Full Text Journal Articles by
Author Edward P Walsh

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Lead age as a predictor for failure in pediatrics and congenital heart disease.

Robert D Whitehill, Stephanie F Chandler, Elizabeth DeWitt, Dominic J Abrams, Edward P Walsh, Michael Kelleman, Douglas Y Mah,

<h4>Background</h4>Pediatric and congenital heart disease (CHD) patients have a high rate of transvenous (TV) lead failure.<h4>Objective</h4>To determine whether TV lead age can aid risk assessment for lead failure to guide the decision of whether a lead should be replaced or reused at time of generator change.<h4>Methods</h4>Retrospective cohort study of patients ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2021, :]

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Difference in the prevalence of intracardiac thrombus on the first presentation of atrial fibrillation versus flutter in the pediatric and congenital heart disease population.

Omar Meziab, Luciana Marcondes, Kevin G Friedman, Edward T O'Leary, Michelle Gurvitz, Christina J VanderPluym, Edward P Walsh, John K Triedman, Douglas Y Mah,

<h4>Introduction</h4>Guidelines recommend trans-esophageal echocardiography (TEE) for patients with atrial fibrillation (AF) or atrial flutter (AFL) for >48 h, due to risk of intracardiac thrombus formation. With growing evidence that AFL in adults with structurally normal hearts has less thrombogenic potential compared to AF, and the need for TEE questioned, we compared ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2020, 31(12):3243-3250]

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Corrigendum to ' Ventricular Arrhythmia and Life-Threatening Events in Patients With Repaired Tetralogy of Fallot' [The American Journal of Cardiology 132 (2020) 126-132].

Joseph Atallah, M Cecilia Gonzalez Corcia, Edward P Walsh, ,

Am J Cardiol (The American journal of cardiology)
[2021, 138:133]

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Risk Factors for Early Recurrence Following Ablation for Accessory Pathways: The Role of Consolidation Lesions.

Audrey Dionne, Kimberlee Gauvreau, Edward O'Leary, Douglas Y Mah, Dominic J Abrams, Mark E Alexander, Elizabeth S DeWitt, Vassilios J Bezzerides, John K Triedman, Edward P Walsh,

<h4>Background</h4>Atrioventricular reentrant tachycardia is common in children. Catheter ablation is increasingly used as a first-line therapy with a high acute success rate, but recurrence during follow-up remains a concern. The aim of this study was to identify risk factors for recurrence after accessory pathway (AP) ablation.<h4>Methods</h4>Retrospective cohort study including patients ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2020, 13(11):e008848]

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Ventricular Arrhythmia and Life-Threatening Events in Patients With Repaired Tetralogy of Fallot.

Joseph Atallah, M Cecilia Gonzalez Corcia, Edward P Walsh, ,

Risk stratification for malignant arrhythmias and risk of sudden cardiac death in tetralogy of Fallot (TOF) remains challenging. We aimed to ascertain factors associated with life-threatening arrhythmic events. A multicenter retrospective case-control study including 72 TOF patients with documented cardiac arrest and/or sustained ventricular tachycardia, compared with 216 controls matched ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2020, 132:126-132]

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Value of provocative electrophysiology testing in the management of pediatric patients after congenital heart surgery.

Audrey Dionne, John N Kheir, Kimberlee Gauvreau, John K Triedman, Dominic J Abrams, Mark E Alexander, Elizabeth S DeWitt, Douglas Y Mah, Edward P Walsh, Vassilios J Bezzerides,

<h4>Objective</h4>To determine the impact of provocative electrophysiology testing in postoperative congenital heart disease (CHD) patients on the management of supraventricular tachycardia (SVT) and clinical outcomes.<h4>Methods</h4>This is a retrospective study including patients <18 years of age with surgery for CHD who had postoperative SVT between 2006 and 2017. Postoperative outcomes were compared ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2020, 43(9):901-907]

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Adverse event rate during inpatient sotalol initiation for the management of supraventricular and ventricular tachycardia in the pediatric and young adult population.

Stephanie F Chandler, Esther Chu, Robert D Whitehill, Laura M Bevilacqua, Vassilios J Bezzerides, Elizabeth S DeWitt, Mark E Alexander, Dominic J Abrams, John K Triedman, Edward P Walsh, Douglas Y Mah,

<h4>Background</h4>Sotalol is an important antiarrhythmic drug in the pediatric population. Given the risk of proarrhythmia, sotalol is initiated in inpatient settings, with adult studies as recent as 2015 supporting this practice.<h4>Objective</h4>The purpose of this study was to determine the frequency of adverse events (AEs) during sotalol initiation for the management ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, 17(6):984-990]

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Examination of pathologic features of the right atrioventricular groove in hearts with Ebstein anomaly and correlation with arrhythmias.

Luciana Marcondes, Stephen P Sanders, Pedro J Del Nido, Edward P Walsh,

BACKGROUND:Catheter ablation of accessory pathways (APs) in patients with Ebstein anomaly (EA) has a higher recurrence rate than in subjects with normal hearts. Anatomic features could account for suboptimal ablation outcomes. OBJECTIVE:The purpose of this study was to examine the right atrioventricular (AV) groove in autopsy hearts with EA, correlate ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, 17(7):1092-1098]

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Outcomes of catheter ablation of anteroseptal and midseptal accessory pathways in pediatric patients.

Joshua R Kovach, Douglas Y Mah, Dominic J Abrams, Mark E Alexander, Frank Cecchin, John K Triedman, Edward P Walsh,

<h4>Background</h4>Outcomes for catheter ablation of accessory pathways in pediatric patients have steadily improved, with the exception of pathways located in the anteroseptal (AS) and midseptal (MS) regions, where success is limited by the close proximity of normal atrioventricular conduction.<h4>Objective</h4>The purpose of this study was to evaluate the efficacy of different ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, 17(5 Pt A):759-767]

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Arrhythmia Mechanisms and Outcomes of Ablation in Pediatric Patients With Congenital Heart Disease.

Charlotte A Houck, Stephanie F Chandler, Ad J J C Bogers, John K Triedman, Edward P Walsh, Natasja M S de Groot, Dominic J Abrams,

BACKGROUND:In contrast to the adult population with congenital heart disease (CHD), arrhythmia mechanisms and outcomes of ablation in pediatric patients with CHD in recent era have not been studied in detail. Aims of this study were to determine arrhythmia mechanisms and to evaluate procedural and long-term outcomes in pediatric patients ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2019, 12(11):e007663]

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Long-term results of atrial maze surgery in patients with congenital heart disease.

M Cecilia Gonzalez Corcia, Edward P Walsh, Sitaram Emani,

<h4>Aims</h4>Recurrent atrial tachycardia is common after repair of many types of congenital heart disease, and surgical ablation with a maze procedure represents a potential treatment strategy. The objective of this study is to report a single-centre 19 years' experience with maze surgery in congenital heart patients.<h4>Methods and results</h4>Patients undergoing maze ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2019, 21(9):1345-1352]

Cited: 1 time

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Interdigitating Myocardial Tongues in Pediatric Cardiac Fibromas: Plausible Substrate for Ventricular Tachycardia and Cardiac Arrest.

Chrystalle Katte Carreon, Stephen P Sanders, Antonio R Perez-Atayde, Pedro J Del Nido, Edward P Walsh, Tal Geva, Mark E Alexander,

<h4>Objectives</h4>This study sought to evaluate for the presence of and characterize the interdigitating and entrapped myocardium within cardiac fibromas (CF) and correlate tissue findings with symptoms and surgical outcomes.<h4>Background</h4>The mechanism of ventricular tachycardia (VT) in CF is unclear. The authors hypothesized that CF harbor tongues of interdigitating myocardium, which could ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2019, 5(5):563-575]

Cited: 1 time

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Differentiation of fasciculoventricular fibers from anteroseptal accessory pathways using the surface electrocardiogram.

Edward T O'Leary, Elizabeth S Dewitt, Douglas Y Mah, Kimberlee Gauvreau, Edward P Walsh, Vassilios J Bezzerides,

<h4>Background</h4>Fasciculoventricular fibers (FVFs) are responsible for 1%-5% of cases of asymptomatic preexcitation on the surface electrocardiogram (ECG). Unlike ventricular preexcitation seen in Wolff-Parkinson-White (WPW) syndrome, FVFs are not associated with sudden cardiac death from preexcited atrial fibrillation.<h4>Objective</h4>The purpose of this study was to identify surface ECG variables that differentiate FVFs ... Read more >>

Heart Rhythm (Heart rhythm)
[2019, 16(7):1072-1079]

Cited: 4 times

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Evaluation of left ventricular false tendons in children with idiopathic left ventricular tachycardia.

Anthony Merlocco, David W Brown, Kimberlee Gauvreau, Douglas Y Mah, John K Triedman, Mark E Alexander, Edward P Walsh,

<h4>Background</h4>Left ventricular false tendons (FT) traverse the ventricular cavity and are thought to have some association with idiopathic left ventricular tachycardia (ILVT). However, reported prevalence of FT varies widely, making correlation difficult. Superior echocardiographic windows of pediatric patients may permit better analysis of FT in ILVT. Our study describes the ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2018, 41(9):1143-1149]

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Dual-Site Ventricular Pacing in Patients With Fontan Physiology and Heart Block: Does it Mitigate the Detrimental Effects of Single-Site Ventricular Pacing?

Edward T O'Leary, Kimberlee Gauvreau, Mark E Alexander, Puja Banka, Vassilios J Bezzerides, Francis Fynn-Thompson, John K Triedman, Edward P Walsh, Douglas Y Mah,

<h4>Objectives</h4>This study sought to determine the long-term effect of dual-site ventricular pacing (i.e., cardiac resynchronization therapy [CRT]) versus single-site pacing in patients with Fontan physiology and high-grade atrioventricular block (AVB).<h4>Background</h4>Chronic single-site ventricular pacing in Fontan patients is associated with significant morbidity and mortality.<h4>Methods</h4>The study conducted a retrospective review of all ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2018, 4(10):1289-1297]

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Catheter Ablation of Ventricular Arrhythmia for Ebstein's Anomaly in Unoperated and Post-Surgical Patients.

Jeremy P Moore, Kevin M Shannon, Roberto G Gallotti, Christopher J McLeod, Anca Chiriac, Edward P Walsh, Narayanswami Sreeram, Akash R Patel, Natasja M De Groot, Johannes von Alvensleben, Seshadri Balaji, David S Frankel, Christina Y Miyake, James C Perry, Kalyanam Shivkumar,

<h4>Objectives</h4>The purpose of this study was to determine the ventricular arrhythmia (VA) substrates in patients with unoperated and post-surgical Ebstein's Anomaly (EA).<h4>Background</h4>EA is associated with variable atrialization of the right ventricle and a propensity for VA and sudden death. There are scant data on catheter ablation for VA in this ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2018, 4(10):1300-1307]

Cited: 2 times

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Ebstein's Anomaly of the Tricuspid Valve: A Natural Laboratory for Re-Entrant Tachycardias.

Edward P Walsh,

Ebstein's anomaly of the tricuspid valve is a relatively rare form of congenital heart disease that has long been a challenge to electrophysiologists and cardiac surgeons. In addition to the hemodynamic burden of the actual valve defect, Ebstein's patients must also contend with an extraordinarily high incidence of tachyarrhythmias, most ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2018, 4(10):1271-1288]

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Utility of incomplete right bundle branch block as an isolated ECG finding in children undergoing initial cardiac evaluation.

Omar Meziab, Dominic J Abrams, Mark E Alexander, Laura Bevilacqua, Vassilios Bezzerides, Doug Y Mah, Edward P Walsh, John K Triedman,

This study evaluates the ability of experienced pediatric electrophysiologists (EPs) to reliably classify incomplete right bundle branch block (IRBBB) and assesses its clinical utility as an isolated ECG finding in a group of healthy outpatient children without prior cardiac evaluation.We performed a retrospective analysis of all electrocardiographic and echocardiographic records ... Read more >>

Congenit Heart Dis (Congenital heart disease)
[2018, 13(3):419-427]

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The role of ablation therapy for ventricular tachycardia in patients with tetralogy of Fallot.

Edward P Walsh,

Heart Rhythm (Heart rhythm)
[2018, 15(5):686-687]

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Cardiac Events During Competitive, Recreational, and Daily Activities in Children and Adolescents With Long QT Syndrome.

Kristina D Chambers, Virginie Beausejour Ladouceur, Mark E Alexander, Robyn J Hylind, Laura Bevilacqua, Douglas Y Mah, Vassilios Bezzerides, John K Triedman, Edward P Walsh, Dominic J Abrams,

<h4>Background</h4>The 2005 Bethesda Conference Guidelines advise patients with long QT syndrome against competitive sports. We assessed cardiac event rates during competitive and recreational sports, and daily activities among treated long QT syndrome patients.<h4>Methods and results</h4>Long QT syndrome patients aged ≥4 years treated with anti-adrenergic therapy were included. Demographics included mechanism of ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2017, 6(9):]

Cited: 1 time

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Epicardial ablation of tachyarrhythmia in children: Experience at two academic centers.

Shailendra Upadhyay, Edward P Walsh, Frank Cecchin, John K Triedman, Juan Villafane, J Philip Saul,

<h4>Background</h4>Experience with percutaneous epicardial ablation of tachyarrhythmia in pediatrics is limited. This case series addresses the feasibility, safety, and complications of the procedure in children.<h4>Methods</h4>A total of nine patients underwent 10 epicardial ablation procedures from 2002 to 2013 at two academic centers. Activation mapping was performed in all cases, and ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2017, 40(9):1017-1026]

Cited: 1 time

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The Phenotypic Spectrum of a Mutation Hotspot Responsible for the Short QT Syndrome.

Dan Hu, Yang Li, Jiancheng Zhang, Ryan Pfeiffer, Michael H Gollob, Jeff Healey, Daniel Toshio Harrell, Naomasa Makita, Haruhiko Abe, Yaxun Sun, Jihong Guo, Li Zhang, Ganxin Yan, Douglas Mah, Edward P Walsh, Harris B Leopold, Carla Giustetto, Fiorenzo Gaita, Agnieszka Zienciuk-Krajka, Andrea Mazzanti, Silvia G Priori, Charles Antzelevitch, Hector Barajas-Martinez,

OBJECTIVES:This study sought to evaluate the phenotypic and functional expression of an apparent hotspot mutation associated with short QT syndrome (SQTS). BACKGROUND:SQTS is a rare channelopathy associated with a high risk of life-threatening arrhythmias and sudden cardiac death (SCD). METHODS:Probands diagnosed with SQTS and their family members were evaluated clinically ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2017, 3(7):727-743]

Cited: 8 times

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Improved understanding of ventricular Tachycardia in patients with tetralogy of Fallot.

Edward P Walsh,

Eur Heart J (European heart journal)
[2017, 38(4):277-279]

Cited: 0 times

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Catheter ablation for atrioventricular nodal reentrant tachycardia in patients with congenital heart disease.

Shailendra Upadhyay, Anne Marie Valente, John K Triedman, Edward P Walsh,

<h4>Background</h4>Variability in atrioventricular (AV) node location in congenital heart disease (CHD) can make catheter ablation for atrioventricular nodal reentrant tachycardia (AVNRT) challenging.<h4>Objective</h4>The purpose of this study was to describe institutional technique and outcomes for slow pathway modification in a cohort with CHD.<h4>Methods</h4>The study consisted of a retrospective review of CHD ... Read more >>

Heart Rhythm (Heart rhythm)
[2016, 13(6):1228-1237]

Cited: 6 times

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Task Force 4: Pediatric Cardiology Fellowship Training in Electrophysiology.

Anne M Dubin, Edward P Walsh, Wayne Franklin, Ronald J Kanter, J Philip Saul, Maully J Shah, George F Van Hare, Julie A Vincent,

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2015, 66(6):706-711]

Cited: 2 times

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