing inspiratory flow would increase lung stress, ventilation heterogeneity, and pendelluft in ARDS patients undergoing volume-controlled ventilation with constant tidal volume and that higher PEEP levels would reduce this phenomenon.<h4>Methods</h4>Ten ARDS patients were studied ... Read more >>

Crit Care (Critical care (London, England))
[2019, 23(1):369]

Cited: 5 times

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Noninvasive assessment of airflows by electrical impedance tomography in intubated hypoxemic patients: an exploratory study.

Tommaso Mauri, Elena Spinelli, Francesca Dalla Corte, Eleonora Scotti, Cecilia Turrini, Marta Lazzeri, Laura Alban, Marco Albanese, Donatella Tortolani, Yu-Mei Wang, Savino Spadaro, Jian-Xin Zhou, Antonio Pesenti, Giacomo Grasselli,

<h4>Background</h4>Noninvasive monitoring of maximal inspiratory and expiratory flows (MIF and MEF, respectively) by electrical impedance tomography (EIT) might enable early recognition of changes in the mechanical properties of the respiratory system due to new conditions or in response to treatments. We aimed to validate EIT-based measures of MIF and MEF ... Read more >>

Ann Intensive Care (Annals of intensive care)
[2019, 9(1):83]

Cited: 1 time

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Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study.

Tommaso Mauri, Eleonora Carlesso, Elena Spinelli, Cecilia Turrini, Francesca Dalla Corte, Riccarda Russo, Jean-Damien Ricard, Antonio Pesenti, Oriol Roca, Giacomo Grasselli,

The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at ... Read more >>

J Crit Care (Journal of critical care)
[2019, 53:183-185]

Cited: 7 times

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Altered erythroid-related miRNA levels as a possible novel biomarker for detection of autologous blood transfusion misuse in sport.

Jessica Gasparello, Nicola Lamberti, Chiara Papi, Ilaria Lampronti, Lucia Carmela Cosenza, Enrica Fabbri, Nicoletta Bianchi, Christel Zambon, Francesca Dalla Corte, Maurizio Govoni, Roberto Reverberi, Fabio Manfredini, Roberto Gambari, Alessia Finotti,

<h4>Background</h4>Autologous blood transfusion (ABT) is a performance-enhancing method prohibited in sport; its detection is a key issue in the field of anti-doping. Among novel markers enabling ABT detection, microRNAs (miRNAs) might be considered a promising analytical tool.<h4>Study design and methods</h4>We studied the changes of erythroid-related microRNAs following ABT, to identify ... Read more >>

Transfusion (Transfusion)
[2019, 59(8):2709-2721]

Cited: 2 times

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Nasal high flow: physiology, efficacy and safety in the acute care setting, a narrative review.

Tommaso Mauri, Yu-Mei Wang, Francesca Dalla Corte, Nadia Corcione, Elena Spinelli, Antonio Pesenti,

Nasal high flow (NHF) is a promising novel oxygen delivery device, whose mechanisms of action offer some beneficial effects over conventional oxygen systems. It is considered to have a number of physiological effects: it improves oxygenation, dynamic lung compliance, homogeneity and end expiratory lung volume; it decreases anatomical dead space ... Read more >>

Open Access Emerg Med (Open access emergency medicine : OAEM)
[2019, 11:109-120]

Cited: 2 times

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Fast skeletal troponin I, but not the slow isoform, is increased in patients under statin therapy: a pilot study.

Alessandro Trentini, Savino Spadaro, Valentina Rosta, Maria C Manfrinato, Carlo Cervellati, Francesca Dalla Corte, Stefania Hanau, Carlo A Volta, Tiziana Bellini,

<h4>Introduction</h4>Statin therapy is often associated with muscle complaints and increased serum creatine kinase (CK). However, although essential in determining muscle damage, this marker is not specific for skeletal muscle. Recent studies on animal models have shown that slow and fast isoforms of skeletal troponin I (ssTnI and fsTnI, respectively) can ... Read more >>

Biochem Med (Zagreb) (Biochemia medica)
[2019, 29(1):010703]

Cited: 0 times

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An open-loop, physiological model based decision support system can reduce pressure support while acting to preserve respiratory muscle function.

Savino Spadaro, Dan Stieper Karbing, Francesca Dalla Corte, Tommaso Mauri, Federico Moro, Antonio Gioia, Carlo Alberto Volta, Stephen Edward Rees,

<h4>Purpose</h4>To assess whether a clinical decision support system (CDSS) suggests PS and FIO<sub>2</sub> maintaining appropriate breathing effort, and minimizing FIO<sub>2</sub>.<h4>Materials</h4>Prospective, cross-over study in PS ventilated ICU patients. Over support (150% baseline) and under support (50% baseline) were applied by changing PS (15 patients) or PEEP (8 patients). CDSS advice was ... Read more >>

J Crit Care (Journal of critical care)
[2018, 48:407-413]

Cited: 3 times

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Positive end-expiratory pressure (PEEP) level to prevent expiratory flow limitation during cardiac surgery: study protocol for a randomized clinical trial (EFLcore study).

Elena Bignami, Savino Spadaro, Francesco Saglietti, Antonio Di Lullo, Francesca Dalla Corte, Marcello Guarnieri, Giulio de Simone, Ilaria Giambuzzi, Alberto Zangrillo, Carlo Alberto Volta,

<h4>Background</h4>Lung dysfunction commonly occurs after cardiopulmonary bypass (CPB). Randomized evidence suggests that the presence of expiratory flow limitation (EFL) in major abdominal surgery is associated with postoperative pulmonary complications. Appropriate lung recruitment and a correctly set positive end-expiratory pressure (PEEP) level may prevent EFL. According to the available data in ... Read more >>

Trials (Trials)
[2018, 19(1):654]

Cited: 0 times

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An Open-Loop, Physiologic Model-Based Decision Support System Can Provide Appropriate Ventilator Settings.

Dan Stieper Karbing, Savino Spadaro, Nilanjan Dey, Riccardo Ragazzi, Elisabetta Marangoni, Francesca Dalla Corte, Federico Moro, David Lodahl, Niklas Schurmann Hansen, Robert Winding, Stephen Edward Rees, Carlo Alberto Volta,

OBJECTIVES:To evaluate the physiologic effects of applying advice on mechanical ventilation by an open-loop, physiologic model-based clinical decision support system. DESIGN:Prospective, observational study. SETTING:University and Regional Hospitals' ICUs. PATIENTS:Varied adult ICU population. INTERVENTIONS:Advice were applied if accepted by physicians for a period of up to 4-8 hours. MEASUREMENTS AND MAIN ... Read more >>

Crit Care Med (Critical care medicine)
[2018, 46(7):e642-e648]

Cited: 4 times

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Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports.

Nicola Lamberti, Alessia Finotti, Jessica Gasparello, Ilaria Lampronti, Christel Zambon, Lucia Carmela Cosenza, Enrica Fabbri, Nicoletta Bianchi, Francesca Dalla Corte, Maurizio Govoni, Roberto Reverberi, Roberto Gambari, Fabio Manfredini,

The changes in hemoglobin (Hb) profile following autologous blood transfusion (ABT) for the first time were studied for anti-doping purposes. Twenty-four healthy, trained male subjects (aged 18‒40) were enrolled and randomized into either the transfusion (T) or control (C) groups. Blood samples were taken from the T subjects at baseline, ... Read more >>

Intern Emerg Med (Internal and emergency medicine)
[2018, 13(4):517-526]

Cited: 3 times

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Expiratory Flow Limitation as a Risk Factor for Pulmonary Complications After Major Abdominal Surgery.

Savino Spadaro, Gaetano Caramori, Chiara Rizzuto, Francesco Mojoli, Gianluca Zani, Riccardo Ragazzi, Giorgia Valpiani, Francesca Dalla Corte, Elisabetta Marangoni, Carlo Alberto Volta,

<h4>Background</h4>Postoperative pulmonary complications are major causes of postoperative morbidity and mortality. Although several risk factors have been associated with postoperative pulmonary complications, they are not consistent between studies and, even in those studies in which these factors were identified, the predictive power is low. We hypothesized that postoperative pulmonary complications ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2017, 124(2):524-530]

Cited: 13 times

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Fatigue in intensive care survivors one year after discharge.

Savino Spadaro, Maurizia Capuzzo, Giorgia Valpiani, Sara Bertacchini, Riccardo Ragazzi, Francesca Dalla Corte, Simona Terranova, Elisabetta Marangoni, Carlo Alberto Volta,

<h4>Background</h4>Fatigue has not been investigated in long-term Intensive Care Unit (ICU) survivors. This study aimed to assess fatigue through a specific instrument, namely the Functional Assessment of Chronic Illness Therapy Fatigue (FACIT-F) scale, in ICU survivors one year after hospital discharge. A secondary aim was to compare the findings of ... Read more >>

Health Qual Life Outcomes (Health and quality of life outcomes)
[2016, 14(1):148]

Cited: 7 times

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Can diaphragmatic ultrasonography performed during the T-tube trial predict weaning failure? The role of diaphragmatic rapid shallow breathing index.

Savino Spadaro, Salvatore Grasso, Tommaso Mauri, Francesca Dalla Corte, Valentina Alvisi, Riccardo Ragazzi, Valentina Cricca, Giulia Biondi, Rossella Di Mussi, Elisabetta Marangoni, Carlo Alberto Volta,

<h4>Background</h4>The rapid shallow breathing index (RSBI), which is the ratio between respiratory rate (RR) and tidal volume (VT), is one of the most widely used indices to predict weaning outcome. Whereas the diaphragm plays a fundamental role in generating VT, in the case of diaphragmatic dysfunction the inspiratory accessory muscles ... Read more >>

Crit Care (Critical care (London, England))
[2016, 20(1):305]

Cited: 24 times

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