Full Text Journal Articles by
Author Eva Hadadi

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Efficacy of CD40 agonists is mediated by distinct cDC subsets and subverted by suppressive macrophages.

Aleksandar Murgaski, Máté Kiss, Helena Van Damme, Daliya Kancheva, Isaure Vanmeerbeek, Jiri Keirsse, Eva Hadadi, Jan Brughmans, Sana M Arnouk, Ahmed E I Hamouda, Ayla Debraekeleer, Victor Bosteels, Yvon Elkrim, Louis Boon, Sabine Hoves, Niels Vandamme, Sofie Deschoemaeker, Sophie Janssens, Abhishek D Garg, Greetje Vande Velde, Martina Schmittnaegel, Carola H Ries, Damya Laoui,

Agonistic αCD40 therapy has been shown to inhibit cancer progression in only a fraction of patients. Understanding the cancer cell-intrinsic and microenvironmental determinants of αCD40 therapy response is therefore crucial to identify responsive patient populations and design efficient combinatorial treatments. Here, we show that the therapeutic efficacy of αCD40 in ... Read more >>

Cancer Res (Cancer research)
[2022, :CAN-22-0094]

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Heterogeneity and function of macrophages in the breast during homeostasis and cancer.

Eva Hadadi, Sofie Deschoemaeker, Gerard Vicente Venegas, Damya Laoui,

Macrophages are diverse immune cells populating all tissues and adopting a unique tissue-specific identity. Breast macrophages play an essential role in the development and function of the mammary gland over one's lifetime. In the recent years, with the development of fate-mapping, imaging and scRNA-seq technologies we grew a better understanding ... Read more >>

Int Rev Cell Mol Biol (International review of cell and molecular biology)
[2022, 367:149-182]

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