Full Text Journal Articles by
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Suveer Singh, Diana A Gorog, Ciara F Mahon, Bhavin Rawal, Thomas R Semple, Edward D Nicol, Deepa R J Arachchillage, Susanna Price, Sujal Desai, Carole A Ridge, Simon P G Padley, Saeed Mirsadraee,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1190-e1191]

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Association of coronary artery calcium score with qualitatively and quantitatively assessed adverse plaque on coronary CT angiography in the SCOT-HEART trial.

Maia Osborne-Grinter, Jacek Kwiecinski, Mhairi Doris, Priscilla McElhinney, Sebastien Cadet, Philip D Adamson, Alastair J Moss, Shirjel Alam, Amanda Hunter, Anoop S V Shah, Nicholas L Mills, Tania Pawade, Chengjia Wang, Jonathan R Weir-McCall, Giles Roditi, Edwin J R van Beek, Leslee J Shaw, Edward D Nicol, Daniel Berman, Piotr J Slomka, David E Newby, Marc R Dweck, Damini Dey, Michelle C Williams,

<h4>Aims</h4>Coronary artery calcification is a marker of cardiovascular risk, but its association with qualitatively and quantitatively assessed plaque subtypes is unknown.<h4>Methods and results</h4>In this post-hoc analysis, computed tomography (CT) images and 5-year clinical outcomes were assessed in SCOT-HEART trial participants. Agatston coronary artery calcium score (CACS) was measured on non-contrast ... Read more >>

Eur Heart J Cardiovasc Imaging (European heart journal. Cardiovascular Imaging)
[2021, :]

Cited: 0 times

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The European Association of Preventive Cardiology Aviation and Occupational Cardiology Task Force.

Edward D Nicol, David A Holdsworth, Martin Halle, Constantinos H Davos,

Eur Heart J (European heart journal)
[2021, 42(21):2030-2033]

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Following the evidence: The pre-eminent role of coronary CT angiography in 2021.

Edward D Nicol, Gudrun M Feuchtner, Todd C Villines,

J Cardiovasc Comput Tomogr (Journal of cardiovascular computed tomography)
[2021, 15(3):285-287]

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Sex-Specific Computed Tomography Coronary Plaque Characterization and Risk of Myocardial Infarction.

Michelle C Williams, Jacek Kwiecinski, Mhairi Doris, Priscilla McElhinney, Michelle S D'Souza, Sebastien Cadet, Philip D Adamson, Alastair J Moss, Shirjel Alam, Amanda Hunter, Anoop S V Shah, Nicholas L Mills, Tania Pawade, Chengjia Wang, Jonathan R Weir-McCall, Michael Bonnici-Mallia, Christopher Murrills, Giles Roditi, Edwin J R van Beek, Leslee J Shaw, Edward D Nicol, Daniel S Berman, Piotr J Slomka, David E Newby, Marc R Dweck, Damini Dey,

<h4>Objectives</h4>This study was designed to investigate whether coronary computed tomography angiography assessments of coronary plaque might explain differences in the prognosis of men and women presenting with chest pain.<h4>Background</h4>Important sex differences exist in coronary artery disease. Women presenting with chest pain have different risk factors, symptoms, prevalence of coronary artery ... Read more >>

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2021, 14(9):1804-1814]

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Prevalence of Thrombotic Complications in ICU-Treated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning.

Saeed Mirsadraee, Diana A Gorog, Ciara F Mahon, Bhavin Rawal, Thomas R Semple, Edward D Nicol, Deepa R J Arachchillage, Anand Devaraj, Susanna Price, Sujal R Desai, Carole A Ridge, Suveer Singh, Simon P G Padley,

<h4>Objectives</h4>Severe coronavirus disease 2019 is associated with an extensive pneumonitis and frequent coagulopathy. We sought the true prevalence of thrombotic complications in critically ill patients with severe coronavirus disease 2019 on the ICU, with or without extracorporeal membrane oxygenation.<h4>Design</h4>We undertook a single-center, retrospective analysis of 72 critically ill patients with ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(5):804-815]

Cited: 4 times

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Prevalence and clinical implications of valvular calcification on coronary computed tomography angiography.

Michelle C Williams, Daniele Massera, Alastair J Moss, Rong Bing, Anda Bularga, Philip D Adamson, Amanda Hunter, Shirjel Alam, Anoop S V Shah, Tania Pawade, Giles Roditi, Edwin J R van Beek, Edward D Nicol, David E Newby, Marc R Dweck,

<h4>Aims</h4>Valvular heart disease can be identified by calcification on coronary computed tomography angiography (CCTA) and has been associated with adverse clinical outcomes. We assessed aortic and mitral valve calcification in patients presenting with stable chest pain and their association with cardiovascular risk factors, coronary artery disease, and cardiovascular outcomes.<h4>Methods and ... Read more >>

Eur Heart J Cardiovasc Imaging (European heart journal. Cardiovascular Imaging)
[2021, 22(3):262-270]

Cited: 1 time

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Multi-institution assessment of the use and risk of cardiovascular computed tomography in pediatric patients with congenital heart disease.

Mariana De Oliveira Nunes, Dawn R Witt, Susan A Casey, Cynthia K Rigsby, Anthony M Hlavacek, Shahryar M Chowdhury, Edward D Nicol, Thomas Semple, John R Lesser, Katelyn M Storey, Miranda S Kunz, Christian W Schmidt, Larissa I Stanberry, B Kelly Han,

<h4>Background</h4>Cardiac computed tomography (CT) is increasingly used in pediatric patients with congenital heart disease (CHD). Variability of practice and of comprehensive diagnostic risk across institutions is not known.<h4>Methods</h4>Four centers prospectively enrolled consecutive pediatric CHD patients <18 years of age undergoing cardiac CT from January 6, 2017 to 1/30/2020. Patient characteristics, ... Read more >>

J Cardiovasc Comput Tomogr (Journal of cardiovascular computed tomography)
[2021, 15(5):441-448]

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Radiation Exposure of Dual-Source Cardiovascular Computed Tomography in Patients With Congenital Heart Disease.

Mariana De Oliveira Nunes, Dawn R Witt, Susan A Casey, Cynthia K Rigsby, Anthony M Hlavacek, Shahryar M Chowdhury, Edward D Nicol, Thomas Semple, John R Lesser, B Kelly Han,

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2021, 14(3):698-700]

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SCCT 2021 Expert Consensus Document on Coronary Computed Tomographic Angiography: A Report of the Society of Cardiovascular Computed Tomography.

Jagat Narula, Y Chandrashekhar, Amir Ahmadi, Suhny Abbara, Daniel S Berman, Ron Blankstein, Jonathon Leipsic, David Newby, Edward D Nicol, Koen Nieman, Leslee Shaw, Todd C Villines, Michelle Williams, Harvey S Hecht,

J Cardiovasc Comput Tomogr (Journal of cardiovascular computed tomography)
[2021, 15(3):192-217]

Cited: 4 times

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Are conflict of interest declarations appropriate to allow sufficient consideration of potential bias in presentations?

William Crawford, C Fielder Camm, Ishika Prachee, Jack Olivarius-McAllister, Matthew R Ginks, Edward D Nicol,

<h4>Background</h4>Potential conflicts of interest (CoI) are common in medical research, necessitating the use of CoI declarations. There is currently no consensus document or external authority guiding CoI declarations in conference settings, resulting in declarations of variable quality and utility.<h4>Methods</h4>We explored four CoI declaration parameters (sufficient slide display time; the presence ... Read more >>

Future Healthc J (Future healthcare journal)
[2020, 7(3):226-229]

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Using FFRCT to Guide Management Strategy in Women: Two Steps Forward and One Step Back.

Edward D Nicol, Jonathan R Weir-McCall,

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2020, 13(12):2588-2590]

Cited: 0 times

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Opportunities and challenges of implementing computed tomography fractional flow reserve into clinical practice.

Muhummad Sohaib Nazir, Tarun K Mittal, Jonathan Weir-McCall, Koen Nieman, Keith Channon, Edward D Nicol,

CT-derived fractional flow reserve (CT-FFR) uses computational fluid dynamics to derive non-invasive FFR to determine the haemodynamic significance of coronary artery lesions. Studies have demonstrated good diagnostic accuracy of CT-FFR and reassuring short-term clinical outcome data.As a prerequisite, high-quality CT coronary angiography (CTCA) images are required with good heart rate ... Read more >>

Heart (Heart (British Cardiac Society))
[2020, 106(18):1387-1393]

Cited: 1 time

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Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease.

John A Spertus, Philip G Jones, David J Maron, Daniel B Mark, Sean M O'Brien, Jerome L Fleg, Harmony R Reynolds, Gregg W Stone, Mandeep S Sidhu, Bernard R Chaitman, Glenn M Chertow, Judith S Hochman, Sripal Bangalore, ,

<h4>Background</h4>In the ISCHEMIA-CKD trial, the primary analysis showed no significant difference in the risk of death or myocardial infarction with initial angiography and revascularization plus guideline-based medical therapy (invasive strategy) as compared with guideline-based medical therapy alone (conservative strategy) in participants with stable ischemic heart disease, moderate or severe ischemia, ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 382(17):1619-1628]

Cited: 5 times

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Health-Status Outcomes with Invasive or Conservative Care in Coronary Disease.

John A Spertus, Philip G Jones, David J Maron, Sean M O'Brien, Harmony R Reynolds, Yves Rosenberg, Gregg W Stone, Frank E Harrell, William E Boden, William S Weintraub, Khaula Baloch, Kreton Mavromatis, Ariel Diaz, Gilbert Gosselin, Jonathan D Newman, Stavroula Mavromichalis, Karen P Alexander, David J Cohen, Sripal Bangalore, Judith S Hochman, Daniel B Mark, ,

<h4>Background</h4>In the ISCHEMIA trial, an invasive strategy with angiographic assessment and revascularization did not reduce clinical events among patients with stable ischemic heart disease and moderate or severe ischemia. A secondary objective of the trial was to assess angina-related health status among these patients.<h4>Methods</h4>We assessed angina-related symptoms, function, and quality ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 382(15):1408-1419]

Cited: 36 times

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CT imaging prior to transcatheter aortic valve implantation in the UK.

Iwan Harries, Jonathan R Weir-McCall, Michelle C Williams, James Shambrook, Giles Roditi, Russel Bull, Gareth J Morgan-Hughes, Edward D Nicol, Alastair J Moss,

<h4>Objective</h4>This cross-sectional observational study sought to describe variations in CT in the context of transcatheter aortic valve implantation (CT-TAVI) as currently performed in the UK.<h4>Methods</h4>408 members of the British Society of Cardiovascular Imaging were invited to complete a 27-item online CT-TAVI survey.<h4>Results</h4>47 responses (12% response rate) were received from 40 ... Read more >>

Open Heart (Open heart)
[2020, 7(1):e001233]

Cited: 0 times

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Management of Coronary Disease in Patients with Advanced Kidney Disease.

Sripal Bangalore, David J Maron, Sean M O'Brien, Jerome L Fleg, Evgeny I Kretov, Carlo Briguori, Upendra Kaul, Harmony R Reynolds, Tomasz Mazurek, Mandeep S Sidhu, Jeffrey S Berger, Roy O Mathew, Olga Bockeria, Samuel Broderick, Radoslaw Pracon, Charles A Herzog, Zhen Huang, Gregg W Stone, William E Boden, Jonathan D Newman, Ziad A Ali, Daniel B Mark, John A Spertus, Karen P Alexander, Bernard R Chaitman, Glenn M Chertow, Judith S Hochman, ,

<h4>Background</h4>Clinical trials that have assessed the effect of revascularization in patients with stable coronary disease have routinely excluded those with advanced chronic kidney disease.<h4>Methods</h4>We randomly assigned 777 patients with advanced kidney disease and moderate or severe ischemia on stress testing to be treated with an initial invasive strategy consisting of ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 382(17):1608-1618]

Cited: 45 times

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Initial Invasive or Conservative Strategy for Stable Coronary Disease.

David J Maron, Judith S Hochman, Harmony R Reynolds, Sripal Bangalore, Sean M O'Brien, William E Boden, Bernard R Chaitman, Roxy Senior, Jose López-Sendón, Karen P Alexander, Renato D Lopes, Leslee J Shaw, Jeffrey S Berger, Jonathan D Newman, Mandeep S Sidhu, Shaun G Goodman, Witold Ruzyllo, Gilbert Gosselin, Aldo P Maggioni, Harvey D White, Balram Bhargava, James K Min, G B John Mancini, Daniel S Berman, Michael H Picard, Raymond Y Kwong, Ziad A Ali, Daniel B Mark, John A Spertus, Mangalath N Krishnan, Ahmed Elghamaz, Nagaraja Moorthy, Whady A Hueb, Marcin Demkow, Kreton Mavromatis, Olga Bockeria, Jesus Peteiro, Todd D Miller, Hanna Szwed, Rolf Doerr, Matyas Keltai, Joseph B Selvanayagam, P Gabriel Steg, Claes Held, Shun Kohsaka, Stavroula Mavromichalis, Ruth Kirby, Neal O Jeffries, Frank E Harrell, Frank W Rockhold, Samuel Broderick, T Bruce Ferguson, David O Williams, Robert A Harrington, Gregg W Stone, Yves Rosenberg, ,

<h4>Background</h4>Among patients with stable coronary disease and moderate or severe ischemia, whether clinical outcomes are better in those who receive an invasive intervention plus medical therapy than in those who receive medical therapy alone is uncertain.<h4>Methods</h4>We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 382(15):1395-1407]

Cited: 176 times

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Low-Attenuation Noncalcified Plaque on Coronary Computed Tomography Angiography Predicts Myocardial Infarction: Results From the Multicenter SCOT-HEART Trial (Scottish Computed Tomography of the HEART).

Michelle C Williams, Jacek Kwiecinski, Mhairi Doris, Priscilla McElhinney, Michelle S D'Souza, Sebastien Cadet, Philip D Adamson, Alastair J Moss, Shirjel Alam, Amanda Hunter, Anoop S V Shah, Nicholas L Mills, Tania Pawade, Chengjia Wang, Jonathan Weir McCall, Michael Bonnici-Mallia, Christopher Murrills, Giles Roditi, Edwin J R van Beek, Leslee J Shaw, Edward D Nicol, Daniel S Berman, Piotr J Slomka, David E Newby, Marc R Dweck, Damini Dey,

<h4>Background</h4>The future risk of myocardial infarction is commonly assessed using cardiovascular risk scores, coronary artery calcium score, or coronary artery stenosis severity. We assessed whether noncalcified low-attenuation plaque burden on coronary CT angiography (CCTA) might be a better predictor of the future risk of myocardial infarction.<h4>Methods</h4>In a post hoc analysis ... Read more >>

Circulation (Circulation)
[2020, 141(18):1452-1462]

Cited: 17 times

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Occupational Cardiology: The need for a 21st century sub-specialty?

Edward D Nicol, Joanna L D'Arcy, Maj Thomas Syburra, David A Holdsworth,

Eur Heart J (European heart journal)
[2019, 40(48):3878-3881]

Cited: 0 times

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Occupational coronary artery disease assessment: moving beyond the stenosis paradigm.

Edward D Nicol, Gary W Gray, Eddie D Davenport,

Eur Heart J (European heart journal)
[2019, 40(34):2844-2846]

Cited: 0 times

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Clinical occupational assessment pre- and post-cardiac surgery.

Maj Thomas Syburra, Norbert Guettler, Joanna L D'Arcy, Edward D Nicol,

Eur Heart J (European heart journal)
[2019, 40(40):3283-3286]

Cited: 0 times

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The importance of exercise testing in occupational cardiovascular assessment for high-hazard professions.

David A Holdsworth, Rebecca R Chamley, Oliver J Rider, Edward D Nicol,

Eur Heart J (European heart journal)
[2019, 40(37):3078-3080]

Cited: 0 times

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The assessment of asymptomatic inherited QT prolongation for high-hazard occupations.

Norbert Guettler, Kim Rajappan, David A Holdsworth, Edward D Nicol,

Eur Heart J (European heart journal)
[2019, 40(33):2750-2753]

Cited: 0 times

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ECG interpretation.

Rebecca R Chamley, David A Holdsworth, Kim Rajappan, Edward D Nicol,

Eur Heart J (European heart journal)
[2019, 40(32):2663-2666]

Cited: 1 time

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