Full Text Journal Articles by
Author Erika Gromnica Ihle

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[People with inflammatory rheumatic diseases need an interdisciplinary care team].

Rotraut Schmale-Grede, Erika Gromnica-Ihle, Ursula Faubel,

Orthopade (Der Orthopade)
[2019, 48(11):900-901]

Cited: 0 times

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Indication Criteria for Total Knee Arthroplasty in Patients with Osteoarthritis - A Multi-perspective Consensus Study.

Jochen Schmitt, Toni Lange, Klaus-Peter Günther, Christian Kopkow, Elisabeth Rataj, Christian Apfelbacher, Martin Aringer, Eckhardt Böhle, Hartmut Bork, Karsten Dreinhöfer, Niklaus Friederich, Karl-Heinz Frosch, Sascha Gravius, Erika Gromnica-Ihle, Karl-Dieter Heller, Stephan Kirschner, Bernd Kladny, Hendrik Kohlhof, Michael Kremer, Nicolai Leuchten, Maike Lippmann, Jürgen Malzahn, Heiko Meyer, Rainer Sabatowski, Hanns-Peter Scharf, Johannes Stoeve, Richard Wagner, Jörg Lützner,

<b>Background and Objectives</b> Knee osteoarthritis (OA) is a significant public health burden. Rates of total knee arthroplasty (TKA) in OA vary substantially between geographical regions, most likely due to the lack of standardised indication criteria. We set out to define indication criteria for the German healthcare system for TKA in ... Read more >>

Z Orthop Unfall (Zeitschrift fur Orthopadie und Unfallchirurgie)
[2017, 155(5):539-548]

Cited: 13 times

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Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients.

R Cervera, R Serrano, G J Pons-Estel, L Ceberio-Hualde, Y Shoenfeld, E de Ramón, V Buonaiuto, S Jacobsen, M M Zeher, T Tarr, A Tincani, M Taglietti, G Theodossiades, E Nomikou, M Galeazzi, F Bellisai, P L Meroni, R H W M Derksen, P G D de Groot, M Baleva, M Mosca, S Bombardieri, F Houssiau, J-C Gris, I Quéré, E Hachulla, C Vasconcelos, A Fernández-Nebro, M Haro, Z Amoura, M Miyara, M Tektonidou, G Espinosa, M L Bertolaccini, M A Khamashta, ,

<h4>Objectives</h4>To assess the prevalence of the main causes of morbi-mortality in the antiphospholipid syndrome (APS) during a 10-year-follow-up period and to compare the frequency of early manifestations with those that appeared later.<h4>Methods</h4>In 1999, we started an observational study of 1000 APS patients from 13 European countries. All had medical histories ... Read more >>

Ann Rheum Dis (Annals of the rheumatic diseases)
[2015, 74(6):1011-1018]

Cited: 163 times

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German guidelines for the sequential medical treatment of rheumatoid arthritis with traditional and biologic disease-modifying antirheumatic drugs.

Katinka Albrecht, Klaus Krüger, Jürgen Wollenhaupt, Rieke Alten, Marina Backhaus, Christoph Baerwald, Wolfgang Bolten, Jürgen Braun, Harald Burkhardt, Gerd R Burmester, Markus Gaubitz, Angela Gause, Erika Gromnica-Ihle, Herbert Kellner, Jens Kuipers, Andreas Krause, Hans-Martin Lorenz, Bernhard Manger, Hubert Nüßlein, Hans-Georg Pott, Andrea Rubbert-Roth, Matthias Schneider, Christof Specker, Hendrik Schulze-Koops, Hans-Peter Tony, Siegfried Wassenberg, Ulf Müller-Ladner, ,

The German Society of Rheumatology approved new German guidelines for the sequential medical treatment of rheumatoid arthritis (RA) based on the European League Against Rheumatism (EULAR) recommendations for the management of RA published in 2010. An update of the EULAR systematic literature research was performed in Medline, Embase, and Cochrane ... Read more >>

Rheumatol Int (Rheumatology international)
[2014, 34(1):1-9]

Cited: 17 times

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Clinical presentation, burden of disease and treatment in young-onset and late-onset rheumatoid arthritis: a matched-pairs analysis taking age and disease duration into account.

Dörte Huscher, Claudia Sengler, Erika Gromnica-Ihle, Sascha Bischoff, Thorsten Eidner, Wolfgang Ochs, Jutta Richter, Angela Zink,

<h4>Objectives</h4>The aim of this study is to compare clinical features and treatment of young onset rheumatoid arthritis with late-onset rheumatoid arthritis.<h4>Methods</h4>Nine thousand five hundred forty-one patients with rheumatoid arthritis (RA) enrolled in the national database of the German Collaborative Arthritis Centres in 2007-2009 were stratified by age at disease onset: ... Read more >>

Clin Exp Rheumatol (Clinical and experimental rheumatology)
[2013, 31(2):256-262]

Cited: 21 times

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Hypothalamus-pituitary-adrenal axis function in patients with rheumatoid arthritis treated with nighttime-release prednisone.

Rieke Alten, Gisela Döring, Maurizio Cutolo, Erika Gromnica-Ihle, Stephan Witte, Rainer Straub, Frank Buttgereit,

<h4>Objective</h4>To investigate the effects of longterm low-dose chronotherapy with modified-release (MR) prednisone for rheumatoid arthritis (RA) on the hypothalamus-pituitary-adrenal (HPA) axis as part of the Circadian Administration of Prednisone in Rheumatoid Arthritis (CAPRA-1) study. This consisted of a 3-month active-controlled phase and a 9-month open-label extension with MR prednisone including ... Read more >>

J Rheumatol (The Journal of rheumatology)
[2010, 37(10):2025-2031]

Cited: 38 times

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Targeting pathophysiological rhythms: prednisone chronotherapy shows sustained efficacy in rheumatoid arthritis.

Frank Buttgereit, Gisela Doering, Achim Schaeffler, Stephan Witte, Stanislaw Sierakowski, Erika Gromnica-Ihle, Slawomir Jeka, Klaus Krueger, Jacek Szechinski, Rieke Alten,

<h4>Objective</h4>This 9-month open-label extension of the Circadian Administration of Prednisone in Rheumatoid Arthritis Study (CAPRA 1) investigated the long-term safety and efficacy of prednisone chronotherapy with a novel modified-release (MR) prednisone for up to 12 months.<h4>Methods</h4>Of 288 patients with rheumatoid arthritis originally randomised to MR or immediate-release (IR) prednisone, 249 ... Read more >>

Ann Rheum Dis (Annals of the rheumatic diseases)
[2010, 69(7):1275-1280]

Cited: 50 times

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Association of an NKG2D gene variant with systemic lupus erythematosus in two populations.

Gamze Kabalak, Rachel M Thomas, Javier Martin, Noberto Ortego-Centeno, Juan Jimenez-Alonso, Enrique de Ramón, Sabine Buyny, Sandra Hamsen, Wolfgang L Gross, Sebastian Schnarr, Henning Zeidler, Erika Gromnica-Ihle, Reinhold E Schmidt, Torsten Witte,

NKG2D, involved in T-cell activation and viral defense, shows a single-nucleotide polymorphism (SNP) in the transmembrane region, characterized by a substitution of alanine with threonine. We examined the association of systemic lupus erythematosus (SLE) with one of the NKG2D gene variants. We also studied the functional impact of that allele ... Read more >>

Hum Immunol (Human immunology)
[2010, 71(1):74-78]

Cited: 9 times

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Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans.

Kui Liu, Quan-Zhen Li, Angelica M Delgado-Vega, Anna-Karin Abelson, Elena Sánchez, Jennifer A Kelly, Li Li, Yang Liu, Jinchun Zhou, Mei Yan, Qiu Ye, Shenxi Liu, Chun Xie, Xin J Zhou, Sharon A Chung, Bernardo Pons-Estel, Torsten Witte, Enrique de Ramón, Sang-Cheol Bae, Nadia Barizzone, Gian Domenico Sebastiani, Joan T Merrill, Peter K Gregersen, Gary G Gilkeson, Robert P Kimberly, Timothy J Vyse, Il Kim, Sandra D'Alfonso, Javier Martin, John B Harley, Lindsey A Criswell, , , , , , , Edward K Wakeland, Marta E Alarcón-Riquelme, Chandra Mohan,

Immune-mediated nephritis contributes to disease in systemic lupus erythematosus, Goodpasture syndrome (caused by antibodies specific for glomerular basement membrane [anti-GBM antibodies]), and spontaneous lupus nephritis. Inbred mouse strains differ in susceptibility to anti-GBM antibody-induced and spontaneous lupus nephritis. This study sought to clarify the genetic and molecular factors that maybe ... Read more >>

J Clin Invest (The Journal of clinical investigation)
[2009, 119(4):911-923]

Cited: 75 times

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Ultrasonography of salivary glands -- a highly specific imaging procedure for diagnosis of Sjögren's syndrome.

Dirk Wernicke, Heidemarie Hess, Erika Gromnica-Ihle, Andreas Krause, Wolfgang A Schmidt,

<h4>Objective</h4>To verify ultrasonographic criteria for examination of the major salivary glands in diagnosis of primary and secondary Sjögren's syndrome (SS).<h4>Methods</h4>Three hundred sixteen consecutive patients with rheumatic diseases were selected according to the European Consensus Study Group diagnostic criteria for SS. Fifty-seven had primary SS, 33 had secondary SS, 78 had ... Read more >>

J Rheumatol (The Journal of rheumatology)
[2008, 35(2):285-293]

Cited: 41 times

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Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system.

Tobias Alexander, Andreas Thiel, Oliver Rosen, Gero Massenkeil, Arne Sattler, Siegfried Kohler, Henrik Mei, Hartmut Radtke, Erika Gromnica-Ihle, Gerd-Rüdiger Burmester, Renate Arnold, Andreas Radbruch, Falk Hiepe,

Clinical trials have indicated that immunoablation followed by autologous hematopoietic stem cell transplantation (ASCT) has the potential to induce clinical remission in patients with refractory systemic lupus erythematosus (SLE), but the mechanisms have remained unclear. We now report the results of a single-center prospective study of long-term immune reconstitution after ... Read more >>

Blood (Blood)
[2009, 113(1):214-223]

Cited: 147 times

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Direct assessment of thymic reactivation after autologous stem cell transplantation.

Andreas Thiel, Tobias Alexander, Christian A Schmidt, Gregorsz K Przybylski, Sonja Kimmig, Siegfried Kohler, Hartmut Radtke, Erika Gromnica-Ihle, Gero Massenkeil, Andreas Radbruch, Renate Arnold, Falk Hiepe,

Methods to quantify Th cell reconstitution after immunosuppressive therapies such as hematopoietic stem cell transplantation are becoming a key issue since persistent Th cell deficiencies may result in severe complications and adverse events. We employed here cytometric monitoring of CD31+ thymus-naive Th cells for the direct assessment of human thymic ... Read more >>

Acta Haematol (Acta haematologica)
[2008, 119(1):22-27]

Cited: 21 times

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Do temporal artery duplex ultrasound findings correlate with ophthalmic complications in giant cell arteritis?

Wolfgang A Schmidt, Andreas Krause, Bernd Schicke, Jörn Kuchenbecker, Erika Gromnica-Ihle,

<h4>Objective</h4>Ophthalmic complications are common in acute GCA. Do temporal artery ultrasound and clinical parameters correlate with the occurrence and severity of ophthalmic complications?<h4>Methods</h4>The results of temporal artery ultrasound examinations are compared with the occurrence of anterior ischaemic optic neuropathy (AION), central retinal artery occlusion (CRAO), branch retinal artery occlusion (BRAO), ... Read more >>

Rheumatology (Oxford) (Rheumatology (Oxford, England))
[2009, 48(4):383-385]

Cited: 17 times

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Alefacept with methotrexate for treatment of psoriatic arthritis: open-label extension of a randomized, double-blind, placebo-controlled study.

Philip J Mease, Kristian Reich, ,

<h4>Background</h4>A single course of alefacept intramuscularly in combination with methotrexate (MTX) was effective in treating both psoriasis and psoriatic arthritis (PsA).<h4>Objective</h4>We sought to determine the efficacy and safety of an additional course of alefacept intramuscularly in combination with MTX in patients with PsA.<h4>Methods</h4>In this open-label extension study, patients with PsA ... Read more >>

J Am Acad Dermatol (Journal of the American Academy of Dermatology)
[2009, 60(3):402-411]

Cited: 24 times

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Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): a double-blind, randomised controlled trial.

Frank Buttgereit, Gisela Doering, Achim Schaeffler, Stephan Witte, Stanislaw Sierakowski, Erika Gromnica-Ihle, Slawomir Jeka, Klaus Krueger, Jacek Szechinski, Rieke Alten,

<h4>Background</h4>Circadian rhythms are changed in patients with rheumatoid arthritis. A new modified-release delivery system has been developed which adapts the release of the administered glucocorticoid to the circadian rhythms of endogenous cortisol and disease symptoms to improve the benefit-risk ratio of glucocorticoid therapy in rheumatoid arthritis. We aimed to assess ... Read more >>

Lancet (Lancet (London, England))
[2008, 371(9608):205-214]

Cited: 150 times

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Safety and efficacy of readministration of infliximab after longterm continuous therapy and withdrawal in patients with ankylosing spondylitis.

Xenofon Baraliakos, Joachim Listing, Martin Rudwaleit, Jan Brandt, Rieke Alten, Gerd Burmester, Erika Gromnica-Ihle, Hildrun Haibel, Stephan Schewe, Matthias Schneider, Helmut Sörensen, Henning Zeidler, Sudha Visvanathan, Joachim Sieper, Juergen Braun,

<h4>Objective</h4>To analyze the safety and efficacy of the anti-tumor necrosis factor agent infliximab in patients with ankylosing spondylitis (AS) after discontinuation of longterm therapy over 1 year and readministration, using clinical and laboratory assessments including serum levels of antibodies to infliximab (ATI).<h4>Methods</h4>Altogether 42/43 patients with AS in a 3-year multicenter ... Read more >>

J Rheumatol (The Journal of rheumatology)
[2007, 34(3):510-515]

Cited: 32 times

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The expression of collagenase 3 (MMP-13) mRNA in the synovial tissue is associated with histopathologic type II synovitis in rheumatoid arthritis.

Dirk Wernicke, Christine Seyfert, Erika Gromnica-Ihle, Peter Stiehl,

The histopathologic analysis of the synovial tissue is important to distinguish rheumatoid arthritis (RA) from other forms of synovitis and to provide information about prognosis and therapeutic strategies at early stages of the disease. In this context, the present study was performed to investigate the correlation between immunohistopathological and morphological ... Read more >>

Autoimmunity (Autoimmunity)
[2006, 39(4):307-313]

Cited: 23 times

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Infections in patients with rheumatoid arthritis treated with biologic agents.

Joachim Listing, Anja Strangfeld, Sonja Kary, Rolf Rau, Ulrich von Hinueber, Maria Stoyanova-Scholz, Erika Gromnica-Ihle, Christian Antoni, Peter Herzer, Jörn Kekow, Matthias Schneider, Angela Zink,

<h4>Objective</h4>To estimate the incidence rates of serious and nonserious infections in patients with rheumatoid arthritis (RA) who start treatment with a biologic agent, and to compare these rates with those in patients with RA who receive conventional treatment.<h4>Methods</h4>Patients enrolled in the German biologics register between May 2001 and September 2003 ... Read more >>

Arthritis Rheum (Arthritis and rheumatism)
[2005, 52(11):3403-3412]

Cited: 348 times

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Clinical and functional remission: even though biologics are superior to conventional DMARDs overall success rates remain low--results from RABBIT, the German biologics register.

Joachim Listing, Anja Strangfeld, Rolf Rau, Jörn Kekow, Erika Gromnica-Ihle, Thilo Klopsch, Winfried Demary, Gerd-Rüdiger Burmester, Angela Zink,

We investigated the frequency of remission according to the disease activity score (DAS28) definition, modified American Rheumatology Association (ARA) criteria, and the frequency of an achievement of a functional status above defined thresholds ('functional remission', 'physical independence') in rheumatoid arthritis (RA) patients treated with either biologics or conventional DMARDs. We ... Read more >>

Arthritis Res Ther (Arthritis research & therapy)
[2006, 8(3):R66]

Cited: 97 times

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Manifestation of rheumatoid arthritis in a patient with hereditary haemochromatosis.

Dirk Wernicke, Eva Seipelt, Wolfgang A Schmidt, Erika Gromnica-Ihle,

Articular symptoms are frequent manifestations of hereditary haemochromatosis. The clinical signs of the arthropathy of haemochromatosis are not specific and difficult to identify in case of co-incidence of haemochromatosis with Heberden's and Bouchard's osteoarthritis or rheumatoid arthritis (RA). Here the manifestation of RA in a patient is reported who was ... Read more >>

Rheumatol Int (Rheumatology international)
[2006, 26(10):939-941]

Cited: 3 times

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Healthcare and burden of disease in psoriatic arthritis. A comparison with rheumatoid arthritis and ankylosing spondylitis.

Angela Zink, Katja Thiele, Doerte Huscher, Joachim Listing, Joachim Sieper, Andreas Krause, Erika Gromnica-Ihle, Ulrich von Hinueber, Siegfried Wassenberg, Ekkehard Genth, Matthias Schneider, ,

<h4>Objective</h4>To compare quality of life and treatment among patients with psoriatic arthritis (PsA), rheumatoid arthritis (RA), and ankylosing spondylitis (AS) treated by German rheumatologists.<h4>Methods</h4>Data for outpatients with PsA (n = 1863), RA (n = 9627), or AS (n = 1378) enrolled in the national database of the German collaborative arthritis ... Read more >>

J Rheumatol (The Journal of rheumatology)
[2006, 33(1):86-90]

Cited: 63 times

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What is the best approach to diagnosing large-vessel vasculitis?

Wolfgang A Schmidt, Erika Gromnica-Ihle,

Temporal arteritis, including large-vessel giant cell arteritis, and Takayasu's arteritis are the two primary large-vessel vasculitides. Patients with temporal arteritis often present with headache, swollen temporal arteries, impairment of vision or symptoms of polymyalgia rheumatica. Clinical examination includes palpation of the temporal arteries and radial pulses, auscultation of the subclavian ... Read more >>

Best Pract Res Clin Rheumatol (Best practice & research. Clinical rheumatology)
[2005, 19(2):223-242]

Cited: 31 times

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Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab.

Xenofon Baraliakos, Joachim Listing, Jan Brandt, Angela Zink, Rieke Alten, Gerd Burmester, Erika Gromnica-Ihle, Herbert Kellner, Matthias Schneider, Helmut Sörensen, Henning Zeidler, Martin Rudwaleit, Joachim Sieper, Juergen Braun,

We analyzed the clinical response and the time to relapse after discontinuation of continuous long-term infliximab therapy in patients with ankylosing spondylitis (AS). After 3 years of infliximab therapy, all AS patients (n = 42) discontinued treatment (time point (TP)1) and were visited regularly for 1 year in order to ... Read more >>

Arthritis Res Ther (Arthritis research & therapy)
[2005, 7(3):R439-44]

Cited: 121 times

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Modelling cost effectiveness and cost utility of sequential DMARD therapy including leflunomide for rheumatoid arthritis in Germany: II. The contribution of leflunomide to efficiency.

Peter K Schädlich, Henning Zeidler, Angela Zink, Erika Gromnica-Ihle, Matthias Schneider, Christoph Straub, Josef G Brecht, Eduard Huppertz,

<h4>Objective</h4>To estimate the 3-year incremental cost effectiveness and cost utility of introducing leflunomide into sequential therapy, consisting of the most frequently used disease-modifying antirheumatic drugs (DMARDs), for patients with rheumatoid arthritis in specialised, i.e. rheumatological, care in Germany.<h4>Design and setting</h4>The analysis was conducted from the societal perspective in Germany using ... Read more >>

Pharmacoeconomics (PharmacoEconomics)
[2005, 23(4):395-420]

Cited: 9 times

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Correction: Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab

Xenofon Baraliakos, Joachim Listing, Jan Brandt, Angela Zink, Rieke Alten, Gerd Burmester, Erika Gromnica-Ihle, Herbert Kellner, Matthias Schneider, Helmut Sörensen, Hennig Zeidler, Martin Rudwaleit, Joachim Sieper, Juergen Braun,

Arthritis Res Ther (Arthritis research & therapy)
[2005, 7(3):113-113]

Cited: 2 times

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