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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1063-e1143]

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Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):1974-1982]

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Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Intensive Care Med (Intensive care medicine)
[2021, :]

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The Saudi Critical Care Society Practice Guidelines on the Management of COVID-19 in the ICU: Therapy Section

Waleed Alhazzani, Mohammed Alshahrani, Fayez Alshamsi, Ohoud Aljuhani, Khalid Eljaaly, Samaher Hashim, Rakan Alqahtani, Doaa Alsaleh, Zainab Al Duhailib, Haifa Algethamy, Tariq Al-Musawi, Thamir Alshammari, Abdullah Alqarni, Danya Khoujah, Wail Tashkandi, Talal Dahhan, Najla Almutairi, Haleema Alserehi, Maytha Al-Yahya, Bandar Al-Judaibi, Yaseen Arabi, Jameel Abualenain, Jawaher Alotaibi, Ali Albshabshe, Reham Alharbi, Fahad Al-Hameed, Alyaa Elhazmi, Reem Almaghrabi, Fatma Almaghlouth, Malak Abedalthagafi, Noor Al Khathlan, Faisal Al-Suwaidan, Reem Bunyan, Bandar Baw, Ghassan Alghamdi, Manal Al Hazmi, Yasser Mandourah, Abdullah Assiri, Mushira Enani, Maha Alawi, Reem Aljindan, Ahmed Aljabbary, Abdullah Alrbiaan, Fahd Algurashi, Abdulmohsen Alsaawi, Thamer Alenazi, Mohammed Alsultan, Saleh Alqahtani, Ziad Memish, Jaffar Al-Tawfiq, Ahmed Al-Jedai,

<h4>Background: </h4> The rapid increase in coronavirus disease 2019 (COVID-19) cases during the subsequent waves in Saudi Arabia and other countries prompted the Saudi Critical Care Society (SCCS) to put together a panel of experts to issue evidence-based recommendations for the management of COVID-19 in the intensive care unit (ICU). ... Read more >>

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Antemortem Heparin in Organ Donation after Circulatory Death Determination (DCDD): A Systematic Review of the Literature.

Kimia Honarmand, Fayez Alshamsi, Farid Foroutan, Bram Rochwerg, Emilie Belley-Cote, Graham Mclure, Frederick D'Aragon, Ian M Ball, Alp Sener, Markus Selzner, Gordon Guyatt, Maureen O Meade,

Donation after circulatory death determination (DCDD) frequently involves antemortem heparin administration to mitigate peri-arrest microvascular thrombosis. We systematically reviewed the literature to: (1) describe heparin administration practices, and (2) explore the effects on transplant outcomes. We searched MEDLINE and EMBASE for studies reporting DCDD heparin practices including use, dosage, and ... Read more >>

Transplantation (Transplantation)
[2021, :]

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Admission levels of Soluble Urokinase Plasminogen Activator Receptor (suPAR) are Associated with the Development of Severe Complications in Hospitalised COVID-19 Patients: A Prospective Cohort Study.

Abderrahim Oulhaj, Ahmed R Alsuwaidi, Abubaker Suliman, Huda Gasmelseed, Shaima Khan, Shamma Alawi, Yaman Hukan, Junu George, Fayez Alshamsi, Farrukh Sheikh, Zahir Osman Eltahir Babiker, Juergen Prattes, Harald Sourij,

<h4>Objective</h4>To examine the association between plasma levels of the soluble urokinase plasminogen activator receptor (suPAR) and the incidence of severe complications of COVID-19.<h4>Methods</h4>403 RT-PCR-confirmed COVID-19 patients were recruited and prospectively followed-up at a major hospital in the United Arab Emirates. The primary endpoint was time from admission until the development ... Read more >>

Int J Infect Dis (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2021, 107:188-194]

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Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update.

Waleed Alhazzani, Laura Evans, Fayez Alshamsi, Morten Hylander Møller, Marlies Ostermann, Hallie C Prescott, Yaseen M Arabi, Mark Loeb, Michelle Ng Gong, Eddy Fan, Simon Oczkowski, Mitchell M Levy, Lennie Derde, Amy Dzierba, Bin Du, Flavia Machado, Hannah Wunsch, Mark Crowther, Maurizio Cecconi, Younsuck Koh, Lisa Burry, Daniel S Chertow, Wojciech Szczeklik, Emilie Belley-Cote, Massimiliano Greco, Malgorzata Bala, Ryan Zarychanski, Jozef Kesecioglu, Allison McGeer, Leonard Mermel, Manoj J Mammen, Sheila Nainan Myatra, Amy Arrington, Ruth Kleinpell, Giuseppe Citerio, Kimberley Lewis, Elizabeth Bridges, Ziad A Memish, Naomi Hammond, Frederick G Hayden, Muhammed Alshahrani, Zainab Al Duhailib, Greg S Martin, Lewis J Kaplan, Craig M Coopersmith, Massimo Antonelli, Andrew Rhodes,

<h4>Background</h4>The coronavirus disease 2019 pandemic continues to affect millions worldwide. Given the rapidly growing evidence base, we implemented a living guideline model to provide guidance on the management of patients with severe or critical coronavirus disease 2019 in the ICU.<h4>Methods</h4>The Surviving Sepsis Campaign Coronavirus Disease 2019 panel has expanded to ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(3):e219-e234]

Cited: 37 times

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The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis: A systematic review and meta-analysis of randomized trials.

Kimberley Lewis, Dipayan Chaudhuri, Fayez Alshamsi, Laiya Carayannopoulos, Karin Dearness, Zain Chagla, Waleed Alhazzani, ,

<h4>Background</h4>Populations such as healthcare workers (HCW) that are unable to practice physical distancing are at high risk of acquiring Coronavirus disease-2019 (COVID-19). In these cases pharmacological prophylaxis would be a solution to reduce severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) transmission. Hydroxychloroquine has in vitro antiviral properties against SARS CoV-2. ... Read more >>

PLoS One (PloS one)
[2021, 16(1):e0244778]

Cited: 11 times

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Temperature control in critically ill patients with fever: A meta-analysis of randomized controlled trials.

Abdullah Sakkat, Mustafa Alquraini, Jafar Aljazeeri, Mohammed A M Farooqi, Fayez Alshamsi, Waleed Alhazzani,

<h4>Purpose</h4>Fever is frequently encountered in ICU. It is unclear if targeted temperature control is beneficial in critically ill patients with suspected or confirmed infection. We conducted a systemic review and meta-analysis to answer this question.<h4>Methods</h4>We systematically reviewed major databases before January 2020 to identify randomized controlled trials (RCTs) that compared ... Read more >>

J Crit Care (Journal of critical care)
[2021, 61:89-95]

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Managing ICU surge during the COVID-19 crisis: rapid guidelines.

Shadman Aziz, Yaseen M Arabi, Waleed Alhazzani, Laura Evans, Giuseppe Citerio, Katherine Fischkoff, Jorge Salluh, Geert Meyfroidt, Fayez Alshamsi, Simon Oczkowski, Elie Azoulay, Amy Price, Lisa Burry, Amy Dzierba, Andrew Benintende, Jill Morgan, Giacomo Grasselli, Andrew Rhodes, Morten H Møller, Larry Chu, Shelly Schwedhelm, John J Lowe, Du Bin, Michael D Christian,

Given the rapidly changing nature of COVID-19, clinicians and policy makers require urgent review and summary of the literature, and synthesis of evidence-based guidelines to inform practice. The WHO advocates for rapid reviews in these circumstances. The purpose of this rapid guideline is to provide recommendations on the organizational management ... Read more >>

Intensive Care Med (Intensive care medicine)
[2020, 46(7):1303-1325]

Cited: 63 times

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Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Cardiovascular, Endocrine, Hematologic, Pulmonary and Renal Considerations: Executive Summary.

Rahul Nanchal, Ram Subramanian, Constantine J Karvellas, Steven M Hollenberg, William J Peppard, Kai Singbartl, Jonathon Truwit, Ali H Al-Khafaji, Alley J Killian, Mustafa Alquraini, Khalil Alshammari, Fayez Alshamsi, Emilie Belley-Cote, Rodrigo Cartin-Ceba, Joanna C Dionne, Dragos M Galusca, David T Huang, Robert C Hyzy, Mats Junek, Prem Kandiah, Gagan Kumar, Rebecca L Morgan, Peter E Morris, Jody C Olson, Rita Sieracki, Randolph Steadman, Beth Taylor, Waleed Alhazzani,

Crit Care Med (Critical care medicine)
[2020, 48(3):415-419]

Cited: 0 times

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Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Cardiovascular, Endocrine, Hematologic, Pulmonary, and Renal Considerations.

Rahul Nanchal, Ram Subramanian, Constantine J Karvellas, Steven M Hollenberg, William J Peppard, Kai Singbartl, Jonathon Truwit, Ali H Al-Khafaji, Alley J Killian, Mustafa Alquraini, Khalil Alshammari, Fayez Alshamsi, Emilie Belley-Cote, Rodrigo Cartin-Ceba, Joanna C Dionne, Dragos M Galusca, David T Huang, Robert C Hyzy, Mats Junek, Prem Kandiah, Gagan Kumar, Rebecca L Morgan, Peter E Morris, Jody C Olson, Rita Sieracki, Randolph Steadman, Beth Taylor, Waleed Alhazzani,

<h4>Objectives</h4>To develop evidence-based recommendations for clinicians caring for adults with acute or acute on chronic liver failure in the ICU.<h4>Design</h4>The guideline panel comprised 29 members with expertise in aspects of care of the critically ill patient with liver failure and/or methodology. The Society of Critical Care Medicine standard operating procedures ... Read more >>

Crit Care Med (Critical care medicine)
[2020, 48(3):e173-e191]

Cited: 2 times

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Diabetes and Mortality in Acute Coronary Syndrome: Findings from the Gulf COAST Registry.

Abdulla Shehab, Akshaya Srikanth Bhagavathula, Khalid Al-Rasadi, Fayez Alshamsi, Juma Al Kaab, Khalid Bin Thani, Ridha Mustafa,

<h4>Background</h4>The prevalence of traditional risk factors such as diabetes mellitus (DM) and obesity are increasing in patients with acute coronary syndrome (ACS). Furthermore, outcomes after ACS are worse in patients with DM. The high prevalence of DM and an early age at onset of ACS have been described in prior ... Read more >>

Curr Vasc Pharmacol (Current vascular pharmacology)
[2020, 18(1):68-76]

Cited: 2 times

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Extracorporeal liver support in patients with liver failure: a systematic review and meta-analysis of randomized trials.

Fayez Alshamsi, Khalil Alshammari, Emilie Belley-Cote, Joanna Dionne, Talal Albrahim, Budoor Albudoor, Mona Ismail, Bandar Al-Judaibi, Bandar Baw, Ram M Subramanian, Randolph Steadman, Dragos Galusca, David T Huang, Rahul Nanchal, Mustafa Al Quraini, Yuhong Yuan, Waleed Alhazzani, ,

<h4>Purpose</h4>Acute liver failure (ALF) and acute on chronic liver failure (ACLF) are associated with significant mortality and morbidity. Extracorporeal liver support (ECLS) devices have been used as a bridge to liver transplant; however, the efficacy and safety of ECLS are unclear. We conducted a systematic review and meta-analysis of randomized ... Read more >>

Intensive Care Med (Intensive care medicine)
[2020, 46(1):1-16]

Cited: 10 times

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The PROTROPIC feasibility study: prognostic value of elevated troponins in critical illness.

Emilie P Belley-Cote, Richard P Whitlock, Diana V Ulic, Kimia Honarmand, Abubaker Khalifa, Graham R McClure, Andrew Gibson, Fayez Alshamsi, Frederick D'Aragon, Bram Rochwerg, Erick Duan, Nevena Savija, Tim Karachi, François Lamontagne, Peter Kavsak, Deborah J Cook,

<h4>Purpose</h4>Elevated cardiac troponin concentrations in people with critical illness are associated with an increased risk of death. We aimed to assess the feasibility of a larger study to ascertain the utility of cardiac troponin as a prognostic tool for mortality in critically ill patients.<h4>Methods</h4>Patients admitted to participating intensive care units ... Read more >>

Can J Anaesth (Canadian journal of anaesthesia = Journal canadien d'anesthesie)
[2019, 66(6):648-657]

Cited: 0 times

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Provision of renal care for patients with end stage kidney disease in persistent vegetative state, in United Arab Emirates: a national survey of renal physicians.

Fayez Ebrahim Alshamsi, Ahmed Chaaban, Mona Alrukhaimi, Bassam Bernieh, Omran Bakoush,

Patients with end stage kidney disease (ESKD) with severely impaired cognitive function have no survival benefit from dialysis. We therefore undertook a survey to explore the renal physicians' practices of withholding and withdrawal of dialysis treatment in vegetative state patients in the United Arab Emirates (UAE). A cross sectional survey ... Read more >>

Libyan J Med (The Libyan journal of medicine)
[2018, 13(1):1490610]

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Furosemide and Albumin for Diuresis of Edema (FADE): A parallel-group, blinded, pilot randomized controlled trial.

Simon J W Oczkowski, Lisa Klotz, Ian Mazzetti, Fayez Alshamsi, Mei Lin Chen, Gary Foster, Maureen O Meade, Cindy Hamielec,

<h4>Purpose</h4>To assess the feasibility of a trial evaluating whether hyperoncotic albumin, in addition to diuretics, improves diuresis and facilitates liberation from mechanical ventilation in critically ill adults.<h4>Materials and methods</h4>We randomized 46 hemodynamically stable patients with hypoalbuminemia, prescribed diuretics by treating clinicians, to receive 100 mL of 25% albumin or 0.9% saline ... Read more >>

J Crit Care (Journal of critical care)
[2018, 48:462-467]

Cited: 4 times

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Correction to: Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials.

Waleed Alhazzani, Fayez Alshamsi, Emilie Belley-Cote, Diane Heels-Ansdell, Romina Brignardello-Petersen, Mustafa Alquraini, Anders Perner, Morten Hylander Møller, Mette Krag, Saleh Almenawer, Bram Rochwerg, Joanna Dionne, Roman Jaeschke, Mohammed Alshahrani, Adam Deane, Dan Perri, Lehana Thebane, Awad Al-Omari, Simon Finfer, Deborah Cook, Gordon Guyatt,

Owing to an oversight by the authors, all the figures in the last column of Table 2 (upper section: Number needed to treat; lower section: Number needed to harm) in this article were given without the final digit 0 and are thus 10 times too small. ... Read more >>

Intensive Care Med (Intensive care medicine)
[2018, 44(2):277-278]

Cited: 0 times

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Extracorporeal membrane oxygenation for severe Middle East respiratory syndrome coronavirus.

Mohammed S Alshahrani, Anees Sindi, Fayez Alshamsi, Awad Al-Omari, Mohamed El Tahan, Bayan Alahmadi, Ahmed Zein, Naif Khatani, Fahad Al-Hameed, Sultan Alamri, Mohammed Abdelzaher, Amenah Alghamdi, Faisal Alfousan, Adel Tash, Wail Tashkandi, Rajaa Alraddadi, Kim Lewis, Mohammed Badawee, Yaseen M Arabi, Eddy Fan, Waleed Alhazzani,

BACKGROUND:Middle East respiratory syndrome (MERS) is caused by a coronavirus (MERS-CoV) and is characterized by hypoxemic respiratory failure. The objective of this study is to compare the outcomes of MERS-CoV patients before and after the availability of extracorporeal membrane oxygenation (ECMO) as a rescue therapy in severely hypoxemic patients who ... Read more >>

Ann Intensive Care (Annals of intensive care)
[2018, 8(1):3]

Cited: 62 times

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Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials.

Waleed Alhazzani, Fayez Alshamsi, Emilie Belley-Cote, Diane Heels-Ansdell, Romina Brignardello-Petersen, Mustafa Alquraini, Anders Perner, Morten Hylander Møller, Mette Krag, Saleh Almenawer, Bram Rochwerg, Joanna Dionne, Roman Jaeschke, Mohammed Alshahrani, Adam Deane, Dan Perri, Lehana Thebane, Awad Al-Omari, Simon Finfer, Deborah Cook, Gordon Guyatt,

PURPOSE:Stress ulcer prophylaxis (SUP) is commonly prescribed in the intensive care unit. However, data from systematic reviews and conventional meta-analyses are limited by imprecision and restricted to direct comparisons. We conducted a network meta-analysis of randomized clinical trials (RCTs) to examine the safety and efficacy of drugs available for SUP ... Read more >>

Intensive Care Med (Intensive care medicine)
[2018, 44(1):1-11]

Cited: 33 times

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Atraumatic versus conventional lumbar puncture needles: a systematic review and meta-analysis.

Siddharth Nath, Alex Koziarz, Jetan H Badhiwala, Waleed Alhazzani, Roman Jaeschke, Sunjay Sharma, Laura Banfield, Ashkan Shoamanesh, Sheila Singh, Farshad Nassiri, Wieslaw Oczkowski, Emilie Belley-Côté, Ray Truant, Kesava Reddy, Maureen O Meade, Forough Farrokhyar, Malgorzata M Bala, Fayez Alshamsi, Mette Krag, Itziar Etxeandia-Ikobaltzeta, Regina Kunz, Osamu Nishida, Charles Matouk, Magdy Selim, Andrew Rhodes, Gregory Hawryluk, Saleh A Almenawer,

BACKGROUND:Atraumatic needles have been proposed to lower complication rates after lumbar puncture. However, several surveys indicate that clinical adoption of these needles remains poor. We did a systematic review and meta-analysis to compare patient outcomes after lumbar puncture with atraumatic needles and conventional needles. METHODS:In this systematic review and meta-analysis, ... Read more >>

Lancet (Lancet (London, England))
[2018, 391(10126):1197-1204]

Cited: 21 times

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Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis.

Waleed Alhazzani, Gordon Guyatt, Mohammed Alshahrani, Adam M Deane, John C Marshall, Richard Hall, John Muscedere, Shane W English, François Lauzier, Lehana Thabane, Yaseen M Arabi, Tim Karachi, Bram Rochwerg, Simon Finfer, Nick Daneman, Fayez Alshamsi, Nicole Zytaruk, Diane Heel-Ansdell, Deborah Cook, ,

<h4>Introduction</h4>A decreased frequency of upper gastrointestinal bleeding and a possible association of proton pump inhibitor use with Clostridium difficile and ventilator-associated pneumonia have raised concerns recently. The Reevaluating the Inhibition of Stress Erosions Pilot Trial determined the feasibility of undertaking a larger trial investigating the efficacy and safety of withholding ... Read more >>

Crit Care Med (Critical care medicine)
[2017, 45(7):1121-1129]

Cited: 32 times

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Sucralfate versus histamine 2 receptor antagonists for stress ulcer prophylaxis in adult critically ill patients: A meta-analysis and trial sequential analysis of randomized trials.

Mustafa Alquraini, Fayez Alshamsi, Morten Hylander Møller, Emilie Belley-Cote, Saleh Almenawer, Roman Jaeschke, Robert MacLaren, Waleed Alhazzani,

<h4>Purpose</h4>To determine the impact of using sucralfate versus H2RAs for SUP on patient important outcomes.<h4>Materials and methods</h4>We searched CENTRAL, MEDLINE, EMBASE, ACPJC, clinical trials registries, and conference proceedings through June 2016 for randomized controlled trials (RCTs) comparing sucralfate to H2RAs for SUP in adult critically ill patients.<h4>Results</h4>21 RCTs enrolling 3121 ... Read more >>

J Crit Care (Journal of critical care)
[2017, 40:21-30]

Cited: 5 times

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The Deferred Consent Model in a Prospective Observational Study Evaluating Myocardial Injury in the Intensive Care Unit.

Kimia Honarmand, Emilie P Belley-Cote, Diana Ulic, Abubaker Khalifa, Andrew Gibson, Graham McClure, Nevena Savija, Fayez Alshamsi, Frederick D'Aragon, Bram Rochwerg, Erick H Duan, Tim Karachi, François Lamontagne, P J Devereaux, Richard P Whitlock, Deborah J Cook,

<h4>Background</h4>Informed consent is a hallmark of ethical clinical research. An inherent challenge in critical care research is obtaining consent when patients lack decision-making capacity. One solution is deferred consent, which is often used for studies that are low risk or involve emergency interventions. Our objective was to describe a deferred ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2018, 33(8):475-480]

Cited: 5 times

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The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials.

Kim Lewis, Zuhoor Alqahtani, Lauralyn Mcintyre, Saleh Almenawer, Fayez Alshamsi, Andrew Rhodes, Laura Evans, Derek C Angus, Waleed Alhazzani,

<h4>Background</h4>Intolerance to enteral nutrition is common in critically ill adults, and may result in significant morbidity including ileus, abdominal distension, vomiting and potential aspiration events. Prokinetic agents are prescribed to improve gastric emptying. However, the efficacy and safety of these agents in critically ill patients is not well-defined. Therefore, we ... Read more >>

Crit Care (Critical care (London, England))
[2016, 20(1):259]

Cited: 32 times

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