Full Text Journal Articles by
Author Elisabeth Maillart

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Multiple cervical dissections after Rituximab.

Thomas Roux, Savine Vicart, Natalia Shor, Raphaël De Paz, Anne Léger, Caroline Papeix, Elisabeth Maillart,

Mult Scler Relat Disord (Multiple sclerosis and related disorders)
[2020, 42:102105]

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Outcome and risk of recurrence in a large cohort of idiopathic longitudinally extensive transverse myelitis without AQP4/MOG antibodies.

Elisabeth Maillart, Françoise Durand-Dubief, Céline Louapre, Bertrand Audoin, Bertrand Bourre, Nathalie Derache, Jonathan Ciron, Nicolas Collongues, Jérome de Sèze, Mikael Cohen, Christine Lebrun-Frenay, Nawel Hadhoum, Hélène Zéphir, Romain Deschamps, Clarisse Carra-Dallière, Pierre Labauge, Philippe Kerschen, Alexis Montcuquet, Sandrine Wiertlewski, David Laplaud, Gwenaëlle Runavot, Sandra Vukusic, Caroline Papeix, Romain Marignier, ,

BACKGROUND:Longitudinally extensive transverse myelitis (LETM) is classically related to aquaporin (AQP4)-antibodies (Ab) neuromyelitis optica spectrum disorders (NMOSD) or more recently to myelin oligodendrocyte glycoprotein (MOG)-Ab associated disease. However, some patients remain negative for any diagnosis, despite a large work-up including AQP4-Ab and MOG-Ab. Data about natural history, disability outcome, and ... Read more >>

J Neuroinflammation (Journal of neuroinflammation)
[2020, 17(1):128]

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A comparative evaluation of different NeuroMyelitis Optica Spectrum Disorder sets criteria

Caroline Papeix, Ysoline Beigneux, Elisabeth Maillart, Jérôme de Seze, Catherine Lubetzki, Sandra Vukusic, Nicolas Collongues, Romain Marignier,

Abstract Background Three different sets of criteria have been proposed for the diagnosis of neuromyelitis optica spectrum disorders (NMOSD). OBJECTIVE To compare the specificity, sensitivity and diagnostic accuracy of the three different sets of NMOSD criteria, in patients presenting with inflammatory disorders of the central nervous system ... Read more >>

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Dramatic efficacy of ofatumumab in refractory pediatric-onset AQP4-IgG neuromyelitis optica spectrum disorder.

Elisabeth Maillart, Florence Renaldo, Caroline Papeix, Kumaran Deiva, Julie Bonheur, Teresa Kwon, Odile Boespflug-Tanguy, David Germanaud, Romain Marignier,

Neurol Neuroimmunol Neuroinflamm (Neurology(R) neuroimmunology & neuroinflammation)
[2020, 7(3):]

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Evaluation of efficacy and tolerability of first-line therapies in NMOSD.

Julien Poupart, Jonathan Giovannelli, Romain Deschamps, Bertrand Audoin, Jonathan Ciron, Elisabeth Maillart, Caroline Papeix, Nicolas Collongues, Bertrand Bourre, Mickael Cohen, Sandrine Wiertlewski, Olivier Outteryck, David Laplaud, Sandra Vukusic, Romain Marignier, Hélène Zephir, ,

OBJECTIVE:To compare the efficacy and the risk of severe infectious events of immunosuppressive agents used early as first-line therapy in patients with neuromyelitis optica spectrum disorder (NMOSD). METHODS:We retrospectively included patients with NMOSD and a seropositive status for aquaporin 4 or myelin oligodendrocyte glycoprotein antibodies beginning first-line immunosuppressants within 3 ... Read more >>

Neurology (Neurology)
[2020, 94(15):e1645-e1656]

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Individual mapping of innate immune cell activation is a candidate marker of patient-specific trajectories of disability worsening in Multiple Sclerosis.

Benedetta Bodini, Emilie Poirion, Matteo Tonietto, Charline Benoit, Raffaele Palladino, Elisabeth Maillart, Erika Portera, Marco Battaglini, Geraldine Bera, Bertrand Kuhnast, Celine Louapre, Michel Bottlaender, Bruno Stankoff,

Objective: To develop a novel approach to generate individual maps of white matter (WM) innate immune cell activation using 18F-DPA-714 translocator protein (TSPO) positron emission tomography (PET), and to explore the relationship between these maps and individual trajectories of disability worsening in patients with multiple sclerosis (MS). Methods: Patients with ... Read more >>

J. Nucl. Med. (Journal of nuclear medicine : official publication, Society of Nuclear Medicine)
[2020, :]

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Secondary hypersomnia as an initial manifestation of neuromyelitis optica spectrum disorders.

Ysoline Beigneux, Isabelle Arnulf, Perrine Guillaume-Jugnot, Smaranda Leu-Semenescu, Elisabeth Maillart, Catherine Lubetzki, Olivier Benveniste, Caroline Papeix,

The identification of AQP4-IgG, a specific and pathogenic antibody of NMO/SD has led to a broadening of the clinical spectrum of manifestations of NMO/SD including the presence of encephalic symptoms. Lesions are often distributed on peri‑ependymal area and sometimes affected the diencephalon leading to sleep disorders. We report a case ... Read more >>

Mult Scler Relat Disord (Multiple sclerosis and related disorders)
[2020, 38:101869]

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Expert opinion: Criteria for second-line treatment failure in patients with multiple sclerosis.

Patrick Vermersch, Jérôme De Sèze, Pierre Clavelou, Françoise Durand-Dubief, Elisabeth Maillart, Claude Mekies, Thibault Moreau, Caroline Papeix, Ayman Tourbah, Pierre Labauge,

OBJECTIVES:In the management of multiple sclerosis (MS), defining criteria for identification of suboptimal therapy responses and switching treatment is essential to avoid worsening. Despite the lack of a standardised definition, criteria for first-line treatment are well documented in the literature, based on clinical measures or magnetic resonance imaging (MRI) (gadolinium ... Read more >>

Mult Scler Relat Disord (Multiple sclerosis and related disorders)
[2019, 36:101406]

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Progressive Multifocal Leukoencephalopathy Incidence and Risk Stratification Among Natalizumab Users in France.

Sandra Vukusic, Fabien Rollot, Romain Casey, Julie Pique, Romain Marignier, Guillaume Mathey, Gilles Edan, David Brassat, Aurélie Ruet, Jérôme De Sèze, Elisabeth Maillart, Hélène Zéphir, Pierre Labauge, Nathalie Derache, Christine Lebrun-Frenay, Thibault Moreau, Sandrine Wiertlewski, Eric Berger, Xavier Moisset, Audrey Rico-Lamy, Bruno Stankoff, Caroline Bensa, Eric Thouvenot, Olivier Heinzlef, Abdullatif Al-Khedr, Bertrand Bourre, Mathieu Vaillant, Philippe Cabre, Alexis Montcuquet, Abir Wahab, Jean-Philippe Camdessanché, Ayman Tourbah, Anne-Marie Guennoc, Karolina Hankiewicz, Ivania Patry, Chantal Nifle, Nicolas Maubeuge, Céline Labeyrie, Patrick Vermersch, David-Axel Laplaud, ,

Importance:Risk of developing progressive multifocal leukoencephalopathy (PML) is the major barrier to using natalizumab for patients with multiple sclerosis (MS). To date, the association of risk stratification with PML incidence has not been evaluated. Objective:To describe the temporal evolution of PML incidence in France before and after introduction of risk ... Read more >>

JAMA Neurol (JAMA neurology)
[2019, :]

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Evaluation of treatment response in adults with relapsing MOG-Ab-associated disease.

Alvaro Cobo-Calvo, María Sepúlveda, Fabien Rollot, Thais Armangué, Anne Ruiz, Elisabeth Maillart, Caroline Papeix, Bertrand Audoin, Helene Zephir, Damien Biotti, Jonathan Ciron, Francoise Durand-Dubief, Nicolas Collongues, Xavier Ayrignac, Pierre Labauge, Eric Thouvenot, Bertrand Bourre, Alexis Montcuquet, Mikael Cohen, Romain Deschamps, Nuria Solà-Valls, Sara Llufriu, Jerome De Seze, Yolanda Blanco, Sandra Vukusic, Albert Saiz, Romain Marignier,

BACKGROUND:Myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) are related to several acquired demyelinating syndromes in adults, but the therapeutic approach is currently unclear. We aimed to describe the response to different therapeutic strategies in adult patients with relapsing MOG-Ab-associated disease. METHODS:This is a retrospective study conducted in France and Spain including 125 ... Read more >>

J Neuroinflammation (Journal of neuroinflammation)
[2019, 16(1):134]

Cited: 2 times

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Frequency and characteristics of short versus longitudinally extensive myelitis in adults with MOG antibodies: A retrospective multicentric study.

Jonathan Ciron, Alvaro Cobo-Calvo, Bertrand Audoin, Bertrand Bourre, David Brassat, Mikael Cohen, Nicolas Collongues, Romain Deschamps, Françoise Durand-Dubief, David Laplaud, Elisabeth Maillart, Caroline Papeix, Hélène Zephir, Matthieu Bereau, Bruno Brochet, Clarisse Carra-Dallière, Nathalie Derache, Clarisse Gagou-Scherer, Carole Henry, Philippe Kerschen, Guillaume Mathey, Nicolas Maubeuge, Aude Maurousset, Alexis Montcuquet, Thibault Moreau, Christophe Prat, Frédéric Taithe, Eric Thouvenot, Ayman Tourbah, Fabien Rollot, Sandra Vukusic, Romain Marignier,

OBJECTIVES:We aim to (1) determine the frequency and distinctive features of short myelitis (SM) and longitudinally extensive transverse myelitis (LETM) in a cohort of adults with myelin oligodendrocyte glycoprotein (MOG)-antibody (Ab)-associated myelitis and (2) determine baseline prognostic factors among MOG-Ab-positive patients whose disease started with myelitis. MATERIAL AND METHODS:We retrospectively ... Read more >>

Mult. Scler. (Multiple sclerosis (Houndmills, Basingstoke, England))
[2019, :1352458519849511]

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Severe transient myopathy in a patient with progressive multiple sclerosis and high-dose biotin.

Elisabeth Maillart, Fanny Mochel, Cécile Acquaviva, Thierry Maisonobe, Bruno Stankoff,

Neurology (Neurology)
[2019, 92(22):1060-1062]

Cited: 1 time

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Correction to: Usefulness of MOG-antibody titres at first episode to predict the future clinical course in adults.

Alvaro Cobo-Calvo, María Sepúlveda, Hyacintha d'Indy, Thais Armangué, Anne Ruiz, Elisabeth Maillart, Caroline Papeix, Bertrand Audoin, Helene Zephir, Damien Biotti, Jonathan Ciron, Francoise Durand-Dubief, Nicolas Collongues, Xavier Ayrignac, Pierre Labauge, Eric Thouvenot, Alexis Montcuquet, Romain Deschamps, Nuria Solà-Valls, Sara Llufriu, Yolanda Blanco, Jerome de Seze, Sandra Vukusic, Albert Saiz, Romain Marignier, , ,

The original version of this article unfortunately contained a mistake. ... Read more >>

J. Neurol. (Journal of neurology)
[2019, 266(4):816]

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Early radiological features of severe longitudinally extensive transverse myelitis over time.

Samuel Cattan, Caroline Papeix, David Grabli, Olivier Casez, Natalia Shor, Mihaela Bustuchina Vlaicu, Savine Vicart, Céline Louapre, Elisabeth Maillart,

J. Neurol. Sci. (Journal of the neurological sciences)
[2019, 400:7-9]

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False hepatitis B and C viral serologies in patients with multiple sclerosis receiving high-dose biotin.

Valérie Pourcher, Eve Todesco, Claire Dubois, Coralie Pallier, Catherine Lubetzki, Celine Louapre, Caroline Papeix, Elisabeth Maillart,

Mult. Scler. (Multiple sclerosis (Houndmills, Basingstoke, England))
[2020, 26(2):257-258]

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Usefulness of MOG-antibody titres at first episode to predict the future clinical course in adults.

Alvaro Cobo-Calvo, María Sepúlveda, Hyacintha d'Indy, Thais Armangué, Anne Ruiz, Elisabeth Maillart, Caroline Papeix, Bertrand Audoin, Helene Zephir, Damien Biotti, Jonathan Ciron, Francoise Durand-Dubief, Nicolas Collongues, Xavier Ayrignac, Pierre Labauge, Eric Thouvenot, Alexis Montcuquet, Romain Deschamps, Nuria Solà-Valls, Sara Llufriu, Yolanda Blanco, Jerome de Seze, Sandra Vukusic, Albert Saiz, Romain Marignier, , ,

OBJECTIVE:To analyze whether myelin oligodendrocyte glycoprotein antibody (MOG-Ab) titres at onset of the disease were different according to the clinical phenotype at presentation, and to investigate whether the titres were associated with risk of further relapses or predicted clinical outcome in adult patients. Finally, we assessed an alternative method to ... Read more >>

J. Neurol. (Journal of neurology)
[2019, 266(4):806-815]

Cited: 3 times

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Making a 'JUMP' from paediatric to adult healthcare: A transitional program for young adults with chronic neurological disease.

Eavan Mary Mc Govern, Elisabeth Maillart, Marine Bourgninaud, Elodie Manzato, Cécile Guillonnet, Fanny Mochel, Julie Bourmaleau, Catherine Lubetzki, Michel Baulac, Emmanuel Roze,

BACKGROUND:"JUMP" is a multidisciplinary program based at the Pitie-Salpêtrière Hospital Paris that transitions young adults with chronic neurological conditions from paediatric to adult healthcare. Transitional care programs have been shown to improve medical, educational and psychosocial outcomes for adolescent patients. METHODS:Demographic details and health-related variables of all patients referred to ... Read more >>

J. Neurol. Sci. (Journal of the neurological sciences)
[2018, 395:77-83]

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Efficacy of rituximab in refractory RRMS.

Pierre Durozard, Adil Maarouf, Clémence Boutiere, Aurelie Ruet, Bruno Brochet, Sandra Vukusic, Clarisse Carra-Dalliere, Pierre Labauge, Guillaume Mathey, Marc Debouverie, Caroline Papeix, Elisabeth Maillart, Catherine Lubetzki, Caroline Bensa, Olivier Gout, Claire Giannesini, Bruno Stankoff, Jonathan Ciron, David Brassat, Jean Pelletier, Audrey Rico Lamy, Bertrand Audoin,

OBJECTIVE:To investigate the efficacy of rituximab as rescue therapy in patients with relapsing-remitting multiple sclerosis (RRMS) and persistent disease activity confirmed by magnetic resonance imaging (MRI) despite immunosuppressive disease-modifying therapy (DMT). METHODS:In this observational nationwide retrospective multicenter study, we first identified 351 off-label rituximab-treated patients through a cohort of 15,984 ... Read more >>

Mult. Scler. (Multiple sclerosis (Houndmills, Basingstoke, England))
[2019, 25(6):828-836]

Cited: 2 times

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Clinical spectrum and prognostic value of CNS MOG autoimmunity in adults: The MOGADOR study.

Alvaro Cobo-Calvo, Anne Ruiz, Elisabeth Maillart, Bertrand Audoin, Helene Zephir, Bertrand Bourre, Jonathan Ciron, Nicolas Collongues, David Brassat, Francois Cotton, Caroline Papeix, Francoise Durand-Dubief, David Laplaud, Romain Deschamps, Mikaël Cohen, Damien Biotti, Xavier Ayrignac, Caroline Tilikete, Eric Thouvenot, Bruno Brochet, Cecile Dulau, Thibault Moreau, Ayman Tourbah, Pierre Lebranchu, Laure Michel, Christine Lebrun-Frenay, Alexis Montcuquet, Guillaume Mathey, Marc Debouverie, Jean Pelletier, Pierre Labauge, Nathalie Derache, Marc Coustans, Fabien Rollot, Jérôme De Seze, Sandra Vukusic, Romain Marignier, ,

OBJECTIVE:To describe clinical and radiologic features associated with myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) in a large French nationwide adult cohort, to assess baseline prognostic features of MOG-Ab-associated diseases after a first acute demyelinating syndrome, and to evaluate the clinical value of MOG-Ab longitudinal analysis. METHODS:Clinical data were obtained from 197 ... Read more >>

Neurology (Neurology)
[2018, 90(21):e1858-e1869]

Cited: 23 times

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Early relapse after RTX initiation in a patient with NMO/MS overlap syndrome: How long to conclude to a failure treatment?

Elisabeth Maillart, Anaïs Lippi, Catherine Lubetzki, Céline Louapre, Caroline Papeix,

We report a dramatic clinical and radiological worsening within two months after rituximab initiation in a patient with NeuroMyelitis Optica/Multiple Sclerosis (NMO/MS) overlap syndrome.Case study.A 45-year-old Caucasian woman with NMO/MS overlap syndrome experienced a severe myelitis nine weeks after first rituximab infusion, with extensive new gadolinium-enhanced spinal cord lesions.This case ... Read more >>

Mult Scler Relat Disord (Multiple sclerosis and related disorders)
[2018, 20:220-222]

Cited: 0 times

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Multiple sclerosis and aging.

Céline Louapre, Caroline Papeix, Catherine Lubetzki, Elisabeth Maillart,

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system, whose incidental peak occurs around 30 years. This review focuses on epidemiologic, physiopathological, clinical and therapeutic characteristics of MS in elderly patients in two different situations: 1) late-onset MS (after 50 years), 2) aging in MS with ... Read more >>

Geriatr Psychol Neuropsychiatr Vieil (Geriatrie et psychologie neuropsychiatrie du vieillissement)
[2017, 15(4):402-408]

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Fast multiple sclerosis progression in North Africans: Both genetics and environment matter.

Youssef Sidhom, Elisabeth Maillart, Sophie Tezenas du Montcel, Imen Kacem, Catherine Lubetzki, Riadh Gouider, Caroline Papeix,

OBJECTIVE:To compare multiple sclerosis (MS) disability progression among North Africans (NAs) living in France (NAF) and in Tunisia (NAT) and Caucasian patients born and living in France (CF). METHODS:Patients with MS admitted to the day hospital in the Neurology Department at Pitié-Salpêtrière Hospital (France) and Razi Hospital (Tunisia) were questioned ... Read more >>

Neurology (Neurology)
[2017, 88(13):1218-1225]

Cited: 2 times

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Efficacy and Safety of Fingolimod in Daily Practice: Experience of an Academic MS French Center.

Thomas Roux, Elisabeth Maillart, Jean-Sébastien Vidal, Sophie Tezenas du Montcel, Catherine Lubetzki, Caroline Papeix,

Fingolimod (Fg), a sphingosine 1-phosphate receptor modulator, decreases the annual relapse rate (ARR) in relapsing-remitting multiple sclerosis (RRMS). The aim of this study was to assess the efficacy and safety of Fg in daily practice in patients with RRMS, previously treated with natalizumab (Nz) or not, and systematically followed during ... Read more >>

Front Neurol (Frontiers in neurology)
[2017, 8:183]

Cited: 1 time

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Disruption of the leptomeningeal blood barrier in neuromyelitis optica spectrum disorder.

Nasrin Asgari, Eoin P Flanagan, Kazuo Fujihara, Ho Jin Kim, Hanne P Skejoe, Jens Wuerfel, Hiroshi Kuroda, Su Hyun Kim, Elisabeth Maillart, Romain Marignier, Sean J Pittock, Friedemann Paul, Brian G Weinshenker,

To describe leptomeningeal blood-barrier impairment reflected by MRI gadolinium-enhanced lesions in patients with aquaporin-4 immunoglobulin G (AQP4-IgG)-positive neuromyelitis optica spectrum disorder (NMOSD).A retrospective case series of 11 AQP4-IgG-positive NMOSD patients with leptomeningeal enhancement (LME) were collected from 5 centers. External neuroradiologists, blinded to the clinical details, evaluated MRIs.LME was demonstrated ... Read more >>

Neurol Neuroimmunol Neuroinflamm (Neurology(R) neuroimmunology & neuroinflammation)
[2017, 4(4):e343]

Cited: 13 times

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Fatigue evaluation in fingolimod treated patients: An observational study.

Marion Masingue, Rabab Debs, Elisabeth Maillart, Valérie Delvaux, Catherine Lubetzki, Jean-Sébastien Vidal, Caroline Papeix,

Fatigue is one of the most disabling symptoms in Multiple Sclerosis (MS) patients and is associated with a low quality of life. Fingolimod (Fg), a sphingosine 1-phosphate receptor modulator, is the first oral MS disease modifying treatment. Little is known about its effect on fatigue. To assess the impact of ... Read more >>

Mult Scler Relat Disord (Multiple sclerosis and related disorders)
[2017, 14:8-11]

Cited: 2 times

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