Full Text Journal Articles by
Author Edward P Gerstenfeld

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Atrioventricular Block With Narrow and Wide QRS: The Pause That Refreshes.

Satoshi Higuchi, Nora Goldschlager, Edward P Gerstenfeld,

Circulation (Circulation)
[2021, 144(15):1262-1264]

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Iatrogenic Atrioventricular Block.

Christopher C Cheung, Shumpei Mori, Edward P Gerstenfeld,

Iatrogenic atrioventricular (AV) block can occur in the context of cardiac surgery, percutaneous transcatheter, or electrophysiologic procedures. In cardiac surgery, patients undergoing aortic and/or mitral valve surgery are at the highest risk for developing perioperative AV block requiring permanent pacemaker implantation. Similarly, patients undergoing transcatheter aortic valve replacement are also ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, 13(4):711-720]

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Beware of the hazards: limitations of the proportional hazards assumption.

Christopher C Cheung, Eric Vittinghoff, Gregory M Marcus, Edward P Gerstenfeld,

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2021, :]

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Acute Consumption of Alcohol and Discrete Atrial Fibrillation Events.

Gregory M Marcus, Eric Vittinghoff, Isaac R Whitman, Sean Joyce, Vivian Yang, Gregory Nah, Edward P Gerstenfeld, Joshua D Moss, Randall J Lee, Byron K Lee, Zian H Tseng, Vasanth Vedantham, Jeffrey E Olgin, Melvin M Scheinman, Henry Hsia, Rachel Gladstone, Shannon Fan, Emily Lee, Christina Fang, Kelsey Ogomori, Robin Fatch, Judith A Hahn,

<h4>Background</h4>Patients' self-reports suggest that acute alcohol consumption may trigger a discrete atrial fibrillation (AF) event.<h4>Objective</h4>To objectively ascertain whether alcohol consumption heightens risk for an AF episode.<h4>Design</h4>A prospective, case-crossover analysis.<h4>Setting</h4>Ambulatory persons in their natural environments.<h4>Participants</h4>Consenting patients with paroxysmal AF.<h4>Measurements</h4>Participants were fitted with a continuous electrocardiogram (ECG) monitor and an ankle-worn transdermal ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2021, 174(11):1503-1509]

Cited: 1 time

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Misleading Placement of a Dual-Chamber Pacemaker.

David G Rosenthal, David Blusztein, Vaikom S Mahadevan, Edward P Gerstenfeld,

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, :]

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Atrial Tachycardia Ablation at the Pulmonic Valve in a Patient With Congenitally Corrected Transposition of Great Arteries.

Christopher C Cheung, Eunjeong Kim, Zian H Tseng, Edward P Gerstenfeld, Robert H Anderson, Damian Sanchez-Quintana, Eduardo Back Sternick, Henry H Hsia,

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, 7(11):1473-1481]

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Two P waves followed by 1 QRS complex: What is the mechanism?

Satoshi Higuchi, Sung Il Im, Edward P Gerstenfeld, Melvin M Scheinman,

Heart Rhythm (Heart rhythm)
[2021, 18(7):1243-1244]

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Predictors of long-term success after catheter ablation of premature ventricular complexes.

Sung-Il Im, Aleksandr Voskoboinik, Adam Lee, Satoshi Higuchi, Joshua D Moss, Henry Hsia, Zian H Tseng, Randall Lee, Gregory M Marcus, Vasanth Vedantham, Melvin Scheinman, Byron Lee, Kyoung-Min Park, Edward P Gerstenfeld,

<h4>Introduction</h4>Some patients have late recurrence after acutely successful radiofrequency catheter ablation (RFCA) of premature ventricular complexes (PVCs). The aim of this study was to evaluate predictors of long-term success following acutely successful PVC RFCA.<h4>Methods</h4>We identified consecutive patients at our institution with frequent PVCs undergoing RFCA and reviewed procedural data and ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2021, 32(8):2254-2261]

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Use of Adenosine to Release an Entrapped Catheter During Ablation of Premature Ventricular Complexes.

Eun-Jeong Kim, Edward P Gerstenfeld, Cara N Pellegrini,

Catheter entrapment is a rare complication during catheter ablation that may require surgical intervention. Use of adenosine to prolong diastole can be a safe and effective strategy to free the catheter and avoid significant morbidity. (<b>Level of Difficulty: Advanced.</b>). ... Read more >>

JACC Case Rep (JACC. Case reports)
[2021, 3(4):610-613]

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The Role of the Left Septal Fascicle in Fascicular Arrhythmias: Clinical Presentation and Laboratory Evaluation.

José M Sanchez, Satoshi Higuchi, Tomos E Walters, Vasanth Vedantham, Henry Hsia, Edward P Gerstenfeld, Nitish Badhwar, Mariana Albona, Mario Njeim, Melvin M Scheinman,

<h4>Objectives</h4>This study describes a series of cases best explained by invoking the left septal fascicle (LSF) as a critical component of the arrhythmia circuit.<h4>Background</h4>Numerous anatomic studies have shown evidence of the LSF, but its precise role in the onset of arrhythmia is unclear.<h4>Methods</h4>This paper presents 5 cases that implicated the ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, 7(7):858-870]

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A Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Alcohol to Assess Changes in Atrial Electrophysiology.

Gregory M Marcus, Jonathan W Dukes, Eric Vittinghoff, Gregory Nah, Nitish Badhwar, Joshua D Moss, Randall J Lee, Byron K Lee, Zian H Tseng, Tomos E Walters, Vasanth Vedantham, Rachel Gladstone, Shannon Fan, Emily Lee, Christina Fang, Kelsey Ogomori, Trisha Hue, Jeffrey E Olgin, Melvin M Scheinman, Henry Hsia, Vijay A Ramchandani, Edward P Gerstenfeld,

<h4>Objectives</h4>This study sought to identify acute changes in human atrial electrophysiology during alcohol exposure.<h4>Background</h4>The mechanism by which a discrete episode of atrial fibrillation (AF) occurs remains unknown. Alcohol appears to increase the risk for AF, providing an opportunity to study electrophysiologic effects that may render the heart prone to arrhythmia.<h4>Methods</h4>In ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, 7(5):662-670]

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High-intensity ultrasound catheter ablation achieves deep mid-myocardial lesions in vivo.

Babak Nazer, David Giraud, Yan Zhao, James Hodovan, Miriam R Elman, Ahmad Masri, Edward P Gerstenfeld, Jonathan R Lindner,

<h4>Background</h4>Radiofrequency ablation of epicardial and mid-myocardial ventricular arrhythmias is limited by lesion depth.<h4>Objective</h4>The purpose of this study was to generate deep mid-interventricular septal (IVS) lesions using high-intensity ultrasound (US) from an endocardial catheter-based approach.<h4>Methods</h4>Irrigated US catheters (12 F) were fabricated with 3 × 5 mm transducers of 5.0, 6.5, and ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(4):623-631]

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ECG quiz - Where is the block?

Christopher C Cheung, Edward P Gerstenfeld,

A 68 year-old man presented with palpitations. A standard 12‑lead ECG was performed and demonstrated significant conduction disease. Using findings on the index and prior ECGs, we review the differential diagnoses for his conduction abnormality. We discuss the possibility of phase III delay, phase IV delay, and "supernormal conduction" to explain ... Read more >>

J Electrocardiol (Journal of electrocardiology)
[2021, 64:42-44]

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Electrophysiologic approach to diagnosis and ablation of patients with permanent junctional reciprocating tachycardia associated with complex anatomy and/or physiology.

Adam Oesterle, Adam C Lee, Aleksandr Voskoboinik, Joshua D Moss, Vasanth Vedantham, Tomos E Walters, Byron K Lee, Zian H Tseng, Edward P Gerstenfeld, Melvin M Scheinman,

<h4>Introduction</h4>Permanent junctional reciprocating tachycardia (PJRT) is a rare supraventricular tachycardia (SVT), typically involving a single decremental posteroseptal accessory pathway (AP).<h4>Methods</h4>Four patients with long RP SVT underwent electrophysiology (EP) study and ablation. The cases were reviewed.<h4>Results</h4>Case 1 recurred despite 3 prior ablations at the site of earliest retrograde atrial activation during ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2020, 31(12):3232-3242]

Cited: 0 times

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Microbubble-Facilitated Ultrasound Catheter Ablation Causes Microvascular Damage and Fibrosis.

Babak Nazer, David Giraud, Yan Zhao, Yue Qi, O'Neil Mason, Peter D Jones, Chris J Diederich, Edward P Gerstenfeld, Jonathan R Lindner,

High-intensity ultrasound (US) ablation produces deeper myocardial lesions than radiofrequency ablation. The presence of intravascular microbubble (MB) contrast agents enhances pulsed-wave US ablation via cavitation-related histotripsy, potentially facilitating ablation in persistently perfused/conducting myocardium. US ablation catheters were developed and tested in the presence of MBs using ex vivo and in ... Read more >>

Ultrasound Med Biol (Ultrasound in medicine & biology)
[2021, 47(1):131-138]

Cited: 1 time

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Epsilon Wave Resolution Following Epicardial Ablation in Arrhythmogenic Right Ventricular Cardiomyopathy.

Adam Lee, Satoshi Higuchi, Edward P Gerstenfeld,

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(11):1470-1471]

Cited: 1 time

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Dyssynchrony and Fibrosis Persist After Resolution of Cardiomyopathy in a Swine Premature Ventricular Contraction Model.

Tomos E Walters, Judit Szilagyi, Christina Alhede, Richard Sievers, Qizhi Fang, Jeffrey Olgin, Edward P Gerstenfeld,

<h4>Objectives</h4>This study sought to prospectively study the development and then regression of premature ventricular contraction (PVC)-induced cardiomyopathy, with the hypothesis that structural left ventricular (LV) changes that are of potential clinical significance may endure beyond the period of exposure to PVCs.<h4>Background</h4>Recovery of LV function after eradication of PVCs in PVC-induced ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(11):1367-1376]

Cited: 1 time

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Complex Re-Entrant Arrhythmias Involving the His-Purkinje System: A Structured Approach to Diagnosis and Management.

Aleksandr Voskoboinik, Edward P Gerstenfeld, Joshua D Moss, Henry Hsia, Jeffrey Goldberger, Babak Nazer, Thomas Dewland, David Singh, Nitish Badhwar, Patrick J Tchou, John N Meriwether, William Sauer, Asaf Danon, Bernard Belhassen, Melvin M Scheinman,

<h4>Objectives</h4>This study sought to characterize the presentations, electrophysiological features and diagnostic maneuvers for a series of unique arrhythmias involving the HPS.<h4>Background</h4>By virtue of its unique anatomy and ion channel composition, the His-Purkinje system (HPS) is prone to a variety of arrhythmic perturbations.<h4>Methods</h4>The authors present a collaborative multicenter case series of ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(12):1488-1498]

Cited: 0 times

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Site-Specific Epicardium-to-Endocardium Dissociation of Electrical Activation in a Swine Model of Atrial Fibrillation.

Tomos E Walters, Geoffrey Lee, Adam Lee, Richard Sievers, Jonathan M Kalman, Edward P Gerstenfeld,

<h4>Objectives</h4>This study sought to define the extent and spatial distribution of endocardial-epicardial dissociation (EED) in a swine model.<h4>Background</h4>The mechanisms underlying persistent atrial fibrillation (AF) remain unclear.<h4>Methods</h4>Sixteen swine underwent simultaneous endocardial and epicardial mapping using 32-electrode grid catheters. This included 6 swine with rapid atrial pacing-induced atrial remodeling. Three right atrial ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(7):830-845]

Cited: 0 times

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Persistent Atrial Fibrillation Ablation: Strengthening the Evidence.

Edward P Gerstenfeld, Joshua D Moss,

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(8):970-972]

Cited: 0 times

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Endocardial-Epicardial Phase Mapping of Prolonged Persistent Atrial Fibrillation Recordings: High Prevalence of Dissociated Activation Patterns.

Ramanathan Parameswaran, Jonathan M Kalman, Alistair Royse, John Goldblatt, Marco Larobina, Troy Watts, Tomos E Walters, Chrishan J Nalliah, Geoffrey Wong, Ahmed Al-Kaisey, Robert Douglas Anderson, Aleksandr Voskoboinik, Hariharan Sugumar, David Chieng, Prashanthan Sanders, Peter M Kistler, Edward P Gerstenfeld, Geoffrey Lee,

BACKGROUND:Endocardial-epicardial dissociation and focal breakthroughs in humans with atrial fibrillation (AF) have been recently demonstrated using activation mapping of short 10-second AF segments. In the current study, we used simultaneous endo-epi phase mapping to characterize endo-epi activation patterns on long segments of human persistent AF. METHODS:Simultaneous intraoperative mapping of endo- ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2020, 13(8):e008512]

Cited: 3 times

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Long-term outcomes of ablation for ventricular arrhythmias in mitral valve prolapse.

Paul J Marano, Lisa J Lim, Jose M Sanchez, Raza Alvi, Gregory Nah, Nitish Badhwar, Edward P Gerstenfeld, Zian H Tseng, Gregory M Marcus, Francesca N Delling,

<h4>Purpose</h4>Prior studies reporting efficacy of radiofrequency catheter ablation for complex ventricular ectopy in mitral valve prolapse (MVP) are limited by selective inclusion of bileaflet MVP, papillary muscle only ablation, or short-term follow-up. We sought to evaluate the long-term incidence of hemodynamically significant ventricular tachycardia (VT) or fibrillation (VF) in patients ... Read more >>

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2021, 61(1):145-154]

Cited: 1 time

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Approach to recurrent atrial fibrillation with isolated pulmonary veins.

Edward P Gerstenfeld,

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2020, 31(7):1872-1873]

Cited: 0 times

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Direct Thrombin Inhibitors as an Alternative to Heparin During Catheter Ablation: A Multicenter Experience.

Aleksandr Voskoboinik, Eric Butcher, Amneet Sandhu, Duy T Nguyen, Wendy Tzou, Domenico G Della Rocca, Andrea Natale, Erica S Zado, Francis E Marchlinski, Martin Aguilar, William Sauer, Usha B Tedrow, Edward P Gerstenfeld,

<h4>Objectives</h4>The goal of this study was to report a multicenter series of left-sided catheter ablations performed by using intravenous direct thrombin inhibitors (DTIs) as an alternative to heparin.<h4>Background</h4>Amidst a looming worldwide shortage of heparin, there are insufficient data to guide nonheparin-based peri-procedural anticoagulation in patients undergoing catheter ablation.<h4>Methods</h4>This study reviewed ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(5):484-490]

Cited: 0 times

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Noninvasive ventricular tachycardia ablation: Should we apply the accelerator or the brake?

Thomas A Dewland, Anthony C Wong, Edward P Gerstenfeld,

Heart Rhythm (Heart rhythm)
[2020, 17(8):1249-1250]

Cited: 1 time

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