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Author Emma Fransson


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Optimal protocols for sequence-based characterization of the human vaginal microbiome

Luisa Hugerth, Marcela Pereira, Yinghua Zha, Maike Seifert, Vilde Kaldhusdal, Fredrik Boulund, Maria Krog, Zahra Bashir, Marica Hamsten, Emma Fransson, Henriette Svarre-Nielsen, Ina Schuppe-Koistinen, Lars Engstrand,

Abstract The vaginal microbiome has been connected to a wide range of health outcomes. This has led to a thriving research environment, but also to the use of conflicting methodologies to study its microbial composition. Here we systematically assess best practices for the sequencing-based characterization of the human vaginal microbiome. ... Read more >>

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Child living arrangements following separation and mental health of parents in Sweden.

Sara Fritzell, Michael Gähler, Emma Fransson,

Father involvement and joint physical custody in post-separation families are increasingly common. In Sweden, 35 percent of the children of separated parents live equally much with both parents. Since parenthood is gendered, the associations between child living arrangement and parental health may vary between women and men. This study analyzes ... Read more >>

SSM Popul Health (SSM - population health)
[2020, 10:100511]

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Cohort profile: the Biology, Affect, Stress, Imaging and Cognition (BASIC) study on perinatal depression in a population-based Swedish cohort.

Cathrine Axfors, Emma Bränn, Hanna E Henriksson, Charlotte Hellgren, Theodora Kunovac Kallak, Emma Fransson, Susanne Lager, Stavros I Iliadis, Sara Sylvén, Fotios C Papadopoulos, Lisa Ekselius, Inger Sundström-Poromaa, Alkistis Skalkidou,

PURPOSE:With the population-based, prospective Biology, Affect, Stress, Imaging and Cognition (BASIC) cohort, we aim to investigate the biopsychosocial aetiological processes involved in perinatal depression (PND) and to pinpoint its predictors in order to improve early detection. PARTICIPANTS:From September 2009 to November 2018, the BASIC study at Uppsala University Hospital, Sweden, ... Read more >>

BMJ Open (BMJ open)
[2019, 9(10):e031514]

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"We also communicate through a book in the diaper bag"-Separated parents´ ways to coparent and promote adaptation of their 1-4 year olds in equal joint physical custody.

Malin Bergström, Anna Sarkadi, Anders Hjern, Emma Fransson,

Joint physical custody (JPC) refers to a practice where children with separated parents share their time between the parents' respective homes. Studies on parents' views of JPC for young children are scarce. The aim of this interview study was to explore parents' perceptions on how they experience and practice equally ... Read more >>

PLoS ONE (PloS one)
[2019, 14(4):e0214913]

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Characteristics of women with different perinatal depression trajectories.

Anna Wikman, Cathrine Axfors, Stavros I Iliadis, John Cox, Emma Fransson, Alkistis Skalkidou,

Maternal perinatal depression (PND), a common mental disorder with a prevalence of over 10%, is associated with long-term health risks for both mothers and offspring. This study aimed at describing characteristics related to background and lifestyle, pregnancy, delivery, and postpartum of different PND trajectories defined according to the onset of ... Read more >>

J. Neurosci. Res. (Journal of neuroscience research)
[2020, 98(7):1268-1282]

Cited: 1 time

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Inflammatory markers in women with postpartum depressive symptoms.

Emma Bränn, Emma Fransson, Richard A White, Fotios C Papadopoulos, Åsa Edvinsson, Masood Kamali-Moghaddam, Janet L Cunningham, Inger Sundström-Poromaa, Alkistis Skalkidou,

Postpartum depression (PPD) is a devastating disorder affecting not only more than 10% of all women giving birth, but also the baby, the family, and the society. Compiling evidence suggests the involvement of the immune system in the pathophysiology of major depression; yet, the immune response in perinatal depression is ... Read more >>

J. Neurosci. Res. (Journal of neuroscience research)
[2020, 98(7):1309-1321]

Cited: 2 times

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Children with two homes: Psychological problems in relation to living arrangements in Nordic 2- to 9-year-olds.

Malin Bergström, Emma Fransson, Michael B Wells, Lennart Köhler, Anders Hjern,

AIM:Joint physical custody, children spending equal time in each parents' respective home after a parental divorce, is particularly common in Nordic compared with other Western countries. Older children have been shown to fare well in this practice but for young children there are few existing studies. The aim of this ... Read more >>

Scand J Public Health (Scandinavian journal of public health)
[2019, 47(2):137-145]

Cited: 1 time

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Low levels of anti-secretory factor in placenta are associated with preterm birth and inflammation.

Anna M Gustafsson, Emma Fransson, Aurelija Dubicke, Anna K Hjelmstedt, Gunvor Ekman-Ordeberg, Sven-Arne Silfverdal, Stefan Lange, Eva Jennische, Kajsa Bohlin,

INTRODUCTION:Anti-secretory factor is a protein that regulates secretory and inflammatory processes and preterm birth is associated with inflammation. Therefore, our hypothesis was that anti-secretory factor might play a role in immune reactivity and homeostasis during pregnancy. MATERIAL AND METHODS:Following spontaneous onset of labor and preterm or term delivery, placenta biopsies ... Read more >>

Acta Obstet Gynecol Scand (Acta obstetricia et gynecologica Scandinavica)
[2018, 97(3):349-356]

Cited: 1 time

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Preschool children living in joint physical custody arrangements show less psychological symptoms than those living mostly or only with one parent.

Malin Bergström, Emma Fransson, Helena Fabian, Anders Hjern, Anna Sarkadi, Raziye Salari,

AIM:Joint physical custody (JPC), where children spend about equal time in both parent's homes after parental separation, is increasing. The suitability of this practice for preschool children, with a need for predictability and continuity, has been questioned. METHODS:In this cross-sectional study, we used data on 3656 Swedish children aged three ... Read more >>

Acta Paediatr. (Acta paediatrica (Oslo, Norway : 1992))
[2018, 107(2):294-300]

Cited: 2 times

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Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.

Emma Bränn, Fotios Papadopoulos, Emma Fransson, Richard White, Åsa Edvinsson, Charlotte Hellgren, Masood Kamali-Moghaddam, Adrian Boström, Helgi B Schiöth, Inger Sundström-Poromaa, Alkistis Skalkidou,

Recent studies indicate that the immune system adaptation during pregnancy could play a significant role in the pathophysiology of perinatal depression. The aim of this study was to investigate if inflammation markers in a late pregnancy plasma sample can predict the presence of depressive symptoms at eight weeks postpartum. Blood ... Read more >>

Psychoneuroendocrinology (Psychoneuroendocrinology)
[2017, 79:146-159]

Cited: 9 times

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The preterm cervix reveals a transcriptomic signature in the presence of premature prelabor rupture of membranes.

Sofia Makieva, Aurelija Dubicke, Sara F Rinaldi, Emma Fransson, Gunvor Ekman-Ordeberg, Jane E Norman,

BACKGROUND:Premature prelabor rupture of fetal membranes accounts for 30% of all premature births and is associated with detrimental long-term infant outcomes. Premature cervical remodeling, facilitated by matrix metalloproteinases, may trigger rupture at the zone of the fetal membranes overlying the cervix. The similarities and differences underlying cervical remodeling in premature ... Read more >>

Am. J. Obstet. Gynecol. (American journal of obstetrics and gynecology)
[2017, 216(6):602.e1-602.e21]

Cited: 2 times

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The Living Conditions of Children with Shared Residence - the Swedish Example.

Emma Fransson, Sara Brolin Låftman, Viveca Östberg, Anders Hjern, Malin Bergström,

Among children with separated parents, shared residence - i.e., joint physical custody where the child is sharing his or her time equally between two custodial parents' homes - is increasing in many Western countries and is particularly common in Sweden. The overall level of living among children in Sweden is ... Read more >>

Child Indic Res (Child indicators research)
[2018, 11(3):861-883]

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Psychological complaints among children in joint physical custody and other family types: Considering parental factors.

Emma Fransson, Jani Turunen, Anders Hjern, Viveca Östberg, Malin Bergström,

Increasing proportions of Scandinavian children and children in other Western countries live in joint physical custody, moving between parents' homes when parents live apart. Children and parents in non-intact families are at risk of worse mental health. The potential influence of parental ill-health on child well-being in the context of ... Read more >>

Scand J Public Health (Scandinavian journal of public health)
[2016, 44(2):177-183]

Cited: 4 times

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Fifty moves a year: is there an association between joint physical custody and psychosomatic problems in children?

Malin Bergström, Emma Fransson, Bitte Modin, Marie Berlin, Per A Gustafsson, Anders Hjern,

In many Western countries, an increasing number of children with separated parents have joint physical custody, that is, live equally much in their parent's respective homes. In Sweden, joint physical custody is particularly common and concerns between 30% and 40% of the children with separated parents. It has been hypothesised ... Read more >>

J Epidemiol Community Health (Journal of epidemiology and community health)
[2015, 69(8):769-774]

Cited: 9 times

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Mental health in Swedish children living in joint physical custody and their parents' life satisfaction: a cross-sectional study.

Malin Bergström, Emma Fransson, Anders Hjern, Lennart Köhler, Thomas Wallby,

This study compared the psychological symptoms of 129 children in joint physical custody with children in single care and nuclear families, using a nationally representative 2011 survey of 1,297 Swedish children aged between four and 18 years. The outcome measure was the Strengths and Difficulties Questionnaire (SDQ) and its association ... Read more >>

Scand J Psychol (Scandinavian journal of psychology)
[2014, 55(5):433-439]

Cited: 9 times

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Exploring salivary cortisol and recurrent pain in mid-adolescents living in two homes.

Emma Fransson, Lisa Folkesson, Malin Bergström, Viveca Östberg, Petra Lindfors,

BACKGROUND: Each year, around 50.000 children in Sweden experience a separation between their parents. Joint physical custody (JPC), where the child alternates homes between the parents for about equal amount of time, has become a common living arrangement after parental separation. Children in two homes could benefit from everyday contact ... Read more >>

BMC Psychol (BMC psychology)
[2014, 2(1):46]

Cited: 1 time

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Living in two homes-a Swedish national survey of wellbeing in 12 and 15 year olds with joint physical custody.

Malin Bergström, Bitte Modin, Emma Fransson, Luis Rajmil, Marie Berlin, Per A Gustafsson, Anders Hjern,

BACKGROUND: The practice of joint physical custody, where children spend equal time in each parent's home after they separate, is increasing in many countries. It is particularly common in Sweden, where this custody arrangement applies to 30 per cent of children with separated parents. The aim of this study was ... Read more >>

BMC Public Health (BMC public health)
[2013, 13:868]

Cited: 18 times

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Negative emotions and cytokines in maternal and cord serum at preterm birth.

Emma Fransson, Aurelija Dubicke, Birgitta Byström, Gunvor Ekman-Ordeberg, Anna Hjelmstedt, Mats Lekander,

PROBLEM: This study investigates whether affectivity differs between mothers delivering preterm and term and whether maternal and umbilical cord serum cytokines differ between these groups. Further, whether there are associations between mothers' emotions and maternal and cord cytokines at preterm and term birth. METHOD OF STUDY: Twenty-seven mothers delivering preterm ... Read more >>

Am. J. Reprod. Immunol. (American journal of reproductive immunology (New York, N.Y. : 1989))
[2012, 67(6):506-514]

Cited: 11 times

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Antenatal depressive symptoms and preterm birth: a prospective study of a Swedish national sample.

Emma Fransson, Annica Ortenstrand, Anna Hjelmstedt,

BACKGROUND: Preterm birth is the principal risk factor for neonatal morbidity and mortality. The objective of this study was to investigate the association between antenatal depressive symptoms and preterm birth. METHODS: The study included a national sample of 2,904 pregnant women who were recruited at their first booked visit to ... Read more >>

Birth (Birth (Berkeley, Calif.))
[2011, 38(1):10-16]

Cited: 23 times

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High-mobility group box protein 1 and its signalling receptors in human preterm and term cervix.

Aurelija Dubicke, Peter Andersson, Emma Fransson, Eva Andersson, Angelos Sioutas, Anders Malmström, Eva Sverremark-Ekström, Gunvor Ekman-Ordeberg,

The objective of this study was to identify possible changes in mRNA and protein expression of high-mobility group box protein 1 (HMGB1) and its suggested receptors - receptor for advanced glycation end-products (RAGE) and Toll-like receptor 2 (TLR2) and TLR4 - in human cervix during pregnancy, term and preterm labor. ... Read more >>

J. Reprod. Immunol. (Journal of reproductive immunology)
[2010, 84(1):86-94]

Cited: 19 times

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Pro-inflammatory and anti-inflammatory cytokines in human preterm and term cervical ripening.

Aurelija Dubicke, Emma Fransson, Gabriele Centini, Eva Andersson, Birgitta Byström, Anders Malmström, Felice Petraglia, Eva Sverremark-Ekström, Gunvor Ekman-Ordeberg,

Cervical ripening is necessary for successful delivery. Since cytokines are believed to be involved in this process, the aim of this study was to investigate possible changes in the mRNA and protein expression of pro-inflammatory cytokines (interleukin (IL)-1alpha, IL-1beta, IL-12, IL-18) and anti-inflammatory cytokines (IL-4, IL-10, IL-13) in the human ... Read more >>

J. Reprod. Immunol. (Journal of reproductive immunology)
[2010, 84(2):176-185]

Cited: 28 times

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