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Author Elizabeth Sutton

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Incidence, healthcare-seeking behaviours, antibiotic use and natural history of common infection syndromes in England: results from the Bug Watch community cohort study.

Catherine M Smith, Laura J Shallcross, Peter Dutey-Magni, Anne Conolly, Christopher Fuller, Suzanne Hill, Arnoupe Jhass, Franziska Marcheselli, Susan Michie, Jennifer S Mindell, Matthew J Ridd, Georgios Tsakos, Andrew C Hayward, Ellen B Fragaszy, ,

<h4>Background</h4>Better information on the typical course and management of acute common infections in the community could inform antibiotic stewardship campaigns. We aimed to investigate the incidence, management, and natural history of a range of infection syndromes (respiratory, gastrointestinal, mouth/dental, skin/soft tissue, urinary tract, and eye).<h4>Methods</h4>Bug Watch was an online prospective ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2021, 21(1):105]

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Accuracy of Magnetic Resonance Imaging-Guided Biopsy to Verify Breast Cancer Pathologic Complete Response After Neoadjuvant Chemotherapy: A Nonrandomized Controlled Trial.

Elizabeth J Sutton, Lior Z Braunstein, Mahmoud B El-Tamer, Edi Brogi, Mary Hughes, Yolanda Bryce, Jill S Gluskin, Simon Powell, Alyssa Woosley, Audree Tadros, Varadan Sevilimedu, Danny F Martinez, Larowin Toni, Olga Smelianskaia, C Gregory Nyman, Pedram Razavi, Larry Norton, Maggie M Fung, James D Sedorovich, Virgilio Sacchini, Elizabeth A Morris,

<h4>Importance</h4>After neoadjuvant chemotherapy (NAC), pathologic complete response (pCR) is an optimal outcome and a surrogate end point for improved disease-free and overall survival. To date, surgical resection remains the only reliable method for diagnosing pCR.<h4>Objective</h4>To evaluate the accuracy of magnetic resonance imaging (MRI)-guided biopsy for diagnosing a pCR after NAC ... Read more >>

JAMA Netw Open (JAMA network open)
[2021, 4(1):e2034045]

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Changes in weekend and weekday care quality of emergency medical admissions to 20 hospitals in England during implementation of the 7-day services national health policy.

Julian Bion, Cassie Aldridge, Alan J Girling, Gavin Rudge, Jianxia Sun, Carolyn Tarrant, Elizabeth Sutton, Janet Willars, Chris Beet, Amunpreet Boyal, Peter Rees, Chris Roseveare, Mark Temple, Samuel Ian Watson, Yen-Fu Chen, Mike Clancy, Louise Rowan, Joanne Lord, Russell Mannion, Timothy Hofer, Richard Lilford,

<h4>Background</h4>In 2013, the English National Health Service launched the policy of 7-day services to improve care quality and outcomes for weekend emergency admissions.<h4>Aims</h4>To determine whether the quality of care of emergency medical admissions is worse at weekends, and whether this has changed during implementation of 7-day services.<h4>Methods</h4>Using data from 20 ... Read more >>

BMJ Qual Saf (BMJ quality & safety)
[2020, :]

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Multistakeholder Needs Assessment to Inform the Development of an mHealth-Based Ultrasound-Guided Breast Biopsy Training Program in Nigeria.

Kathleen A Lynch, Adeleye D Omisore, Thomas M Atkinson, Olusola C Famurewa, Jacqueline A Vera, T Peter Kingham, Olusegun I Alatise, Hedvig Hricak, Elizabeth A Morris, Elizabeth J Sutton, , ,

<h4>Purpose</h4>The incidence of breast cancer is rising in Nigeria, and one major barrier to care is the lack of affordable and appropriate breast cancer diagnosis by ultrasound (US)-guided biopsy. The prohibitive cost of US devices limits their availability in low- and middle-income countries. The emergence of mobile health (mHealth) imaging ... Read more >>

JCO Glob Oncol (JCO global oncology)
[2020, 6:1813-1823]

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Neonatal Survivability following Previable PPROM after Hospital Readmission for Intervention.

Felicia LeMoine, Robert C Moore, Andrew Chapple, Ferney A Moore, Elizabeth Sutton,

<b>Objective</b>  To describe our hospital's experience following expectant management of previable preterm prelabor rupture of membranes (pPPROM). <b>Study Design</b>  Retrospective review of neonatal survival and maternal and neonatal outcomes of pPPROM cases between 2012 and 2019 at a tertiary referral center in South Central Louisiana. Regression analyses were performed to ... Read more >>

AJP Rep (AJP reports)
[2020, 10(4):e395-e402]

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Regional Lymph Node Involvement Among Patients With De Novo Metastatic Breast Cancer.

Almir Bitencourt, Carolina Rossi Saccarelli, Elizabeth A Morris, Jessica Flynn, Zhigang Zhang, Atif Khan, Erin Gillespie, Oren Cahlon, Boris Mueller, John J Cuaron, Beryl McCormick, Simon N Powell, George Plitas, Pedram Razavi, Katja Pinker, Christopher C Riedl, Elizabeth J Sutton, Lior Z Braunstein,

<h4>Importance</h4>Regional nodal irradiation (RNI) for node-positive breast cancer reduces distant metastases and improves survival, albeit with limited reduction in regional nodal recurrences. The mechanism by which RNI robustly reduces distant metastases while modestly influencing nodal recurrences (ie, the presumed target of RNI) remains unclear.<h4>Objective</h4>To determine whether some distant metastases putatively ... Read more >>

JAMA Netw Open (JAMA network open)
[2020, 3(10):e2018790]

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A Qualitative Study of Organisational Response to National Quality Standards for 7-Day Services in English Hospitals

Elizabeth Sutton, Julian Bion, Russell Mannion, Janet Willars, Elizabeth Shaw, Carolyn Tarrant,

<h4>Background: </h4> National standards are commonly used as an improvement strategy in healthcare, but organisations may respond in diverse and sometimes negative ways to external quality demands. This paper describes how a sample of NHS hospital trusts in England responded to the introduction of national standards for 7-day service (7DS), ... Read more >>

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From Concerts to COVID: Transforming the RI Convention Center into an Alternate Hospital Site in under a Month.

Sonya Naganathan, Kelly Meehan-Coussee, Scott Pasichow, Heather Rybasack-Smith, William Binder, Francesca Beaudoin, Andrew N Musits, Elizabeth Sutton, Gianna Petrone, Adam C Levine, Selim Suner,

Field hospitals have long been used to extend health care capabilities in times of crisis. In response to the pandemic and an anticipated surge in patients, Rhode Island Gov. Gina Raimondo announced a plan to create three field hospitals, or "alternate hospital sites" (AHS), totaling 1,000 beds, in order to ... Read more >>

R I Med J (2013) (Rhode Island medical journal (2013))
[2020, 103(6):8-13]

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Can Follow-up be Avoided for Probably Benign US Masses with No Enhancement on MRI?

Daly Avendano, Maria Adele Marino, Natsuko Onishi, Doris Leithner, Danny F Martinez, Peter Gibbs, Maxine Jochelson, Katja Pinker, Elizabeth A Morris, Elizabeth Jane Sutton,

<h4>Objectives</h4>To assess whether no enhancement on pre-treatment MRI can rule out malignancy of additional US mass(es) initially assessed as BI-RADS 3 or 4 in women with newly diagnosed breast cancer.<h4>Methods</h4>This retrospective study included consecutive women from 2010-2018 with newly diagnosed breast cancer; at least one additional breast mass (distinct from ... Read more >>

Eur Radiol (European radiology)
[2021, 31(2):975-982]

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Early Pregnancy Blood Pressure Elevations and Risk for Maternal and Neonatal Morbidity.

Elizabeth F Sutton, Sarah C Rogan, Samia Lopa, Danielle Sharbaugh, Matthew F Muldoon, Janet M Catov,

<h4>Objective</h4>To investigate whether women with early pregnancy elevated blood pressure (BP) or stage 1 hypertension exhibit increased risk of preeclampsia and maternal or neonatal morbidity.<h4>Methods</h4>We conducted a clinical cohort study of 18,162 women who delivered a singleton neonate from 2015 to 2018 and attended at least two prenatal appointments before ... Read more >>

Obstet Gynecol (Obstetrics and gynecology)
[2020, 136(1):129-139]

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Using the CNE as an Innovative Strategy to Support Junior Nursing Faculty Transitioning From Clinical Practice.

Patricia Kinneary, Elizabeth Sutton,

For new nurse educators, the certified nurse educator credential can be more than a mark of expertise. This article explains how two junior nurse faculty discovered that preparation for certification facilitated the change process from clinician to academic nurse educator. We describe barriers overcome on the path to certification and ... Read more >>

Nurs Educ Perspect (Nursing education perspectives)
[2020, :]

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A machine learning model that classifies breast cancer pathologic complete response on MRI post-neoadjuvant chemotherapy.

Elizabeth J Sutton, Natsuko Onishi, Duc A Fehr, Brittany Z Dashevsky, Meredith Sadinski, Katja Pinker, Danny F Martinez, Edi Brogi, Lior Braunstein, Pedram Razavi, Mahmoud El-Tamer, Virgilio Sacchini, Joseph O Deasy, Elizabeth A Morris, Harini Veeraraghavan,

BACKGROUND:For breast cancer patients undergoing neoadjuvant chemotherapy (NAC), pathologic complete response (pCR; no invasive or in situ) cannot be assessed non-invasively so all patients undergo surgery. The aim of our study was to develop and validate a radiomics classifier that classifies breast cancer pCR post-NAC on MRI prior to surgery. ... Read more >>

Breast Cancer Res (Breast cancer research : BCR)
[2020, 22(1):57]

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Harmonization of Quantitative Parenchymal Enhancement in T1 -Weighted Breast MRI.

Bas H M van der Velden, Michael J van Rijssel, Beatrice Lena, Marielle E P Philippens, Claudette E Loo, Max A A Ragusi, Sjoerd G Elias, Elizabeth J Sutton, Elizabeth A Morris, Lambertus W Bartels, Kenneth G A Gilhuijs,

<h4>Background</h4>Differences in imaging parameters influence computer-extracted parenchymal enhancement measures from breast MRI.<h4>Purpose</h4>To investigate the effect of differences in dynamic contrast-enhanced MRI acquisition parameter settings on quantitative parenchymal enhancement of the breast, and to evaluate harmonization of contrast-enhancement values with respect to flip angle and repetition time.<h4>Study type</h4>Retrospective.<h4>Phantom/populations</h4>We modeled parenchymal enhancement ... Read more >>

J Magn Reson Imaging (Journal of magnetic resonance imaging : JMRI)
[2020, 52(5):1374-1382]

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Ultrafast dynamic contrast-enhanced breast MRI may generate prognostic imaging markers of breast cancer.

Natsuko Onishi, Meredith Sadinski, Mary C Hughes, Eun Sook Ko, Peter Gibbs, Katherine M Gallagher, Maggie M Fung, Theodore J Hunt, Danny F Martinez, Amita Shukla-Dave, Elizabeth A Morris, Elizabeth J Sutton,

BACKGROUND:Ultrafast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)-derived kinetic parameters have demonstrated at least equivalent accuracy to standard DCE-MRI in differentiating malignant from benign breast lesions. However, it is unclear if they have any efficacy as prognostic imaging markers. The aim of this study was to investigate the relationship between ultrafast ... Read more >>

Breast Cancer Res (Breast cancer research : BCR)
[2020, 22(1):58]

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Paternal deficiency of complement component C1q leads to a preeclampsia-like pregnancy in wild-type female mice and vascular adaptations postpartum.

Elizabeth F Sutton, Mary Gemmel, Judith Brands, Marcia J Gallaher, Robert W Powers,

Preeclampsia is a spontaneously occurring, pregnancy-specific syndrome that is clinically diagnosed by new onset hypertension and proteinuria. Epidemiological evidence describes an association between a history of preeclampsia and increased risk for cardiovascular disease in later life; however, the mechanism(s) driving this relationship are unclear. Our study aims to leverage a ... Read more >>

Am J Physiol Regul Integr Comp Physiol (American journal of physiology. Regulatory, integrative and comparative physiology)
[2020, 318(6):R1047-R1057]

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Radiomic Signatures Derived from Diffusion-Weighted Imaging for the Assessment of Breast Cancer Receptor Status and Molecular Subtypes.

Doris Leithner, Blanca Bernard-Davila, Danny F Martinez, Joao V Horvat, Maxine S Jochelson, Maria Adele Marino, Daly Avendano, R Elena Ochoa-Albiztegui, Elizabeth J Sutton, Elizabeth A Morris, Sunitha B Thakur, Katja Pinker,

<h4>Purpose</h4>To compare annotation segmentation approaches and to assess the value of radiomics analysis applied to diffusion-weighted imaging (DWI) for evaluation of breast cancer receptor status and molecular subtyping.<h4>Procedures</h4>In this IRB-approved HIPAA-compliant retrospective study, 91 patients with treatment-naïve breast malignancies proven by image-guided breast biopsy, (luminal A, n = 49; luminal B, n = 8; ... Read more >>

Mol Imaging Biol (Molecular imaging and biology)
[2020, 22(2):453-461]

Cited: 6 times

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Survival Outcomes of Screening with Breast MRI in Women at Elevated Risk of Breast Cancer.

Min Sun Bae, Janice S Sung, Blanca Bernard-Davila, Elizabeth J Sutton, Christopher E Comstock, Elizabeth A Morris,

<h4>Objective</h4>To determine survival outcomes in women with breast cancer detected at combined screening with breast MRI and mammography versus screening mammography alone.<h4>Methods</h4>This is an institutional review board-approved retrospective study, and the need for informed consent was waived. A total of 3002 women with an increased risk of breast cancer were ... Read more >>

J Breast Imaging (Journal of breast imaging)
[2020, 2(1):29-35]

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Nitric oxide signaling in pregnancy and preeclampsia.

Elizabeth F Sutton, Mary Gemmel, Robert W Powers,

While the etiology of preeclampsia continues to be elucidated, it is clear that preeclampsia is a complex obstetrical syndrome associated with maternal vascular dysfunction within which impairments in nitric oxide (NO) signaling likely play a key role in driving disease progression and severity. The goal of this review is to ... Read more >>

Nitric Oxide (Nitric oxide : biology and chemistry)
[2020, 95:55-62]

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Incidence of benign and malignant peri-implant fluid collections and masses on magnetic resonance imaging in women with silicone implants.

Elizabeth J Sutton, Brittany Z Dashevsky, Elizabeth J Watson, Neelam Tyagi, Blanca Bernard-Davila, Danny Martinez, Ahmet Dogan, Steven M Horwitz, Peter G Cordeiro, Elizabeth A Morris,

<h4>Background</h4>To assess the incidence of benign and malignant peri-implant fluid collections and/or masses on magnetic resonance imaging (MRI) in women with silicone implants who are being screened for silent implant rupture.<h4>Methods</h4>The institutional review board approved this HIPAA-compliant retrospective study and waived informed consent. Women who underwent silicone implant oncoplastic and/or ... Read more >>

Cancer Med (Cancer medicine)
[2020, 9(10):3261-3267]

Cited: 1 time

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Differentiation between subcentimeter carcinomas and benign lesions using kinetic parameters derived from ultrafast dynamic contrast-enhanced breast MRI.

Natsuko Onishi, Meredith Sadinski, Peter Gibbs, Katherine M Gallagher, Mary C Hughes, Eun Sook Ko, Brittany Z Dashevsky, Dattesh D Shanbhag, Maggie M Fung, Theodore M Hunt, Danny F Martinez, Amita Shukla-Dave, Elizabeth A Morris, Elizabeth J Sutton,

<h4>Objectives</h4>This study aims to evaluate ultrafast DCE-MRI-derived kinetic parameters that reflect contrast agent inflow effects in differentiating between subcentimeter BI-RADS 4-5 breast carcinomas and benign lesions.<h4>Methods</h4>We retrospectively reviewed consecutive 3-T MRI performed from February to October 2017, during which ultrafast DCE-MRI was performed as part of a hybrid clinical protocol ... Read more >>

Eur Radiol (European radiology)
[2020, 30(2):756-766]

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Magnitude and modifiers of the weekend effect in hospital admissions: a systematic review and meta-analysis.

Yen-Fu Chen, Xavier Armoiry, Caroline Higenbottam, Nicholas Cowley, Rajna Basra, Samuel Ian Watson, Carolyn Tarrant, Amunpreet Boyal, Elizabeth Sutton, Chia-Wei Wu, Cassie P Aldridge, Amy Gosling, Richard Lilford, Julian Bion,

<h4>Objective</h4>To examine the magnitude of the weekend effect, defined as differences in patient outcomes between weekend and weekday hospital admissions, and factors influencing it.<h4>Design</h4>A systematic review incorporating Bayesian meta-analyses and meta-regression.<h4>Data sources</h4>We searched seven databases including MEDLINE and EMBASE from January 2000 to April 2015, and updated the MEDLINE search ... Read more >>

BMJ Open (BMJ open)
[2019, 9(6):e025764]

Cited: 5 times

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Association between CT-texture-derived tumor heterogeneity, outcomes, and BRCA mutation status in patients with high-grade serous ovarian cancer.

Andreas Meier, Harini Veeraraghavan, Stephanie Nougaret, Yulia Lakhman, Ramon Sosa, Robert A Soslow, Elizabeth J Sutton, Hedvig Hricak, Evis Sala, Hebert A Vargas,

<h4>Purpose</h4>To assess the associations between inter-site texture heterogeneity parameters derived from computed tomography (CT), survival, and BRCA mutation status in women with high-grade serous ovarian cancer (HGSOC).<h4>Materials and methods</h4>Retrospective study of 88 HGSOC patients undergoing CT and BRCA mutation status testing prior to primary cytoreductive surgery. Associations between texture metrics-namely ... Read more >>

Abdom Radiol (NY) (Abdominal radiology (New York))
[2019, 44(6):2040-2047]

Cited: 4 times

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Characterization of Sub-1 cm Breast Lesions Using Radiomics Analysis.

Peter Gibbs, Natsuko Onishi, Meredith Sadinski, Katherine M Gallagher, Mary Hughes, Danny F Martinez, Elizabeth A Morris, Elizabeth J Sutton,

BACKGROUND:Small breast lesions are difficult to visually categorize due to the inherent lack of morphological and kinetic detail. PURPOSE:To assess the efficacy of radiomics analysis in discriminating small benign and malignant lesions utilizing model free parameter maps. STUDY TYPE:Retrospective, single center. POPULATION:In all, 149 patients, with a total of 165 ... Read more >>

J Magn Reson Imaging (Journal of magnetic resonance imaging : JMRI)
[2019, 50(5):1468-1477]

Cited: 4 times

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Making infection prevention and control everyone's business? Hospital staff views on patient involvement.

Elizabeth Sutton, Liz Brewster, Carolyn Tarrant,

<h4>Context</h4>Ensuring an infection-free environment is increasingly seen as requiring the contribution of staff, patients and visitors. There is limited evidence, however, about how staff feel about collaborating with patients and relatives to co-produce that environment.<h4>Aims</h4>This study aims to understand how hospital staff perceive the involvement of patients and relatives in ... Read more >>

Health Expect (Health expectations : an international journal of public participation in health care and health policy)
[2019, 22(4):650-656]

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A Guide to Postexamination Analysis: Utilizing Data to Increase Reliability and Ensure Objectivity.

Maryann Magaldi, Patricia Kinneary, Georgina Colalillo, Elizabeth Sutton,

Nurse Educ (Nurse educator)
[2019, 44(2):61-63]

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