Full Text Journal Articles by
Author Firuza D Patel

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To compare the optimal cytoreduction rate in advanced epithelial ovarian cancer stage III/IV after 3 versus 6 cycles of neoadjuvant chemotherapy.

Archana Kumari, Monika Thakur, S C Saha, Vanita Suri, G R V Prasad, Firuza D Patel, S Radhika,

This study aimed to compare the impact of 3 versus 6 cycles of neoadjuvant chemotherapy (NACT) on the optimal cytoreduction in patients of advanced ovarian malignancy during interval debulking surgery (IDS). Thirty patients with advanced-stage IIIc/IV epithelial ovarian cancer, fallopian tube cancer, and primary peritoneal cancer were randomly allocated to ... Read more >>

J Obstet Gynaecol (Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology)
[2020, :1-5]

Cited: 0 times

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Clinical outcomes with MRI-guided image-based brachytherapy in cervical cancer: An institutional experience.

Vijai Simha, Bhavana Rai, Firuza D Patel, Rakesh Kapoor, Suresh C Sharma, Oinam A Singh, Veenu Singla, Bhaswanth Dhanireddy, Sushmita Ghoshal,

PURPOSE:To evaluate the long-term disease control and toxicity to the organs at risk after dose-escalated image-based adaptive brachytherapy (BT) in cervical cancer. METHODS AND MATERIALS:Sixty patients of cervical cancer were treated with external radiotherapy 46 Gy in 23 fractions with weekly cisplatin and MRI-guided BT 7 Gy × 4 fractions with a ... Read more >>

Brachytherapy (Brachytherapy)
[2018, 17(2):345-351]

Cited: 2 times

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Chemoradiation therapy induces in vivo changes in gene promoter methylation & gene transcript expression in patients with invasive cervical cancer.

Swati Sood, Firuza D Patel, Radhika Srinivasan, Lakhbir K Dhaliwal,

<label>Background & objectives</label>Invasive cervical cancer patients are primarily treated with chemoradiation therapy. The overall and disease-free survival in these patients is variable and depends on the tumoral response apart from the tumour stage. This study was undertaken to assess whether in vivo changes in gene promoter methylation and transcript expression ... Read more >>

Indian J. Med. Res. (The Indian journal of medical research)
[2018, 147(2):151-157]

Cited: 2 times

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Gynecological Cancer as a Second Malignancy in Patients With Breast Cancer.

Budhi Singh Yadav, Suresh C Sharma, Firuza D Patel, Bhavana Rai, Sushmita Ghoshal,

PURPOSE:The aim of this study was to determine the incidence and risk factors for gynecological cancer as second malignancy (SM) after treatment of breast cancer (BC). METHODS AND MATERIALS:Between January 1985 and December 2007, a total of 2756 patients with BC were analyzed for gynecological cancers as an SM. Analysis ... Read more >>

Int. J. Gynecol. Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2017, 27(6):1298-1304]

Cited: 1 time

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Rhabdomyosarcoma of vulva in a young lady: A rare case report with review of literature.

Tapesh Bhattacharyya, Firuza D Patel, Radhika Srinivasan, Bhavana Rai, Pradeep Saha, R Nijhawan,

A 21-year-old lady presented with a rapidly progressive vulvar swelling with inguinal lymphadenopathy for 7 months. Pathological evaluation revealed it as a case of rhabdomyosarcoma. The disease behaved aggressively and she was treated with multimodality treatment. ... Read more >>

J Cancer Res Ther (Journal of cancer research and therapeutics)
[2015, 11(3):650]

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Cervical embryonal rhabdomyosarcoma and ovarian Sertoli-Leydig cell tumor with congenital absence of unilateral ovary.

Rubu Sunku, Rajan Duggal, Firuza D Patel, Bhavana Rai, Radhika Srinivasan, Raje Nijhawan,

We report this first case of synchronous cervical rhabdomyosarcoma and Sertoli-Leydig cell tumor (SLCT) of ovary with congenital absence of unilateral ovary and fallopian tube in a 16-year-old female patient. A review of the English-language literature identified only six cases of double malignancies with cervical rhabdomyosarcoma and SLCT but none ... Read more >>

J Cancer Res Ther (Journal of cancer research and therapeutics)
[2015, 11(3):654]

Cited: 0 times

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Leiomyosarcoma of the vagina: A rare entity with comprehensive review of the literature.

Divya Khosla, Firuza D Patel, Ritesh Kumar, Kiran K Gowda, Raje Nijhawan, Suresh C Sharma,

Primary malignant lesions of the vagina are uncommon, and vaginal sarcomas are even rarer. We describe a rare case of stage I, high-grade leiomyosarcoma of the vagina treated with combined modality treatment. A 39-year-old female presented with vaginal mass and underwent resection. Histopathological examination revealed atypical leiomyoma of the vagina ... Read more >>

Int J Appl Basic Med Res (International journal of applied & basic medical research)
[2014, 4(2):128-130]

Cited: 5 times

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Dosimetric comparison of vaginal vault ovoid brachytherapy versus intensity-modulated radiation therapy plans in postoperative patients of cervical carcinoma following whole pelvic radiotherapy.

Divya Khosla, Firuza D Patel, Arun S Oinam, Parsee Tomar, Suresh C Sharma,

INTRODUCTION: Dosimetric study to compare high dose rate (HDR) vaginal vault ovoid brachytherapy plan versus intensity-modulated radiation therapy (IMRT) boost plan for doses delivered to target volume and organs at risk (OAR) in postoperative patients of cervical carcinoma following whole pelvic radiotherapy (WPRT). MATERIALS AND METHODS: Fifteen postoperative patients of ... Read more >>

J Cancer Res Ther (Journal of cancer research and therapeutics)
[2014, 10(1):153-158]

Cited: 0 times

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CT and MR image fusion of tandem and ring applicator using rigid registration in intracavitary brachytherapy planning.

Arun S Oinam, Parsee Tomar, Firuza D Patel, Lakhwant Singh, Bhavana Rai, Amit Bahl,

The purpose of this study is to find the uncertainties in the reconstruction of MR compatible ring-tandem intracavitary applicators of high-dose rate image-based brachytherapy treatment planning using rigid registration of 3D MR and CT image fusion. Tandem and ring reconstruction in MR image based brachytherapy planning was done using rigid ... Read more >>

J Appl Clin Med Phys (Journal of applied clinical medical physics)
[2014, 15(2):4206]

Cited: 1 time

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Primitive neuroectodermal tumor of the uterine cervix diagnosed during pregnancy: a rare case with review of literature.

Divya Khosla, Bhavana Rai, Firuza D Patel, Sreejesh Sreedharanunni, Pranab Dey, Suresh C Sharma,

Primitive neuroectodermal tumors of the cervix are very rare. A 28-year-old pregnant woman presented with a cervical mass. The tumor was staged as IB2. The biopsy from tumor was suggestive of malignant small round cell tumor. She then underwent termination of pregnancy followed by radical hysterectomy. Based on morphologic and ... Read more >>

J. Obstet. Gynaecol. Res. (The journal of obstetrics and gynaecology research)
[2014, 40(3):878-882]

Cited: 5 times

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Magnitude and Implications of Interfraction Variations in Organ Doses during High Dose Rate Brachytherapy of Cervix Cancer: A CT Based Planning Study.

Santam Chakraborty, Firuza D Patel, Vijay M Patil, Arun S Oinam, Suresh C Sharma,

Background. Quantifying the interfraction dose variations in the organs at risk (OAR) in HDR intracavitary brachytherapy (HDR ICBT). Methods. Rectum and bladder were contoured in 44 patients of cervical carcinoma on CT after each fraction of HDR ICBT (9 Gy/2 fractions). Interfraction dose variations (VARact) were calculated. Rigid image registration of ... Read more >>

ISRN Oncol (ISRN oncology)
[2014, 2014:687365]

Cited: 3 times

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Sarcomas of the uterine cervix: a united and multidisciplinary approach is required.

Divya Khosla, Firuza D Patel, Ritesh Kumar,

Womens Health (Lond) (Women's health (London, England))
[2013, 9(6):501-504]

Cited: 2 times

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Literature review with PGI guidelines for delineation of clinical target volume for intact carcinoma cervix.

Anshuma Bansal, Firuza D Patel, Bhavana Rai, Abhishek Gulia, Bhaswanth Dhanireddy, S C Sharma,

For definitive treatment of carcinoma cervix with conformal radiation techniques, accurate target delineation is vitally important, yet a consensus definition of clinical target volume (CTV) remains variable within the literature. The aim of the present article is to review the guidelines for CTV delineation published in the literature and to ... Read more >>

J Cancer Res Ther (Journal of cancer research and therapeutics)
[2013, 9(4):574-582]

Cited: 3 times

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Bladder-rectum spacer balloon in high-dose-rate brachytherapy in cervix carcinoma.

Bhavana Rai, Firuza D Patel, Santam Chakraborty, Suresh C Sharma, Rakesh Kapoor, Abi Santhosh Aprem,

PURPOSE: To compare bladder and rectum doses with the use of a bladder-rectum spacer balloon (BRSB) versus standard gauze packing in the same patient receiving 2 high-dose-rate intracavitary brachytherapy fractions. METHODS AND MATERIALS: This was a randomized study to compare the reduction in bladder and rectum doses with the use ... Read more >>

Int. J. Radiat. Oncol. Biol. Phys. (International journal of radiation oncology, biology, physics)
[2013, 85(5):e217-22]

Cited: 7 times

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Pediatric astroblastoma: a rare case with a review of the literature.

Divya Khosla, Budhi S Yadav, Ritesh Kumar, Pallivi Agrawal, Nandita Kakkar, Firuza D Patel, Suresh C Sharma,

Astroblastoma is a rare glial tumor with uncertain histopathological origin and unpredictable clinical behavior. We present a case of an 11-year-old girl who presented with headache and blurring of vision for 2 months. A well-demarcated mass was found in the right frontoparietal lobe on a brain MRI. The patient was ... Read more >>

Pediatr Neurosurg (Pediatric neurosurgery)
[2012, 48(2):122-125]

Cited: 7 times

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Palliative care in India: current progress and future needs.

Divya Khosla, Firuza D Patel, Suresh C Sharma,

Despite its limited coverage, palliative care has been present in India for about 20 years. Obstacles in the growth of palliative care in India are too many and not only include factors like population density, poverty, geographical diversity, restrictive policies regarding opioid prescription, workforce development at base level, but also ... Read more >>

Indian J Palliat Care (Indian journal of palliative care)
[2012, 18(3):149-154]

Cited: 29 times

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CT or MRI for image-based brachytherapy in cervical cancer.

Rahul Krishnatry, Firuza D Patel, Paramjeet Singh, Suresh C Sharma, Arun S Oinam, Arvind K Shukla,

OBJECTIVE: To compare volumes and doses of tumour and organs at risk with computed tomography vs. magnetic resonance imaging in cervical cancer brachytherapy. METHODS: Seventeen previously untreated patients with cervical cancer suitable for radical treatment were included. All patients underwent brachytherapy using a magnetic resonance imaging-compatible applicator followed by both ... Read more >>

Jpn. J. Clin. Oncol. (Japanese journal of clinical oncology)
[2012, 42(4):309-313]

Cited: 12 times

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Acrometastasis to hand in vaginal carcinoma: a rare entity.

Divya Khosla, Bhavana Rai, Firuza D Patel, Simit Sapkota, Radhika Srinvasan, Suresh C Sharma,

Although metastases to bones from solid tumors are very common, involvement of small bones of the hands is extremely rare. We report the first case of acrometastasis in vaginal carcinoma. We present a 65-year-old multiparous woman with FIGO Stage II vaginal carcinoma. The patient received treatment with external beam radiotherapy ... Read more >>

J Cancer Res Ther (Journal of cancer research and therapeutics)
[2012, 8(3):430-432]

Cited: 2 times

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Sarcomas of uterine cervix: clinicopathological features, treatment, and outcome.

Divya Khosla, Ruchi Gupta, Radhika Srinivasan, Firuza D Patel, Arvind Rajwanshi,

OBJECTIVE:Sarcomas constitute less than 1% of all cervical malignancies. The objective of this study was to determine the presentation, pathological findings, treatment, and outcome of patients with cervical sarcoma. METHODS AND MATERIALS:A retrospective analysis of 8 cases of cervical sarcoma diagnosed over a 4-year period from 2006 to 2009 was ... Read more >>

Int. J. Gynecol. Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2012, 22(6):1026-1030]

Cited: 11 times

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Differential expression of Fas family members and Bcl-2 family members in benign versus malignant epithelial ovarian cancer (EOC) in North Indian population.

Parvesh Chaudhry, Radhika Srinivasan, Firuza D Patel,

Epithelial ovarian cancer (EOC) represents the most challenging of gynecological malignancies. Defective apoptosis is a major causative factor in the development and progression of cancer. The two important pathways of apoptosis are extrinsic death receptor pathway (Fas family) and intrinsic mitochondrial pathway (Bcl-2 family). In this study, differential protein expression ... Read more >>

Mol. Cell. Biochem. (Molecular and cellular biochemistry)
[2012, 368(1-2):119-126]

Cited: 6 times

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Treatment of therapy related acute promyelocytic leukemia with the combination of all trans retinoic acid and arsenic trioxide without chemotherapy: a series of three patients.

Pankaj Malhotra, Neelam Varma, Niraj Arora, Reena Das, Alok Nath, Firuza D Patel, Subhash Varma,

Leuk. Lymphoma (Leukemia & lymphoma)
[2010, 51(5):933-936]

Cited: 9 times

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Quad shot: a short but effective schedule for palliative radiation for head and neck carcinoma.

Sushmita Ghoshal, Santam Chakraborty, Neeru Moudgil, Manreet Kaur, Firuza D Patel,

BACKGROUND: To evaluate a 2-day course of palliative radiation in patients diagnosed to have inoperable or metastatic head and neck carcinoma. AIM: To evaluate the symptom relief and quality of life in these patients after this short course of radiation. SETTINGS AND DESIGN: A pilot study was conducted in a ... Read more >>

Indian J Palliat Care (Indian journal of palliative care)
[2009, 15(2):137-140]

Cited: 16 times

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Expression of the major fas family and Bcl-2 family of proteins in epithelial ovarian cancer (EOC) and their correlation to chemotherapeutic response and outcome.

Parvesh Chaudhry, Radhika Srinivasan, Firuza D Patel,

Platinum-based chemotherapeutic drugs trigger apoptosis, and deregulation of apoptotic pathways may contribute to chemoresistance. We investigated the role of major Fas and Bcl-2 family members as predictors of response to platinum-based chemotherapy in epithelial ovarian cancer (EOC). The expression of Fas, FasL, FAP-1, Bax, Bcl-2, and Bcl-X(L) was analyzed in ... Read more >>

Oncol. Res. (Oncology research)
[2010, 18(11-12):549-559]

Cited: 10 times

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Utility of gene promoter methylation in prediction of response to platinum-based chemotherapy in epithelial ovarian cancer (EOC).

Parvesh Chaudhry, Radhika Srinivasan, Firuza D Patel,

The aim was to determine whether promoter methylation of BRCA1, MGMT, MLH1, RASSF1A, and p16 genes could predict response to platinum-based chemotherapy. Thirty-five subjects with epithelial ovarian cancer (EOC) treated by platinum-based chemotherapy were recruited. Methylation-specific polymerase chain reaction was carried out and the methylation index (MI) was also derived. ... Read more >>

Cancer Invest. (Cancer investigation)
[2009, 27(8):877-884]

Cited: 20 times

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Steroid receptors, HER2/neu and Ki-67, in endometrioid type of endometrial carcinoma: Correlation with conventional histomorphological features of prognosis.

Dimple Chakravarty, Nalini Gupta, Jayant Shastri Goda, Radhika Srinivasan, Firuza D Patel, Lakhbir Dhaliwal,

Endometrial proliferation is regulated by steroid receptors such as estrogen receptor alpha (ERalpha), estrogen receptor beta (ERbeta) and progesterone receptor (PR). HER2/neu is an important growth factor receptor which affects cell proliferation and Ki67 is a marker of cellular proliferation. Their interaction in endometrioid type of endometrial carcinoma is still ... Read more >>

Acta Histochem. (Acta histochemica)
[2010, 112(4):355-363]

Cited: 8 times

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