Full Text Journal Articles by
Author Emile Latour

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Missing data in primary care research: importance, implications and approaches.

Miguel Marino, Jennifer Lucas, Emile Latour, John D Heintzman,

Fam Pract (Family practice)
[2021, :]

Cited: 0 times

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Treatment of pyoderma gangrenosum: A multicenter survey-based study assessing satisfaction and quality of life.

Misty M Hobbs, Rebecca Byler, Emile Latour, Lauren Bonomo, Kerry Hennessy, Carla N Cruz-Diaz, Michi M Shinohara, Lucia Seminario-Vidal, Kanade Shinkai, Alex G Ortega-Loayza,

Pyoderma gangrenosum (PG) lacks consensus regarding treatment, and no prior studies assess treatment satisfaction in PG. The objective of this study was to determine patient-reported satisfaction in the treatment of PG, and associations with satisfaction. Methodology was a multicenter cross-sectional survey for patients who received systemic medication(s) to treat PG. ... Read more >>

Dermatol Ther (Dermatologic therapy)
[2021, :e14736]

Cited: 0 times

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Predictors of Virologic Failure Among a Cohort of HIV-infected Children in Southern Ethiopia.

Birkneh Tilahun Tadesse, Byron Alexander Foster, Emile Latour, Jeong Youn Lim, Degu Jerene, Andrea Ruff, Eleni Aklillu,

<h4>Background</h4>Optimal care for children with HIV infection includes timely assessment of treatment failure. Using HIV viral load to define treatment failure remains a challenge in resource-limited settings.<h4>Methods</h4>Children with HIV infection who were already on or starting first-line antiretroviral therapy were enrolled and followed over time. We examined clinical and immunologic ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(1):60-65]

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A Survey of American College of Mohs Surgery Videography Practices.

Erika L Hagstrom, Dylan Haynes, Emile Latour, Justin J Leitenberger,

Dermatol Surg (Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.])
[2020, :]

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Phase II Study of Ipilimumab in Men With Metastatic Prostate Cancer With an Incomplete Response to Androgen Deprivation Therapy.

Julie N Graff, Mark N Stein, Rishi Surana, Luai Al Rabadi, Eric Liu, Lawrence Fong, Shawna Bailey, Emile Latour, Timothy A Newby, Amy E Moran, Tomasz M Beer,

<b>Background:</b> Phase 3 studies of immune checkpoint inhibitors have not shown a survival benefit in prostate cancer, but some patients have a profound anticancer response. <b>Patients and Methods:</b> We evaluated the efficacy of the CTLA-4 targeted agent, ipilimumab, in metastatic prostate cancer patients who had an incomplete biochemical response to ... Read more >>

Front Oncol (Frontiers in oncology)
[2020, 10:1381]

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Invasive Melanoma and Melanoma in Situ Treated With Modified Mohs Micrographic Surgery With En Face Permanent Sectioning: A 10-Year Retrospective Review.

Michael Heath, Meghan Woody, Justin Leitenberger, Emile Latour, Anna Bar,

<h4>Background</h4>Successful surgical treatment of cutaneous melanoma is dependent on margin control.<h4>Objective</h4>To determine efficacy of modified Mohs micrographic surgery (mMMS) with en face permanent margins in management of invasive melanoma (IM) and melanoma in situ (MIS).<h4>Methods</h4>A retrospective cohort study evaluating local recurrence, 5-year recurrence-free survival, and 5-year melanoma-specific survival. Overall, 657 ... Read more >>

Dermatol Surg (Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.])
[2020, 46(8):1004-1013]

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A phase II single-arm study of pembrolizumab with enzalutamide in men with metastatic castration-resistant prostate cancer progressing on enzalutamide alone.

Julie N Graff, Tomasz M Beer, Joshi J Alumkal, Rachel E Slottke, William L Redmond, George V Thomas, Reid F Thompson, Mary A Wood, Yoshinobu Koguchi, Yiyi Chen, Emile Latour, Raymond C Bergan, Charles G Drake, Amy E Moran,

BACKGROUND:Checkpoint inhibitors can induce profound anticancer responses, but programmed cell death protein-1 (PD-1) inhibition monotherapy has shown minimal activity in prostate cancer. A published report showed that men with prostate cancer who were resistant to the second-generation androgen receptor inhibitor enzalutamide had increased programmed death-ligand 1 (PD-L1) expression on circulating ... Read more >>

J Immunother Cancer (Journal for immunotherapy of cancer)
[2020, 8(2):]

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Comparison of Three Diagnostic Frameworks for Pyoderma Gangrenosum.

Carter Haag, Trevor Hansen, Tamar Hajar, Emile Latour, Jesse Keller, Kanade Shinkai, Alex G Ortega-Loayza,

Pyoderma gangrenosum (PG) is an inflammatory condition characterized by chronic cutaneous ulcerations. There are three proposed PG diagnostic frameworks (Su, PARACELSUS, Delphi); however, they lack consensus, and their performance has not yet been validated in a well-defined cohort of patients with PG. In this cross-sectional retrospective cohort study, we sought ... Read more >>

J Invest Dermatol (The Journal of investigative dermatology)
[2021, 141(1):59-63]

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Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance.

Joshi J Alumkal, Duanchen Sun, Eric Lu, Tomasz M Beer, George V Thomas, Emile Latour, Rahul Aggarwal, Jeremy Cetnar, Charles J Ryan, Shaadi Tabatabaei, Shawna Bailey, Claire B Turina, David A Quigley, Xiangnan Guan, Adam Foye, Jack F Youngren, Joshua Urrutia, Jiaoti Huang, Alana S Weinstein, Verena Friedl, Matthew Rettig, Robert E Reiter, Daniel E Spratt, Martin Gleave, Christopher P Evans, Joshua M Stuart, Yiyi Chen, Felix Y Feng, Eric J Small, Owen N Witte, Zheng Xia,

The androgen receptor (AR) antagonist enzalutamide is one of the principal treatments for men with castration-resistant prostate cancer (CRPC). However, not all patients respond, and resistance mechanisms are largely unknown. We hypothesized that genomic and transcriptional features from metastatic CRPC biopsies prior to treatment would be predictive of de novo ... Read more >>

Proc Natl Acad Sci U S A (Proceedings of the National Academy of Sciences of the United States of America)
[2020, 117(22):12315-12323]

Cited: 1 time

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Evaluation of the Effectiveness and Tolerability of Mycophenolate Mofetil and Mycophenolic Acid for the Treatment of Morphea.

Megan Arthur, Nicole M Fett, Emile Latour, Heidi Jacobe, Elaine Kunzler, Stephanie Florez-Pollack, Jacob Houser, Shivani Sharma, Smriti Prasad, Alisa Femia, Marleigh J Stern, Lisa K Pappas-Taffer, Rebecca Gaffney, Anthony P Fernandez, Daniel Knabel, Adela Rambi Cardones, Nicole Leung, Anne Laumann, Jeong Min Yu, Jeffrey Zhao, Ruth Ann Vleugels, Elizabeth Tkachenko, Kelly Lo,

<h4>Importance</h4>First-line systemic therapy for morphea includes methotrexate with or without systemic corticosteroids. When this regimen is ineffective, not tolerated, or contraindicated, a trial of mycophenolate mofetil (MMF) or mycophenolic acid (MPA)-referred to herein as mycophenolate-is recommended; however, evidence to support this recommendation remains weak.<h4>Objective</h4>To evaluate the effectiveness and tolerability of ... Read more >>

JAMA Dermatol (JAMA dermatology)
[2020, 156(5):521-528]

Cited: 0 times

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Using a Multimedia Tool for Informed Consent in Mohs Surgery: A Randomized Trial Measuring Effects on Patient Anxiety, Knowledge, and Satisfaction.

Macey Delcambre, Dylan Haynes, Tamar Hajar, Spring Golden, Anna Bar, Emile Latour, Justin J Leitenberger,

BACKGROUND:Multimedia educational materials have been found to improve aspects of informed consent, although data in the context of Mohs micrographic surgery (MMS) is limited. OBJECTIVE:To assess whether a preoperative educational video decreases anxiety, increases comprehension, and improves overall satisfaction for patients undergoing same-day office consultation and MMS. MATERIALS AND METHODS:This ... Read more >>

Dermatol Surg (Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.])
[2020, 46(5):591-598]

Cited: 0 times

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Characteristics of patients with celiac disease and connective tissue disease overlap.

Bridget E Shields, Emile Latour, Nicole M Fett,

Int J Dermatol (International journal of dermatology)
[2020, 59(8):e309-e312]

Cited: 0 times

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Inpatient teledermatology: Diagnostic and therapeutic concordance among a hospitalist, dermatologist, and teledermatologist using store-and-forward teledermatology.

Jesse J Keller, Jacob P Johnson, Emile Latour,

BACKGROUND:Inpatient dermatology has been shown to improve patient outcomes at a reduced cost. Few hospitals have dermatologists available. Teledermatology may allow dermatologists to assess hospitalized patients remotely. OBJECTIVE:To examine the diagnostic concordance between a hospitalist, dermatologist, and teledermatologist using store-and-forward teledermatology. METHODS:For 100 consecutive patients requiring inpatient dermatology consultation, a survey ... Read more >>

J Am Acad Dermatol (Journal of the American Academy of Dermatology)
[2020, 82(5):1262-1267]

Cited: 3 times

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Perioperative management of pyoderma gangrenosum.

Carter K Haag, Lindsay Bacik, Emile Latour, Daniel C Morse, Nicole M Fett, Alex G Ortega-Loayza,

Pyoderma gangrenosum (PG) classically presents with an acute inflammatory stage, characterized by rapid evolution of painful ulcerations. The pathergy associated with PG lesions complicates disease management. Although PG is commonly treated with immunosuppression, some patients have refractory noninflammatory ulcers. In this subpopulation, there are case reports of successful surgical treatment. However, ... Read more >>

J Am Acad Dermatol (Journal of the American Academy of Dermatology)
[2020, 83(2):369-374]

Cited: 0 times

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The utility and challenges of histopathologic evaluation in the diagnosis of nonmalignant skin ulcers.

Phoebe Hammer, Emile Latour, Mary C Bohnett, Fatima McKenzie, Veselina B Korcheva, Stephanie Mengden, Kevin P White, Alex G Ortega-Loayza,

Histopathologic evaluation of cutaneous ulcers is indicated when the clinical diagnosis is unclear or when ulcers have not responded to standard of care. Many nonmalignant skin ulcers lack specific histologic findings on biopsy and pose a diagnostic challenge. While the usefulness of skin biopsies to diagnose underlying malignancy in ulcerated ... Read more >>

Wound Repair Regen (Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society)
[2020, 28(2):219-223]

Cited: 0 times

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Ipilimumab-induced hypophysitis, a single academic center experience.

Travis Snyders, Daniel Chakos, Umang Swami, Emile Latour, Yiyi Chen, Maria Fleseriu, Mohammed Milhem, Yousef Zakharia, Roula Zahr,

<h4>Background</h4>Immune checkpoint inhibitors, single or in combination, have recently become a cornerstone for the treatment of many malignancies. Ipilimumab, a CTLA-4 inhibitor, was initially FDA approved for treatment of unresectable or metastatic melanoma and subsequently in combination therapy for other cancers. Ipilimumab-induced hypophysitis (IH) risk of development varies in different ... Read more >>

Pituitary (Pituitary)
[2019, 22(5):488-496]

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Phase 1-2 study of vorinostat (SAHA), cladribine and rituximab (SCR) in relapsed B-cell non-Hodgkin lymphoma and previously untreated mantle cell lymphoma.

Stephen E Spurgeon, Kamal Sharma, David F Claxton, Christopher Ehmann, Jeffrey Pu, Sara Shimko, August Stewart, Nan Subbiah, Gundula Palmbach, Francis LeBlanc, Emile Latour, YiYi Chen, Motomi Mori, Zainul Hasanali, Elliot M Epner,

Altered DNA methylation and histone acetylation in lymphoma provided the rationale for using vorinostat (SAHA), cladribine and rituximab (SCR) in non-Hodgkin lymphomas (NHL) in this phase 1-2 study (NCT00764517). Treatment included cladribine 5 mg/m<sup>2</sup> intravenously (IV) (days 1-5), rituximab 375 mg/m<sup>2</sup> IV (weekly 4× for cycle 1 and 1×/month) and vorinostat orally ... Read more >>

Br J Haematol (British journal of haematology)
[2019, 186(6):845-854]

Cited: 2 times

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Clinical factors influencing the response to intravenous immunoglobulin treatment in cases of treatment-resistant pyoderma gangrenosum.

Carter K Haag, Alex G Ortega-Loayza, Emile Latour, Jesse J Keller, Nicole M Fett,

<b>Background:</b> Pyoderma gangrenosum (PG) is a neutrophilic disorder which classically presents as chronic, painful ulcers on the lower extremities. There is evidence supporting a potential role for intravenous immunoglobulin (IVIG) as adjuvant therapy for treatment-resistant cases; however, it is unclear which patients will most benefit from this modality of treatment ... Read more >>

J Dermatolog Treat (The Journal of dermatological treatment)
[2020, 31(7):723-726]

Cited: 1 time

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Off-label versus on-label prescribing of oral oncology agents on time to receipt of medication in patients with soft tissue sarcoma.

Victor Tran, Emile Latour, Alison Palumbo,

<h4>Purpose</h4>Off-label prescribing of oral oncology agents has been explored in the treatment of soft tissue sarcoma. The time for a prior authorization approval or rejection for an off-label use can be lengthy. The purpose of this study is to capture this burden by comparing the time it takes for patients ... Read more >>

J Oncol Pharm Pract (Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners)
[2019, 25(6):1412-1418]

Cited: 0 times

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Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk.

Erica T Goddard, Solange Bassale, Troy Schedin, Sonali Jindal, Jeremy Johnston, Ethan Cabral, Emile Latour, Traci R Lyons, Motomi Mori, Pepper J Schedin, Virginia F Borges,

<h4>Importance</h4>In women 45 years or younger, breast cancer diagnosis after childbirth increases the risk for metastasis and death, yet limited data exist to define this window of risk and associated prognostic factors.<h4>Objective</h4>To assess the window of elevated risk for metastasis following a postpartum breast cancer (PPBC) diagnosis and whether clinical ... Read more >>

JAMA Netw Open (JAMA network open)
[2019, 2(1):e186997]

Cited: 13 times

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