Full Text Journal Articles by
Author Eugenio Martuscelli

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Clinical Features and Management of COVID-19 Associated Hypercoagulability

Gianluca Massaro, Dalgisio Lecis, Eugenio Martuscelli, Gaetano Chiricolo, Giuseppe Massimo Sangiorgi,

Synopsis Covid-19 is an acute respiratory disease of viral origin caused by Sars-Cov2. This disease is associated with a hypercoagulable state resulting in arterial and venous thrombotic events. The latter are more frequent, especially in patients who develop a severe form of the disease and are associated with an increased ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

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COVID-19, Acute Myocardial Injury and Infarction

Armando Del Prete, Francesca Conway, Domenico Giovanni Della Rocca, Giuseppe Biondi-Zoccai, Francesco De Felice, Carmine Musto, Marco Picichè, Eugenio Martuscelli, Andrea Natale, Francesco Versaci,

Synopsis SARS-CoV-2 can affect the cardiovascular system yielding a wide range of complications, including acute myocardial injury. The myocardium can be damaged by direct viral invasion or indirect mechanisms, sustained by systemic inflammation, immune-mediated response and dysregulation of the renin-angiotensin system. Myocardial injury affects about one-quarter of patients with COVID-19, ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

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A thymic hyperplasia-related reversible complete atrioventricular block: When compression is more important than compressor.

Gianluca Massaro, Giuseppe Stifano, Vincenzo Ambrogi, Lucia Anemona, Enrica Giuliana Mariano, Gaetano Chiricolo, Eugenio Martuscelli, Giuseppe Massimo Sangiorgi,

A 19-year-old patient presented for syncope with third-degree AV block (TDAVB) at ECG. A chest-CT showed a thymic mass that could be responsible for TDAVB due to extrinsic vagal nerve compression. Thymectomy led to complete AV block resolution. An extrinsic vagal compression mechanism should be considered among causes of complete ... Read more >>

J Electrocardiol (Journal of electrocardiology)
[2021, 69:68-70]

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Anatomy, Pathophysiology, Molecular Mechanisms, and Clinical Management of Erectile Dysfunction in Patients Affected by Coronary Artery Disease: A Review.

Giuseppe Sangiorgi, Alberto Cereda, Daniela Benedetto, Michela Bonanni, Gaetano Chiricolo, Linda Cota, Eugenio Martuscelli, Francesco Greco,

Erectile dysfunction (ED) has been defined as the inability to attain or maintain penile erection sufficient for successful sexual intercourse. ED carries a notable influence on life quality, with significant implications for family and social relationships. Because atherosclerosis of penile arteries represents one of the most frequent ED causes, patients ... Read more >>

Biomedicines (Biomedicines)
[2021, 9(4):]

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Diagnosis of obstructive coronary artery disease using computed tomography angiography in patients with stable chest pain depending on clinical probability and in clinically important subgroups: meta-analysis of individual patient data.

Robert Haase, Peter Schlattmann, Pascal Gueret, Daniele Andreini, Gianluca Pontone, Hatem Alkadhi, Jörg Hausleiter, Mario J Garcia, Sebastian Leschka, Willem B Meijboom, Elke Zimmermann, Bernhard Gerber, U Joseph Schoepf, Abbas A Shabestari, Bjarne L Nørgaard, Matthijs F L Meijs, Akira Sato, Kristian A Ovrehus, Axel C P Diederichsen, Shona M M Jenkins, Juhani Knuuti, Ashraf Hamdan, Bjørn A Halvorsen, Vladimir Mendoza-Rodriguez, Carlos E Rochitte, Johannes Rixe, Yung Liang Wan, Christoph Langer, Nuno Bettencourt, Eugenio Martuscelli, Said Ghostine, Ronny R Buechel, Konstantin Nikolaou, Hans Mickley, Lin Yang, Zhaqoi Zhang, Marcus Y Chen, David A Halon, Matthias Rief, Kai Sun, Beatrice Hirt-Moch, Hiroyuki Niinuma, Roy P Marcus, Simone Muraglia, Réda Jakamy, Benjamin J Chow, Philipp A Kaufmann, Jean-Claude Tardif, Cesar Nomura, Klaus F Kofoed, Jean-Pierre Laissy, Armin Arbab-Zadeh, Kakuya Kitagawa, Roger Laham, Masahiro Jinzaki, John Hoe, Frank J Rybicki, Arthur Scholte, Narinder Paul, Swee Y Tan, Kunihiro Yoshioka, Robert Röhle, Georg M Schuetz, Sabine Schueler, Maria H Coenen, Viktoria Wieske, Stephan Achenbach, Matthew J Budoff, Michael Laule, David E Newby, Marc Dewey, ,

<h4>Objective</h4>To determine whether coronary computed tomography angiography (CTA) should be performed in patients with any clinical probability of coronary artery disease (CAD), and whether the diagnostic performance differs between subgroups of patients.<h4>Design</h4>Prospectively designed meta-analysis of individual patient data from prospective diagnostic accuracy studies.<h4>Data sources</h4>Medline, Embase, and Web of Science for ... Read more >>

BMJ (BMJ (Clinical research ed.))
[2019, 365:l1945]

Cited: 13 times

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Correction to: Applicability and accuracy of pretest probability calculations implemented in the NICE clinical guideline for decision making about imaging in patients with chest pain of recent onset.

Robert Roehle, Viktoria Wieske, Georg M Schuetz, Pascal Gueret, Daniele Andreini, Willem Bob Meijboom, Gianluca Pontone, Mario Garcia, Hatem Alkadhi, Lily Honoris, Jörg Hausleiter, Nuno Bettencourt, Elke Zimmermann, Sebastian Leschka, Bernhard Gerber, Carlos Rochitte, U Joseph Schoepf, Abbas Arjmand Shabestari, Bjarne Nørgaard, Akira Sato, Juhani Knuuti, Matthijs F L Meijs, Harald Brodoefel, Shona M M Jenkins, Kristian Altern Øvrehus, Axel Cosmus Pyndt Diederichsen, Ashraf Hamdan, Bjørn Arild Halvorsen, Vladimir Mendoza Rodriguez, Yung Liang Wan, Johannes Rixe, Mehraj Sheikh, Christoph Langer, Said Ghostine, Eugenio Martuscelli, Hiroyuki Niinuma, Arthur Scholte, Konstantin Nikolaou, Geir Ulimoen, Zhaoqi Zhang, Hans Mickley, Koen Nieman, Philipp A Kaufmann, Ronny Ralf Buechel, Bernhard A Herzog, Melvin Clouse, David A Halon, Jonathan Leipsic, David Bush, Reda Jakamy, Kai Sun, Lin Yang, Thorsten Johnson, Jean-Pierre Laissy, Roy Marcus, Simone Muraglia, Jean-Claude Tardif, Benjamin Chow, Narinder Paul, David Maintz, John Hoe, Albert de Roos, Robert Haase, Michael Laule, Peter Schlattmann, Marc Dewey,

The original version of this article, published on 19 March 2018, unfortunately contained a mistake. The following correction has therefore been made in the original: The names of the authors Philipp A. Kaufmann, Ronny Ralf Buechel and Bernhard A. Herzog were presented incorrectly. ... Read more >>

Eur Radiol (European radiology)
[2018, 28(11):4919-4921]

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Reduction in radiation exposure in cardiovascular computed tomography imaging: results from the PROspective multicenter registry on radiaTion dose Estimates of cardiac CT angIOgraphy iN daily practice in 2017 (PROTECTION VI).

Thomas J Stocker, Simon Deseive, Jonathon Leipsic, Martin Hadamitzky, Marcus Y Chen, Ronen Rubinshtein, Mathias Heckner, Jeroen J Bax, Xiang-Ming Fang, Erik Lerkevang Grove, John Lesser, Pál Maurovich-Horvat, James Otton, Sanghoon Shin, Gianluca Pontone, Hugo Marques, Benjamin Chow, Cesar H Nomura, Ramzi Tabbalat, Axel Schmermund, Joon-Won Kang, Christopher Naoum, Melany Atkins, Eugenio Martuscelli, Steffen Massberg, Jörg Hausleiter, ,

<h4>Aims</h4>Advances of cardiac computed tomography angiography (CTA) have been developed for dose reduction, but their efficacy in clinical practice is largely unknown. This study was designed to evaluate radiation dose exposure and utilization of dose-saving strategies for contrast-enhanced cardiac CTA in daily practice.<h4>Methods and results</h4>Sixty one hospitals from 32 countries ... Read more >>

Eur Heart J (European heart journal)
[2018, 39(41):3715-3723]

Cited: 20 times

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Applicability and accuracy of pretest probability calculations implemented in the NICE clinical guideline for decision making about imaging in patients with chest pain of recent onset.

Robert Roehle, Viktoria Wieske, Georg M Schuetz, Pascal Gueret, Daniele Andreini, Willem Bob Meijboom, Gianluca Pontone, Mario Garcia, Hatem Alkadhi, Lily Honoris, Jörg Hausleiter, Nuno Bettencourt, Elke Zimmermann, Sebastian Leschka, Bernhard Gerber, Carlos Rochitte, U Joseph Schoepf, Abbas Arjmand Shabestari, Bjarne Nørgaard, Akira Sato, Juhani Knuuti, Matthijs F L Meijs, Harald Brodoefel, Shona M M Jenkins, Kristian Altern Øvrehus, Axel Cosmus Pyndt Diederichsen, Ashraf Hamdan, Bjørn Arild Halvorsen, Vladimir Mendoza Rodriguez, Yung Liang Wan, Johannes Rixe, Mehraj Sheikh, Christoph Langer, Said Ghostine, Eugenio Martuscelli, Hiroyuki Niinuma, Arthur Scholte, Konstantin Nikolaou, Geir Ulimoen, Zhaoqi Zhang, Hans Mickley, Koen Nieman, Philipp A Kaufmann, Ronny Ralf Buechel, Bernhard A Herzog, Melvin Clouse, David A Halon, Jonathan Leipsic, David Bush, Reda Jakamy, Kai Sun, Lin Yang, Thorsten Johnson, Jean-Pierre Laissy, Roy Marcus, Simone Muraglia, Jean-Claude Tardif, Benjamin Chow, Narinder Paul, David Maintz, John Hoe, Albert de Roos, Robert Haase, Michael Laule, Peter Schlattmann, Marc Dewey,

<h4>Objectives</h4>To analyse the implementation, applicability and accuracy of the pretest probability calculation provided by NICE clinical guideline 95 for decision making about imaging in patients with chest pain of recent onset.<h4>Methods</h4>The definitions for pretest probability calculation in the original Duke clinical score and the NICE guideline were compared. We also ... Read more >>

Eur Radiol (European radiology)
[2018, 28(9):4006-4017]

Cited: 1 time

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Clinical recommendations on Cardiac-CT in 2015: a position paper of the Working Group on Cardiac-CT and Nuclear Cardiology of the Italian Society of Cardiology.

Daniele Andreini, Eugenio Martuscelli, Andrea Igoren Guaricci, Nazario Carrabba, Marco Magnoni, Carlo Tedeschi, Antonio Pelliccia, Gianluca Pontone, ,

We worked out a position paper on cardiac-computed tomography (CCT) endorsed by the Working Group on CCT and Nuclear Cardiology of the Italian Society of Cardiology. The CCT clinical indications were discussed and formulated according to the following two modalities: a brief paragraph dedicated to each indication, with the description ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2016, 17(2):73-84]

Cited: 9 times

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Effects of chronic treatment with the new ultra-long-acting β2 -adrenoceptor agonist indacaterol alone or in combination with the β1 -adrenoceptor blocker metoprolol on cardiac remodelling.

Barbara Rinaldi, Maria Donniacuo, Loredana Sodano, Giulia Gritti, Eugenio Martuscelli, Augusto Orlandi, Concetta Rafaniello, Francesco Rossi, Luigino Calzetta, Annalisa Capuano, Maria Gabriella Matera,

<h4>Background and purpose</h4>The ability of a chronic treatment with indacaterol, a new ultra-long-acting β2 -adrenoceptor agonist, to reverse cardiac remodelling and its effects in combination with metoprolol, a selective β1 -adrenoceptor antagonist, were investigated on myocardial infarction in a rat model of heart failure (HF).<h4>Experimental approach</h4>We investigated the effects of ... Read more >>

Br J Pharmacol (British journal of pharmacology)
[2015, 172(14):3627-3637]

Cited: 10 times

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Prospective Randomized Trial on Radiation Dose Estimates of CT Angiography Applying Iterative Image Reconstruction: The PROTECTION V Study.

Simon Deseive, Marcus Y Chen, Grigorios Korosoglou, Jonathon Leipsic, Eugenio Martuscelli, Patricia Carrascosa, Saeed Mirsadraee, Charles White, Martin Hadamitzky, Stefan Martinoff, Anna-Leonie Menges, Bernhard Bischoff, Steffen Massberg, Jörg Hausleiter,

<h4>Objectives</h4>The purpose of this study was to assess the potential of iterative image reconstruction (IR) of images for radiation dose reduction in coronary computed tomography angiography (CTA). Therefore, IR in combination with 30% tube current reduction was compared with standard scanning with filtered back projection (FBP) reconstruction.<h4>Background</h4>Lately, new IR techniques with ... Read more >>

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2015, 8(8):888-896]

Cited: 22 times

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Image quality and radiation exposure with prospectively ECG-triggered axial scanning for coronary CT angiography: the multicenter, multivendor, randomized PROTECTION-III study.

Jörg Hausleiter, Tanja S Meyer, Eugenio Martuscelli, Pietro Spagnolo, Hiroaki Yamamoto, Patricia Carrascosa, Thomas Anger, Lukas Lehmkuhl, Hatem Alkadhi, Stefan Martinoff, Martin Hadamitzky, Franziska Hein, Bernhard Bischoff, Miriam Kuse, Albert Schömig, Stephan Achenbach,

<h4>Objectives</h4>The purpose of this study was to evaluate image quality and radiation dose using a prospectively electrocardiogram (ECG)-triggered axial scan protocol compared with standard retrospective ECG-gated helical scanning for coronary computed tomography angiography.<h4>Background</h4>Concerns have been raised regarding radiation exposure during coronary computed tomography angiography. Although the use of prospectively ECG-triggered ... Read more >>

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2012, 5(5):484-493]

Cited: 92 times

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Individual patient data meta-analysis for the clinical assessment of coronary computed tomography angiography: protocol of the Collaborative Meta-Analysis of Cardiac CT (CoMe-CCT).

Georg M Schuetz, Peter Schlattmann, Stephan Achenbach, Matthew Budoff, Mario J Garcia, Robert Roehle, Gianluca Pontone, Willem Bob Meijboom, Daniele Andreini, Hatem Alkadhi, Lily Honoris, Nuno Bettencourt, Jörg Hausleiter, Sebastian Leschka, Bernhard L Gerber, Matthijs Fl Meijs, Abbas Arjmand Shabestari, Akira Sato, Elke Zimmermann, Uwe J Schoepf, Axel Diederichsen, David A Halon, Vladimir Mendoza-Rodriguez, Ashraf Hamdan, Bjarne L Nørgaard, Harald Brodoefel, Kristian A Ovrehus, Shona Mm Jenkins, Bjørn A Halvorsen, Johannes Rixe, Mehraj Sheikh, Christoph Langer, Eugenio Martuscelli, Andrea Romagnoli, Arthur Jha Scholte, Roy P Marcus, Geir R Ulimoen, Koen Nieman, Hans Mickley, Konstantin Nikolaou, Jean-Claude Tardif, Thorsten Rc Johnson, Simone Muraglia, Benjamin Jw Chow, David Maintz, Michael Laule, Marc Dewey,

<h4>Unlabelled</h4><h4>Background</h4>Coronary computed tomography angiography has become the foremost noninvasive imaging modality of the coronary arteries and is used as an alternative to the reference standard, conventional coronary angiography, for direct visualization and detection of coronary artery stenoses in patients with suspected coronary artery disease. Nevertheless, there is considerable debate regarding ... Read more >>

Syst Rev (Systematic reviews)
[2013, 2:13]

Cited: 10 times

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Partners in crime in the setting of recurring cardiac arrest.

Lida P Papavasileiou, Giovanni B Forleo, Luca Santini, Eugenio Martuscelli, Francesco Romeo,

No previous reports are available about the potential dramatic effects resulting from the combination of acquired long QT interval not associated to bradycardia and myocardial ischemia. We report the case of a man that during acute necrotic pancreatitis presented QT interval prolongation without bradycardia, TdP, and two episodes of cardiac ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2011, 2011:198653]

Cited: 1 time

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Image quality and radiation exposure with a low tube voltage protocol for coronary CT angiography results of the PROTECTION II Trial.

Jörg Hausleiter, Stefan Martinoff, Martin Hadamitzky, Eugenio Martuscelli, Iris Pschierer, Gudrun M Feuchtner, Paz Catalán-Sanz, Benedikt Czermak, Tanja S Meyer, Franziska Hein, Bernhard Bischoff, Miriam Kuse, Albert Schömig, Stephan Achenbach,

<h4>Objectives</h4>The purpose of this study was to evaluate image quality and radiation dose using a 100 kVp tube voltage scan protocol compared with standard 120 kVp for coronary computed tomography angiography (CTA).<h4>Background</h4>Concerns have been raised about radiation exposure during coronary CTA. The use of a 100 kVp tube voltage scan ... Read more >>

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2010, 3(11):1113-1123]

Cited: 120 times

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Coronary-to-bronchial artery fistula in a patient with multivessel coronary disease treated by percutaneous coronary intervention.

Stefano Rigattieri, Silvio Fedele, Massimiliano Sperandio, Eugenio Martuscelli, Giovanni Simonetti, Giuliano Altamura, Paolo Loschiavo,

We describe the case of a 78-year-old patient, admitted to our hospital with an acute coronary syndrome. Coronary angiography showed multivessel coronary artery disease and an anomalous coronary vessel branching from the right coronary artery. After successful percutaneous revascularization and discharge, the anomalous vessel was diagnosed by contrast enhanced 64-multidetector ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2010, 11(8):625-627]

Cited: 6 times

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Evaluation of coronary in-stent restenosis by 64-slice computed tomography in patients with optimal heart rate control by systematic administration of beta-blocker drugs.

Eugenio Martuscelli, Andrea Romagnoli, Alessia D'eliseo, Massimiliano Sperandio, Marco Di Luozzo, Barbara De Angelis, Francesco Romeo, Giovanni Simonetti,

<h4>Background</h4>Imaging artifacts due to metallic stent struts can reduce the diagnostic accuracy of multislice computed tomography (MSCT) in the evaluation of in-stent restenosis (ISR). Our aim was to determine the accuracy of binary ISR exclusion using a 64-slice MSCT scanner and a systematic administration of beta-blockers having an aggressive heart ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2010, 11(6):431-439]

Cited: 4 times

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Pharmacological modulation of beta-adrenoceptor function in patients with coexisting chronic obstructive pulmonary disease and chronic heart failure.

Maria Gabriella Matera, Eugenio Martuscelli, Mario Cazzola,

Pharmacological modulation of beta-adrenoceptor function is one of the critical issues in the treatment of patients with concurrent chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF). A volume of published evidence sustains the role of long-acting beta(2)-agonists in the treatment of stable COPD, but beta-agonists seem to be ... Read more >>

Pulm Pharmacol Ther (Pulmonary pharmacology & therapeutics)
[2010, 23(1):1-8]

Cited: 23 times

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Single coronary artery with anomalous origin of right coronary artery from left main stem.

Enrica Mariano, Eugenio Martuscelli, Riccardo Morgagni, Francesco Romeo,

We report the case of a 57-year-old man with unstable angina that was taken up for coronary angiography, which showed an anomalous right coronary artery originating from left main stem. ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2009, 10(9):733-735]

Cited: 2 times

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Regression and shift in composition of coronary atherosclerotic plaques by pioglitazone: insight from an intravascular ultrasound analysis.

Fabrizio Clementi, Marco Di Luozzo, Ruggiero Mango, Giulio Luciani, Antonio Trivisonno, Francesco Pizzuto, Eugenio Martuscelli, Jawahar L Mehta, Francesco Romeo,

<h4>Background</h4>Plaque reduction with the use of pioglitazone and statin combination therapy has been observed in carotid plaque. We sought to investigate the effect of combination therapy with statins and pioglitazone on coronary plaque regression and composition with the use of intravascular ultrasound (IVUS) and intravascular ultrasound-virtual histology (IVUS-VH).<h4>Methods</h4>We analysed 29 ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2009, 10(3):231-237]

Cited: 11 times

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Single coronary artery type R III-C imaged by 64 slice spiral computed tomography.

Eugenio Martuscelli, Emanuele Casciani, Alessia D'eliseo, Francesco Romeo, Gianfranco Gualdi,

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2008, 9(10):1078-1079]

Cited: 1 time

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[Computed tomography angiography: how to choose between fear of change and fanatic excess?].

Eugenio Martuscelli,

G Ital Cardiol (Rome) (Giornale italiano di cardiologia (2006))
[2007, 8(8):485-490]

Cited: 0 times

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In-stent restenosis and multislice computed tomography: is the method ready to start?

Eugenio Martuscelli, Cinzia Razzini, Alessia D'Eliseo, Marco Di Luozzo, Borzi Mauro, Francesco Romeo,

We present two patients revascularized by coronary stents and evaluated by multislice computed tomography (CT). In first patient, angio-CT (16 slices/rotation scanner) detected a high-grade restenosis on the distal part of a drug-eluting stent; conventional coronary angiography confirmed the diagnosis. In second patient, angio-CT (64 slices/rotation) showed a tissue proliferation, ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2007, 8(5):377-380]

Cited: 1 time

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Revascularization strategy in patients with multivessel disease and a major vessel chronically occluded; data from the CABRI trial.

Eugenio Martuscelli, Fabrizio Clementi, Mark M Gallagher, Alessia D'Eliseo, Gaetano Chiricolo, Antonio Nigri, Benedetto Marino, Francesco Romeo, ,

<h4>Objective</h4>In patients with multivessel coronary artery disease and total occlusion of major epicardial vessel, completeness of revascularization has not been investigated in specific trials comparing the surgical and the percutaneous revascularization strategy. Analyzing the database of the CABRI study, which randomized a substantial number of these patients, we investigated the ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2008, 33(1):4-8]

Cited: 8 times

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Multislice computed tomography in an asymptomatic high-risk population.

Francesco Romeo, Roberto Leo, Fabrizio Clementi, Cinzia Razzini, Mauro Borzi, Eugenio Martuscelli, Francesco Pizzuto, Gaetano Chiricolo, Jawahar L Mehta,

Approximately 50% of all acute coronary syndromes occur in previously asymptomatic patients. This study evaluated the value of multislice computed tomography for early detection of significant coronary artery disease (CAD) in high-risk asymptomatic subjects. One hundred sixty-eight asymptomatic subjects with >or=1 major risk factor (hypertension, diabetes, hypercholesterolemia, family history, or ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2007, 99(3):325-328]

Cited: 33 times

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