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Author Fabien Rallu

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Oropharyngeal Carriage of Kingella kingae and Transient Synovitis of the Hip in Young Children: A Case-Control Study.

Jocelyn Gravel, Sergio Manzano, Marie-Lyne Nault, Émilie Vallières, Fabien Rallu, Christian Renaud,

<h4>Background</h4>Transient synovitis of the hip affects mostly preschool children, and its etiology is unknown. Kingella kingae has been identified recently as a common etiologic agent of osteoarticular infections (OAI) in young children and could potentially be associated to transient synovitis of the hip. The main objective of this study was ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, Publish Ahead of Print:]

Cited: 0 times

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Mid-trimester microbial invasion of the amniotic cavity and the risk of preterm birth.

Amélie Tétu, Paul Guerby, Fabien Rallu, Louise Duperron, Valérie Morin, Emmanuel Bujold,

<h4>Objective</h4>To evaluate the rate of mid-trimester microbial invasion of the amniotic cavity (MIAC) in asymptomatic women and its association with preterm birth.<h4>Study design</h4>This is a prospective cohort study of asymptomatic women undergoing mid-trimester amniocentesis for genetic testing between 14 and 24 weeks of gestation. For each participant, a sample of amniotic ... Read more >>

J Matern Fetal Neonatal Med (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2020, :1-4]

Cited: 0 times

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Impact of the adolescent pertussis booster dose on the incidence of pertussis in British Columbia and Quebec, Canada.

Nicholas Brousseau, Danuta M Skowronski, David Bellemare, Rachid Amini, Yayuk Joffres, Quinten Clarke, Caroline Quach, Fabien Rallu, Linda Hoang, Gaston De Serres,

Impact of an adolescent tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine program was assessed in the provinces of British Columbia and Quebec, Canada. In both provinces, the Tdap booster has been in place since 2004, targeting Grade 9 students (14-15-years-of-age). Incidence rate ratios (IRRs) standardizing notification rates ... Read more >>

Vaccine (Vaccine)
[2020, 38(3):427-432]

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Multiplex Polymerase Chain Reaction Panel for Suspected Pertussis: What About a Positive Mycoplasma pneumoniae Result?

Michaël Desjardins, Paméla Doyon-Plourde, Sarah Mousseau, Daniela Iachimov, Fabien Rallu, Caroline Quach,

BACKGROUND:The use of bacterial multiplex polymerase chain reaction (PCR) in children with suspected pertussis sometimes yields unexpected positive results for Mycoplasma pneumoniae. We aimed to evaluate the clinical significance of positive M. pneumoniae results in this population. METHODS:Retrospective cohort of consecutive patients with suspected pertussis tested with a bacterial multiplex ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2019, 38(10):1015-1019]

Cited: 0 times

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THE EPIDEMIOLOGY AND CLINICAL FEATURES OF SEPTIC ARTHRITIS CASES SECONDARY TO KINGELLA KINGAE IN COMPARISON TO SEPTIC ARTHRITIS FROM OTHER PATHOGENS.

Jessica ElBared, Émilie Vallières, Christian Renaud, Jocelyn Gravel, Caroline Chartrand, Fabien Rallu, YongMu Ouyang,

AbstractBACKGROUNDIn Europe (Kk) is considered as a significant pathogen in osteoarticular infections (OAI) in young children. Some authors suggest that a significant portion of ‘culture negative septic arthritis’ may be secondary to the inability to isolate using conventional methods. However, its pathogenic role and prevalence remain controversial in North ... Read more >>

Paediatr Child Health (Paediatrics & child health)
[2018, 23(Suppl 1):e45-e45]

Cited: 0 times

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Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy for Rapid Identification of Non-Fermenting Gram-Negative Bacilli Isolated from Patients with Cystic Fibrosis

Emilie Vallieres, Caroline Quach, Lisa Lam, Fabien Rallu, Michele Langella, Jacqueline Sedman, Martin Raymond, Pierre Lebel, Ashraf Ismail,

Abstract <h4>Background</h4> Chronic respiratory infections with non-fermenting Gram-negative bacilli are a key feature of cystic fibrosis (CF). For microbiology laboratories, rapid and accurate identification of these bacteria is often challenging and labor intensive. This study was undertaken to evaluate whether attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy could rapidly ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2017, 4(Suppl 1):S592-S592]

Cited: 0 times

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Group A streptococcal primary peritonitis in a healthy girl.

Maryline Chomton, Guillaume Emeriaud, Philippe Bidet, Fabien Rallu, Philippe Ovetchkine, Jean Gaschignard,

J Paediatr Child Health (Journal of paediatrics and child health)
[2017, 53(6):615-616]

Cited: 1 time

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Clinical and Microbiological Characteristics of Invasive Group A Streptococcal Infections Before and After Implementation of a Universal Varicella Vaccine Program.

Julie Frère, Philippe Bidet, Bruce Tapiéro, Fabien Rallu, Philippe Minodier, Stephane Bonacorsi, Edouard Bingen, Philippe Ovetchkine,

Since the introduction of the varicella vaccine to the routine immunization schedule, we have observed a 70% reduction in the rate of varicella-associated invasive group A streptococcal infections (IGASI). In the mean time, the clinical presentation of IGASI and microbiological characteristics of GAS strains have changed significantly. ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2016, 62(1):75-77]

Cited: 3 times

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Invasive group A Streptococcus disease in French-Canadian children is not associated with a defect in MyD88/IRAK4-pathway.

Isabel Fernandez, Rose-Marie Brito, Philippe Bidet, Fabien Rallu, Celine Laferrière, Philippe Ovetchkine, Francoise Le Deist,

<h4>Background</h4>Beta-hemolytic Group A Streptococcus invasive disease (iGASd) has been subject to intense research since its re-emergence in the late 1980s. In Quebec, an increase in the number of severe iGASd cases has recently been observed. Because of the inter-individual variability in the severity of iGASd, a hereditary predisposition to invasive ... Read more >>

Allergy Asthma Clin Immunol (Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology)
[2014, 10(1):9]

Cited: 3 times

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First documented case of human infection with ovine Shiga-toxin-producing Escherichia coli serotype O52:H45.

Sadjia Bekal, Danielle Ramsay, Fabien Rallu, Pierre Pilon, Matthew Gilmour, Roger Johnson, Cécile Tremblay,

We report a concurrent case of infection with non-O157 Shiga-toxin-producing Escherichia coli (STEC) strain in an 8-month-old child. Laboratory and epidemiological investigations indicated child exposure to contaminated sheep meat following the Muslim feast of sacrifice (Eid al-Adha). Microbiological and molecular typing confirmed that the ovine strain O52:H45 (stx1+, eae-, hlyA-) ... Read more >>

Can J Microbiol (Canadian journal of microbiology)
[2014, 60(6):417-418]

Cited: 2 times

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The origin of Fusobacterium nucleatum involved in intra-amniotic infection and preterm birth.

Simon Gauthier, Amélie Tétu, Eric Himaya, Marianne Morand, Fatiha Chandad, Fabien Rallu, Emmanuel Bujold,

<h4>Objective</h4>To evaluate the potential oral origin of Fusobacterium nucleatum found in amniotic fluid of women at high risk of preterm birth.<h4>Methods</h4>A transversal study nested into a cohort study of women with preterm labor and/or preterm premature rupture of membranes was undergone. Women with the presence of F. nucleatum in the ... Read more >>

J Matern Fetal Neonatal Med (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2011, 24(11):1329-1332]

Cited: 15 times

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Invasive pneumococcal disease after implementation of a reduced three-dose pneumococcal conjugate vaccine program: a pediatric tertiary care center experience.

Pierre Alex Crisinel, Isabelle Chevalier, Fabien Rallu, Bruce Tapiero, Valérie Lamarre, Roseline Thibault, Philippe Ovetchkine,

Following the implementation of a government-sponsored reduced three-dose (2 + 1) heptavalent conjugate pneumococcal vaccine (PCV7) program, we report a 61.4% decrease in the number of cases of invasive pneumococcal diseases (IPD) treated at our institution. Four years after the implementation of the three-dose reduced vaccine program, only 7.4% of ... Read more >>

Eur J Pediatr (European journal of pediatrics)
[2010, 169(11):1311-1315]

Cited: 11 times

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Bacteriology of amniotic fluid in women with suspected cervical insufficiency.

Emmanuel Bujold, Anne-Maude Morency, Fabien Rallu, Suzanne Ferland, Amélie Tétu, Louise Duperron, François Audibert, Céline Laferrière,

<h4>Objective</h4>To determine the prevalence of mid-trimester microbial invasion of the amniotic cavity (MIAC) in women with suspected cervical insufficiency.<h4>Methods</h4>A prospective observational cohort study was performed in women with suspected cervical insufficiency and visible fetal membranes who were undergoing amniocentesis to rule out MIAC between 16 and 26 weeks of gestation. ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2008, 30(10):882-887]

Cited: 27 times

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Clinical and microbiologic characteristics of group A streptococcal necrotizing fasciitis in children.

Philippe Minodier, Philippe Bidet, Fabien Rallu, Bruce Tapiero, Edouard Bingen, Philippe Ovetchkine,

An increase in the incidence of Group A streptococcal necrotizing fasciitis has recently been observed in Montréal, Canada. Clinical features of children hospitalized for invasive Group A streptococcal infections and various virulence factor genes of the bacteria were concomitantly analyzed. It was determined that varicella and presence of speC gene ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2009, 28(6):541-543]

Cited: 15 times

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Epidemiological, biochemical and antimicrobial susceptibility characteristics of Streptococcus pseudoporcinus isolated in Quebec, Canada, from 1997 to 2006.

Christiane Gaudreau, Esther Simoneau, Olivia Labrecque, Robert A Laurence, Céline Laferrière, Mark Miller, Lélia Raynal, Fabien Rallu,

From 1997 to 2006, in the province of Quebec, Canada, 15 isolates of Streptococcus pseudoporcinus from 1 urine and 14 vaginorectal cultures were recovered from the genitourinary tract of pregnant women. All these women originated from the Caribbean or sub-Saharan Africa (P=0.00045 compared with a suitable control group). The S. ... Read more >>

J Med Microbiol (Journal of medical microbiology)
[2007, 56(Pt 12):1620-1624]

Cited: 16 times

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Eradication of intra-amniotic Streptococcus mutans in a woman with a short cervix.

Anne-Maude Morency, Fabien Rallu, Céline Laferrière, Emmanuel Bujold,

<h4>Background</h4>Microbial invasion of the amniotic cavity (MIAC) remains an important pathogenetic factor in preterm births. Although most MIACs seem to originate in vaginal microflora, other reservoirs such as the oral microflora have been suggested.<h4>Case</h4>We report a case of successful eradication of Streptococcus mutans (a bacterium generally found in dental plaque) ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2006, 28(10):898-902]

Cited: 8 times

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Invasion of the amniotic cavity by an uncultured bacterium, a Gram-positive coccus.

Fabien Rallu, Anne-Maude Morency, Céline Laferrière, Emmanuel Bujold,

J Matern Fetal Neonatal Med (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2007, 20(2):185-187]

Cited: 3 times

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Sensitivities of antigen detection and PCR assays greatly increased compared to that of the standard culture method for screening for group B streptococcus carriage in pregnant women.

Fabien Rallu, Peter Barriga, Carole Scrivo, Valérie Martel-Laferrière, Céline Laferrière,

Group B streptococcus (GBS) is a major cause of serious infections in neonates. The 2002 revised guidelines of the Centers for Disease Control and Prevention (CDC) for the prevention of perinatal GBS disease recommend that all pregnant women be screened for GBS carriage at between 35 and 37 weeks of ... Read more >>

J Clin Microbiol (Journal of clinical microbiology)
[2006, 44(3):725-728]

Cited: 41 times

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RNase HI overproduction is required for efficient full-length RNA synthesis in the absence of topoisomerase I in Escherichia coli.

Imad Baaklini, Chadi Hraiky, Fabien Rallu, Yuk-Ching Tse-Dinh, Marc Drolet,

It has long been known that Escherichia coli cells deprived of topoisomerase I (topA null mutants) do not grow. Because mutations reducing DNA gyrase activity and, as a consequence, negative supercoiling, occur to compensate for the loss of topA function, it has been assumed that excessive negative supercoiling is somehow ... Read more >>

Mol Microbiol (Molecular microbiology)
[2004, 54(1):198-211]

Cited: 26 times

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Effects of RNA polymerase modifications on transcription-induced negative supercoiling and associated R-loop formation.

Sonia Broccoli, Fabien Rallu, Patrick Sanscartier, Susana M Cerritelli, Robert J Crouch, Marc Drolet,

Transcription in the absence of topoisomerase I, but in the presence of DNA gyrase, can result in the formation of hypernegatively supercoiled DNA and associated R-loops. In this paper, we have used several strategies to study the effects of elongation/termination properties of RNA polymerase on such transcription-induced supercoiling. Effects on ... Read more >>

Mol Microbiol (Molecular microbiology)
[2004, 52(6):1769-1779]

Cited: 25 times

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The problem of hypernegative supercoiling and R-loop formation in transcription.

Marc Drolet, Sonia Broccoli, Fabien Rallu, Chadi Hraiky, Charles Fortin, Eric Massé, Imad Baaklini,

DNA supercoiling and topoisomerases have long been known to affect transcription initiation. In many studies, topA mutants were used to perturb chromosomal supercoiling. Although such studies clearly revealed that supercoiling could significantly affect gene expression, they did not tell much about the essential function(s) of DNA topoisomerase I, encoded by ... Read more >>

Front Biosci (Frontiers in bioscience : a journal and virtual library)
[2003, 8:d210-21]

Cited: 40 times

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