Full Text Journal Articles by
Author Elsa M Reyes Reyes

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Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex.

Cindy K Miranti, Sara Moore, Yongeun Kim, Venkateshwar Reddy Chappeta, Kui Wu, Biswanath De, Vijay Gokhale, Laurence H Hurley, Elsa M Reyes-Reyes,

The androgen receptor (AR) is a major driver of prostate cancer development and progression. Men who develop advanced prostate cancer often have long-term cancer control when treated with androgen-deprivation therapies (ADT). Still, their disease inevitably becomes resistant to ADT and progresses to castration-resistant prostate cancer (CRPC). ADT involves potent competitive ... Read more >>

Oncotarget (Oncotarget)
[2020, 11(19):1758-1776]

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Erratum: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex.

Cindy K Miranti, Sara Moore, Yongeun Kim, Venkateshwar Reddy Chappeta, Kui Wu, Biswanath De, Vijay Gokhale, Laurence H Hurley, Elsa M Reyes-Reyes,

[This corrects the article DOI: 10.18632/oncotarget.27589.]. ... Read more >>

Oncotarget (Oncotarget)
[2020, 11(26):2586]

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Characterizing Oligonucleotide Uptake in Cultured Cells: A Case Study Using AS1411 Aptamer.

Elsa M Reyes-Reyes, Paula J Bates,

Oligonucleotides can be designed or evolved to bind to specific DNA, RNA, protein, or small molecule targets and thereby alter the biological function of the target. The therapeutic potential of oligonucleotides targeted to intracellular molecules will depend largely on their ability to be taken up by the cells of interest, ... Read more >>

Methods Mol. Biol. (Methods in molecular biology (Clifton, N.J.))
[2019, 2036:173-186]

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Plagiochiline A Inhibits Cytokinetic Abscission and Induces Cell Death.

Nicole S Stivers, Ashraful Islam, Elsa M Reyes-Reyes, Lavona K Casson, José C Aponte, Abraham J Vaisberg, Gerald B Hammond, Paula J Bates,

We previously reported on the isolation and biological activities of plagiochiline A (1), a 2,3-secoaromadendrane-type sesquiterpenoid from the Peruvian medicinal plant, Plagiochila disticha. This compound was found to have antiproliferative effects on a variety of solid tumor cell lines, as well as several leukemia cell lines. Other researchers have also ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2018, 23(6):]

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mTOR/AMPK signaling in the brain: Cell metabolism, proteostasis and survival.

Carla Garza-Lombó, Annika Schroder, Elsa M Reyes-Reyes, Rodrigo Franco,

The mechanistic (or mammalian) target of rapamycin (mTOR) and the adenosine monophosphate-activated protein kinase (AMPK) regulate cell survival and metabolism in response to diverse stimuli such as variations in amino acid content, changes in cellular bioenergetics, oxygen levels, neurotrophic factors and xenobiotics. This Opinion paper aims to discuss the current ... Read more >>

Curr Opin Toxicol (Current opinion in toxicology)
[2018, 8:102-110]

Cited: 5 times

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LINE-1 couples EMT programming with acquisition of oncogenic phenotypes in human bronchial epithelial cells.

Elsa M Reyes-Reyes, Ivan Aispuro, Marco A Tavera-Garcia, Matthew Field, Sara Moore, Irma Ramos, Kenneth S Ramos,

Although several lines of evidence have established the central role of epithelial-to-mesenchymal-transition (EMT) in malignant progression of non-small cell lung cancers (NSCLCs), the molecular events connecting EMT to malignancy remain poorly understood. This study presents evidence that Long Interspersed Nuclear Element-1 (LINE-1) retrotransposon couples EMT programming with malignancy in human ... Read more >>

Oncotarget (Oncotarget)
[2017, 8(61):103828-103842]

Cited: 4 times

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G-quadruplex oligonucleotide AS1411 as a cancer-targeting agent: Uses and mechanisms.

Paula J Bates, Elsa M Reyes-Reyes, Mohammad T Malik, Emily M Murphy, Martin G O'Toole, John O Trent,

AS1411 is a 26-mer G-rich DNA oligonucleotide that forms a variety of G-quadruplex structures. It was identified based on its cancer-selective antiproliferative activity and subsequently determined to be an aptamer to nucleolin, a multifunctional protein that preferentially binds quadruplex nucleic acids and which is present at high levels on the ... Read more >>

Biochim Biophys Acta Gen Subj (Biochimica et biophysica acta. General subjects)
[2017, 1861(5 Pt B):1414-1428]

Cited: 34 times

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