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Author Eero Mattila

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Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements.

Juha Rannikko, Ville Holmberg, Matti Karppelin, Pertti Arvola, Reetta Huttunen, Eero Mattila, Niina Kerttula, Teija Puhto, Ülle Tamm, Irma Koivula, Risto Vuento, Jaana Syrjänen, Ulla Hohenthal,

Emerg Infect Dis (Emerging infectious diseases)
[2021, 27(8):]

Cited: 0 times

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Letter: faecal microbiota transplantation for irritable bowel syndrome-which improvements are required? Authors' reply.

Lahtinen Perttu, Jalanka Jonna, Hartikainen Anna, Mattila Eero, Hillilä Markku, Punkkinen Jari, Koskenpato Jari, Anttila Veli-Jukka, Tillonen Jyrki, Satokari Reetta, Arkkila Perttu,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2020, 52(11-12):1754-1755]

Cited: 0 times

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Letter: faecal microbiota transplantation for irritable bowel syndrome-room for improvement. Authors' reply.

Perttu Lahtinen, Jonna Jalanka, Anna Hartikainen, Eero Mattila, Markku Hillilä, Jari Punkkinen, Jari Koskenpato, Veli-Jukka Anttila, Jyrki Tillonen, Reetta Satokari, Perttu Arkkila,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2020, 52(5):925-926]

Cited: 0 times

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Letter: faecal microbiota transplantation for irritable bowel syndrome. Authors' reply.

Perttu Lahtinen, Jonna Jalanka, Anna Hartikainen, Eero Mattila, Markku Hillilä, Jari Punkkinen, Jari Koskenpato, Veli-Jukka Anttila, Jyrki Tillonen, Reetta Satokari, Perttu Arkkila,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2020, 52(3):557-558]

Cited: 0 times

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Cultivation and Genomics Prove Long-Term Colonization of Donor's Bifidobacteria in Recurrent Clostridioides difficile Patients Treated With Fecal Microbiota Transplantation.

Hanne Jouhten, Aki Ronkainen, Juhani Aakko, Seppo Salminen, Eero Mattila, Perttu Arkkila, Reetta Satokari,

Fecal microbiota transplantation (FMT) is an effective treatment for recurrent <i>Clostridioides difficile</i> infection (rCDI) and it's also considered for treating other indications. Metagenomic studies have indicated that commensal donor bacteria may colonize FMT recipients, but cultivation has not been employed to verify strain-level colonization. We combined molecular profiling of <i>Bifidobacterium</i> ... Read more >>

Front Microbiol (Frontiers in microbiology)
[2020, 11:1663]

Cited: 1 time

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Faecal banking at -20 °C facilitates faecal microbiota transplantation for recurrent Clostridioides difficile infection in clinical practice.

Reetta Satokari, Lotta Pietilä, Eero Mattila, Perttu Lahtinen, Perttu E T Arkkila,

Infect Dis (Lond) (Infectious diseases (London, England))
[2020, 52(9):662-665]

Cited: 0 times

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Randomised clinical trial: faecal microbiota transplantation versus autologous placebo administered via colonoscopy in irritable bowel syndrome.

Perttu Lahtinen, Jonna Jalanka, Anna Hartikainen, Eero Mattila, Markku Hillilä, Jari Punkkinen, Jari Koskenpato, Veli-Jukka Anttila, Jyrki Tillonen, Reetta Satokari, Perttu Arkkila,

BACKGROUND:Irritable bowel syndrome (IBS) has been associated with microbial dysbiosis. AIM:To investigate the efficacy of faecal microbiota transplantation (FMT) in the treatment of IBS. METHODS:Forty-nine IBS patients were randomised to receive autologous or allogenic FMT via colonoscopy. The primary endpoint was a sustained, minimum of 50-point, reduction in the IBS ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2020, 51(12):1321-1331]

Cited: 7 times

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Treatment of Clostridioides (Clostridium) difficile infection.

Jarmo Oksi, Veli-Jukka Anttila, Eero Mattila,

<i>Clostridioides</i> (formerly: <i>Clostridium</i>) <i>difficile</i> infection (CDI) is a major cause of diarrhoea for inpatients as well as outpatients. Usually, CDI is healthcare-associated but the number of community-acquired infections is increasing. CDI is generally associated with changes in the normal intestinal microbiota caused by administration of antibiotics. Elderly and immunocompromised patients ... Read more >>

Ann Med (Annals of medicine)
[2020, 52(1-2):12-20]

Cited: 0 times

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Minor Effect of Antibiotic Pre-treatment on the Engraftment of Donor Microbiota in Fecal Transplantation in Mice.

Tobias L Freitag, Anna Hartikainen, Hanne Jouhten, Cecilia Sahl, Seppo Meri, Veli-Jukka Anttila, Eero Mattila, Perttu Arkkila, Jonna Jalanka, Reetta Satokari,

Fecal microbiota transplantation (FMT) is an effective therapy for recurrent Clostridioides difficile infection (rCDI) and is also considered a potential treatment for a wide range of intestinal and systemic diseases. FMT corrects the microbial dysbiosis associated with rCDI, and the engraftment of donor microbiota is likely to play a key ... Read more >>

Front Microbiol (Frontiers in microbiology)
[2019, 10:2685]

Cited: 5 times

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Unexpectedly High Prevalence of Common Variable Immunodeficiency in Finland.

Jannica S Selenius, Timi Martelius, Sampsa Pikkarainen, Sanna Siitonen, Eero Mattila, Risto Pietikäinen, Pekka Suomalainen, Arja H Aalto, Janna Saarela, Elisabet Einarsdottir, Asko Järvinen, Martti Färkkilä, Juha Kere, Mikko Seppänen,

<h4>Background</h4>Common variable immunodeficiency (CVID) is the most common primary immunodeficiency. Prevalence varies greatly between countries and studies. Most diagnostic criteria include hypogammaglobulinemia and impaired vaccine response.<h4>Aim</h4>To evaluate the minimum prevalence as well as the clinical and immunological phenotypes of CVID in Southern Finland.<h4>Methods</h4>We performed a cross-sectional study to assess all ... Read more >>

Front Immunol (Frontiers in immunology)
[2017, 8:1190]

Cited: 17 times

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European consensus conference on faecal microbiota transplantation in clinical practice.

Giovanni Cammarota, Gianluca Ianiro, Herbert Tilg, Mirjana Rajilić-Stojanović, Patrizia Kump, Reetta Satokari, Harry Sokol, Perttu Arkkila, Cristina Pintus, Ailsa Hart, Jonathan Segal, Marina Aloi, Luca Masucci, Antonio Molinaro, Franco Scaldaferri, Giovanni Gasbarrini, Antonio Lopez-Sanroman, Alexander Link, Pieter de Groot, Willem M de Vos, Christoph Högenauer, Peter Malfertheiner, Eero Mattila, Tomica Milosavljević, Max Nieuwdorp, Maurizio Sanguinetti, Magnus Simren, Antonio Gasbarrini, ,

Faecal microbiota transplantation (FMT) is an important therapeutic option for <i>Clostridium difficile</i> infection. Promising findings suggest that FMT may play a role also in the management of other disorders associated with the alteration of gut microbiota. Although the health community is assessing FMT with renewed interest and patients are becoming ... Read more >>

Gut (Gut)
[2017, 66(4):569-580]

Cited: 210 times

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Reduction of Antibiotic Resistance Genes in Intestinal Microbiota of Patients With Recurrent Clostridium difficile Infection After Fecal Microbiota Transplantation.

Hanne Jouhten, Eero Mattila, Perttu Arkkila, Reetta Satokari,

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2016, 63(5):710-711]

Cited: 22 times

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Long-term effects on luminal and mucosal microbiota and commonly acquired taxa in faecal microbiota transplantation for recurrent Clostridium difficile infection.

Jonna Jalanka, Eero Mattila, Hanne Jouhten, Jorn Hartman, Willem M de Vos, Perttu Arkkila, Reetta Satokari,

<h4>Background</h4>Faecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection (rCDI). It restores the disrupted intestinal microbiota and subsequently suppresses C. difficile. The long-term stability of the intestinal microbiota and the recovery of mucosal microbiota, both of which have not been previously studied, are assessed herein. Further, ... Read more >>

BMC Med (BMC medicine)
[2016, 14(1):155]

Cited: 37 times

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Fecal transplantation treatment of antibiotic-induced, noninfectious colitis and long-term microbiota follow-up.

Reetta Satokari, Susana Fuentes, Eero Mattila, Jonna Jalanka, Willem M de Vos, Perttu Arkkila,

Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection (CDI) and is considered as a treatment for other gastrointestinal (GI) diseases. We followed up the relief of symptoms and long-term, over-a-year microbiota stabilization in a 46-year-old man, who underwent FMT for antibiotic-induced, non-CDI colitis nine months ... Read more >>

Case Rep Med (Case reports in medicine)
[2014, 2014:913867]

Cited: 18 times

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Extraintestinal Clostridium difficile infections.

Eero Mattila, Perttu Arkkila, Petri S Mattila, Eveliina Tarkka, Päivi Tissari, Veli-Jukka Anttila,

<h4>Background</h4> Clostridium difficile causes diarrhea that ranges from a benign, self-limiting antibiotic use-associated disease to a life-threatening pseudomembranous colitis. Clostridium difficile has rarely been isolated in extraintestinal infections. Our objective was to characterize clinical features and risk factors of these infections. METHODS Extraintestinal C. difficile infections (CDIs) were searched for in ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2013, 57(6):e148-53]

Cited: 25 times

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[Fecal transfusion as treatment of Clostridium difficile infection].

Perttu Arkkila, Eero Mattila, Veli-Jukka Anttila,

Clostridium difficile is the major identified cause of antibiotic-associated diarrhea. Metronidazole has been applied as the first-line treatment, while vancomycin has been used in recurring cases of the disease. Fecal transfusion has already long been applied as experimental therapy in the treatment of recurring C. difficile infection. The aim of ... Read more >>

Duodecim (Duodecim; laaketieteellinen aikakauskirja)
[2013, 129(16):1671-1679]

Cited: 1 time

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Fecal transplantation, through colonoscopy, is effective therapy for recurrent Clostridium difficile infection.

Eero Mattila, Raija Uusitalo-Seppälä, Maarit Wuorela, Laura Lehtola, Heimo Nurmi, Matti Ristikankare, Veikko Moilanen, Kimmo Salminen, Maaria Seppälä, Petri S Mattila, Veli-Jukka Anttila, Perttu Arkkila,

<h4>Background & aims</h4>Treatment of recurrent Clostridium difficile infection (CDI) with antibiotics leads to recurrences in up to 50% of patients. We investigated the efficacy of fecal transplantation in treatment of recurrent CDI.<h4>Methods</h4>We reviewed records from 70 patients with recurrent CDI who had undergone fecal transplantation. Fecal transplantation was performed at ... Read more >>

Gastroenterology (Gastroenterology)
[2012, 142(3):490-496]

Cited: 174 times

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A randomized, double-blind study comparing Clostridium difficile immune whey and metronidazole for recurrent Clostridium difficile-associated diarrhoea: efficacy and safety data of a prematurely interrupted trial.

Eero Mattila, Veli-Jukka Anttila, Markku Broas, Harri Marttila, Paula Poukka, Kaisa Kuusisto, Liana Pusa, Kari Sammalkorpi, Jan Dabek, Olli-Pekka Koivurova, Markku Vähätalo, Veikko Moilanen, Tom Widenius,

A prospective, randomized, double-blind study was designed to compare Clostridium difficile immune whey (CDIW) with metronidazole for treatment of laboratory-confirmed, recurrent, mild to moderate episodes of Clostridium difficile-associated diarrhoea (CDAD). CDIW was manufactured by immunization of cows in their gestation period with inactivated C. difficile vaccine. The resulting colostrum was ... Read more >>

Scand J Infect Dis (Scandinavian journal of infectious diseases)
[2008, 40(9):702-708]

Cited: 43 times

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Acute heart failure: clinical presentation, one-year mortality and prognostic factors.

Alain Rudiger, Veli-Pekka Harjola, Andreas Müller, Eero Mattila, Petrus Säila, Markku Nieminen, Ferenc Follath,

<h4>Aims</h4>Acute heart failure (HF) is a common but ill-defined clinical entity. We describe patients hospitalised with acute HF in regard of clinical presentation, mortality, and risk factors for an unfavourable outcome.<h4>Methods and results</h4>We conducted a prospective study including 312 consecutive patients from two European centers hospitalised with acute HF, defined ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2005, 7(4):662-670]

Cited: 81 times

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