Full Text Journal Articles by
Author Emin Ozlu

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Correlation study between clinical classification and disability index in a holistic evaluation of acne severity and impact in Turkey.

Emin Ozlu, Ayse S Karadag, Berna Aksoy, Serap Gunes Bilgili, Muzeyyen Gonul, İbrahim H Yavuz, Engin Senel, Mualla Polat, Tugba O Akbulut, Deniz Aksu, Filiz Topaloglu, Burak Tekin, Wen C Chen,

BACKGROUND:Comparison between disease severity observed by inspectors and the disease burden assessed by patients is scanty in acne study. METHODS:In a multicenter prospective hospital-based study, modified Comprehensive Acne Severity Scale (mCASS) and Cardiff Acne Disability Index (CADI) were employed to grade disease severity and to determine the quality of life, ... Read more >>

G Ital Dermatol Venereol (Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia)
[2020, :]

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Introduction of a novel quantitative scoring system for acanthosis nigricans and its validation in a pilot study.

Ayse Serap Karadag, Tugba Kevser Uzuncakmak, Emin Ozlu, Mumtaz Takir, Remzi Karadag, Osman Kostek, Mehmet Simsek, Necmettin Akdeniz, Uwe Wollina, WenChieh Chen,

Inconsistent data exist regarding the diagnostic value of acanthosis nigricans (AN) or skin tags as clinical markers for obesity or diabetes. In an outpatient department-based prospective study, we designed a scoring for AN severity (SCANS) to evaluate AN and skin tags, their correlation with obesity or diabetes. Quantification of AN ... Read more >>

Dermatol Ther (Dermatologic therapy)
[2020, :e14450]

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Acne in pregnancy: A prospective multicenter, cross-sectional study of 295 patients in Turkey.

Ömer Kutlu, Ayşe Serap Karadağ, Emine Ünal, Kıymet Handan Kelekçi, Ayşegül Yalçınkaya İyidal, Filiz Topaloğlu Demir, Berna Aksoy, Emine Çölgeçen, Mustafa Tosun, Selma Emre, Aslı Tatlıparmak, Düriye Deniz Demirseren, Hatice Kaya Özden, Murat Öztürk, Emin Özlü, Wenchieh Chen,

BACKGROUND:There are only a few studies on acne in pregnancy. This study was aimed to investigate the demographic, clinical, and familial characteristics of acne in pregnancy, triggering factors including endocrine diseases, and association of these findings with acne in different trimesters of pregnancy. METHODS:Pregnant women aged 18 years and older with ... Read more >>

Int J Dermatol (International journal of dermatology)
[2020, 59(9):1098-1105]

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Effects of Different Doses of Systemic Isotretinoin on Eyes: A Histopathological and Immunohistochemical Study in Rats.

Remzi Karadag, Ayse Serap Karadag, Emin Ozlu, Serpil Oguztuzun, Gulcin Guler Simsek, Oktay Esmer, Sevda Onder, Serap Gunes Bilgili,

PURPOSE:To evaluate ocular side effects associated with systemic isotretinoin histopathologically. METHODS:In this multicenter study, a total of 15 male and 15 female rats were randomly divided into 3 equal groups according to the oral dose of isotretinoin they were administered: 0 mg/kg/d (group A), 7.5 mg/kg/d (group B), and 15 ... Read more >>

Cornea (Cornea)
[2020, 39(5):621-627]

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Nineteen-year retrospective evaluation of pemphigus in a single dermatology centre in Istanbul, Turkey.

Mukaddes Kavala, İlkin Zindancı, Zafer Turkoglu, Burce Can Kuru, Emin Ozlu, Mehmet Simsek,

Introduction:Pemphigus is an autoimmune intra-epidermal bullous disease of the skin and mucosae. Aim:To retrospectively evaluate the course, prognosis and clinical features of pemphigus. Material and methods:The files of 196 pemphigus patients admitted to our clinic between December 1995 and December 2014 were collected and analysed. Results:The male to female ratio ... Read more >>

Postepy Dermatol Alergol (Postepy dermatologii i alergologii)
[2020, 37(1):23-28]

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Alteration of tissue expression of human beta defensin-1 and human beta defensin-2 in psoriasis vulgaris following phototherapy.

Tugba Kevser Uzuncakmak, Ayse Serap Karadag, Seyma Ozkanli, Ozge Akbulak, Emin Ozlu, Necmettin Akdeniz, Serpil Oguztuzun,

We compared the expression profiles of antimicrobial peptides (AMPs) in psoriatic skin before and after narrow band ultraviolet B (nb-UVB) phototherapy and compared the levels to healthy controls. We studied 15 male and 12 female patients with psoriasis vulgaris, and 11 female and nine male control individuals. The patient group ... Read more >>

Biotech Histochem (Biotechnic & histochemistry : official publication of the Biological Stain Commission)
[2020, 95(4):243-248]

Cited: 1 time

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Morphea secondary to interferon beta1b injection: a case and review of the literature.

Emin Ozlu, Ayse Serap Karadag, Necmettin Akdeniz, Tugba Kevser Uzuncakmak, Ebru Zemheri, Seyma Ozkanli,

Interferon beta (IFNβ) is a drug used successfully in the treatment of multiple sclerosis (MS). Although IFNβ is a safe and well-tolerated drug, dermatological side effects are common. The most common dermatological adverse effect is a local reaction at the injection site. It may also cause inflammatory and immune-mediated dermatological ... Read more >>

Dermatol Online J (Dermatology online journal)
[2019, 25(4):]

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Effect of low-dose acitretin treatment on pituitary hormones in psoriasis vulgaris: A retrospective study.

Ayse Serap Karadag, Emin Ozlu, Osman Kostek, Serap Gunes Bilgili, Ragıp Balaharoglu, Derun Taner Ertugrul,

Background:It has been reported that retinoids may lead to hormonal alterations. Aim:In this retrospective study, we aimed to study the effect of acitretin on pituitary hormones in psoriasis patients. Methods:Out of 50 patients intended to be studied, blood samples of 43 patients could be tested before and after 3 months ... Read more >>

Indian J Dermatol Venereol Leprol (Indian journal of dermatology, venereology and leprology)
[2019, 85(3):300-304]

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Evaluation of platelet parameters and neutrophil/lymphocyte ratio during omalizumab treatment in patients with severe chronic spontaneous urticaria

Ragıp Ertaş, Kemal Özyurt, Çiğdem Karakükçü, Muhammet Reşat Akkuş, Emin Özlü, Atıl Avcı, Mustafa Atasoy,

Background/aim:Spontaneous wheals and/or angioedema lasting longer than six weeks are described as chronic spontaneous urticaria (CSU). Omalizumab is used for the treatment of antihistamine-resistant CSU. The neutrophil–lymphocyte ratio (NLR), platelet– lymphocyte ratio (PLR), mean platelet volume (MPV), ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2018, 48(6):1255-1262]

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Comparison of cutaneous manifestations in diabetic and nondiabetic obese patients: A prospective, controlled study.

Emin Ozlu, Tugba Kevser Uzuncakmak, Mumtaz Takır, Necmettin Akdeniz, Ayse Serap Karadag,

OBJECTIVE:Obesity is known to be a risk factor for many diseases including dermatological problems. Here, we aimed to determine the cutaneous manifestations in obese patients and the frequency of the accompanying dermatoses and to investigate the effect of diabetes mellitus in obese patients on cutaneous manifestations compared with the control ... Read more >>

North Clin Istanb (Northern clinics of Istanbul)
[2018, 5(2):114-119]

Cited: 2 times

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The rapid effect of pulsed dye laser on demodex density of facial skin.

Ragıp Ertaş, Ozan Yaman, M Reşat Akkuş, Emin Özlü, Atıl Avcı, Yılmaz Ulaş, Kemal Ozyurt, Mustafa Atasoy,

BACKGROUND:Recently, treatment with acaricides, which is aimed at reducing excessive proliferation of demodex mites, has gained popularity due to its providing a significant improvement in the symptoms of diseases, such as rosacea, seborrhoeic dermatitis, and perioral dermatitis. The effect of IPL on demodex mites was reported in skin biopsy specimens ... Read more >>

J Cosmet Laser Ther (Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology)
[2019, 21(3):123-126]

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Behçet Disease: New Developments in the Etiopathogenesis of an Old Silk Road Disease.

Emin Ozlu, Ayse Serap Karadag,

Behçet disease (BD) is a systemic inflammatory disorder that affects the skin, mucosa, eyes, joints, blood vessels, brain, and gastrointestinal tract. The etiopathogenesis of BD has not yet been fully elucidated, but disorganized immune responses against the stimuli of environmental triggering factors have been considered to play a major role ... Read more >>

Skinmed (Skinmed)
[2018, 16(3):176-181]

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Evaluation of ocular findings in patients with lichen planus.

Emin Ozlu, Kuddusi Teberik,

Introduction:Lichen planus (LP) is a chronic, inflammatory disease of unknown etiology. Aim:To evaluate the tear functions and the retinal and choroidal thickness (CT) in patients with LP. Material and methods:In total, 33 patients and 30 healthy controls were enrolled. All participants were evaluated using the Ocular Surface Disease Index (OSDI) ... Read more >>

Postepy Dermatol Alergol (Postepy dermatologii i alergologii)
[2019, 36(3):267-271]

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Plantar Fibromatosis in a Mentally Challenged Man Treated with Intralesional Corticosteroids.

Ayse Serap Karadag, Emin Ozlu, Ayse Bahar Ceyran, Mehmet Simsek, Tugba Kevser Uzuncakmak, Ilkin Zindancı, Necmettin Akdeniz,

A 21-year-old mentally challenged man presented with a fixed plaque lesion on the right foot, which had been present for 10 years. Dermatologic examination revealed an erythematous, painful, firm, fixed plaque-nodular lesion on the plantar aspect of the right foot (Figure 1A). Nothing of distinction was noted from his family ... Read more >>

Skinmed (Skinmed)
[2017, 15(6):480-482]

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Cutaneous manifestations of diabetes mellitus and the metabolic syndrome.

Ayse Serap Karadag, Emin Ozlu, Michael Joseph Lavery,

Metabolic diseases are commonly encountered in the Western world. Cutaneous manifestations are common in metabolic disorders, such as diabetes mellitus (DM) and the metabolic syndrome (MetS), and metabolic diseases may manifest with specific skin findings. MetS and DM share a common mechanism in their etiopathogenesis. As a result, the skin ... Read more >>

Clin. Dermatol. (Clinics in dermatology)
[2018, 36(1):89-93]

Cited: 4 times

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Evaluation of oxidative stress via protein expression of glutathione S-transferase and cytochrome p450 (CYP450) ısoenzymes in psoriasis vulgaris patients treated with methotrexate.

Ozge Akbulak, Ayse Serap Karadag, Necmettin Akdeniz, Seyma Ozkanli, Emin Ozlu, Ebru Zemheri, Serpil Oguztuzun,

Oxidative stress is the imbalance between oxidant-antioxidant systems and may play a major role in the psoriasis pathogenesis. Cytochrome (CYP) is a family of enzymes that are responsible for the metabolism of various endogenous and exogenous substances such as drug metabolism. Most importantly, the antioxidant system is the glutathione S-transferases ... Read more >>

Cutan Ocul Toxicol (Cutaneous and ocular toxicology)
[2018, 37(2):180-185]

Cited: 1 time

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Skin findings in autoimmune and nonautoimmune thyroid disease with respect to thyroid functional status and healthy controls.

Mümtaz Takir, Emin Özlü, Osman Köstek, Zafer Türkoğlu, Hasan Hüseyin Mutlu, Tuğba Kevser Uzunçakmak, Necmettin Akdeniz, Ayşe Serap Karadağ,

BACKGROUND/AIM:Thyroid disorders are associated with a wide variety of skin disorders that respond to treatment of hormone imbalance in most cases and thus are of vital importance to dermatologists. This study aimed to evaluate skin findings associated with autoimmune and nonautoimmune thyroid disease with respect to thyroid functional status and ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2017, 47(3):764-770]

Cited: 0 times

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Case Report: Lupoid cutaneous leishmaniasis mimicking verruca plana

Emin Ozlu, Aysegul Baykan, Ozan Yaman, Ragıp Ertas, Mustafa Atasoy, Kemal Ozyurt, Abdullah Turasan, Nazan Taslıdere,

Cutaneous leishmaniasis (CL) is an infectious disease caused by various species of leishmania protozoan parasites. Lupoid CL is a rare form of CL that has a stunning similarity to other granulomatous cutaneous conditions of infectious or inflammatory origin. Verruca plana, also known as a “flat wart”, is a benign proliferation ... Read more >>

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Increased IgE levels are linked to faster relapse in patients with omalizumab-discontinued chronic spontaneous urticaria.

Ragip Ertas, Kemal Ozyurt, Emin Ozlu, Yilmaz Ulas, Atil Avci, Mustafa Atasoy, Tomasz Hawro, Marcus Maurer,

J. Allergy Clin. Immunol. (The Journal of allergy and clinical immunology)
[2017, 140(6):1749-1751]

Cited: 7 times

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Giant neglected Bowen's disease lesion treated successfully with topical 5-fluorouracil.

Emin Ozlu, Ragıp Ertas, Kemal Ozyurt, Yucel Tekin, Mustafa Atasoy,

North Clin Istanb (Northern clinics of Istanbul)
[2017, 4(1):77]

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Case Report: Lupoid cutaneous leishmaniasis mimicking verruca plana.

Emin Ozlu, Aysegul Baykan, Ozan Yaman, Ragıp Ertas, Mustafa Atasoy, Kemal Ozyurt, Abdullah Turasan, Nazan Taslıdere,

Cutaneous leishmaniasis (CL) is an infectious disease caused by various species of leishmania protozoan parasites. Lupoid CL is a rare form of CL that has a stunning similarity to other granulomatous cutaneous conditions of infectious or inflammatory origin. Verruca plana, also known as a "flat wart", is a benign proliferation ... Read more >>

F1000Res (F1000Research)
[2017, 6:947]

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Case Report: Nicolau syndrome due to etofenamate injection

Emin Ozlu, Aysegul Baykan, Ragıp Ertas, Yılmaz Ulas, Kemal Ozyurt, Atıl Avcı, Halit Baykan,

Nicolau syndrome, also known as embolia cutis medicomentosa, is a rare complication characterized by tissue necrosis that occurs after injection of drugs. The exact pathogenesis is uncertain, but there are several hypotheses, including direct damage to the end artery and cytotoxic effects of the drug. Severe pain in the immediate ... Read more >>

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Case Report: Nicolau syndrome due to etofenamate injection.

Emin Ozlu, Aysegul Baykan, Ragıp Ertas, Yılmaz Ulas, Kemal Ozyurt, Atıl Avcı, Halit Baykan,

Nicolau syndrome, also known as embolia cutis medicomentosa, is a rare complication characterized by tissue necrosis that occurs after injection of drugs. The exact pathogenesis is uncertain, but there are several hypotheses, including direct damage to the end artery and cytotoxic effects of the drug. Severe pain in the immediate ... Read more >>

F1000Res (F1000Research)
[2017, 6:867]

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The investigation of antimicrobial peptides expression and its related interaction with methotrexate treatment in patients with psoriasis vulgaris.

Emin Ozlu, Ayse Serap Karadag, Seyma Ozkanli, Serpil Oguztuzun, Ozge Akbulak, Tugba Kevser Uzuncakmak, Serkan Demirkan, Necmettin Akdeniz,

Psoriasis is a chronic, inflammatory and immune-mediated disease. Recently, the role of antimicrobial peptides (AMPs) such as human beta defensins (hBDs) in the pathogenesis of psoriasis has been investigated. We aimed to evaluate the expression profiles of hBD-1 and hBD-2 in psoriatic skin before and after methotrexate (MTX) therapy and ... Read more >>

Cutan Ocul Toxicol (Cutaneous and ocular toxicology)
[2017, 36(4):321-326]

Cited: 1 time

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Effective treatment of Fox-Fordyce disease with pulsed dye laser.

Tugba Kevser Uzuncakmak, Ayse Serap Karadag, Emin Ozlu, Necmettin Akdeniz, Bengu Cobanoglu Simsek,

Photodermatol Photoimmunol Photomed (Photodermatology, photoimmunology & photomedicine)
[2016, 32(5-6):311-313]

Cited: 1 time

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