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Zero-valent iron nanomaterial Fe0@Fe2MnO4 for ultrasensitive electroanalysis of As(iii): Fe0 influenced surficial redox potential.

Meng Yang, Feng Xie, Shan-Shan Li, Chu-Hong Lin, Xing-Jiu Huang, Wen-Qing Liu,

A novel zero-valent iron nanomaterial (Fe<sup>0</sup>@Fe<sub>2</sub>MnO<sub>4</sub>) was synthesized and achieved an ultrasensitive electrochemical detection of As(iii). It was found that the enhanced sensitivity is attributed to the surficial catalytic redox couple Fe(ii)/Fe(iii) induced by Fe<sup>0</sup> of Fe<sup>0</sup>@Fe<sub>2</sub>MnO<sub>4</sub>. Besides, the catalytic kinetics was modelled and simulated, and the strong influence of ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, 57(11):1324-1327]

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A predictive score for progression of COVID-19 in hospitalized persons: a cohort study.

Jingbo Xu, Weida Wang, Honghui Ye, Wenzheng Pang, Pengfei Pang, Meiwen Tang, Feng Xie, Zhitao Li, Bixiang Li, Anqi Liang, Juan Zhuang, Jing Yang, Chunyu Zhang, Jiangnan Ren, Lin Tian, Zhonghe Li, Jinyu Xia, Robert P Gale, Hong Shan, Yang Liang,

Accurate prediction of the risk of progression of coronavirus disease (COVID-19) is needed at the time of hospitalization. Logistic regression analyses are used to interrogate clinical and laboratory co-variates from every hospital admission from an area of 2 million people with sporadic cases. From a total of 98 subjects, 3 ... Read more >>

NPJ Prim Care Respir Med (NPJ primary care respiratory medicine)
[2021, 31(1):33]

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DUDA-Net: a double U-shaped dilated attention network for automatic infection area segmentation in COVID-19 lung CT images.

Feng Xie, Zheng Huang, Zhengjin Shi, Tianyu Wang, Guoli Song, Bolun Wang, Zihong Liu,

<h4>Purpose</h4>The global health crisis caused by coronavirus disease 2019 (COVID-19) is a common threat facing all humankind. In the process of diagnosing COVID-19 and treating patients, automatic COVID-19 lesion segmentation from computed tomography images helps doctors and patients intuitively understand lung infection. To effectively quantify lung infections, a convolutional neural ... Read more >>

Int J Comput Assist Radiol Surg (International journal of computer assisted radiology and surgery)
[2021, :]

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Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation.

Zhen Yang, Feng Xu, Haizhou Wang, Andrew E Teschendorff, Feng Xie, Yungang He,

<h4>Background</h4>Disruption of DNA methylation (DNAm) is one of the key signatures of cancer, however, detailed mechanisms that alter the DNA methylome in cancer remain to be elucidated.<h4>Methods</h4>Here we present a novel integrative analysis framework, called MeLncTRN (Methylation mediated LncRNA Transcriptional Regulatory Network), that integrates genome-wide transcriptome, DNA methylome and copy ... Read more >>

EBioMedicine (EBioMedicine)
[2021, 68:103399]

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Urinary Molecular Pathology for Patients with Newly Diagnosed Urothelial Bladder Cancer.

Ruiyun Zhang, Jingyu Zang, Feng Xie, Yue Zhang, Yiqiu Wang, Ying Jing, Yi Zhang, Zhaoxiong Chen, Akezhouli Shahatiaili, Mei-Chun Cai, Zhixin Zhao, Pan Du, Shidong Jia, Guanglei Zhuang, Haige Chen,

<h4>Purpose</h4>Next-generation sequencing (NGS)-based profiling of both urinary tumor DNA (utDNA) and circulating tumor DNA (ctDNA) shows promise for noninvasive detection and surveillance of urothelial bladder cancer (UBC). However, the analytic performance of these assays remains undefined in the real-world setting. Here, we sought to evaluate the concordance between tumor DNA ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001878]

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Facet engineering in metal organic frameworks to improve their electrochemical activity for water oxidation.

Jiawei Wan, Di Liu, Hai Xiao, Hongpan Rong, Sheng Guan, Feng Xie, Dingsheng Wang, Yadong Li,

The facet effect has been well demonstrated for nanocrystal catalysis, however it is rarely revealed in metal organic frameworks (MOFs). Herein, we present a facile way to construct 2D zeolitic imidazolate framework-67 (ZIF-67) with dominant exposure of the (002) facets. We discovered that the ZIF-67 (002) facet exhibited the highest ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(31):4316-4319]

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Cell-free DNA comparative analysis of genomic landscape of first-line hormone-receptor positive metastatic breast cancer from US and China

Xiao-Ran Liu, Davis Andrew, Feng Xie, Xinyu Gui, Yifei Chen, Qiang Zhang, Lorenzo Gerratana, Youbin Zhang, Ami Shah, Amir Behdad, Firas Wehbe, Yong Huang, Jianjun Yu, Pan Du, Shidong Jia, Huiping Li, Massimo Cristofanilli,

<h4>Purpose: </h4> Comparison of mutation landscape across ethnics using the identical detecting platform is important. We explored the differential genomic landscape of patients with hormone-receptor positive (HR+), HER2-negative MBC of first line recurrence or Stage IV at diagnosis from the United States (US) and China (CN). <h4>Methods: </h4> Twenty-seven US ... Read more >>

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Root Extract of Lindera aggregata (Sims) Kosterm. Modulates the Th17/Treg Balance to Attenuate DSS-Induced Colitis in Mice by IL-6/STAT3 Signaling Pathway.

Huimin Lai, Zhengbiao Yang, Zhaohuan Lou, Feng Li, Feng Xie, Wei Pan, Cong Xu, Lili Zhang, Sheng Zhang, Lijiang Zhang, Mincong Huang,

Ulcerative colitis (UC) is a chronic, idiopathic and relapsing inflammatory disease of the gastrointestinal tract that has a prolonged disease duration. <i>Lindera aggregata</i> (Sims) Kosterm. is a traditional Chinese herb which has been used to treat gastrointestinal diseases for thousand years. However, there are few reports about the application of ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2021, 12:615506]

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Guidelines that use the GRADE approach often fail to provide complete economic information for recommendations: a Systematic Survey.

John J Riva, Meha Bhatt, David J Brunarski, Jason W Busse, Carolina C Martins, Feng Xie, Holger J Schünemann, Jan L Brozek,

<h4>Objective</h4>Little is known about how developers and panel members report cost and cost effectiveness considerations in GRADE guideline Evidence-to-Decision (EtD) frameworks. A systematic survey was conducted to explore approaches and factors contributing to variability in economic information reporting.<h4>Study design and setting</h4>Guideline organization websites were systematically searched to create a convenience ... Read more >>

J Clin Epidemiol (Journal of clinical epidemiology)
[2021, :]

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Anti-Myocardial Ischemia Reperfusion Injury Mechanism of Dried Ginger-Aconite Decoction Based on Network Pharmacology.

Feng Xie, Yuan-Yuan Wu, Guang-Jing Duan, Bin Wang, Feng Gao, Pei-Feng Wei, Lin Chen, A-Ping Liu, Min Li,

Dried ginger-aconite decoction (DAD) is a traditional Chinese medicine (TCM) formula that has been extensively used in the treatment of myocardial ischemia reperfusion injury (MI/RI). However, its specific mechanism against MI/RI has not been reported yet. Therefore, this paper studies the potential active components and mechanism of DAD against MI/RI ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2021, 12:609702]

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DETECTION OF LUNG AND MYOCARDIAL PERFUSION ABNORMALITIES IN ACUTE COVID-19 INFECTION WITH BEDSIDE ULTRASOUND

Thomas Richard Porter, Karla Costello, Joan Olson, Feng Xie, Jonathan Lindner,

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2021, 77(18):1299-1299]

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Maturation conditions, post-ovulatory age, medium pH, and ER stress affect [Ca2+]i oscillation patterns in mouse oocytes.

Rui-Ying Yuan, Feng Wang, Sen Li, Jun-Yu Ma, Lei Guo, Xiao-Long Li, Hai-Jing Zhu, Xie Feng, Qian-Nan Li, Qian Zhou, Zi-Bin Lin, Heide Schatten, Xiang-Hong Ou,

Insufficiency of oocyte activation impairs the subsequent embryo development in assisted reproductive technology (ART). Intracellular Ca<sup>2+</sup> concentration ([Ca<sup>2+</sup>]i) oscillations switch the oocytes to resume the second meiosis and initiate embryonic development. However, the [Ca<sup>2+</sup>]i oscillation patterns in oocytes are poorly characterized. In this study, we investigated the effects of various ... Read more >>

J Assist Reprod Genet (Journal of assisted reproduction and genetics)
[2021, :]

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Study on potential energy curves and ro-vibrational energies of DT, HT and T2 molecules.

Jia Fu, Jun Jian, Shanshan Long, Zhixiang Fan, Qunchao Fan, Feng Xie, Yi Zhang, Jie Ma,

Accurately monitoring and effectively controlling the tritium compounds based on their ro-vibrational energy structure are important issues in various nuclear systems. Because of their radioactivity, it is difficult to obtain the corresponding energies directly through experiments. In this paper, the potential energy curves and the corresponding ro-vibrational full spectrum of ... Read more >>

Spectrochim Acta A Mol Biomol Spectrosc (Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy)
[2021, 260:119913]

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Efficacy of Sonothrombolysis Using Acoustically Activated Perflutren Nanodroplets versus Perflutren Microbubbles.

Soufiane El Kadi, Lijun Qian, Ping Zeng, John Lof, Elizabeth Stolze, Feng Xie, Albert C van Rossum, Otto Kamp, Carr Everbach, Thomas R Porter,

Nanoscale-diameter liquid droplets from commercially available microbubbles may optimize thrombus permeation and subsequent thrombus dissolution (TD). Thrombi were made using fresh porcine arterial whole blood and placed in an in vitro vascular simulation. A diagnostic ultrasound probe in contact with a tissue-mimicking phantom tested intermittent high-mechanical-index (HMI) fundamental multipulse (focused ... Read more >>

Ultrasound Med Biol (Ultrasound in medicine & biology)
[2021, 47(7):1814-1825]

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A Strategy for Integrative Reconstruction of Midface Defects Using an Extended Forehead Flap.

Shuang-Bai Zhou, Bo-Wen Gao, Poh-Ching Tan, Hui-Zhong Zhang, Qing-Feng Li, Feng Xie,

<b>Background:</b> Midface reconstruction is challenging because the structures and deformities involved are complicated. In this study, we present a strategy for integrally reconstructing nasal and midface defects, including hair-bearing defects, using extended forehead-expanded flaps. <b>Methods:</b> From 2015 to 2018, a total of 22 patients with midface defects underwent reconstruction with ... Read more >>

Facial Plast Surg Aesthet Med (Facial plastic surgery & aesthetic medicine)
[2021, :]

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Analysis of the predictive value of real-time shear wave elastography in detecting the elastic hardness of liver and spleen in patients with portal hypertension of hepatitis B cirrhosis.

Peng Wang, Ping Wu, Binbin Jia, Jingru Liang, Zhiyong Han, Feng Xie,

Panminerva Med (Panminerva medica)
[2021, :]

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Differences in Lung Cancer Treatment Preferences Among Oncologists, Patients and Family Members: A Semi-Structured Qualitative Study in China.

Xiaoning He, Mengqian Zhang, Jing Wu, Song Xu, Xiangli Jiang, Ziping Wang, Shucai Zhang, Feng Xie,

<h4>Background</h4>Cancer treatment decision-making often needs to balance benefits, harms, and costs. This study sought to identify the differences in cancer treatment preference among oncologists, patients and their family members in China.<h4>Methods</h4>A semi-structured face-to-face qualitative interview was conducted among oncologists, patients and their family members recruited in four tertiary hospitals in ... Read more >>

Patient Prefer Adherence (Patient preference and adherence)
[2021, 15:775-783]

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Evaluating the conduct and application of health utility studies: a review of critical appraisal tools and reporting checklists.

Michael J Zoratti, A Simon Pickard, Peep F M Stalmeier, Daniel Ollendorf, Andrew Lloyd, Kelvin K W Chan, Don Husereau, John E Brazier, Murray Krahn, Mitchell Levine, Lehana Thabane, Feng Xie, ,

<h4>Background</h4>Published health utility studies are increasingly cited in cost-utility analyses to inform reimbursement decision-making. However, there is limited guidance for investigators looking to systematically evaluate the methodological quality of health utility studies or their applicability to decision contexts.<h4>Objective</h4>To describe how health utility concepts are reflected in tools intended for use ... Read more >>

Eur J Health Econ (The European journal of health economics : HEPAC : health economics in prevention and care)
[2021, :]

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Cost-effectiveness analysis of colorectal cancer screening in a low incidence country: The case of Saudi Arabia.

Steffie K Naber, Majid A Almadi, Gordon Guyatt, Feng Xie, Iris Lansdorp-Vogelaar,

<h4>Background</h4>Colorectal cancer (CRC) screening is cost-effective in many Western countries, and many have successfully implemented CRC screening programs. For countries with a lower CRC incidence, like Saudi Arabia, the value of CRC screening is less evident and requires careful weighing of harms, benefits, and costs.<h4>Methods</h4>We used the MISCAN-Colon microsimulation model ... Read more >>

Saudi J Gastroenterol (Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association)
[2021, :]

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Using Published Health Utilities in Cost-Utility Analyses: Discrepancies and Issues in Cardiovascular Disease.

Ting Zhou, Zhiyuan Chen, Hongchao Li, Feng Xie,

<h4>Background</h4>Health utilities are commonly used as quality weights to calculate quality-adjusted life years in cost-utility analysis (CUA). However, if published health utilities are not properly used, the credibility of CUA could be affected.<h4>Objectives</h4>To identify discrepancies in using published health utilities in CUAs for cardiovascular disease (CVD).<h4>Methods</h4>CVD CUAs in the Tufts ... Read more >>

Med Decis Making (Medical decision making : an international journal of the Society for Medical Decision Making)
[2021, :272989X211004532]

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Expression of Concern to: Downregulation of NIN/RPN12 binding protein inhibit the growth of human hepatocellular carcinoma cells.

Zaiming Lu, Qiyong Guo, Aizhong Shi, Feng Xie, Qingjie Lu,

Mol Biol Rep (Molecular biology reports)
[2021, 48(4):3889]

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Double-strand breaks induce short scale DNA replication and damage amplification in the fully-grown mouse oocytes.

Jun-Yu Ma, Xie Feng, Feng-Yun Xie, Sen Li, Lei-Ning Chen, Shi-Ming Luo, Shen Yin, Xiang-Hong Ou,

Break-induced replication (BIR) is essential for the repair of DNA double-strand breaks (DSBs) with single ends. DSBs-induced microhomology-mediated BIR (mmBIR) and template-switching can increase the risk of complex genome rearrangement. In addition, DSBs can also induce the multi-invasion-mediated DSB amplification. The mmBIR-induced genomic rearrangement has been identified in cancer cells ... Read more >>

Genetics (Genetics)
[2021, :]

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Long-term prognostic value of stress myocardial perfusion echocardiography in patients with coronary artery disease: a meta-analysis.

Lijun Qian, Feng Xie, Di Xu, T R Porter,

<h4>Aims </h4>To evaluate the prognostic value of myocardial perfusion (MP) imaging during contrast stress echocardiography (cSE) in patients with known or suspected coronary artery disease (CAD).<h4>Methods and results </h4>A search in PubMed, Embase databases, and the Cochrane library was conducted through May 2019. The Cochran Q statistic and the I2 statistic were ... Read more >>

Eur Heart J Cardiovasc Imaging (European heart journal. Cardiovascular Imaging)
[2021, 22(5):553-562]

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A method for the automatic detection of myopia in Optos fundus images based on deep learning.

Zhengjin Shi, Tianyu Wang, Zheng Huang, Feng Xie, Guoli Song,

Myopia detection is significant for preventing irreversible visual impairment and diagnosing myopic retinopathy. To improve the detection efficiency and accuracy, a Myopia Detection Network (MDNet) that combines the advantages of dense connection and Residual Squeeze-and-Excitation attention is proposed in this paper to automatically detect myopia in Optos fundus images. First, ... Read more >>

Int J Numer Method Biomed Eng (International journal for numerical methods in biomedical engineering)
[2021, :e3460]

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Decision Analysis in SHared decision making for Thromboprophylaxis during Pregnancy (DASH-TOP): a sequential explanatory mixed methods pilot study protocol.

Brittany Humphries, Montserrat León-García, Shannon Bates, Gordon Guyatt, Mark Eckman, Rohan D'Souza, Nadine Shehata, Susan Jack, Pablo Alonso-Coello, Feng Xie,

<h4>Introduction</h4>Decision analysis is a quantitative approach to decision making that could bridge the gap between decisions based solely on evidence and the unique values and preferences of individual patients, a feature especially important when existing evidence cannot support clear recommendations and there is a close balance between harms and benefits ... Read more >>

BMJ Open (BMJ open)
[2021, 11(3):e046021]

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