Full Text Journal Articles by
Author Erwin Blessing

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Retrograde use of the Outback™ re-entry catheter in complex infrainguinal arterial recanalizations.

Lorenzo Patrone, Grigorios Korosoglou, Braham Dharmarajah, Selva Theivacumar, Muliadi Antaredja, Ralph Oberacker, Lisa Tilemann, Erwin Blessing,

<h4>Purpose</h4>Retrograde recanalizations gained increasing recognition in complex arterial occlusive disease. Re-entry devices are a well described adjunct for antegrade recanalizations. We present our experience with retrograde, infrainguinal recanalizations using the Outback™ re-entry catheter in challenging chronic total occlusions.<h4>Materials and methods</h4>We report data from a retrospective multicenter registry in complex retrograde ... Read more >>

J Vasc Surg (Journal of vascular surgery)
[2021, :]

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Distal retrieval of dislodged and migrated guidewires after retrograde puncture of the deep femoral and dorsal pedal artery. A case series.

Grigorios Korosoglou, Sorin Giusca, Muliadi Antaredja, Andrej Schmidt, Erwin Blessing,

We report on retrograde retrieval of the soft end of dislodged guidewires during complex interventions. Interventionalists may consider this as an option for the endovascular management of this complication if an antegrade retrieval is not possible or fails. ... Read more >>

Clin Case Rep (Clinical case reports)
[2021, 9(4):2077-2082]

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Predictors and Prognostic Implications of Cardiac Arrhythmias in Patients Hospitalized for COVID-19.

Maura M Zylla, Uta Merle, Johannes A Vey, Grigorios Korosoglou, Eva Hofmann, Michael Müller, Felix Herth, Werner Schmidt, Erwin Blessing, Christoph Göggelmann, Norbert Weidner, Mascha O Fiedler, Markus A Weigand, Florian Kälble, Christian Morath, Johannes Leiner, Meinhard Kieser, Hugo A Katus, Dierk Thomas,

<h4>Background</h4>Cardiac manifestation of COVID-19 has been reported during the COVID pandemic. The role of cardiac arrhythmias in COVID-19 is insufficiently understood. This study assesses the incidence of cardiac arrhythmias and their prognostic implications in hospitalized COVID-19-patients.<h4>Methods</h4>A total of 166 patients from eight centers who were hospitalized for COVID-19 from 03/2020-06/2020 ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(1):]

Cited: 4 times

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Implantation of vascular mimetic implants in challenging chronic total occlusions - SuperaTM Extreme.

Erwin Blessing, Muliadi Antaredja, Lisa Tilemann, Ralph Oberacker,

Standard nitinol stents (SNS), with or without drug eluting technology, are an essential tool within the interventional armamentarium in the treatment of patients with peripheral arterial disease. However, they are plagued by a number of limitations: a.) stent fractures, although observed predominately in first-generation stents, do still occur in state-of-the ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2020, :1-5]

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COMPARE: prospective, randomized, non-inferiority trial of high- vs. low-dose paclitaxel drug-coated balloons for femoropopliteal interventions.

Sabine Steiner, Andrej Schmidt, Thomas Zeller, Gunnar Tepe, Marcus Thieme, Lars Maiwald, Henrik Schröder, Wulf Euringer, Matthias Ulrich, Klaus Brechtel, Steffen Brucks, Erwin Blessing, Johannes Schuster, Ralf Langhoff, Sebastian Schellong, Norbert Weiss, Dierk Scheinert,

<h4>Aims</h4>Drug-coated balloons (DCBs) for femoropopliteal interventions have not been tested against each other. We aimed to directly compare efficacy and safety of a high-dose (In.Pact™) vs. low-dose (Ranger™) DCB with nominal paclitaxel densities of 3.5 vs. 2.0 μg/mm2.<h4>Methods and results</h4>Within a prospective, multicentre, non-inferiority, clinical trial 414 patients with symptomatic femoropopliteal ... Read more >>

Eur Heart J (European heart journal)
[2020, 41(27):2541-2552]

Cited: 1 time

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Cancer associated thrombosis in everyday practice: perspectives from GARFIELD-VTE.

Jeffrey I Weitz, Sylvia Haas, Walter Ageno, Samuel Z Goldhaber, Alexander G G Turpie, Shinya Goto, Pantep Angchaisuksiri, Jørn Dalsgaard Nielsen, Gloria Kayani, Alfredo E Farjat, Sebastian Schellong, Henri Bounameaux, Lorenzo G Mantovani, Paolo Prandoni, Ajay K Kakkar, ,

Venous thromboembolism (VTE) is common in cancer patients and is an important cause of morbidity and mortality. The Global Anticoagulant Registry in the FIELD (GARFIELD)-VTE (ClinicalTrials.gov: NCT02155491) is a prospective, observational study of 10,684 patients with objectively diagnosed VTE from 415 sites in 28 countries. We compared baseline characteristics, VTE ... Read more >>

J Thromb Thrombolysis (Journal of thrombosis and thrombolysis)
[2020, 50(2):267-277]

Cited: 1 time

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Optimized drug-coated balloon angioplasty of the superficial femoral and proximal popliteal arteries using the Tack Endovascular System: TOBA III 12-month results.

Marianne Brodmann, Christian Wissgott, Klaus Brechtel, Sigrid Nikol, Thomas Zeller, Michael Lichtenberg, Erwin Blessing, William Gray, ,

<h4>Objective</h4>The Tack Endovascular System (Intact Vascular, Wayne, Pa) combines low-metallic content with focal delivery to seal areas of dissection associated with balloon angioplasty. The device system is designed to treat vascular dissections in the superficial femoral and proximal popliteal arteries. Tack implants exert low radial force and are associated with ... Read more >>

J Vasc Surg (Journal of vascular surgery)
[2020, 72(5):1636-1647.e1]

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Efficacy and safety of a novel paclitaxel-nano-coated balloon for femoropopliteal angioplasty: one-year results of the EffPac trial.

Ulf Teichgräber, Thomas Lehmann, René Aschenbach, Dierk Scheinert, Thomas Zeller, Klaus Brechtel, Erwin Blessing, Michael Lichtenberg, Sebastian Sixt, Steffen Brucks, Ulrich Beschorner, Christof Tobias Klumb, Markus Thieme, ,

AIMS:Although paclitaxel drug-coated balloon (DCB) angioplasty is an established endovascular treatment for peripheral artery disease, restenosis remains a major concern. Thus, we compared a novel paclitaxel-coated DCB with nano-coating technology with uncoated plain old balloon angioplasty (POBA). METHODS AND RESULTS:This multicentre trial randomly assigned 171 patients with stenotic and occlusive ... Read more >>

EuroIntervention (EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology)
[2020, 15(18):e1633-e1640]

Cited: 3 times

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Long-term outcome upon treatment of calcified lesions of the lower limb using scoring angioplasty balloon (AngioSculpt™).

Mariya Kronlage, Carolin Werner, Matthias Dufner, Erwin Blessing, Oliver J Müller, Britta Heilmeier, Hugo A Katus, Christian Erbel,

<h4>Aims</h4>In peripheral artery disease (PAD), endovascular treatment success of heavily calcified lesions is often compromised by a number of vascular complications, such as recoils, dissections and need for target vessel re-interventions. The increasing use of scoring balloon techniques has raised the hope for better periprocedural outcomes; however, the knowledge regarding ... Read more >>

Clin Res Cardiol (Clinical research in cardiology : official journal of the German Cardiac Society)
[2020, 109(9):1177-1185]

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Drug-coated Balloon Angioplasty of Femoropopliteal Lesions Maintained Superior Efficacy over Conventional Balloon: 2-year Results of the Randomized EffPac Trial.

Ulf Teichgräber, Thomas Lehmann, René Aschenbach, Dierk Scheinert, Thomas Zeller, Klaus Brechtel, Erwin Blessing, Michael Lichtenberg, Peter von Flotow, Britta Heilmeier, Sebastian Sixt, Steffen Brucks, Christian Erbel, Ulrich Beschorner, Michael Werk, Vicenç Riambau, Andreas Wienke, Christof Tobias Klumb, Markus Thieme,

Background Paclitaxel drug-coated balloon (DCB) catheter angioplasty is the preferred treatment for revascularization of femoropopliteal lesions in peripheral artery disease, but mortality is a safety concern. Purpose To assess 2-year efficacy and safety of DCB angioplasty compared with conventional balloon angioplasty (also known as plain old balloon angioplasty or POBA). ... Read more >>

Radiology (Radiology)
[2020, 295(2):478-487]

Cited: 3 times

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The IN.PACT DEEP Clinical Drug-Coated Balloon Trial: 5-Year Outcomes.

Thomas Zeller, Antonio Micari, Dierk Scheinert, Iris Baumgartner, Marc Bosiers, Frank E G Vermassen, Martin Banyai, Mehdi H Shishehbor, Hong Wang, Marianne Brodmann, ,

<h4>Objectives</h4>The goal of this study was to evaluate the 5-year follow-up data of the IN.PACT DEEP (Randomized IN.PACT Amphirion Drug-Coated Balloon [DCB] vs. Standard Percutaneous Transluminal Angioplasty [PTA] for the Treatment of Below-the-Knee Critical Limb Ischemia [CLI]) trial.<h4>Background</h4>Initial studies from randomized controlled trials have shown comparable short-term outcomes of DCB ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2020, 13(4):431-443]

Cited: 2 times

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PROMISE international; a clinical post marketing trial investigating the percutaneous deep vein arterialization (LimFlow) in the treatment of no-option chronic limb ischemia patient.

Michiel A Schreve, Michael Lichtenberg, Çagdas Ünlü, Daniela Branzan, Andrej Schmidt, Daniel A F van den Heuvel, Erwin Blessing, Marianne Brodmann, Vincent Cabane, William Tan Qing Lin, Steven Kum,

BACKGROUND:Critical limb ischemia (CLI) is the clinical end stage of peripheral artery disease and is associated with high amputation, mortality rates and poor quality of life. For CLI patients with no revascularization options, venous arterialization could be an alternative technique for limb salvage. A systematic review and meta-analysis published in ... Read more >>

CVIR Endovasc (CVIR endovascular)
[2019, 2(1):26]

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Anticoagulation in addition to dual antiplatelet therapy has no impact on long-term follow-up after endovascular treatment of (sub)acute lower limb ischemia.

Mariya Kronlage, Erwin Blessing, Oliver J Müller, Britta Heilmeier, Hugo A Katus, Christian Erbel,

<i>Background:</i> To assess the impact of short- vs. long-term anticoagulation in addition to standard dual antiplatelet therapy (DAPT) upon endovascular treatment of (sub)acute thrombembolic occlusions of the lower extremity. <i>Patient and methods:</i> Retrospective analysis was conducted on 202 patients with a thrombembolic occlusion of lower extremities, followed by crirical limb ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2019, 48(4):321-329]

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The evidence to support the use of focal force balloon technology to improve outcomes in the treatment of lower extremity arterial occlusive disease.

Erwin Blessing, Ira Lugenbiel, Andrew Holden,

Despite recent advances in endovascular therapy of lower extremity atherosclerotic disease, mainly driven through drug eluting balloon angioplasty, treatment of complex lesions remains challenging. Drug-eluting balloons work less well in heavily calcified lesions and in particular long lesions often require bail-out stenting. Lesion preparation, as a stand-alone treatment or before ... Read more >>

J Cardiovasc Surg (Torino) (The Journal of cardiovascular surgery)
[2019, 60(1):14-20]

Cited: 0 times

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First-in-Man Experience with a Novel Catheter-Based Renal Denervation System of Ultrasonic Ablation in Patients with Resistant Hypertension.

Gil Chernin, Iris Szwarcfiter, Dierk Scheinert, Erwin Blessing, Nicolas Diehm, Jo Dens, Antony Walton, Stefan Verheye, Sharad Shetty, Michael Jonas,

<h4>Purpose</h4>To report results of renal denervation (RDN) with the first catheter-based, non-balloon occlusion ultrasonic system in patients with resistant hypertension.<h4>Materials and methods</h4>In a multicenter, single-arm trial, 39 patients with resistant hypertension (defined as uncontrolled hypertension while taking ≥ 3 antihypertensive medications) were treated. The cohort consisted of 4 groups: severe ... Read more >>

J Vasc Interv Radiol (Journal of vascular and interventional radiology : JVIR)
[2018, 29(8):1158-1166]

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Renal artery anatomy assessed by quantitative analysis of selective renal angiography in 1,000 patients with hypertension.

Lucas Lauder, Sebastian Ewen, Abraham Rami Tzafriri, Elazer Reuven Edelman, Thomas Felix Lüscher, Peter J Blankenstijn, Oliver Dörr, Markus Schlaich, Faisal Sharif, Michiel Voskuil, Thomas Zeller, Christian Ukena, Bruno Scheller, Michael Böhm, Felix Mahfoud, ,

<h4>Aims</h4>With increasing attention to renovascular causes and targets for hypertension there arises a critical need for more detailed knowledge of renal arterial anatomy. However, a standardised nomenclature is lacking. The present study sought to develop a standardised nomenclature for renal anatomy considering the complexity and variation of the renal arterial ... Read more >>

EuroIntervention (EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology)
[2018, 14(1):121-128]

Cited: 2 times

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A randomized, multi-center, prospective study comparing best medical treatment versus best medical treatment plus renal artery stenting in patients with hemodynamically relevant atherosclerotic renal artery stenosis (RADAR) - one-year results of a pre-maturely terminated study.

Thomas Zeller, Hans Krankenberg, Andrejs Erglis, Erwin Blessing, Torsten Fuss, Dierk Scheinert, Ralf Weser, Beatrix B Doerr, Wilfrid D Yollo, Joerg Radermacher, ,

<h4>Background</h4>The indications for conservative "best medical treatment" (BMT) versus additional renal artery stenting are a matter of ongoing debate. The RADAR study aimed to evaluate the impact of percutaneous renal artery stenting on the impaired renal function in patients with hemodynamically significant atherosclerotic renal artery stenosis (RAS).<h4>Methods</h4>RADAR is an international, ... Read more >>

Trials (Trials)
[2017, 18(1):380]

Cited: 5 times

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Treatment of femoropopliteal lesions with the AngioSculpt scoring balloon - results from the Heidelberg PANTHER registry.

Ira Lugenbiel, Michaela Grebner, Qianxing Zhou, Anna Strothmeyer, Britta Vogel, Rita Cebola, Oliver Müller, Bernadett Brado, Marc Mittnacht, Benedikt Kohler, Hugo Katus, Erwin Blessing,

Treatment of calcified femoropopliteal lesions remains challenging, even in the era of drug-eluting balloon angioplasty. Lesion recoil and dissections after standard balloon angioplasty in calcific lesions often require subsequent stent implantation. Additionally, poor patency rates in calcified lesions despite the use of drug-eluting balloons may be due to the limited ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2018, 47(1):49-55]

Cited: 4 times

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Stellarex drug-coated balloon for treatment of femoropopliteal arterial disease-The ILLUMENATE Global Study: 12-Month results from a prospective, multicenter, single-arm study.

Herman Schroë, Andrew H Holden, Yann Goueffic, Shirley J Jansen, Patrick Peeters, Koen Keirse, Wulf Ito, Frank Vermassen, Antonio Micari, Erwin Blessing, Michael R Jaff, Thomas Zeller,

<h4>Objectives</h4>The purpose of this study was to assess the safety and performance of Stellarex Drug-coated balloon (DCB).<h4>Background</h4>DCB coatings differ in excipients, paclitaxel dose, and coating morphologies. Due to these differences, a class effect with DCBs has not been demonstrated. Consequently, each DCB needs to be evaluated independently based on its ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2018, 91(3):497-504]

Cited: 9 times

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Short and long-term results after endovascular management of vascular complications during transfemoral aortic valve implantation.

Thomas Heger, Stefanie Strauß, Erwin Blessing, Martin Andrassy, Christian Erbel, Oliver J Müller, Emmanuel Chorianopoulos, Sven Pleger, Florian Leuschner, Grigorios Korosoglou, Raffi Bekeredjian, Hugo A Katus, Britta Vogel,

Background Vascular injury and access site complications in the contemporary setting of transcatheter aortic valve implantation (TAVI) are known to be associated with increased mortality and morbidity. The aim of our study was to analyse the feasibility and safety of percutaneous treatment of such vascular complications using a stent graft. Methods Between ... Read more >>

Acta Cardiol (Acta cardiologica)
[2017, 72(4):474-482]

Cited: 1 time

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Short vs prolonged dual antiplatelet treatment upon endovascular stenting of peripheral arteries.

Mariya Kronlage, Maximilian Wassmann, Britta Vogel, Oliver J Müller, Erwin Blessing, Hugo Katus, Christian Erbel,

<h4>Introduction</h4>Peripheral artery disease (PAD) is a highly prevalent disorder with a substantial economical burden. Dual antiplatelet treatment (DAPT) upon endovascular stenting to prevent acute thrombotic reocclusions is an universally accepted practice for postinterventional management of PAD patients. However, the optimal period of time for DAPT upon endovascular stenting is not ... Read more >>

Drug Des Devel Ther (Drug design, development and therapy)
[2017, 11:2937-2945]

Cited: 1 time

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Directional Atherectomy Followed by a Paclitaxel-Coated Balloon to Inhibit Restenosis and Maintain Vessel Patency: Twelve-Month Results of the DEFINITIVE AR Study.

Thomas Zeller, Ralf Langhoff, Krishna J Rocha-Singh, Michael R Jaff, Erwin Blessing, Beatrice Amann-Vesti, Marek Krzanowski, Patrick Peeters, Dierk Scheinert, Giovanni Torsello, Sebastian Sixt, Gunnar Tepe, ,

<h4>Background</h4>Studies assessing drug-coated balloons (DCB) for the treatment of femoropopliteal artery disease are encouraging. However, challenging lesions, such as severely calcified, remain difficult to treat with DCB alone. Vessel preparation with directional atherectomy (DA) potentially improves outcomes of DCB.<h4>Methods and results</h4>DEFINITIVE AR study (Directional Atherectomy Followed by a Paclitaxel-Coated Balloon ... Read more >>

Circ Cardiovasc Interv (Circulation. Cardiovascular interventions)
[2017, 10(9):]

Cited: 23 times

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Self-Expanding Versus Balloon-Expandable Stents for Iliac Artery Occlusive Disease: The Randomized ICE Trial.

Hans Krankenberg, Thomas Zeller, Maja Ingwersen, Josefin Schmalstieg, Hans Martin Gissler, Sigrid Nikol, Iris Baumgartner, Nicolas Diehm, Estell Nickling, Stefan Müller-Hülsbeck, Rainer Schmiedel, Giovanni Torsello, Willibald Hochholzer, Christian Stelzner, Klaus Brechtel, Wulf Ito, Ralph Kickuth, Erwin Blessing, Marcus Thieme, Jaroslaw Nakonieczny, Thomas Nolte, Ragnar Gareis, Harald Boden, Sebastian Sixt,

<h4>Objectives</h4>Atherosclerosis of iliac arteries is widespread. As inflow vessels, they are of great clinical significance and increasingly being treated by endovascular means. Most commonly, stents are implanted.<h4>Background</h4>So far, due to a lack of comparative data, no guideline recommendations on the preferable stent type, balloon-expandable stent (BE) or self-expanding stent (SE), ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2017, 10(16):1694-1704]

Cited: 15 times

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A comparative study on endovascular treatment of (sub)acute critical limb ischemia: mechanical thrombectomy vs thrombolysis.

Mariya Kronlage, Ilka Printz, Britta Vogel, Erwin Blessing, Oliver J Müller, Hugo A Katus, Christian Erbel,

<h4>Objective</h4>The aim of this study was to compare different interventional methods for treatment of (sub)acute limb ischemia upon thrombotic occlusions of the lower extremity in terms of their safety and efficacy in a tertiary hospital setting.<h4>Design</h4>This is a retrospective, single-center study of non-randomized data.<h4>Methods</h4>A total of 202 patients, including 26 ... Read more >>

Drug Des Devel Ther (Drug design, development and therapy)
[2017, 11:1233-1241]

Cited: 7 times

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Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism.

Jeffrey I Weitz, Anthonie W A Lensing, Martin H Prins, Rupert Bauersachs, Jan Beyer-Westendorf, Henri Bounameaux, Timothy A Brighton, Alexander T Cohen, Bruce L Davidson, Hervé Decousus, Maria C S Freitas, Gerlind Holberg, Ajay K Kakkar, Lloyd Haskell, Bonno van Bellen, Akos F Pap, Scott D Berkowitz, Peter Verhamme, Philip S Wells, Paolo Prandoni, ,

<h4>Background</h4>Although many patients with venous thromboembolism require extended treatment, it is uncertain whether it is better to use full- or lower-intensity anticoagulation therapy or aspirin.<h4>Methods</h4>In this randomized, double-blind, phase 3 study, we assigned 3396 patients with venous thromboembolism to receive either once-daily rivaroxaban (at doses of 20 mg or 10 ... Read more >>

N Engl J Med (The New England journal of medicine)
[2017, 376(13):1211-1222]

Cited: 162 times

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