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Author Fahad Quhal

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Choosing the Most Efficacious and Safe Oral Treatment for Idiopathic Overactive Bladder: A Systematic Review and Network Meta-analysis.

Hadi Mostafaei, Hanieh Salehi-Pourmehr, Sandra Jilch, Greta Lisa Carlin, Keiichiro Mori, Fahad Quhal, Benjamin Pradere, Nico C Grossmann, Ekaterina Laukhtina, Victor M Schuettfort, Abdulmajeed Aydh, Reza Sari Motlagh, Frederik König, Claus G Roehrborn, Satoshi Katayama, Pawel Rajwa, Sakineh Hajebrahimi, Shahrokh F Shariat,

The choice of the most efficacious drug for patients with idiopathic overactive bladder (IOAB) remains challenging. The aim of this network meta-analysis was to determine the most efficacious oral antimuscarinic or β-adrenoceptor agonist accounting for adverse events for the management of IOAB. A comprehensive electronic search was done in MEDLINE, ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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The Value of Preoperative Plasma VEGF Levels in Urothelial Carcinoma of the Bladder Treated with Radical Cystectomy.

Keiichiro Mori, Victor M Schuettfort, Satoshi Katayama, Ekaterina Laukhtina, Benjamin Pradere, Fahad Quhal, Reza Sari Motlagh, Hadi Mostafaei, Nico C Grossmann, Pawel Rajwa, Frederik König, Abdulmajeed Aydh, Francesco Soria, Marco Moschini, Pierre I Karakiewicz, Yair Lotan, Douglas Scherr, Martin Haydter, Peter Nyirady, Jeremy Y C Teoh, Shin Egawa, Eva Compérat, Shahrokh F Shariat,

<h4>Background</h4>Elevated preoperative plasma levels of the angiogenesis-related marker VEGF have been associated with worse oncological outcomes in various malignancies.<h4>Objective</h4>To investigate the predictive/prognostic role of VEGF in patients with urothelial carcinoma of the bladder (UCB) treated with radical cystectomy (RC).<h4>Design, setting, and participants</h4>VEGF plasma levels were measured preoperatively in 1036 patients ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Adjuvant therapy with tyrosine kinase inhibitors for localized and locally advanced renal cell carcinoma: an updated systematic review and meta-analysis.

Ekaterina Laukhtina, Fahad Quhal, Keiichiro Mori, Reza Sari Motlagh, Benjamin Pradere, Victor M Schuettfort, Hadi Mostafaei, Satoshi Katayama, Nico С Grossmann, Pawel Rajwa, Irene Resch, Dmitry Enikeev, Pierre I Karakiewicz, Shahrokh F Shariat, Manuela Schmidinger,

<h4>Purpose</h4>Tyrosine kinase inhibitors (TKIs) have been widely used in the management of patients with metastatic renal cell carcinoma (RCC). However, the use of systemic therapies in the adjuvant setting of localized and locally advanced RCC has shown conflicting results across the literature. Therefore, we aimed to conduct an updated systematic ... Read more >>

Urol Oncol (Urologic oncology)
[2021, :]

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Salvage Radical Prostatectomy for Radio-Recurrent Prostate Cancer: An Updated Systematic Review of Oncologic, Histopathologic and Functional Outcomes and Predictors of Good Response.

Bernhard Grubmüller, Victoria Jahrreiss, Stephan Brönimann, Fahad Quhal, Keiichiro Mori, Axel Heidenreich, Alberto Briganti, Derya Tilki, Shahrokh F Shariat,

A valid treatment option for recurrence after definite radiotherapy (RT) for localized prostate cancer (PC) is salvage radical prostatectomy (SRP). However, data on SRP are scarce, possibly resulting in an underutilization. A systematic review was performed using MEDLINE (Pubmed), Embase, and Web of Science databases including studies published between January ... Read more >>

Curr Oncol (Current oncology (Toronto, Ont.))
[2021, 28(4):2881-2892]

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Androgen receptor axis-targeted agents for non-metastatic castration-resistant prostate cancer impact on overall survival and safety profile: an updated systematic review and meta-analysis.

Keiichiro Mori, Fahad Quhal, Satoshi Katayama, Hadi Mostafaei, Ekaterina Laukhtina, Victor M Schuettfort, Reza Sari Motlagh, Nico C Grossmann, Pawel Rajwa, Guillaume Ploussard, Alberto Briganti, Takahiro Kimura, Shin Egawa, Rocco Papalia, Diego M Carrion, Cristian Fiori, Shahrokh F Shariat, Francesco Esperto, Benjamin Pradere,

<h4>Introduction</h4>The management of non-metastatic castration-resistant prostate cancer (nmCRPC) has undergone a paradigm shift with the development of androgen receptor axis-targeted (ARAT) agents. The updated results with final overall survival (OS) data of the phase III PROSPER, SPARTAN, and ARAMIS trials have recently been reported. Therefore, we performed an updated meta-analysis ... Read more >>

Minerva Urol Nephrol (Minerva urology and nephrology)
[2021, :]

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The Efficacy and Safety of Relugolix Compared with Degarelix in Advanced Prostate Cancer Patients: A Network Meta-analysis of Randomized Trials.

Reza Sari Motlagh, Mohammad Abufaraj, Keiichiro Mori, Abdulmajeed Aydh, Pawel Rajwa, Satoshi Katayama, Nico C Grossmann, Ekaterina Laukhtina, Hadi Mostafai, Benjamin Pradere, Fahad Quhal, Pierre I Karakiewicz, Dmitry V Enikeev, Shahrokh F Shariat,

<h4>Context</h4>Degarelix is associated with high rates of injection site reaction. The US Food and Drug Administration approved relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, for the treatment of advanced prostate cancer patients.<h4>Objective</h4>This systematic review and network meta-analysis aimed to compare the efficacy and safety of relugolix versus degarelix.<h4>Evidence acquisition</h4>A systematic ... Read more >>

Eur Urol Oncol (European urology oncology)
[2021, :]

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Incidence, risk factors and outcomes of urethral recurrence after radical cystectomy for bladder cancer: A systematic review and meta-analysis.

Ekaterina Laukhtina, Keiichiro Mori, David D Andrea, Marco Moschini, Mohammad Abufaraj, Francesco Soria, Andrea Mari, Wojciech Krajewski, Simone Albisinni, Jeremy Yuen-Chun Teoh, Fahad Quhal, Reza Sari Motlagh, Hadi Mostafaei, Satoshi Katayama, Nico С Grossmann, Pawel Rajwa, Dmitry Enikeev, Kristin Zimmermann, Harun Fajkovic, Petr Glybochko, Shahrokh F Shariat, Benjamin Pradere, ,

We aimed to conduct a systematic review and meta-analysis assessing the incidence and risk factors of urethral recurrence (UR) as well as summarizing data on survival outcomes in patients with UR after radical cystectomy (RC) for bladder cancer. The MEDLINE and EMBASE databases were searched in February 2021 for studies ... Read more >>

Urol Oncol (Urologic oncology)
[2021, :]

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Adverse events of systemic immune-based combination therapies in the first-line treatment of patients with metastatic renal cell carcinoma: systematic review and network meta-analysis.

Fahad Quhal, Keiichiro Mori, Mesut Remzi, Harun Fajkovic, Shahrokh F Shariat, Manuela Schmidinger,

<h4>Purpose of review</h4>To compare the safety profiles of systemic immune checkpoint inhibitor-based combination therapies that were evaluated in the first-line setting of the management of patients with advanced or metastatic renal cell carcinoma (mRCC).<h4>Recent findings</h4>Six phase III randomized control trials comparing first-line immune-based combination therapies to sunitinib in previously untreated ... Read more >>

Curr Opin Urol (Current opinion in urology)
[2021, 31(4):332-339]

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Prognostic value of the pre-operative serum albumin to globulin ratio in patients with non-metastatic prostate cancer undergoing radical prostatectomy.

Abdulmajeed Aydh, Keiichiro Mori, David D'Andrea, Reza Sari Motlagh, Mohammad Abufaraj, Benjamin Pradere, Hadi Mostafaei, Ekaterina Laukhtina, Fahad Quhal, Pierre I Karakiewicz, Stefano Luzzago, Alberto Briganti, Quoc-Dien Trinh, Mehdi Kardoust Parizi, Derya Tilki, Dmitry V Enikeev, Shahrokh F Shariat,

<h4>Purpose</h4>To evaluate the potential predictive value of the preoperative serum albumin to globulin ratio (AGR) for oncological outcomes in patients treated with radical prostatectomy (RP) for clinically non-metastatic prostate cancer (PCa).<h4>Methods</h4>Pre-operative AGR was assessed in a multi-institutional cohort of 6041 patients treated with RP. Logistic regression analyses were performed to ... Read more >>

Int J Clin Oncol (International journal of clinical oncology)
[2021, 26(9):1729-1735]

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Prognostic Impact of Preoperative Plasma Levels of Urokinase Plasminogen Activator Proteins on Disease Outcomes after Radical Cystectomy.

Victor M Schuettfort, Benjamin Pradere, David D'Andrea, Nico C Grossmann, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Michael Rink, Pierre I Karakiewicz, Reza Sari Motlagh, Satoshi Katayama, Yair Lotan, Douglas Scherr, Mohammad Abufaraj, Harun Fajkovica, Eva Compérat, Dmitry Enikeev, Shahrokh F Shariat,

<h4>Purpose</h4>We sought to validate the association of plasma levels of urokinase-type plasminogen activator (uPA), its soluble receptor (SuPAR) and its inhibitor (PAI-one) with oncologic outcomes in a large cohort of patients treated with radical cystectomy (RC) for urothelial carcinoma of the bladder (UCB).<h4>Materials and methods</h4>We collected preoperative blood samples from ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001936]

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Systemic therapies for metastatic hormone-sensitive prostate cancer: network meta-analysis.

Keiichiro Mori, Hadi Mostafaei, Reza Sari Motlagh, Benjamin Pradere, Fahad Quhal, Ekaterina Laukhtina, Victor M Schuettfort, Gero Kramer, Mohammad Abufaraj, Pierre I Karakiewicz, Takahiro Kimura, Shin Egawa, Shahrokh F Shariat,

<h4>Objectives</h4>To perform a systematic review and network meta-analysis to compare the efficacy and safety of currently available treatments for the management of metastatic hormone-sensitive prostate cancer (mHSPC), as there has been a paradigm shift with the use of next-generation androgen receptor inhibitors (ARIs) and docetaxel.<h4>Methods</h4>Multiple databases were searched for articles ... Read more >>

BJU Int (BJU international)
[2021, :]

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Prognostic value of the systemic immune-inflammation index in non-muscle invasive bladder cancer.

Satoshi Katayama, Keiichiro Mori, Benjamin Pradere, Ekaterina Laukhtina, Victor M Schuettfort, Fahad Quhal, Reza Sari Motlagh, Hadi Mostafaei, Nico C Grossmann, Pawel Rajwa, Marco Moschini, Romain Mathieu, Mohammad Abufaraj, David D'Andrea, Eva Compérat, Martin Haydter, Shin Egawa, Yasutomo Nasu, Shahrokh F Shariat, ,

<h4>Purpose</h4>We assessed the prognostic value of systemic immune-inflammation index (SII) to refine risk stratification of the heterogeneous spectrum of patients with non-muscle-invasive bladder cancer (NMIBC) METHODS: In this multi-institutional cohort, preoperative blood-based SII was retrospectively assessed in 1117 patients with NMIBC who underwent transurethral resection of bladder (TURB) between 1996 ... Read more >>

World J Urol (World journal of urology)
[2021, :]

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Intracorporeal versus extracorporeal urinary diversion in robot-assisted radical cystectomy: a systematic review and meta-analysis.

Satoshi Katayama, Keiichiro Mori, Benjamin Pradere, Hadi Mostafaei, Victor M Schuettfort, Fahad Quhal, Reza Sari Motlagh, Ekaterina Laukhtina, Marco Moschini, Nico C Grossmann, Yasutomo Nasu, Shahrokh F Shariat, Harun Fajkovic,

This systematic review and meta-analysis aimed to assess and compare the perioperative and oncological outcomes of intracorporeal (ICUD) and extracorporeal (ECUD) urinary diversion following robot-assisted radical cystectomy (RARC). A systematic literature search of articles was performed in PubMed<sup>®</sup>, Web of Science<sup>®</sup>, and Scopus<sup>®</sup> databases according to the Preferred Reporting Items ... Read more >>

Int J Clin Oncol (International journal of clinical oncology)
[2021, 26(9):1587-1599]

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Impact of systemic Immune-inflammation Index on oncologic outcomes in patients treated with radical prostatectomy for clinically nonmetastatic prostate cancer.

Pawel Rajwa, Victor M Schuettfort, David D'Andrea, Fahad Quhal, Keiichiro Mori, Satoshi Katayama, Ekaterina Laukhtina, Benjamin Pradere, Reza Sari Motlagh, Hadi Mostafaei, Nico C Grossmann, Nicolai Huebner, Andreas Aulitzky, Dong-Ho Mun, Alberto Briganti, Pierre I Karakiewicz, Harun Fajkovic, Shahrokh F Shariat,

<h4>Purpose</h4>To evaluate the predictive and prognostic value of the Systemic Immune-inflammation Index (SII) in a large cohort of patients treated with radical prostatectomy (RP) for clinically non-metastatic prostate cancer (PCa).<h4>Methods</h4>We retrospectively analyzed our multicenter database comprising 6,039 consecutive patients. The optimal preoperative SII cut-off value was assessed with the Youden ... Read more >>

Urol Oncol (Urologic oncology)
[2021, :]

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Differences in oncological and toxicity outcomes between programmed cell death-1 and programmed cell death ligand-1 inhibitors in metastatic renal cell carcinoma: A systematic review and meta-analysis.

Keiichiro Mori, Benjamin Pradere, Fahad Quhal, Satoshi Katayama, Hadi Mostafaei, Ekaterina Laukhtina, Victor M Schuettfort, David D'Andrea, Shin Egawa, Karim Bensalah, Manuela Schmidinger, Thomas Powles, Shahrokh F Shariat,

<h4>Background</h4>The programmed cell death ligand-1 (PD-L1)/programmed cell death-1 (PD-1) pathway is important in metastatic renal cell carcinoma (mRCC). However, some dissimilarities between anti-PD-1 and anti-PD-L1 inhibitors have emerged. We aimed to assess differences between anti-PD-1 and anti-PD-L1 combination immunotherapies as first-line treatments in mRCC patients.<h4>Methods</h4>Multiple databases (PubMed, Web of Science, ... Read more >>

Cancer Treat Rev (Cancer treatment reviews)
[2021, 99:102242]

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Impact of the preoperative modified glasgow prognostic score on disease outcome after radical cystectomy for urothelial carcinoma of the bladder.

Victor M Schuettfort, Kilian Gust, David D'Andrea, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Michael Rink, Mohammad Abufaraj, Pierre I Karakiewicz, Stefano Luzzago, Morgan Rouprêt, Dmitry Enikeev, Kristin Zimmermann, Marina Deuker, Marco Moschini, Reza Sari Motlagh, Nico C Grossmann, Satoshi Katayama, Benjamin Pradere, Shahrokh F Shariat,

<h4>Background</h4>To investigate the predictive and prognostic value of the preoperative modified Glasgow Prognostic Score (mGPS) in patients with urothelial carcinoma of the bladder (UCB) treated with radical cystectomy (RC).<h4>Methods</h4>We conducted a retrospective analysis of an established multicenter database consisting of 4,335 patients who were treated with RC +/- adjuvant chemotherapy ... Read more >>

Minerva Urol Nephrol (Minerva urology and nephrology)
[2021, :]

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The role of lymph node dissection in salvage radical prostatectomy for patients with radiation recurrent prostate cancer.

Fahad Quhal, Pawel Rajwa, Keiichiro Mori, Ekaterina Laukhtina, Nico C Grossmann, Victor M Schuettfort, Frederik König, Abdulmajeed Aydh, Reza S Motlagh, Satoshi Katayama, Hadi Mostafai, Benjamin Pradere, Giancarlo Marra, Paolo Gontero, Romain Mathieu, Pierre I Karakiewicz, Alberto Briganti, Shahrokh F Shariat, Axel Heidenreich,

<h4>Purpose</h4>To examine the effect of lymph node dissection on the outcomes of patients who underwent salvage radical prostatectomy (SRP).<h4>Material and methods</h4>We retrospectively reviewed data from radiation-recurrent patients with prostate cancer (PCa) who underwent SRP from 2000-2016. None of the patients had clinical lymph node involvement before SRP. The effect of ... Read more >>

Prostate (The Prostate)
[2021, 81(11):765-771]

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Oncologic impact of delaying radical prostatectomy in men with intermediate- and high-risk prostate cancer: a systematic review.

Ekaterina Laukhtina, Reza Sari Motlagh, Keiichiro Mori, Fahad Quhal, Victor M Schuettfort, Hadi Mostafaei, Satoshi Katayama, Nico C Grossmann, Guillaume Ploussard, Pierre I Karakiewicz, Alberto Briganti, Mohammad Abufaraj, Dmitry Enikeev, Benjamin Pradere, Shahrokh F Shariat,

<h4>Purpose</h4>To summarize the available evidence on the survival and pathologic outcomes after deferred radical prostatectomy (RP) in men with intermediate- and high-risk prostate cancer (PCa).<h4>Methods</h4>The PubMed database and Web of Science were searched in November 2020 according to the PRISMA statement. Studies were deemed eligible if they reported the survival ... Read more >>

World J Urol (World journal of urology)
[2021, :]

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Impact of preoperative plasma levels of interleukin 6 and interleukin 6 soluble receptor on disease outcomes after radical cystectomy for bladder cancer.

Victor M Schuettfort, Benjamin Pradere, Quoc-Dien Trinh, David D'Andrea, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Reza Sari Motlagh, Michael Rink, Pierre I Karakiewicz, Piotr Chlosta, Jeremy Yuen-Chun Teoh, Yair Lotan, Douglas Scherr, Mohammad Abufaraj, Marco Moschini, Shahrokh F Shariat,

<h4>Background</h4>Preoperative plasma levels of Interleukin 6 (IL6) and its soluble receptor (IL6sR) have previously been associated with oncologic outcomes in urothelial carcinoma of the bladder (UCB); however, external validation in patients treated with radical cystectomy (RC) for UCB is missing.<h4>Patients/methods</h4>We prospectively collected preoperative plasma from 1,036 consecutive patients at two ... Read more >>

Cancer Immunol Immunother (Cancer immunology, immunotherapy : CII)
[2021, :]

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Reliability of Serial Prostate Magnetic Resonance Imaging to Detect Prostate Cancer Progression During Active Surveillance: A Systematic Review and Meta-analysis.

Pawel Rajwa, Benjamin Pradere, Fahad Quhal, Keiichiro Mori, Ekaterina Laukhtina, Nicolai A Huebner, David D'Andrea, Aleksandra Krzywon, Sung Ryul Shim, Pascal A Baltzer, Raphaële Renard-Penna, Michael S Leapman, Shahrokh F Shariat, Guillaume Ploussard,

<h4>Context</h4>Although magnetic resonance imaging (MRI) is broadly implemented into active surveillance (AS) protocols, data on the reliability of serial MRI in order to help guide follow-up biopsy are inconclusive.<h4>Objective</h4>To assess the diagnostic estimates of serial prostate MRI for prostate cancer (PCa) progression during AS.<h4>Evidence acquisition</h4>We systematically searched PubMed, Scopus, and ... Read more >>

Eur Urol (European urology)
[2021, :]

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Accuracy of Frozen Section Analysis of Urethral and Ureteral Margins During Radical Cystectomy for Bladder Cancer: A Systematic Review and Diagnostic Meta-Analysis.

Ekaterina Laukhtina, Pawel Rajwa, Keiichiro Mori, Marco Moschini, David D'Andrea, Mohammad Abufaraj, Francesco Soria, Andrea Mari, Wojciech Krajewski, Simone Albisinni, Jeremy Yuen-Chun Teoh, Fahad Quhal, Reza Sari Motlagh, Hadi Mostafaei, Satoshi Katayama, Nico C Grossmann, Dmitry Enikeev, Kristin Zimmermann, Harun Fajkovic, Petr Glybochko, Shahrokh F Shariat, Benjamin Pradere, ,

<h4>Context</h4>The question of the ability of frozen section analysis (FSA) to accurately detect malignant pathology intraoperatively has been discussed for many decades.<h4>Objective</h4>We aimed to conduct a systematic review and meta-analysis assessing the diagnostic estimates of FSA of the urethral and ureteral margins in patients treated with radical cystectomy (RC) for ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

Cited: 1 time

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Prognostic Impact of Different Gleason Patterns on Biopsy Within Grade Group 4 Prostate Cancer.

Keiichiro Mori, Vidit Sharma, Eva M Comperat, Shun Sato, Ekaterina Laukhtina, Victor M Schuettfort, Benjamin Pradere, Reza Sari Motlagh, Hadi Mostafaei, Fahad Quhal, Mehdi Kardoust Parizi, Mohammad Abufaraj, Pierre I Karakiewicz, Shin Egawa, Derya Tilki, Stephen A Boorjian, Shahrokh F Shariat,

<h4>Background</h4>Grade group (GG) 4 prostate cancer (PC) is considered a single entity; however, there are questions regarding prognostic heterogeneity. This study assessed the prognostic differences among various Gleason scores (GSs) classified as GG 4 PC on biopsy before radical prostatectomy (RP).<h4>Methods</h4>We conducted a multicenter retrospective study, and a total of ... Read more >>

Ann Surg Oncol (Annals of surgical oncology)
[2021, :]

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Impact of enhanced optical techniques at time of transurethral resection of bladder tumour, with or without single immediate intravesical chemotherapy, on recurrence rate of non-muscle-invasive bladder cancer: a systematic review and network meta-analysis of randomized trials.

Reza Sari Motlagh, Keiichiro Mori, Ekaterina Laukhtina, Abdulmajeed Aydh, Satoshi Katayama, Nico C Grossmann, Hadi Mostafai, Benjamin Pradere, Fahad Quhal, Victor M Schuettfort, Mohammad Reza Roshandel, Pierre I Karakiewicz, Jeremy Teoh, Shahrokh F Shariat, Harun Fajkovic,

<h4>Objective</h4>To assess whether single immediate intravesical chemotherapy (SIIC) adds value to bladder tumour management in combination with novel optical techniques: enhanced transurethral resection of bladder tumour (TURBT).<h4>Methods</h4>A systematic search was performed using the PubMed and Web of Science databases in September 2020 according to the Preferred Reporting Items for Systematic ... Read more >>

BJU Int (BJU international)
[2021, 128(3):280-289]

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Adverse events of the second-line treatment for patients with locally advanced or metastatic urothelial carcinoma of the bladder: network meta-analysis.

Ekaterina Laukhtina, Keiichiro Mori, Hadi Mostafaei, Axel S Merseburger, Peter Nyirady, Marco Moschini, Fahad Quhal, Victor M Schuettfort, Benjamin Pradere, Reza Sari Motlagh, Dmitry Enikeev, Shahrokh F Shariat, European Association Of Urology-Young Academic Urologists Eau-Yau Urothelial Carcinoma Working Group,

<b>Aim:</b> We aimed to compare the mortality rates related to adverse events (AEs) and discontinuation of treatment due to toxicity as well as all AEs of currently used regimens of second-line treatment strategies for advanced or metastatic urothelial carcinoma of the bladder. <b>Methods:</b> The MEDLINE and EMBASE databases were searched ... Read more >>

Immunotherapy (Immunotherapy)
[2021, 13(11):917-929]

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Accuracy and Clinical Utility of a Tumor Grade- and Stage-based Predictive Model in Localized Upper Tract Urothelial Carcinoma.

Satoshi Katayama, Keiichiro Mori, Victor M Schuettfort, Benjamin Pradere, Hadi Mostafaei, Fahad Quhal, Pawel Rajwa, Reza Sari Motlagh, Ekaterina Laukhtina, Marco Moschini, Nico C Grossmann, Motoo Araki, Jeremy Yuen-Chun Teoh, Morgan Rouprêt, Vitaly Margulis, Dmitry Enikeev, Pierre I Karakiewicz, Mohammad Abufaraj, Eva Compérat, Yasutomo Nasu, Shahrokh F Shariat,

<h4>Background</h4>Among various clinicopathologic factors used to identify low-risk upper tract urothelial carcinoma (UTUC), tumor grade and stage are of utmost importance. The clinical value added by inclusion of other risk factors remains unproven.<h4>Objective</h4>To assess the performance of a tumor grade- and stage-based (GS) model to identify patients with UTUC for ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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