Full Text Journal Articles by
Author Erwin J O Kompanje

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Advanced consent for acute stroke trials - Authors' reply.

Jeroen T J M van Dijck, Erwin J O Kompanje, Paul J Nederkoorn, Wilco C Peul, Diederik W J Dippel,

Lancet Neurol (The Lancet. Neurology)
[2021, 20(3):170-171]

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Sharing ICU Patient Data Responsibly Under the Society of Critical Care Medicine/European Society of Intensive Care Medicine Joint Data Science Collaboration: The Amsterdam University Medical Centers Database (AmsterdamUMCdb) Example.

Patrick J Thoral, Jan M Peppink, Ronald H Driessen, Eric J G Sijbrands, Erwin J O Kompanje, Lewis Kaplan, Heatherlee Bailey, Jozef Kesecioglu, Maurizio Cecconi, Matthew Churpek, Gilles Clermont, Mihaela van der Schaar, Ari Ercole, Armand R J Girbes, Paul W G Elbers, ,

<h4>Objectives</h4>Critical care medicine is a natural environment for machine learning approaches to improve outcomes for critically ill patients as admissions to ICUs generate vast amounts of data. However, technical, legal, ethical, and privacy concerns have so far limited the critical care medicine community from making these data readily available. The ... Read more >>

Crit Care Med (Critical care medicine)
[2021, :]

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Informed consent procedures for emergency interventional research in patients with traumatic brain injury and ischaemic stroke.

Erwin J O Kompanje, Jeroen T J M van Dijck, Vicky Chalos, Sophie A van den Berg, Paula M Janssen, Paul J Nederkoorn, Mathieu van der Jagt, Giuseppe Citerio, Nino Stocchetti, Diederik W J Dippel, Wilco C Peul,

Health-care professionals and researchers have a legal and ethical responsibility to inform patients before carrying out diagnostic tests or treatment interventions as part of a clinical study. Interventional research in emergency situations can involve patients with some degree of acute cognitive impairment, as is regularly the case in traumatic brain ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2020, 19(12):1033-1042]

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Treatment Limitation Decisions in Critically Ill Patients With a Malignancy on the Intensive Care Unit.

Esther N van der Zee, Jelle L Epker, Jan Bakker, Dominique D Benoit, Erwin J O Kompanje,

<b>Background: </b>Treatment limitation decisions (TLDs) on the ICU can be challenging, especially in patients with a malignancy. Up-to-date literature regarding TLDs in critically ill patients with a malignancy admitted to the ICU is scarce. The aim was to compare the incidence of written TLDs between patients with an active malignancy, ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2021, 36(1):42-50]

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Informed consent procedures in patients with an acute inability to provide informed consent: Policy and practice in the CENTER-TBI study.

Roel P J van Wijk, Jeroen T J M van Dijck, Marjolein Timmers, Ernest van Veen, Giuseppe Citerio, Hester F Lingsma, Andrew I R Maas, David K Menon, Wilco C Peul, Nino Stocchetti, Erwin J O Kompanje, ,

<h4>Purpose</h4>Enrolling traumatic brain injury (TBI) patients with an inability to provide informed consent in research is challenging. Alternatives to patient consent are not sufficiently embedded in European and national legislation, which allows procedural variation and bias. We aimed to quantify variations in informed consent policy and practice.<h4>Methods</h4>Variation was explored in ... Read more >>

J Crit Care (Journal of critical care)
[2020, 59:6-15]

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End-of-life practices in traumatic brain injury patients: Report of a questionnaire from the CENTER-TBI study.

Ernest van Veen, Mathieu van der Jagt, Giuseppe Citerio, Nino Stocchetti, Jelle L Epker, Diederik Gommers, Lex Burdorf, David K Menon, Andrew I R Maas, Hester F Lingsma, Erwin J O Kompanje, ,

<h4>Purpose</h4>We aimed to study variation regarding specific end-of-life (EoL) practices in the intensive care unit (ICU) in traumatic brain injury (TBI) patients.<h4>Materials and methods</h4>Respondents from 67 hospitals participating in The Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study completed several questionnaires on management of TBI patients.<h4>Results</h4>In 60% ... Read more >>

J Crit Care (Journal of critical care)
[2020, 58:78-88]

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How do 66 European institutional review boards approve one protocol for an international prospective observational study on traumatic brain injury? Experiences from the CENTER-TBI study.

Marjolein Timmers, Jeroen T J M van Dijck, Roel P J van Wijk, Valerie Legrand, Ernest van Veen, Andrew I R Maas, David K Menon, Giuseppe Citerio, Nino Stocchetti, Erwin J O Kompanje, ,

BACKGROUND:The European Union (EU) aims to optimize patient protection and efficiency of health-care research by harmonizing procedures across Member States. Nonetheless, further improvements are required to increase multicenter research efficiency. We investigated IRB procedures in a large prospective European multicenter study on traumatic brain injury (TBI), aiming to inform and ... Read more >>

BMC Med Ethics (BMC medical ethics)
[2020, 21(1):36]

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Prevention Is Better Than Treatment, A Different Perspective on Distress Management After Comfort Care Extubation.

Jelle L Epker, Erwin J O Kompanje,

J Pain Symptom Manage (Journal of pain and symptom management)
[2020, 59(1):e1]

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The patient with severe traumatic brain injury: clinical decision-making: the first 60 min and beyond.

Jeroen T J M van Dijck, Ronald H M A Bartels, Jan C M Lavrijsen, Gerard M Ribbers, Erwin J O Kompanje, Wilco C Peul, ,

PURPOSE OF REVIEW:There is an urgent need to discuss the uncertainties and paradoxes in clinical decision-making after severe traumatic brain injury (s-TBI). This could improve transparency, reduce variability of practice and enhance shared decision-making with proxies. RECENT FINDINGS:Clinical decision-making on initiation, continuation and discontinuation of medical treatment may encompass substantial ... Read more >>

Curr Opin Crit Care (Current opinion in critical care)
[2019, 25(6):622-629]

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Neurological Deficits in Stroke Patients that May Impede the Capacity to Provide Informed Consent for Endovascular Treatment Trials.

Paula M Janssen, Vicky Chalos, Sophie A van den Berg, Erwin J O Kompanje, Paul J Nederkoorn, Bart H van der Worp, Wim H van Zwam, Diederik W J Dippel, ,

BACKGROUND:We assessed the occurrence of neurological deficits that may impede the capacity to provide consent for trial participation in patients with an acute stroke, who are eligible for endovascular treatment (EVT). METHODS:We used data from the Multicenter Randomized Controlled Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2019, 28(12):104447]

Cited: 1 time

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Ethical climate and intention to leave among critical care clinicians: an observational study in 68 intensive care units across Europe and the United States.

Bo Van den Bulcke, Victoria Metaxa, Anna K Reyners, Katerina Rusinova, Hanne I Jensen, J Malmgren, Michael Darmon, Daniel Talmor, Anne-Pascale Meert, Laura Cancelliere, László Zubek, Paulo Maia, Andrej Michalsen, Erwin J O Kompanje, Peter Vlerick, Jolien Roels, Stijn Vansteelandt, Johan Decruyenaere, Elie Azoulay, Stijn Vanheule, Ruth Piers, Dominique Benoit, ,

<h4>Purpose</h4>Apart from organizational issues, quality of inter-professional collaboration during ethical decision-making may affect the intention to leave one's job. To determine whether ethical climate is associated with the intention to leave after adjustment for country, ICU and clinicians characteristics.<h4>Methods</h4>Perceptions of the ethical climate among clinicians working in 68 adult ICUs ... Read more >>

Intensive Care Med (Intensive care medicine)
[2020, 46(1):46-56]

Cited: 3 times

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[Is medical scientific research allowed in emergency situations without prior consent from the patient?]

Marjolein Timmers, Ditty van Duijn, Erwin J O Kompanje,

Is medical scientific research allowed in emergency situations without prior consent from the patient? Obtaining consent for conducting scientific research before carrying out an experimental medical treatment is not always possible in emergency situations. We discuss features that can be used to determine whether research can be conducted using the ... Read more >>

Ned Tijdschr Geneeskd (Nederlands tijdschrift voor geneeskunde)
[2019, 163:]

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[To act or not to act? Developments in prenatal and postnatal care for children with spina bifida aperta].

Bart T H Lutters, Jochem K H Spoor, T H Rob de Jong, Erwin J O Kompanje, A A Eduard Verhagen, Oebo F Brouwer, Rob J M Groen,

To act or not to act? Developments in prenatal and postnatal care for children with spina bifida aperta Until the middle of the twentieth century, newborns with spina bifida aperta had low chances of survival. Advances in the treatment of hydrocephalus, among other conditions, led to increased chances of survival ... Read more >>

Ned Tijdschr Geneeskd (Nederlands tijdschrift voor geneeskunde)
[2019, 163:]

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Osteochondromatosis (multiple cartilaginous exostoses) in an immature killer whale Orcinus orca.

Maíra Laeta, Erwin J O Kompanje, Alastair Watson, Sheila M F M Souza, Katharina Dittmar, Sandra C Cuenca, Lucas B Hassel, Salvatore Siciliano,

An immature killer whale Orcinus orca found dead on the southeastern Brazilian coast had multiple bone proliferations: on the skull, vertebrae, hemal arches, and ribs. The bony formations were characterized as multiple osteochondromas, as defined by osteochondromatosis. The diagnosis was based on macroscopic and radiographic observations. These benign osseocartilaginous tumors ... Read more >>

Dis Aquat Organ (Diseases of aquatic organisms)
[2019, 134(3):209-213]

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Parting is such sweet sorrow.

Erwin J O Kompanje,

Intensive Care Med (Intensive care medicine)
[2019, 45(7):1035-1036]

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Will the Eu Data Protection Regulation 2016/679 Inhibit Critical Care Research?

Marjolein Timmers, Evert-Ben Van Veen, Andrew I R Maas, Erwin J O Kompanje,

There is an inherent tension between critical care research and data protection. Because of their condition it is not possible to ask for the patients' informed consent to be enrolled in observational research at the point of admission to the hospital. Often this is not possible at a later moment ... Read more >>

Med Law Rev (Medical law review)
[2019, 27(1):59-78]

Cited: 4 times

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Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study.

Ernest van Veen, Mathieu van der Jagt, Maryse C Cnossen, Andrew I R Maas, Inez D de Beaufort, David K Menon, Giuseppe Citerio, Nino Stocchetti, Wim J R Rietdijk, Jeroen T J M van Dijck, Erwin J O Kompanje, ,

<h4>Background</h4>We aimed to investigate the extent of the agreement on practices around brain death and postmortem organ donation.<h4>Methods</h4>Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study centers completed several questionnaires (response rate: 99%).<h4>Results</h4>Regarding practices around brain death, we found agreement on the clinical evaluation (prerequisites ... Read more >>

Crit Care (Critical care (London, England))
[2018, 22(1):306]

Cited: 3 times

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Time-limited trial of intensive care treatment: an overview of current literature.

Eva E Vink, Elie Azoulay, Arthur Caplan, Erwin J O Kompanje, Jan Bakker,

In critically ill patients, it is frequently challenging to identify who will benefit from admission to the intensive care unit and life-sustaining interventions when the chances of a meaningful outcome are unclear. In addition, the acute illness not only affects the patients but also family members or surrogates who often ... Read more >>

Intensive Care Med (Intensive care medicine)
[2018, 44(9):1369-1377]

Cited: 11 times

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Controlled Donation After Circulatory Determination of Death: Ethical Issues in Withdrawing Life-Sustaining Therapy.

Erwin J O Kompanje, Jelle L Epker,

J Intensive Care Med (Journal of intensive care medicine)
[2018, 33(4):270-271]

Cited: 0 times

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Ethical decision-making climate in the ICU: theoretical framework and validation of a self-assessment tool.

Bo Van den Bulcke, Ruth Piers, Hanne Irene Jensen, Johan Malmgren, Victoria Metaxa, Anna K Reyners, Michael Darmon, Katerina Rusinova, Daniel Talmor, Anne-Pascale Meert, Laura Cancelliere, Làszló Zubek, Paolo Maia, Andrej Michalsen, Johan Decruyenaere, Erwin J O Kompanje, Elie Azoulay, Reitske Meganck, Ariëlla Van de Sompel, Stijn Vansteelandt, Peter Vlerick, Stijn Vanheule, Dominique D Benoit,

BACKGROUND:Literature depicts differences in ethical decision-making (EDM) between countries and intensive care units (ICU). OBJECTIVES:To better conceptualise EDM climate in the ICU and to validate a tool to assess EDM climates. METHODS:Using a modified Delphi method, we built a theoretical framework and a self-assessment instrument consisting of 35 statements. This ... Read more >>

BMJ Qual Saf (BMJ quality & safety)
[2018, 27(10):781-789]

Cited: 10 times

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Burnout, boreout and compassion fatigue on the ICU: it is not about work stress, but about lack of existential significance and professional performance.

Erwin J O Kompanje,

Intensive Care Med (Intensive care medicine)
[2018, 44(5):690-691]

Cited: 2 times

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Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research.

Andrew I R Maas, David K Menon, P David Adelson, Nada Andelic, Michael J Bell, Antonio Belli, Peter Bragge, Alexandra Brazinova, András Büki, Randall M Chesnut, Giuseppe Citerio, Mark Coburn, D Jamie Cooper, A Tamara Crowder, Endre Czeiter, Marek Czosnyka, Ramon Diaz-Arrastia, Jens P Dreier, Ann-Christine Duhaime, Ari Ercole, Thomas A van Essen, Valery L Feigin, Guoyi Gao, Joseph Giacino, Laura E Gonzalez-Lara, Russell L Gruen, Deepak Gupta, Jed A Hartings, Sean Hill, Ji-Yao Jiang, Naomi Ketharanathan, Erwin J O Kompanje, Linda Lanyon, Steven Laureys, Fiona Lecky, Harvey Levin, Hester F Lingsma, Marc Maegele, Marek Majdan, Geoffrey Manley, Jill Marsteller, Luciana Mascia, Charles McFadyen, Stefania Mondello, Virginia Newcombe, Aarno Palotie, Paul M Parizel, Wilco Peul, James Piercy, Suzanne Polinder, Louis Puybasset, Todd E Rasmussen, Rolf Rossaint, Peter Smielewski, Jeannette Söderberg, Simon J Stanworth, Murray B Stein, Nicole von Steinbüchel, William Stewart, Ewout W Steyerberg, Nino Stocchetti, Anneliese Synnot, Braden Te Ao, Olli Tenovuo, Alice Theadom, Dick Tibboel, Walter Videtta, Kevin K W Wang, W Huw Williams, Lindsay Wilson, Kristine Yaffe, ,

Lancet Neurol (The Lancet. Neurology)
[2017, 16(12):987-1048]

Cited: 214 times

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Counterbalancing work-related stress? Work engagement among intensive care professionals.

Margo M C van Mol, Marjan D Nijkamp, Jan Bakker, Wilmar B Schaufeli, Erwin J O Kompanje,

BACKGROUND AND OBJECTIVES:Working in an Intensive Care Unit (ICU) is increasingly complex and is also physically, cognitively and emotionally demanding. Although the negative emotions of work-related stress have been well studied, the opposite perspective of work engagement might also provide valuable insight into how these emotional demands may be countered. ... Read more >>

Aust Crit Care (Australian critical care : official journal of the Confederation of Australian Critical Care Nurses)
[2018, 31(4):234-241]

Cited: 2 times

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Will we become more compassionate or empathic intensive care professionals by watching films and documentaries about suffering?

Erwin J O Kompanje, Margo M van Mol, Joachim Weigel,

Intensive Care Med (Intensive care medicine)
[2017, 43(4):560-561]

Cited: 0 times

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In Reply: The History of the Kernohan Notch Revisited.

Ruben Dammers, Victor Volovici, Erwin J O Kompanje,

Neurosurgery (Neurosurgery)
[2016, 79(4):E546-7]

Cited: 0 times

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