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Author Elizabeth A Davis

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Correction to: Acute hyperglycaemia does not have a consistent adverse effect on exercise performance in recreationally active young people with type 1 diabetes: a randomised crossover in-clinic study.

Karen M Rothacker, Sam Armstrong, Grant J Smith, Nat Benjanuvatra, Brendan Lay, Peter Adolfsson, Timothy W Jones, Paul A Fournier, Elizabeth A Davis,

Diabetologia (Diabetologia)
[2021, 64(8):1899]

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Identifying the core concepts of pharmacology education.

Paul J White, Elizabeth A Davis, Marina Santiago, Tom Angelo, Alison Shield, Anna-Marie Babey, Barbara Kemp-Harper, Gregg Maynard, Hesham S Al-Sallami, Ian F Musgrave, Lynette B Fernandes, Suong N T Ngo, Tina Hinton,

Pharmacology education currently lacks an agreed knowledge curriculum. Evidence from physics and biology education indicates that core concepts are useful and effective structures around which such a curriculum can be designed to facilitate student learning. Building on previous work, we developed a novel, criterion-based method to identify the core concepts ... Read more >>

Pharmacol Res Perspect (Pharmacology research & perspectives)
[2021, 9(4):e00836]

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Continuous Glucose Monitoring Improves Glycemic Outcomes in Children With Type 1 Diabetes: Real-world Data From a Population-Based Clinic.

Elaine E Sanderson, Mary B Abraham, Grant J Smith, Jenny A Mountain, Timothy W Jones, Elizabeth A Davis,

Diabetes Care (Diabetes care)
[2021, :]

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Evaluation of protocol amendments to the Environmental Determinants of Islet Autoimmunity (ENDIA) study during the COVID-19 pandemic.

Megan A S Penno, Amanda J Anderson, Rebecca L Thomson, Kelly McGorm, Simon C Barry, Peter G Colman, Maria E Craig, Elizabeth A Davis, Mark Harris, Aveni Haynes, Grant Morahan, Helena Oakey, William D Rawlinson, Richard O Sinnott, Georgia Soldatos, Peter J Vuillermin, John M Wentworth, Leonard C Harrison, Jennifer J Couper, ,

Diabet Med (Diabetic medicine : a journal of the British Diabetic Association)
[2021, :e14638]

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Impact of Hybrid Closed Loop Therapy on Hypoglycemia Awareness in Individuals with Type 1 Diabetes and Impaired Hypoglycemia Awareness.

Marie-Anne Burckhardt, Mary B Abraham, Julie Dart, Grant J Smith, Nirubasini Paramalingam, Joanne O'Dea, Martin de Bock, Elizabeth A Davis, Timothy W Jones,

<b><i>Objective:</i></b> This study evaluated the efficacy of using a hybrid closed loop (HCL) system in restoring hypoglycemia awareness in individuals with impaired awareness of hypoglycemia (IAH). <b><i>Research Design and Methods:</i></b> Participants with IAH (Gold score ≥4) were recruited into a randomized crossover pilot study. They participated in two 8-week periods ... Read more >>

Diabetes Technol Ther (Diabetes technology & therapeutics)
[2021, 23(7):482-490]

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Advances in Exercise and Nutrition as Therapy in Diabetes.

Michael C Riddell, Elizabeth A Davis, Elizabeth J Mayer-Davis, Anna Kahkoska, Dessi P Zaharieva,

Diabetes Technol Ther (Diabetes technology & therapeutics)
[2021, 23(S2):S131-S142]

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Additional Insulin is Required in Both the Early and Late Postprandial Periods for Meals High in Protein and Fat: A Randomised Trial.

Barbara Keating, Carmel E M Smart, Amelia J Harray, Nirubasini Paramalingam, Grant Smith, Timothy W Jones, Bruce R King, Elizabeth A Davis,

<h4>Context</h4>The pattern and quantity of insulin required for high protein high fat (HPHF) meals is not well understood.<h4>Objective</h4>This study aimed to determine the amount and delivery pattern of insulin required to maintain euglycaemia for five hours after consuming a HPHF meal compared to a low protein low fat (LPLF) meal.<h4>Design</h4>Randomised ... Read more >>

J Clin Endocrinol Metab (The Journal of clinical endocrinology and metabolism)
[2021, :]

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Acute hyperglycaemia does not have a consistent adverse effect on exercise performance in recreationally active young people with type 1 diabetes: a randomised crossover in-clinic study.

Karen M Rothacker, Sam Armstrong, Grant J Smith, Nat Benjanuvatra, Brendan Lay, Peter Adolfsson, Timothy W Jones, Paul A Fournier, Elizabeth A Davis,

<h4>Aims/hypothesis</h4>In individuals with type 1 diabetes, chronic hyperglycaemia impairs aerobic fitness. However, the effect of acute marked hyperglycaemia on aerobic fitness is unclear, and the impact of insulin level has not been examined. In this study, we explored if acute hyperglycaemia with higher or low insulin levels affects [Formula: see ... Read more >>

Diabetologia (Diabetologia)
[2021, 64(8):1737-1748]

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Use of linked administrative and laboratory data to confirm that serum 25(OH)D levels in pregnant women can be predicted from satellite estimates of ultraviolet radiation.

Kate M Miller, Robyn M Lucas, Elizabeth A Davis, Prue H Hart, Nicholas H de Klerk,

<h4>Background</h4>Serum 25 hydroxyvitamin D [25(OH)D] levels of pregnant women have been linked to various health outcomes in their offspring. Satellite-derived ultraviolet radiation (UVR) data have been used as a proxy for 25(OH)D levels, as individual-level cohort studies are time-consuming, costly and only feasible for common outcomes.<h4>Methods</h4>Data on 25(OH)D levels from ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2021, 50(1):303-313]

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Two decades of increasing incidence of childhood-onset type 2 diabetes in Western Australia (2000-2019).

Aveni Haynes, Jacqueline A Curran, Elizabeth A Davis,

Med J Aust (The Medical journal of Australia)
[2021, 214(6):285-285.e1]

Cited: 0 times

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Less Nocturnal Hypoglycemia but Equivalent Time in Range Among Adults with Type 1 Diabetes Using Insulin Pumps Versus Multiple Daily Injections.

Sybil A McAuley, Sara Vogrin, Melissa H Lee, Barbora Paldus, Steven Trawley, Martin I de Bock, Mary B Abraham, Leon A Bach, Morton G Burt, Neale D Cohen, Peter G Colman, Elizabeth A Davis, Christel Hendrieckx, D Jane Holmes-Walker, Alicia J Jenkins, Joey Kaye, Anthony C Keech, Kavita Kumareswaran, Richard J MacIsaac, Roland W McCallum, Catriona M Sims, Jane Speight, Stephen N Stranks, Vijaya Sundararajan, Glenn M Ward, Timothy W Jones, David N O'Neal, ,

<b><i>Background:</i></b> This prerandomization analysis from the Australian HCL-Adult trial (registration number: ACTRN12617000520336) compared masked continuous glucose monitoring (CGM) metrics among adults using insulin pumps versus multiple daily injections (MDIs), who were all self-monitoring blood glucose (SMBG). <b><i>Methods:</i></b> Adults with type 1 diabetes, using an insulin pump or MDIs without real-time ... Read more >>

Diabetes Technol Ther (Diabetes technology & therapeutics)
[2021, 23(6):460-466]

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Effect of Exercise Intensity on Exogenous Glucose Requirements to Maintain Stable Glycemia At High Insulin Levels in Type 1 Diabetes.

Vinutha B Shetty, Paul A Fournier, Nirubasini Paramalingam, Wayne Soon, Heather C Roby, Timothy W Jones, Elizabeth A Davis,

<h4>Context</h4>Under basal insulin levels, there is an inverted U relationship between exercise intensity and exogenous glucose requirements to maintain stable blood glucose levels in type 1 diabetes (T1D), with no glucose required for intense exercise (80% V̇O2 peak), implying that high-intensity exercise is not conducive to hypoglycemia.<h4>Objective</h4>This work aimed to ... Read more >>

J Clin Endocrinol Metab (The Journal of clinical endocrinology and metabolism)
[2021, 106(1):e83-e93]

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Copeptin Kinetics and Its Relationship to Osmolality During Rehydration for Diabetic Ketoacidosis in Children.

Marie-Anne Burckhardt, Verena Gotta, Svetlana Beglinger, Luzia Renggli, Sara Bachmann, Melanie Hess, Katharina Rentsch, Marc Pfister, Gilbert Koch, Elizabeth A Davis, Urs Zumsteg, Timothy W Jones, Gabor Szinnai,

<h4>Context</h4>Copeptin is a surrogate marker for arginine vasopressin (AVP) release in response to hyperosmolal stimuli such as diabetic ketoacidosis (DKA).<h4>Objective</h4>The objective of this work is to characterize kinetics of copeptin and osmolality, and their dynamic relationship during rehydration and insulin therapy in children with type 1 diabetes (T1D) and DKA.<h4>Design ... Read more >>

J Clin Endocrinol Metab (The Journal of clinical endocrinology and metabolism)
[2020, 105(11):]

Cited: 1 time

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Six Months of Hybrid Closed-Loop Versus Manual Insulin Delivery With Fingerprick Blood Glucose Monitoring in Adults With Type 1 Diabetes: A Randomized, Controlled Trial.

Sybil A McAuley, Melissa H Lee, Barbora Paldus, Sara Vogrin, Martin I de Bock, Mary B Abraham, Leon A Bach, Morton G Burt, Neale D Cohen, Peter G Colman, Elizabeth A Davis, Christel Hendrieckx, D Jane Holmes-Walker, Joey Kaye, Anthony C Keech, Kavita Kumareswaran, Richard J MacIsaac, Roland W McCallum, Catriona M Sims, Jane Speight, Stephen N Stranks, Vijaya Sundararajan, Steven Trawley, Glenn M Ward, Alicia J Jenkins, Timothy W Jones, David N O'Neal, ,

<h4>Objective</h4>To investigate glycemic and psychosocial outcomes with hybrid closed-loop (HCL) versus user-determined insulin dosing with multiple daily injections (MDI) or insulin pump (i.e., standard therapy for most adults with type 1 diabetes).<h4>Research design and methods</h4>Adults with type 1 diabetes using MDI or insulin pump without continuous glucose monitoring (CGM) were ... Read more >>

Diabetes Care (Diabetes care)
[2020, 43(12):3024-3033]

Cited: 1 time

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Vascular Effects of ACE (Angiotensin-Converting Enzyme) Inhibitors and Statins in Adolescents With Type 1 Diabetes.

Scott T Chiesa, M Loredana Marcovecchio, Paul Benitez-Aguirre, Fergus J Cameron, Maria E Craig, Jennifer J Couper, Elizabeth A Davis, R Neil Dalton, Denis Daneman, Kim C Donaghue, Timothy W Jones, Farid H Mahmud, Sally M Marshall, H Andrew W Neil, David B Dunger, John E Deanfield, ,

An increased albumin-creatinine ratio within the normal range can identify adolescents at higher risk of developing adverse cardio-renal outcomes as they progress into adulthood. Utilizing a parallel randomized controlled trial and observational cohort study, we characterized the progression of vascular phenotypes throughout this important period and investigated the effect of ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2020, 76(6):1734-1743]

Cited: 3 times

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Biomarkers associated with early stages of kidney disease in adolescents with type 1 diabetes.

Maria Loredana Marcovecchio, Marco Colombo, Raymond Neil Dalton, Paul M McKeigue, Paul Benitez-Aguirre, Fergus J Cameron, Scott T Chiesa, Jennifer J Couper, Maria E Craig, Denis Daneman, Elizabeth A Davis, John E Deanfield, Kim C Donaghue, Timothy W Jones, Farid H Mahmud, Sally M Marshall, Andrew Neil, Helen M Colhoun, David B Dunger, ,

<h4>Objectives</h4>To identify biomarkers of renal disease in adolescents with type 1 diabetes (T1D) and to compare findings in adults with T1D.<h4>Methods</h4>Twenty-five serum biomarkers were measured, using a Luminex platform, in 553 adolescents (median [interquartile range] age: 13.9 [12.6, 15.2] years), recruited to the Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial. ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2020, 21(7):1322-1332]

Cited: 0 times

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Ghrelin Signaling Affects Feeding Behavior, Metabolism, and Memory through the Vagus Nerve.

Elizabeth A Davis, Hallie S Wald, Andrea N Suarez, Jasenka Zubcevic, Clarissa M Liu, Alyssa M Cortella, Anna K Kamitakahara, Jaimie W Polson, Myrtha Arnold, Harvey J Grill, Guillaume de Lartigue, Scott E Kanoski,

Vagal afferent neuron (VAN) signaling sends information from the gut to the brain and is fundamental in the control of feeding behavior and metabolism [1]. Recent findings reveal that VAN signaling also plays a critical role in cognitive processes, including affective motivational behaviors and hippocampus (HPC)-dependent memory [2-5]. VANs, located ... Read more >>

Curr Biol (Current biology : CB)
[2020, 30(22):4510-4518.e6]

Cited: 7 times

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Changes in pancreatic exocrine function in young at-risk children followed to islet autoimmunity and type 1 diabetes in the ENDIA study.

Megan A S Penno, Helena Oakey, Priya Augustine, Mario Taranto, Simon C Barry, Peter G Colman, Maria E Craig, Elizabeth A Davis, Lynne C Giles, Mark Harris, Aveni Haynes, Kelly McGorm, Grant Morahan, Claire Morbey, William D Rawlinson, Richard O Sinnott, Georgia Soldatos, Rebecca L Thomson, Peter J Vuillermin, John M Wentworth, Leonard C Harrison, Jennifer J Couper,

BACKGROUNDS:We aimed to monitor pancreatic exocrine function longitudinally in relation to the development of islet autoimmunity (IA) and type 1 diabetes (T1D) in at-risk children with a first-degree relative with T1D, who were followed prospectively in the Environmental Determinants of Islet Autoimmunity (ENDIA) study. METHODS:Fecal elastase-1 (FE-1) concentration was measured ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2020, 21(6):945-949]

Cited: 1 time

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Incidence of type 1 diabetes in 0 to 14 year olds in Australia from 2002 to 2017.

Aveni Haynes, Max K Bulsara, Phil Bergman, Fergus Cameron, Jennifer Couper, Maria E Craig, Karen Demangone, Stephanie Johnson, Antony Lafferty, Angela Titmuss, Elizabeth A Davis,

<h4>Objective</h4>To determine the incidence of childhood onset type 1 diabetes in Australia from 2002 to 2017, and analyze incidence rate trends by calendar year, sex, and age at diagnosis.<h4>Research design and methods</h4>Children newly diagnosed with type 1 diabetes aged <15  years between 2002 and 2017 were identified from the National ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2020, 21(5):707-712]

Cited: 1 time

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Central sensory-motor crosstalk in the neural gut-brain axis.

Coltan G Parker, Megan J Dailey, Heidi Phillips, Elizabeth A Davis,

The neural gut-brain axis consists of viscerosensory and autonomic motor neurons innervating the gastrointestinal (GI) tract. Sensory neurons transmit nutrient-related and non-nutrient-related information to the brain, while motor neurons regulate GI motility and secretion. Previous research provides an incomplete picture of the brain nuclei that are directly connected with the ... Read more >>

Auton Neurosci (Autonomic neuroscience : basic & clinical)
[2020, 225:102656]

Cited: 3 times

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Advances in Exercise, Physical Activity, and Diabetes.

Dessi P Zaharieva, Sarah McGaugh, Elizabeth A Davis, Michael C Riddell,

Diabetes Technol Ther (Diabetes technology & therapeutics)
[2020, 22(S1):S109-S118]

Cited: 2 times

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Effect of frequency of sensor use on glycaemic control in individuals on sensor-augmented pump therapy with and without Predictive Low Glucose Management System.

Mary B Abraham, Grant J Smith, Jennifer A Nicholas, Janice M Fairchild, Bruce R King, Geoffrey R Ambler, Fergus J Cameron, Elizabeth A Davis, Timothy W Jones, ,

Improved frequency of sensor use improves glycaemic control. Furthermore, there is no deterioration of glycaemic control with increased sensor use in individuals on Predictive Low Glucose Management (PLGM) system. Younger children are more likely to have better sensor uptake than older children. ... Read more >>

Diabetes Res Clin Pract (Diabetes research and clinical practice)
[2020, 159:107989]

Cited: 0 times

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Clinical characteristics of Western Australian children diagnosed with type 2 diabetes before 10 years of age.

Jacqueline A Curran, Aveni Haynes, Elizabeth A Davis,

Med J Aust (The Medical journal of Australia)
[2020, 212(2):95-95.e1]

Cited: 1 time

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Higher frequency of vertebrate-infecting viruses in the gut of infants born to mothers with type 1 diabetes.

Ki Wook Kim, Digby W Allen, Thomas Briese, Jennifer J Couper, Simon C Barry, Peter G Colman, Andrew M Cotterill, Elizabeth A Davis, Lynne C Giles, Leonard C Harrison, Mark Harris, Aveni Haynes, Jessica L Horton, Sonia R Isaacs, Komal Jain, Walter I Lipkin, Kelly McGorm, Grant Morahan, Claire Morbey, Ignatius C N Pang, Anthony T Papenfuss, Megan A S Penno, Richard O Sinnott, Georgia Soldatos, Rebecca L Thomson, Peter Vuillermin, John M Wentworth, Marc R Wilkins, William D Rawlinson, Maria E Craig, ,

<h4>Background</h4>Microbial exposures in utero and early life shape the infant microbiome, which can profoundly impact on health. Compared to the bacterial microbiome, very little is known about the virome. We set out to characterize longitudinal changes in the gut virome of healthy infants born to mothers with or without type ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2020, 21(2):271-279]

Cited: 4 times

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Hypothalamus-hippocampus circuitry regulates impulsivity via melanin-concentrating hormone.

Emily E Noble, Zhuo Wang, Clarissa M Liu, Elizabeth A Davis, Andrea N Suarez, Lauren M Stein, Linda Tsan, Sarah J Terrill, Ted M Hsu, A-Hyun Jung, Lauren M Raycraft, Joel D Hahn, Martin Darvas, Alyssa M Cortella, Lindsey A Schier, Alexander W Johnson, Matthew R Hayes, Daniel P Holschneider, Scott E Kanoski,

Behavioral impulsivity is common in various psychiatric and metabolic disorders. Here we identify a hypothalamus to telencephalon neural pathway for regulating impulsivity involving communication from melanin-concentrating hormone (MCH)-expressing lateral hypothalamic neurons to the ventral hippocampus subregion (vHP). Results show that both site-specific upregulation (pharmacological or chemogenetic) and chronic downregulation (RNA ... Read more >>

Nat Commun (Nature communications)
[2019, 10(1):4923]

Cited: 8 times

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