Full Text Journal Articles by
Author Ernst J Kuipers

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Clinicopathological characteristics of early onset colorectal cancer.

Fanny E R Vuik, Stella A V Nieuwenburg, Iris D Nagtegaal, Ernst J Kuipers, Manon C W Spaander,

<h4>Background</h4>The rising incidence of early onset colorectal cancer (EOCRC) might reflect a novel tumour entity.<h4>Aims</h4>To evaluate clinicopathological characteristics of sporadic EOCRC (in patients < 50 years old) and investigate changes over time METHODS: All patients with sporadic EOCRC between 1989 and 2016 were included and divided by age: 20-29 years (group I), ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, :]

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A population-based linked cohort of cancer and primary care data: A new source to study the management of cancer in primary care.

Josephina G Kuiper, Myrthe P P van Herk-Sukel, Valery E P P Lemmens, Ernst J Kuipers, Ron M C Herings,

Insight into the management of cancer in the primary care setting is pivotal to improve early recognition and survival of cancer patients. Therefore, the Netherlands Cancer Registry (NCR) was linked to the General Practitioner (GP) Database of the PHARMO Database Network to make this research possible. The NCR collects tumour ... Read more >>

Eur J Cancer Care (Engl) (European journal of cancer care)
[2021, :e13529]

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AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.

Shailja C Shah, M Blanca Piazuelo, Ernst J Kuipers, Dan Li,

<h4>Description</h4>The purpose of this Clinical Practice Update Expert Review is to provide clinicians with guidance on the diagnosis and management of atrophic gastritis, a common preneoplastic condition of the stomach, with a primary focus on atrophic gastritis due to chronic Helicobacter pylori infection-the most common etiology-or due to autoimmunity. To ... Read more >>

Gastroenterology (Gastroenterology)
[2021, 161(4):1325-1332.e7]

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Clinical Validation of a Multitarget Fecal Immunochemical Test for Colorectal Cancer Screening : A Diagnostic Test Accuracy Study.

Willemijn de Klaver, Pieter H A Wisse, Francine van Wifferen, Linda J W Bosch, Connie R Jimenez, René W M van der Hulst, Remond J A Fijneman, Ernst J Kuipers, Marjolein J E Greuter, Beatriz Carvalho, Manon C W Spaander, Evelien Dekker, Veerle M H Coupé, Meike de Wit, Gerrit A Meijer,

<h4>Background</h4>The fecal immunochemical test (FIT) is used in colorectal cancer (CRC) screening, yet it leaves room for improvement.<h4>Objective</h4>To develop a multitarget FIT (mtFIT) with better diagnostic performance than FIT.<h4>Design</h4>Diagnostic test accuracy study.<h4>Setting</h4>Colonoscopy-controlled series.<h4>Participants</h4>Persons (<i>n</i> = 1284) from a screening (<i>n</i> = 1038) and referral (<i>n</i> = 246) population were classified ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2021, 174(9):1224-1231]

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A steep increase in healthcare seeking behaviour in the last months before colorectal cancer diagnosis.

Josephina G Kuiper, Myrthe P P van Herk-Sukel, Valery E P P Lemmens, Ernst J Kuipers, Ron M C Herings,

<h4>Background</h4>Timely recognition of colorectal cancer related symptoms is essential to reduce time to diagnosis. This study aims to investigate the primary healthcare use preceding a colorectal cancer diagnosis.<h4>Methods</h4>From a cohort of linked cancer and primary care data, patients diagnosed with primary colorectal cancer in the period 2007-2014 were selected and ... Read more >>

BMC Fam Pract (BMC family practice)
[2021, 22(1):121]

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Clinicopathological features and risk factors for developing colorectal neoplasia in Hodgkin's lymphoma survivors.

Berbel L M Ykema, Lisanne S Rigter, Manon C W Spaander, Leon M G Moons, Tanya M Bisseling, Berthe M P Aleman, Evelien Dekker, Wieke H M Verbeek, Ernst J Kuipers, Jan Paul de Boer, Pieternella J Lugtenburg, Cecile P M Janus, Eefke J Petersen, Judith M Roesink, Richard W M van der Maazen, Gerrit A Meijer, Michael Schaapveld, Flora E van Leeuwen, Beatriz Carvalho, Petur Snaebjornsson, Monique E van Leerdam,

<h4>Background</h4>Hodgkin's lymphoma (HL) survivors treated with abdominal radiotherapy and/or procarbazine have an increased risk of developing colorectal neoplasia.<h4>Aims</h4>We evaluated the clinicopathological characteristics and risk factors for developing (advanced) neoplasia (AN) in HL survivors.<h4>Methods</h4>In all, 101 HL survivors (median age 51 years, median age of HL diagnosis 25 years) underwent colonoscopy and 350 ... Read more >>

Dig Endosc (Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society)
[2021, :]

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Editorial: machine learning models for gastric cancer risk prediction.

Manon C W Spaander, Ernst J Kuipers,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 53(8):943-944]

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Towards personalised management for non-variceal upper gastrointestinal bleeding.

Joseph J Y Sung, Loren Laine, Ernst J Kuipers, Alan N Barkun,

Guidelines from national and international professional societies on upper gastrointestinal bleeding highlight the important clinical issues but do not always identify specific management strategies pertaining to individual patients. Optimal treatment should consider the personal needs of an individual patient and the pertinent resources and experience available at the point of ... Read more >>

Gut (Gut)
[2021, 70(5):818-824]

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Factors associated with the progression of gastric intestinal metaplasia: a multicenter, prospective cohort study.

S A V Nieuwenburg, M C Mommersteeg, E L Eikenboom, B Yu, W J den Hollander, I Lisanne Holster, Caroline M den Hoed, L G Capelle, Thjon J Tang, Marie-Paule Anten, I Prytz-Berset, E M Witteman, F Ter Borg, Jordy P W Burger, Marco J Bruno, G M Fuhler, Maikel P Peppelenbosch, Michael Doukas, Ernst J Kuipers, Manon C W Spaander,

<b>Background and study aims </b> Gastric cancer (GC) is usually preceded by premalignant gastric lesions (GPLs) such as gastric intestinal metaplasia (GIM). Information on risk factors associated with neoplastic progression of GIM are scarce. This study aimed to identify predictors for progression of GIM in areas with low GC incidence. <b>Patients ... Read more >>

Endosc Int Open (Endoscopy international open)
[2021, 9(3):E297-E305]

Cited: 1 time

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Accuracy of upper endoscopies with random biopsies to identify patients with gastric premalignant lesions who can safely be exempt from surveillance.

Michiel C Mommersteeg, Stella A V Nieuwenburg, Wouter J den Hollander, Lisanne Holster, Caroline M den Hoed, Lisette G Capelle, Tjon J Tang, Marie- Paule Anten, Ingrid Prytz-Berset, Ellen M Witteman, Frank Ter Borg, Jordy P W Burger, Michail Doukas, Marco J Bruno, Maikel P Peppelenbosch, Gwenny M Fuhler, Ernst J Kuipers, Manon C W Spaander,

<h4>Introduction</h4>Guidelines recommend endoscopy with biopsies to stratify patients with gastric premalignant lesions (GPL) to high and low progression risk. High-risk patients are recommended to undergo surveillance. We aimed to assess the accuracy of guideline recommendations to identify low-risk patients, who can safely be discharged from surveillance.<h4>Methods</h4>This study includes patients with ... Read more >>

Gastric Cancer (Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association)
[2021, 24(3):680-690]

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Colon capsule endoscopy in colorectal cancer screening: a systematic review.

Fanny E R Vuik, Stella A V Nieuwenburg, Sarah Moen, Cristiano Spada, Carlo Senore, Cesare Hassan, Marco Pennazio, Emanuele Rondonotti, Silvia Pecere, Ernst J Kuipers, Manon C W Spaander,

<h4>Introduction</h4>Primary colonoscopy and fecal immunochemical test (FIT) are the most commonly used colorectal cancer (CRC) screening modalities. Colon capsule endoscopy (CCE) might be an alternative. Data on the performance of CCE as a CRC screening tool in a screening population remain scarce. This is the first systematic review to provide ... Read more >>

Endoscopy (Endoscopy)
[2021, 53(8):815-824]

Cited: 2 times

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The impact of the temporary suspension of national cancer screening programmes due to the COVID-19 epidemic on the diagnosis of breast and colorectal cancer in the Netherlands.

Avinash G Dinmohamed, Matteo Cellamare, Otto Visser, Linda de Munck, Marloes A G Elferink, Pieter J Westenend, Jelle Wesseling, Mireille J M Broeders, Ernst J Kuipers, Matthias A W Merkx, Iris D Nagtegaal, Sabine Siesling,

Oncological care was largely derailed due to the reprioritisation of health care services to handle the initial surge of COVID-19 patients adequately. Cancer screening programmes were no exception in this reprioritisation. They were temporarily halted in the Netherlands (1) to alleviate the pressure on health care services overwhelmed by the ... Read more >>

J Hematol Oncol (Journal of hematology & oncology)
[2020, 13(1):147]

Cited: 16 times

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Population-Based Prevalence of Gastrointestinal Abnormalities at Colon Capsule Endoscopy.

Fanny E R Vuik, Stella A V Nieuwenburg, Sarah Moen, Eline H Schreuders, Marinka D Oudkerk Pool, Elisabeth F P Peterse, Cristiano Spada, Owen Epstein, Ignacio Fernández-Urién, Albert Hofman, Ernst J Kuipers, Manon C W Spaander,

<h4>Background & aims</h4>The population prevalence of gastrointestinal (GI) disease is unclear and difficult to assess in an asymptomatic population. The aim of this study was to determine prevalence of GI lesions in a largely asymptomatic population undergoing colon capsule endoscopy (CCE).<h4>Methods</h4>Participants aged between 50-75 years were retrieved from the Rotterdam ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2020, :]

Cited: 1 time

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Colorectal Cancer Screening in the Novel Coronavirus Disease-2019 Era.

Evelien Dekker, Han-Mo Chiu, Iris Lansdorp-Vogelaar, ,

Gastroenterology (Gastroenterology)
[2020, 159(6):1998-2003]

Cited: 3 times

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Colonoscopy-Related Mortality in a Fecal Immunochemical Test-Based Colorectal Cancer Screening Program.

Arthur I Kooyker, Esther Toes-Zoutendijk, Annemieke W J Opstal-van Winden, Maaike Buskermolen, Hanneke J van Vuuren, Ernst J Kuipers, Folkert J van Kemenade, Chris Ramakers, Evelien Dekker, Iris D Nagtegaal, Harry J de Koning, Manon C W Spaander, Iris Lansdorp-Vogelaar, Monique E van Leerdam,

<h4>Background & aims</h4>Many countries have introduced colorectal cancer (CRC) screening programs with fecal immunochemical tests (FITs), and follow-up colonoscopies for individuals with a positive FIT result. In order to make an informed decision to participate, individuals must be informed about the benefits and harms of FIT-based screening and subsequent colonoscopy. ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, 19(7):1418-1425]

Cited: 0 times

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Recent advances in the detection and management of early gastric cancer and its precursors.

William Waddingham, Stella A V Nieuwenburg, Sean Carlson, Manuel Rodriguez-Justo, Manon Spaander, Ernst J Kuipers, Marnix Jansen, David G Graham, Matthew Banks,

Despite declines in incidence, gastric cancer remains a disease with a poor prognosis and limited treatment options due to its often late stage of diagnosis. In contrast, early gastric cancer has a good to excellent prognosis, with 5-year survival rates as high as 92.6% after endoscopic resection. There remains an ... Read more >>

Frontline Gastroenterol (Frontline gastroenterology)
[2021, 12(4):322-331]

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Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression.

Malgorzata A Komor, Linda Jw Bosch, Veerle Mh Coupé, Christian Rausch, Thang V Pham, Sander R Piersma, Sandra Mongera, Chris Jj Mulder, Evelien Dekker, Ernst J Kuipers, Mark A van de Wiel, Beatriz Carvalho, Remond Ja Fijneman, Connie R Jimenez, Gerrit A Meijer, Meike de Wit,

Screening to detect colorectal cancer (CRC) in an early or premalignant state is an effective method to reduce CRC mortality rates. Current stool-based screening tests, e.g. fecal immunochemical test (FIT), have a suboptimal sensitivity for colorectal adenomas and difficulty distinguishing adenomas at high risk of progressing to cancer from those ... Read more >>

J Pathol (The Journal of pathology)
[2020, 250(3):288-298]

Cited: 5 times

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How to Manage a Patient With Gastric Intestinal Metaplasia: An International Perspective.

Mário Dinis-Ribeiro, Ernst J Kuipers,

Gastroenterology (Gastroenterology)
[2020, 158(6):1534-1537]

Cited: 3 times

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The second round of the Dutch colorectal cancer screening program: Impact of an increased fecal immunochemical test cut-off level on yield of screening.

Arthur I Kooyker, Esther Toes-Zoutendijk, Annemieke W J Opstal-van Winden, Manon C W Spaander, Maaike Buskermolen, Hanneke J van Vuuren, Ernst J Kuipers, Folkert J van Kemenade, Chris Ramakers, Maarten G J Thomeer, Evelien Dekker, Iris D Nagtegaal, Harry J de Koning, Monique E van Leerdam, Iris Lansdorp-Vogelaar,

The Dutch colorectal cancer (CRC) screening program started in 2014, inviting the target population biennially to perform a fecal immunochemical test (FIT). We obtained prospectively collected data from the national screening information-system to present the results of the second round (2016) and evaluate the impact of increasing the FIT cut-off ... Read more >>

Int J Cancer (International journal of cancer)
[2020, 147(4):1098-1106]

Cited: 5 times

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First steps towards combining faecal immunochemical testing with the gut microbiome in colorectal cancer screening.

Esmée J Grobbee, Suk Yee Lam, Gwenny M Fuhler, Blerdi Blakaj, Sergey R Konstantinov, Marco J Bruno, Maikel P Peppelenbosch, Ernst J Kuipers, Manon Cw Spaander,

<h4>Objectives</h4>Many countries use faecal immunochemical testing (FIT) to screen for colorectal cancer. There is increasing evidence that faecal microbiota play a crucial role in colorectal cancer carcinogenesis. We assessed the possibility of measuring faecal microbial features in FIT as potential future biomarkers in colorectal cancer screening.<h4>Methods</h4>Bacterial stability over time and ... Read more >>

United European Gastroenterol J (United European gastroenterology journal)
[2020, 8(3):293-302]

Cited: 3 times

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Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations From the International Consensus Group.

Alan N Barkun, Majid Almadi, Ernst J Kuipers, Loren Laine, Joseph Sung, Frances Tse, Grigorios I Leontiadis, Neena S Abraham, Xavier Calvet, Francis K L Chan, James Douketis, Robert Enns, Ian M Gralnek, Vipul Jairath, Dennis Jensen, James Lau, Gregory Y H Lip, Romaric Loffroy, Fauze Maluf-Filho, Andrew C Meltzer, Nageshwar Reddy, John R Saltzman, John K Marshall, Marc Bardou,

Description:This update of the 2010 International Consensus Recommendations on the Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding (UGIB) refines previous important statements and presents new clinically relevant recommendations. Methods:An international multidisciplinary group of experts developed the recommendations. Data sources included evidence summarized in previous recommendations, as well as systematic ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2019, 171(11):805-822]

Cited: 29 times

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The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

,

BACKGROUND:Data about the global, regional, and country-specific variations in the levels and trends of colorectal cancer are required to understand the impact of this disease and the trends in its burden to help policy makers allocate resources. Here we provide a status report on the incidence, mortality, and disability caused ... Read more >>

Lancet Gastroenterol Hepatol (The lancet. Gastroenterology & hepatology)
[2019, 4(12):913-933]

Cited: 56 times

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Personalised screening for colorectal cancer, ready for take-off.

Ernst J Kuipers, Esmée J Grobbee,

Gut (Gut)
[2020, 69(3):403-404]

Cited: 1 time

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Incidence of Interval Colorectal Cancer After Negative Results From First-Round Fecal Immunochemical Screening Tests, by Cutoff Value and Participant Sex and Age.

Esther Toes-Zoutendijk, Arthur I Kooyker, Evelien Dekker, Manon C W Spaander, Annemieke W J Opstal-van Winden, Christian Ramakers, Maaike Buskermolen, Anneke J van Vuuren, Ernst J Kuipers, Folkert J van Kemenade, Marie-Louise F Velthuysen, Maarten G J Thomeer, Harriët van Veldhuizen, Marjolein van Ballegooijen, Iris D Nagtegaal, Harry J de Koning, Monique E van Leerdam, Iris Lansdorp-Vogelaar, ,

<h4>Background & aims</h4>We evaluated the incidence of interval cancers between the first and second rounds of colorectal cancer (CRC) screening with the FOB-Gold fecal immunochemical test (FIT), and the effects of different cutoff values and patient sex and age.<h4>Methods</h4>We collected data from participants in a population-based CRC screening program in ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2020, 18(7):1493-1500]

Cited: 6 times

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Accuracy of endoscopic staging and targeted biopsies for routine gastric intestinal metaplasia and gastric atrophy evaluation study protocol of a prospective, cohort study: the estimate study.

Stella A V Nieuwenburg, William W Waddingham, David Graham, Manuel Rodriguez-Justo, Katharina Biermann, Ernst J Kuipers, Matthew Banks, Marnix Jansen, Manon C W Spaander,

<h4>Introduction</h4>Patients with chronic atrophic gastritis (CAG) and intestinal metaplasia (IM) are at risk of developing gastric adenocarcinoma. Their diagnosis and management currently rely on histopathological guidance after random endoscopic biopsy sampling (Sydney biopsy strategy). This approach has significant flaws such as under-diagnosis, poor reproducibility and poor correlation between endoscopy and ... Read more >>

BMJ Open (BMJ open)
[2019, 9(9):e032013]

Cited: 0 times

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