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Author Edward C Jauch

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Systems of Care for ST-Segment-Elevation Myocardial Infarction: A Policy Statement From the American Heart Association.

Alice K Jacobs, Murtuza J Ali, Patricia J Best, Mark C Bieniarz, Vincent J Bufalino, William J French, Timothy D Henry, Lori Hollowell, Edward C Jauch, Michael C Kurz, Michael Levy, Puja Patel, Travis Spier, R Harper Stone, Katie L Tataris, Randal J Thomas, Jessica K Zègre-Hemsey, ,

The introduction of Mission: Lifeline significantly increased timely access to percutaneous coronary intervention for patients with ST-segment-elevation myocardial infarction (STEMI). In the years since, morbidity and mortality rates have declined, and research has led to significant developments that have broadened our concept of the STEMI system of care. However, significant ... Read more >>

Circulation (Circulation)
[2021, :CIR0000000000001025]

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Correction to: Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group.

Katharina A M Hackenberg, Ale Algra, Rustam Al-Shahi Salman, Juhana Frösen, David Hasan, Seppo Juvela, David Langer, Philip Meyers, Akio Morita, Gabriel Rinkel, Nima Etminan, ,

Neurocrit Care (Neurocritical care)
[2021, :]

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Recommendations for Regional Stroke Destination Plans in Rural, Suburban, and Urban Communities From the Prehospital Stroke System of Care Consensus Conference: A Consensus Statement From the American Academy of Neurology, American Heart Association/American Stroke Association, American Society of Neuroradiology, National Association of EMS Physicians, National Association of State EMS Officials, Society of NeuroInterventional Surgery, and Society of Vascular and Interventional Neurology: Endorsed by the Neurocritical Care Society.

Edward C Jauch, Lee H Schwamm, Peter D Panagos, Jolene Barbazzeni, Robert Dickson, Robert Dunne, Jenevra Foley, Justin F Fraser, Geoffrey Lassers, Christian Martin-Gill, Suzanne O'Brien, Mark Pinchalk, Shyam Prabhakaran, Christopher T Richards, Peter Taillac, Albert W Tsai, Anil Yallapragada, ,

Stroke (Stroke)
[2021, 52(5):e133-e152]

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Feasibility and Impact of the Combined Application of Coronary CT Angiography with the HEART Pathway in Patients with Suspected Acute Coronary Syndrome.

Andrew J Matuskowitz, Jihad S Obeid, Lindsey Jennings, Richard R Bayer, Viswanathan Ramakrishnan, U Joseph Schoepf, Edward C Jauch,

<h4>Background</h4>This study examines the feasibility and utility of integrating coronary CT angiography and the HEART Pathway into a novel accelerated diagnostic protocol - called HEART-CT - and assesses its impact as an optional interactive decision support tool (Smart Form) in the electronic health record.<h4>Methods</h4>This was a retrospective observational study performed ... Read more >>

Crit Pathw Cardiol (Critical pathways in cardiology)
[2021, :]

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The Utility of Domain-Specific End Points in Acute Stroke Trials.

Steven C Cramer, Steven L Wolf, Jeffrey L Saver, Karen C Johnston, J Mocco, Maarten G Lansberg, Sean I Savitz, David S Liebeskind, Wade Smith, Max Wintermark, Jordan J Elm, Pooja Khatri, Joseph P Broderick, Scott Janis, ,

Stroke (Stroke)
[2021, 52(3):1154-1161]

Cited: 0 times

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Does Emergency Medical Services Transportation Mitigate Post-stroke Discharge Disability? A Prospective Observational Study.

Sudha Xirasagar, Yuqi Wu, Khosrow Heidari, Jiera Zhou, Meng-Han Tsai, James W Hardin, Robert Wronski, Dana Hurley, Edward C Jauch, Souvik Sen,

<h4>Background</h4>Whether emergency medical services (EMS) transport improves disability outcomes compared with other transport among acute ischemic stroke (AIS) patients is unknown.<h4>Objective</h4>To study severity-adjusted associations of hospital arrival mode (EMS vs. other transport) with in-hospital and discharge disability outcomes.<h4>Design</h4>Prospective observational study.<h4>Participants</h4>AIS patients discharged April 2016 to October 2017 from a safety-net ... Read more >>

J Gen Intern Med (Journal of general internal medicine)
[2020, 35(11):3173-3180]

Cited: 0 times

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Determining the Need for Thrombectomy-Capable Stroke Centers Based on Travel Time to the Nearest Comprehensive Stroke Center.

David W Baker, Brette A Tschurtz, Amy E Aliaga, Scott C Williams, Edward C Jauch, Lee H Schwamm,

<h4>Background</h4>In January 2018 The Joint Commission introduced its Thrombectomy-Capable Stroke Center (TSC) certification program to recognize hospitals capable of performing endovascular thrombectomy for patients with ischemic strokes due to large vessel occlusions, intended for hospitals not in close geographic proximity to Comprehensive Stroke Centers (CSCs). This study was conducted to ... Read more >>

Jt Comm J Qual Patient Saf (Joint Commission journal on quality and patient safety)
[2020, 46(9):501-505]

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Original and Modified Graeb Score Correlation With Intraventricular Hemorrhage and Clinical Outcome Prediction in Hyperacute Intracranial Hemorrhage.

Daniel-Alexandre Bisson, Mathew L Flaherty, Anwar S Shatil, David Gladstone, Dar Dowlatshahi, Janice Carrozzella, Liying Zhang, Michael D Hill, Andrew Demchuck, Richard I Aviv, ,

Background and Purpose- The Graeb score is a visual rating scale of intraventricular hemorrhage (IVH) on noncontrast head CT. Little data exist in the hyperacute (<6 hour) period for reliability and predictive value of the modified Graeb Score (mGS) or the original Graeb Score (oGS) for clinical outcomes or their ... Read more >>

Stroke (Stroke)
[2020, 51(6):1696-1702]

Cited: 1 time

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Effect of Recombinant Activated Coagulation Factor VII on Hemorrhage Expansion Among Patients With Spot Sign-Positive Acute Intracerebral Hemorrhage: The SPOTLIGHT and STOP-IT Randomized Clinical Trials.

David J Gladstone, Richard I Aviv, Andrew M Demchuk, Michael D Hill, Kevin E Thorpe, Jane C Khoury, Heidi J Sucharew, Fahad Al-Ajlan, Ken Butcher, Dar Dowlatshahi, Gord Gubitz, Stephanie De Masi, Judith Hall, David Gregg, Muhammad Mamdani, Michel Shamy, Richard H Swartz, C Martin Del Campo, Brett Cucchiara, Peter Panagos, Joshua N Goldstein, Janice Carrozzella, Edward C Jauch, Joseph P Broderick, Matthew L Flaherty, ,

<h4>Importance</h4>Intracerebral hemorrhage (ICH) is a devastating stroke type that lacks effective treatments. An imaging biomarker of ICH expansion-the computed tomography (CT) angiography spot sign-may identify a subgroup that could benefit from hemostatic therapy.<h4>Objective</h4>To investigate whether recombinant activated coagulation factor VII (rFVIIa) reduces hemorrhage expansion among patients with spot sign-positive ICH.<h4>Design, ... Read more >>

JAMA Neurol (JAMA neurology)
[2019, 76(12):1493-1501]

Cited: 9 times

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Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.

William J Powers, Alejandro A Rabinstein, Teri Ackerson, Opeolu M Adeoye, Nicholas C Bambakidis, Kyra Becker, José Biller, Michael Brown, Bart M Demaerschalk, Brian Hoh, Edward C Jauch, Chelsea S Kidwell, Thabele M Leslie-Mazwi, Bruce Ovbiagele, Phillip A Scott, Kevin N Sheth, Andrew M Southerland, Deborah V Summers, David L Tirschwell,

Background and Purpose- The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations in a single document for clinicians caring for adult patients with acute arterial ischemic stroke. The intended audiences are prehospital care providers, physicians, allied health professionals, and hospital administrators. These guidelines supersede the ... Read more >>

Stroke (Stroke)
[2019, 50(12):e344-e418]

Cited: 447 times

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Why acute ischemic stroke patients in the United States use or do not use emergency medical services transport? Findings of an inpatient survey.

Sudha Xirasagar, Meng-Han Tsai, Khosrow Heidari, James W Hardin, Yuqi Wu, Robert Wronski, Dana Hurley, Edward C Jauch, Souvik Sen,

<h4>Background</h4>Patients with acute ischemic stroke (AIS) who use emergency medical services (EMS) receive quicker reperfusion treatment which, in turn, mitigates post-stroke disability. However, nationally only 59% use EMS. We examined why AIS patients use or do not use EMS.<h4>Methods</h4>During 2016-2018, a convenience sample of AIS patients admitted to a primary ... Read more >>

BMC Health Serv Res (BMC health services research)
[2019, 19(1):929]

Cited: 3 times

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Cerebral Edema Associated With Large Hemispheric Infarction.

David S Liebeskind, Eric Jüttler, Yuriy Shapovalov, Ashley Yegin, Jaren Landen, Edward C Jauch,

Stroke (Stroke)
[2019, 50(9):2619-2625]

Cited: 5 times

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Biospecimens and Molecular and Cellular Biomarkers in Aneurysmal Subarachnoid Hemorrhage Studies: Common Data Elements and Standard Reporting Recommendations.

Sherry H-Y Chou, R Loch Macdonald, Emanuela Keller, ,

<h4>Introduction</h4>Development of clinical biomarkers to guide therapy is an important unmet need in aneurysmal subarachnoid hemorrhage (SAH). A wide spectrum of plausible biomarkers has been reported for SAH, but none have been validated due to significant variabilities in study design, methodology, laboratory techniques, and outcome endpoints.<h4>Methods</h4>A systematic review of SAH ... Read more >>

Neurocrit Care (Neurocritical care)
[2019, 30(Suppl 1):46-59]

Cited: 9 times

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Common Data Elements for Unruptured Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage: Recommendations from the Working Group on Hospital Course and Acute Therapies-Proposal of a Multidisciplinary Research Group.

Airton Leonardo de Oliveira Manoel, Mathieu van der Jagt, Sepideh Amin-Hanjani, Nicholas C Bambakidis, Gretchen M Brophy, Ketan Bulsara, Jan Claassen, E Sander Connolly, S Alan Hoffer, Brian L Hoh, Robert G Holloway, Adam G Kelly, Stephan A Mayer, Peter Nakaji, Alejandro A Rabinstein, Peter Vajkoczy, Mervyn D I Vergouwen, Henry Woo, Gregory J Zipfel, Jose I Suarez, ,

<h4>Introduction</h4>The Common Data Elements (CDEs) initiative is a National Institute of Health/National Institute of Neurological Disorders and Stroke (NINDS) effort to standardize naming, definitions, data coding, and data collection for observational studies and clinical trials in major neurological disorders. A working group of experts was established to provide recommendations for ... Read more >>

Neurocrit Care (Neurocritical care)
[2019, 30(Suppl 1):36-45]

Cited: 5 times

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Common Data Elements for Subarachnoid Hemorrhage and Unruptured Intracranial Aneurysms: Recommendations from the Working Group on Subject Characteristics.

Philippe Bijlenga, Akio Morita, Nerissa U Ko, J Mocco, Sandrine Morel, Yuichi Murayama, Marieke J H Wermer, Robert D Brown, ,

<h4>Background</h4>The National Institute of Neurological Disorders and Stroke (NINDS) Common Data Elements (CDEs) have been generated to standardize and define terms used by the scientific community. The widespread use of these CDEs promotes harmonized data collection in clinical research. The aim of the NINDS Unruptured Intracranial Aneurysms (UIA) and Subarachnoid ... Read more >>

Neurocrit Care (Neurocritical care)
[2019, 30(Suppl 1):20-27]

Cited: 3 times

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Prioritization and Timing of Outcomes and Endpoints After Aneurysmal Subarachnoid Hemorrhage in Clinical Trials and Observational Studies: Proposal of a Multidisciplinary Research Group.

Martin N Stienen, Johanna M Visser-Meily, Tom A Schweizer, Daniel Hänggi, R Loch Macdonald, Mervyn D I Vergouwen, ,

<h4>Introduction</h4>In studies on aneurysmal subarachnoid hemorrhage (SAH), substantial variability exists in the use and timing of outcomes and endpoints, which complicates interpretation and comparison of results between studies. The aim of the National Institute of Health/National Institute of Neurological Disorders and Stroke/National Library of Medicine Unruptured Intracranial Aneurysm (UIA) and ... Read more >>

Neurocrit Care (Neurocritical care)
[2019, 30(Suppl 1):102-113]

Cited: 11 times

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Common Data Elements for Unruptured Intracranial Aneurysms and Subarachnoid Hemorrhage Clinical Research: A National Institute for Neurological Disorders and Stroke and National Library of Medicine Project.

Jose I Suarez, Muniza K Sheikh, R Loch Macdonald, Sepideh Amin-Hanjani, Robert D Brown, Airton Leonardo de Oliveira Manoel, Colin P Derdeyn, Nima Etminan, Emanuela Keller, Peter D Leroux, Stephan A Mayer, Akio Morita, Gabriel Rinkel, Daniel Rufennacht, Martin N Stienen, James Torner, Mervyn D I Vergouwen, George K C Wong, ,

<h4>Objectives</h4>The goal for this project was to develop a comprehensive set of common data elements (CDEs), data definitions, case report forms and guidelines for use in unruptured intracranial aneurysm (UIA) and subarachnoid hemorrhage (SAH) clinical research, as part of a new joint effort between the National Institute of Neurological Disorders ... Read more >>

Neurocrit Care (Neurocritical care)
[2019, 30(Suppl 1):4-19]

Cited: 11 times

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Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group.

Katharina A M Hackenberg, Ale Algra, Rustam Al-Shahi Salman, Juhana Frösen, David Hasan, Seppo Juvela, David Langer, Philip Meyers, Akio Morita, Gabriel Rinkel, Nima Etminan, ,

<h4>Introduction</h4>Variability in usage and definition of data characteristics in previous cohort studies on unruptured intracranial aneurysms (UIA) complicated pooling and proper interpretation of these data. The aim of the National Institute of Health/National Institute of Neurological Disorders and Stroke UIA and Subarachnoid Hemorrhage (SAH) Common Data Elements (CDE) Project was ... Read more >>

Neurocrit Care (Neurocritical care)
[2019, 30(Suppl 1):87-101]

Cited: 5 times

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Common Data Elements for Unruptured Intracranial Aneurysm and Subarachnoid Hemorrhage Clinical Research: Recommendations from the Working Group on Long-Term Therapies.

George K C Wong, Janis J Daly, Denise H Rhoney, Joseph Broderick, Christopher Ogilvy, Y B Roos, Adnan Siddiqui, James Torner, ,

<h4>Objectives</h4>The goal for the long-term therapies (LTT) working group (WG) of the Unruptured Intracranial Aneurysm (UIA) and Subarachnoid Hemorrhage (SAH) common data elements (CDEs) was to develop a comprehensive set of CDEs, data definitions, case report forms, and guidelines for use in UIA and SAH LTT clinical research, as part ... Read more >>

Neurocrit Care (Neurocritical care)
[2019, 30(Suppl 1):79-86]

Cited: 1 time

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Common Data Elements for Radiological Imaging of Patients with Subarachnoid Hemorrhage: Proposal of a Multidisciplinary Research Group.

Katharina A M Hackenberg, Nima Etminan, Max Wintermark, Philip M Meyers, Giuseppe Lanzino, Daniel Rüfenacht, Timo Krings, John Huston, Gabriel Rinkel, Colin Derdeyn, ,

<h4>Introduction</h4>Lack of homogeneous definitions for imaging data and consensus on their relevance in the setting of subarachnoid hemorrhage and unruptured intracranial aneurysms lead to a difficulty of data pooling and lack of robust data. The aim of the National Institute of Health/National Institute of Neurological Disorders and Stroke, Unruptured Intracranial ... Read more >>

Neurocrit Care (Neurocritical care)
[2019, 30(Suppl 1):60-78]

Cited: 5 times

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Common Data Element for Unruptured Intracranial Aneurysm and Subarachnoid Hemorrhage: Recommendations from Assessments and Clinical Examination Workgroup/Subcommittee.

Rahul Damani, Stephan Mayer, Raj Dhar, Renee H Martin, Paul Nyquist, DaiWai M Olson, Jorge H Mejia-Mantilla, Susanne Muehlschlegel, Edward C Jauch, J Mocco, Tatsushi Mutoh, Jose I Suarez, ,

<h4>Background</h4>Clinical studies of subarachnoid hemorrhage (SAH) and unruptured cerebral aneurysms lack uniformity in terms of variables used for assessments and clinical examination of patients which has led to difficulty in comparing studies and performing meta-analyses. The overall goal of the National Institute of Health/National Institute of Neurological Disorders and Stroke ... Read more >>

Neurocrit Care (Neurocritical care)
[2019, 30(Suppl 1):28-35]

Cited: 9 times

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Recommendations for the Establishment of Stroke Systems of Care: A 2019 Update.

Opeolu Adeoye, Karin V Nyström, Dileep R Yavagal, Jean Luciano, Raul G Nogueira, Richard D Zorowitz, Alexander A Khalessi, Cheryl Bushnell, William G Barsan, Peter Panagos, Mark J Alberts, A Colby Tiner, Lee H Schwamm, Edward C Jauch,

In 2005, the American Stroke Association published recommendations for the establishment of stroke systems of care and in 2013 expanded on them with a statement on interactions within stroke systems of care. The aim of this policy statement is to provide a comprehensive review of the scientific evidence evaluating stroke ... Read more >>

Stroke (Stroke)
[2019, 50(7):e187-e210]

Cited: 37 times

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Fast Protocol for Treating Acute Ischemic Stroke by Emergency Physicians: What Took So Long?

Edward C Jauch, Christine A Holmstedt,

Ann Emerg Med (Annals of emergency medicine)
[2019, 73(2):113-115]

Cited: 0 times

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Is There a Neurologist in the House? A Summary of the Current State of Neurovascular Rotations for Emergency Medicine Residents.

Charles R Wira, Tracy E Madsen, Bernard P Chang, Jason T Nomura, Evie Marcolini, Nina T Gentile, Kraftin E Schreyer, Lisa H Merck, Matthew Siket, Karen Greenberg, Christopher G Zammit, Edward C Jauch, M Fernanda Bellolio, ,

<h4>Objectives</h4>Neurovascular and neurocritical care emergencies constitute a leading cause of morbidity/mortality. There has been great evolution in this field, including but not limited to extended time-window therapeutic interventions for acute ischemic stroke. The intent of this article is to evaluate the goals and future direction of clinical rotations in neurovascular ... Read more >>

AEM Educ Train (AEM education and training)
[2018, 2(Suppl Suppl 1):S56-S67]

Cited: 1 time

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A review of acute ischemic stroke triage protocol evidence: a context for discussion.

Alexander G Chartrain, Hazem Shoirah, Edward C Jauch, J Mocco,

Endovascular thrombectomy (EVT) is now the standard of care for eligible patients with acute ischemic stroke (AIS) secondary to emergent large vessel occlusion (ELVO). However, there remains uncertainty in how hospital systems can most efficiently route patients with suspected ELVO for EVT treatment. Given the relative geographic distribution of centers ... Read more >>

J Neurointerv Surg (Journal of neurointerventional surgery)
[2018, 10(11):1047-1052]

Cited: 3 times

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