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Author Emilie Belley Cote

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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1063-e1143]

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Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):1974-1982]

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New-onset atrial fibrillation in the medical intensive care unit: Catch me if you can.

Maria E Vadakken, Emilie P Belley-Cote, William F McIntyre,

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2021, :]

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Efficacy and safety of low intensity vitamin K antagonists in Western and East-Asian patients with left-sided mechanical heart valves.

Arjun K Pandey, Ke Xu, Li Zhang, Saurabh Gupta, John Eikelboom, Renato D Lopes, Mark Crowther, Emilie P Belley-Côté, Richard P Whitlock,

The optimal INR target in patients with mechanical heart valves is unclear. Higher INR targets are often used in Western compared with East Asian countries. The objective of this systematic review and meta-analysis was to summarize the evidence for the efficacy and safety of lower versus higher INR targets in ... Read more >>

J Thromb Thrombolysis (Journal of thrombosis and thrombolysis)
[2021, :]

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Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Intensive Care Med (Intensive care medicine)
[2021, :]

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Post-discharge after surgery Virtual Care with Remote Automated Monitoring-1 (PVC-RAM-1) technology versus standard care: randomised controlled trial.

Michael H McGillion, Joel Parlow, Flavia K Borges, Maura Marcucci, Michael Jacka, Anthony Adili, Manoj M Lalu, Carley Ouellette, Marissa Bird, Sandra Ofori, Pavel S Roshanov, Ameen Patel, Homer Yang, Susan O'Leary, Vikas Tandon, Gavin M Hamilton, Marko Mrkobrada, David Conen, Valerie Harvey, Jennifer Lounsbury, Rajibul Mian, Shrikant I Bangdiwala, Ramiro Arellano, Ted Scott, Gordon H Guyatt, Peggy Gao, Michelle Graham, Rahima Nenshi, Alan J Forster, Mahesh Nagappa, Kelsea Levesque, Kristen Marosi, Sultan Chaudhry, Shariq Haider, Lesly Deuchar, Brandi LeBlanc, Colin J L McCartney, Emil H Schemitsch, Jessica Vincent, Shirley M Pettit, Deborah DuMerton, Angela Djuric Paulin, Marko Simunovic, David C Williams, Samantha Halman, John Harlock, Ralph M Meyer, Dylan A Taylor, Harsha Shanthanna, Christopher M Schlachta, Neil Parry, David R Pichora, Haroon Yousuf, Elizabeth Peter, Andre Lamy, Jeremy Petch, Husein Moloo, Herman Sehmbi, Melissa Waggott, Jessica Shelley, Emilie P Belley-Cote, P J Devereaux, ,

<h4>Objective</h4>To determine if virtual care with remote automated monitoring (RAM) technology versus standard care increases days alive at home among adults discharged after non-elective surgery during the covid-19 pandemic.<h4>Design</h4>Multicentre randomised controlled trial.<h4>Setting</h4>8 acute care hospitals in Canada.<h4>Participants</h4>905 adults (≥40 years) who resided in areas with mobile phone coverage and were ... Read more >>

BMJ (BMJ (Clinical research ed.))
[2021, 374:n2209]

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Ross for Valve replacement In AduLts (REVIVAL) pilot trial: rationale and design of a randomised controlled trial.

Richard Whitlock, Emilie Belley-Cote, Filip Rega, Michael W A Chu, Graham R McClure, Hanna Hronyecz, Peter Verbrugghe, P J Devereaux, Shrikant Bangdiwala, John Eikelboom, Katheryn Brady, Ravil Sharifulin, Alexander Bogachev-Prokophiev, Serban Stoica,

<h4>Introduction</h4>In non-elderly adults, aortic valve replacement (AVR) with conventional prostheses yield poor long-term outcomes. Recent publications suggest a benefit of the Ross procedure over conventional AVR and highlight the need for high-quality randomised controlled trial (RCTs) on the optimal AVR. We have initiated a pilot trial assess two feasibility criteria ... Read more >>

BMJ Open (BMJ open)
[2021, 11(9):e046198]

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Outcomes of sutureless aortic valve replacement versus conventional aortic valve replacement and transcatheter aortic valve replacement, updated systematic review, and meta-analysis.

Kevin S Kim, Ahmad Makhdoum, Alex Koziarz, Saurabh Gupta, Ali Alsagheir, Arjun Pandey, Seleman Reza, Kevin Um, Kevin Teoh, Waleed Alhazzani, André Lamy, Bobby Yanagawa, Emilie P Belley-Côté, Richard P Whitlock,

<h4>Background</h4>Sutureless aortic valve replacement (SuAVR) is an alternative to surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR). This study compares the effectiveness of SuAVR to SAVR and TAVR.<h4>Methods</h4>We searched MEDLINE and EMBASE from inception to July 2021 for studies evaluating SuAVR, SAVR, and TAVR in adults with ... Read more >>

J Card Surg (Journal of cardiac surgery)
[2021, :]

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Pulmonary artery catheterization in patients with cardiogenic shock: a systematic review and meta-analysis.

Justin Y Chow, Maria E Vadakken, Richard P Whitlock, Alex Koziarz, Craig Ainsworth, Faizan Amin, William F McIntyre, Catherine Demers, Emilie P Belley-Côté,

<h4>Purpose</h4>Cardiogenic shock carries high morbidity and mortality. The purpose of this review was to determine the safety and efficacy of pulmonary artery catheterization (PAC) in adult patients hospitalized with cardiogenic shock.<h4>Source</h4>We performed a systematic review and meta-analysis of observational studies and randomized controlled trials comparing PAC vs no PAC in ... Read more >>

Can J Anaesth (Canadian journal of anaesthesia = Journal canadien d'anesthesie)
[2021, 68(11):1611-1629]

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Optimal VAsopressor TitraTION in patients 65 years and older (OVATION-65): protocol and statistical analysis plan for a randomised clinical trial.

Marie-Hélène Masse, Marie-Claude Battista, Mary Elizabeth Wilcox, Ruxandra Pinto, Nicole Marinoff, Frédérick D'Aragon, Charles St-Arnaud, Michael Mayette, Marc-André Leclair, Hector Quiroz Martinez, Brian Grondin-Beaudoin, Yannick Poulin, Élaine Carbonneau, Andrew J E Seely, Irene Watpool, Rebecca Porteous, Michaël Chassé, Martine Lebrasseur, François Lauzier, Alexis F Turgeon, David Bellemare, Sangeeta Mehta, Emmanuel Charbonney, Émilie Belley-Côté, Édouard Botton, Dian Cohen, François Lamontagne, Neill K J Adhikari, , ,

<h4>Introduction</h4>Vasodilatory hypotension is common among intensive care unit (ICU) patients; vasopressors are considered standard of care. However, optimal mean arterial pressure (MAP) targets for vasopressor titration are unknown. The objective of the Optimal VAsopressor TitraTION in patients 65 years and older (OVATION-65) trial is to ascertain the effect of permissive ... Read more >>

BMJ Open (BMJ open)
[2020, 10(11):e037947]

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COVID-19 and AF: What About the Long Game?

Maria E Vadakken, Emilie P Belley-Cote, William F McIntyre,

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, 7(9):1196-1197]

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Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke. Reply.

Emilie P Belley-Cote, Stuart J Connolly, Richard P Whitlock,

N Engl J Med (The New England journal of medicine)
[2021, 385(11):1054-1055]

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Sodium-Glucose Co-Transporter Inhibitors and Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Arjun K Pandey, Iva Okaj, Hargun Kaur, Emilie P Belley-Cote, Jia Wang, Alireza Oraii, Alexander P Benz, Linda S B Johnson, Jack Young, Jorge A Wong, Subodh Verma, David Conen, Hertzel Gerstein, Jeff S Healey, William F McIntyre,

Background Sodium-glucose co-transporter (SGLT) inhibitors reduce cardiovascular outcomes including mortality in several populations; however, their effect on atrial fibrillation/flutter (AF) remains unclear. Our objective was to determine whether SGLT inhibitors reduce AF and whether a history of AF modifies the effect of SGLT inhibitors on the composite of heart failure ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2021, 10(17):e022222]

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Single-dose oral anti-arrhythmic drugs for cardioversion of recent-onset atrial fibrillation: a systematic review and network meta-analysis of randomized controlled trials.

Omar A Ibrahim, Emilie P Belley-Côté, Kevin J Um, Adrian Baranchuk, Alexander P Benz, Shreyash Dalmia, Chang N Wang, Waleed Alhazzani, David Conen, P J Devereaux, Richard P Whitlock, Jeff S Healey, William F McIntyre,

<h4>Aims</h4>Single oral dose anti-arrhythmic drugs (AADs) are used to cardiovert recent-onset atrial fibrillation (AF); however, the optimal agent is uncertain.<h4>Methods</h4>We performed a systematic review and network meta-analysis of randomized trials testing single oral dose AADs vs. any comparator to cardiovert AF <7 days duration. We searched MEDLINE, Embase, and CENTRAL to ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2021, 23(8):1200-1210]

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Retrograde autologous priming in cardiac surgery: a systematic review and meta-analysis.

Saurabh Gupta, Charlotte McEwen, Ameen Basha, Puru Panchal, Adam Eqbal, Nicole Wu, Emilie P Belley-Cote, Richard Whitlock,

<h4>Objectives</h4>Guidelines recommend retrograde autologous priming (RAP) of the cardiopulmonary bypass circuit. However, the efficacy and safety of RAP is not well-established. We performed a systematic review and meta-analysis to determine the effects of RAP on transfusion requirements, morbidity and mortality.<h4>Methods</h4>We searched Cochrane Central Register of Controlled Trials, Medline, ScienceDirect, Cumulative ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2021, :]

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Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial.

Jennie Johnstone, Maureen Meade, François Lauzier, John Marshall, Erick Duan, Joanna Dionne, Yaseen M Arabi, Diane Heels-Ansdell, Lehana Thabane, Daphnee Lamarche, Michael Surette, Nicole Zytaruk, Sangeeta Mehta, Peter Dodek, Lauralyn McIntyre, Shane English, Bram Rochwerg, Tim Karachi, William Henderson, Gordon Wood, Daniel Ovakim, Margaret Herridge, John Granton, M Elizabeth Wilcox, Alberto Goffi, Henry T Stelfox, Daniel Niven, John Muscedere, François Lamontagne, Frédérick D'Aragon, Charles St-Arnaud, Ian Ball, Dave Nagpal, Martin Girard, Pierre Aslanian, Emmanuel Charbonney, David Williamson, Wendy Sligl, Jan Friedrich, Neill K Adhikari, François Marquis, Patrick Archambault, Kosar Khwaja, Arnold Kristof, James Kutsogiannis, Ryan Zarychanski, Bojan Paunovic, Brenda Reeve, François Lellouche, Paul Hosek, Jennifer Tsang, Alexandra Binnie, Sébastien Trop, Osama Loubani, Richard Hall, Robert Cirone, Steve Reynolds, Paul Lysecki, Eyal Golan, Rodrigo Cartin-Ceba, Robert Taylor, Deborah Cook, ,

<h4>Importance</h4>Growing interest in microbial dysbiosis during critical illness has raised questions about the therapeutic potential of microbiome modification with probiotics. Prior randomized trials in this population suggest that probiotics reduce infection, particularly ventilator-associated pneumonia (VAP), although probiotic-associated infections have also been reported.<h4>Objective</h4>To evaluate the effect of Lactobacillus rhamnosus GG on ... Read more >>

JAMA (JAMA)
[2021, 326(11):1024-1033]

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Standardized Assessment of Global activities in the Elderly scale in adult cardiac surgery patients.

Jessica Spence, Jackie Bosch, Edward Chongsi, Shun Fu Lee, Lehana Thabane, Pablo Mendoza, Emilie Belley-Côté, Richard Whitlock, Kate Brady, William F McIntyre, Andre Lamy, P J Devereaux,

<h4>Background</h4>Different instruments have been used to assess ability to perform everyday functional activities, such as activities of daily living (ADL) and instrumental activities of daily living (IADL). No measures of functional activity have been validated in cardiac surgery. We assessed the reliability and validity of the Standardized Assessment of Global ... Read more >>

Br J Anaesth (British journal of anaesthesia)
[2021, 127(4):539-546]

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Oral anticoagulation for patients with atrial fibrillation in the ED: RE-LY AF registry analysis.

Pablo A Mendoza, William F McIntyre, Emilie P Belley-Côté, Jia Wang, Ratika Parkash, Clare L Atzema, Alexander P Benz, Jonas Oldgren, Richard P Whitlock, Jeff S Healey, ,

Oral anticoagulation (OAC) reduces stroke risk in patients with atrial fibrillation (AF). We sought to determine predictors of OAC initiation in AF patients presenting to the emergency department (ED). Secondary analysis of the RE-LY AF registry which enrolled individuals from 47 countries between 2007 and 2011 who presented to an ... Read more >>

J Thromb Thrombolysis (Journal of thrombosis and thrombolysis)
[2021, :]

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The effects of dietary nitrate supplementation on endurance exercise performance and cardiorespiratory measures in healthy adults: a systematic review and meta-analysis.

Chloe Gao, Saurabh Gupta, Taranah Adli, Winston Hou, Reid Coolsaet, Abigail Hayes, Kevin Kim, Arjun Pandey, Jacob Gordon, Gurneet Chahil, Emilie P Belley-Cote, Richard P Whitlock,

<h4>Background</h4>Nitrate supplementation is thought to improve performance in endurance sports.<h4>Objective</h4>To meta-analyze studies evaluating the effect of nitrate supplementation on endurance sports performance among adults.<h4>Data sources</h4>We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, Web of Science and CINAHL without language restrictions.<h4>Methods</h4>We included studies that: 1) compared nitrate ... Read more >>

J Int Soc Sports Nutr (Journal of the International Society of Sports Nutrition)
[2021, 18(1):55]

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Patients with Atrial Fibrillation Undergoing Cardiac Surgery: No Left Atrial Appendage Shall Remain Untouched

Richard P Whitlock, Emilie P Belley-Cote,

The Left Atrial Appendage Occlusion Study III randomized 4,811 patients with atrial fibrillation and a CHA<sub>2</sub>DS<sub>2</sub>VASc score ≥2 undergoing cardiac surgery to surgical left atrial appendage occlusion or no occlusion. At a mean follow-up of 3.8 years, stroke or systemic embolism was reduced by 33% in the occlusion group with ... Read more >>

Innovations (Phila) (Innovations (Philadelphia, Pa.))
[2021, 16(4):301-302]

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Comparing Renal Replacement Therapy Modalities in Critically Ill Patients With Acute Kidney Injury: A Systematic Review and Network Meta-Analysis.

Zhikang Ye, Ying Wang, Long Ge, Gordon H Guyatt, David Collister, Waleed Alhazzani, Sean M Bagshaw, Emilie P Belley-Cote, Fang Fang, Liangying Hou, Philipp Kolb, Francois Lamontagne, Simon Oczkowski, Lonnie Pyne, Christian Rabbat, Matt Scaum, Borna Tadayon Najafabadi, Wimonchat Tangamornsuksan, Ron Wald, Qi Wang, Michael Walsh, Liang Yao, Linan Zeng, Abdullah Mohammed Algarni, Rachel J Couban, Paul Elias Alexander, Bram Rochwerg,

<h4>Objectives</h4>To compare different modalities of renal replacement therapy in critically ill adults with acute kidney injury.<h4>Data sources</h4>We searched Medline, PubMed, Embase, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov from inception to 25 May, 2020. We included randomized controlled trials comparing the efficacy and safety of different renal replacement therapy ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(5):e0399]

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Prevalence of Left Atrial Thrombus in Anticoagulated Patients With Atrial Fibrillation.

Antony Lurie, Jia Wang, Kyra J Hinnegan, William F McIntyre, Emilie P Belley-Côté, Guy Amit, Jeff S Healey, Stuart J Connolly, Jorge A Wong,

<h4>Background</h4>The prevalence of left atrial (LA) thrombus in patients with atrial fibrillation (AF) or atrial flutter (AFL) on guideline-directed anticoagulation is not well known, yet this may inform transesophageal echocardiogram (TEE) use before cardioversion or catheter ablation.<h4>Objectives</h4>The purpose of this study was to quantify LA thrombus prevalence among patients with ... Read more >>

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2021, 77(23):2875-2886]

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We need high quality evidence regarding the Ross operation.

Rachel Eikelboom, Emilie P Belley-Côté, Richard P Whitlock,

Ann Thorac Surg (The Annals of thoracic surgery)
[2021, :]

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Antemortem Heparin in Organ Donation after Circulatory Death Determination (DCDD): A Systematic Review of the Literature.

Kimia Honarmand, Fayez Alshamsi, Farid Foroutan, Bram Rochwerg, Emilie Belley-Cote, Graham Mclure, Frederick D'Aragon, Ian M Ball, Alp Sener, Markus Selzner, Gordon Guyatt, Maureen O Meade,

Donation after circulatory death determination (DCDD) frequently involves antemortem heparin administration to mitigate peri-arrest microvascular thrombosis. We systematically reviewed the literature to: (1) describe heparin administration practices, and (2) explore the effects on transplant outcomes. We searched MEDLINE and EMBASE for studies reporting DCDD heparin practices including use, dosage, and ... Read more >>

Transplantation (Transplantation)
[2021, :]

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Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke.

Richard P Whitlock, Emilie P Belley-Cote, Domenico Paparella, Jeff S Healey, Katheryn Brady, Mukul Sharma, Wilko Reents, Petr Budera, Andony J Baddour, Petr Fila, P J Devereaux, Alexander Bogachev-Prokophiev, Andreas Boening, Kevin H T Teoh, Georgios I Tagarakis, Mark S Slaughter, Alistair G Royse, Shay McGuinness, Marco Alings, Prakash P Punjabi, C David Mazer, Richard J Folkeringa, Andrea Colli, Álvaro Avezum, Juliet Nakamya, Kumar Balasubramanian, Jessica Vincent, Pierre Voisine, Andre Lamy, Salim Yusuf, Stuart J Connolly, ,

<h4>Background</h4>Surgical occlusion of the left atrial appendage has been hypothesized to prevent ischemic stroke in patients with atrial fibrillation, but this has not been proved. The procedure can be performed during cardiac surgery undertaken for other reasons.<h4>Methods</h4>We conducted a multicenter, randomized trial involving participants with atrial fibrillation and a CHA<sub>2</sub>DS<sub>2</sub>-VASc ... Read more >>

N Engl J Med (The New England journal of medicine)
[2021, 384(22):2081-2091]

Cited: 7 times

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