Full Text Journal Articles by
Author E M Thompson

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Prognostic Importance of Pathological Fractures in Osteosarcomas.

G A Sheridan, L Mellon, E M Thompson, G M O'Kane, G C O'Toole,

Aims To investigate whether pathological fractures impact on osteosarcoma patient prognosis in Ireland. Methods This was a retrospective study over 22 years in a National Orthopaedic Oncology Centre. There were 117 nonfracture cases and 15 fracture cases. Outcome measures included 5 and 10 year event-free (EFS) and overall survival (OS). ... Read more >>

Ir Med J (Irish medical journal)
[2020, 112(10):1021]

Cited: 0 times

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Cardiac Leiomyosarcoma in a Cat Presenting for Bilateral Renal Neoplasia.

M E Schreeg, B J Evans, J Allen, M C Lewis, E Luckring, M Evola, D K Richard, K Piner, E M Thompson, D B Adin, D A Tokarz,

A 10-year-old neutered female domestic longhair cat was presented to a tertiary care veterinary hospital for evaluation of a right renal mass that was identified incidentally on abdominal radiographs and classified further as a sarcoma based on fine needle aspiration cytology. Further diagnostic workup, including ultrasound and cytology, identified a ... Read more >>

J Comp Pathol (Journal of comparative pathology)
[2019, 168:19-24]

Cited: 0 times

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Growth plate extracellular matrix-derived scaffolds for large bone defect healing.

G M Cunniffe, P J Díaz-Payno, J S Ramey, O R Mahon, A Dunne, E M Thompson, F J O'Brien, D J Kelly,

Limitations associated with demineralised bone matrix and other grafting materials have motivated the development of alternative strategies to enhance the repair of large bone defects. The growth plate (GP) of developing limbs contain a plethora of growth factors and matrix cues which contribute to long bone growth, suggesting that biomaterials ... Read more >>

Eur Cell Mater (European cells & materials)
[2017, 33:130-142]

Cited: 7 times

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Use of lumbar laminoplasty vs. laminotomy for transection of the filum terminale does not affect early complication rates or postoperative course.

M J Strong, E M Thompson, N Roundy, N R Selden,

<h4>Introduction</h4>Various techniques are used for spinal cord untethering. The purpose of this study was to compare patient characteristics, postoperative course, and early complications after laminotomy vs. laminoplasty for transection of the filum terminale for tethered cord release.<h4>Methods</h4>Retrospective analysis of clinical and magnetic resonance imaging data was undertaken for all patients ... Read more >>

Childs Nerv Syst (Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery)
[2015, 31(4):597-601]

Cited: 4 times

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Local adaptation for body color in Drosophila americana.

P J Wittkopp, G Smith-Winberry, L L Arnold, E M Thompson, A M Cooley, D C Yuan, Q Song, B F McAllister,

Pigmentation is one of the most variable traits within and between Drosophila species. Much of this diversity appears to be adaptive, with environmental factors often invoked as selective forces. Here, we describe the geographic structure of pigmentation in Drosophila americana and evaluate the hypothesis that it is a locally adapted ... Read more >>

Heredity (Edinb) (Heredity)
[2011, 106(4):592-602]

Cited: 29 times

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Risk and protective factors in the development of post-traumatic stress disorder symptoms among a cohort of students in two tertiary institutions post Hurricane Ivan.

E M Thompson, W D Abel,

<h4>Objective</h4>This study seeks to identify factors associated with post-traumatic stress disorder (PTSD) following Hurricane Ivan among a cohort of tertiary-level students in Jamaica.<h4>Methods</h4>A 22-item, self-administered questionnaire was administered to a non-random sample. Using parametric and non-parametric analyses, the relationship between PTSD symptoms and several variables was examined.<h4>Results</h4>Feeling anxious, worried or ... Read more >>

West Indian Med J (The West Indian medical journal)
[2009, 58(2):179-180]

Cited: 0 times

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Identification of the novel HLA-C allele Cw*0751.

E M Thompson, Z M Kashi, R K Martin, J L Alcorn, L Tidey,

We report the novel HLA-Cw allele HLA-Cw*0751. The allele was identified during routine sequence-based typing in our laboratory. The novel allele is identical to Cw*07020101 except for a single nucleotide change in codon 90.2 in position 268. HLA-Cw*0751 allele possesses an adenine at position 268 in exon 2, while HLA-Cw*07020101 ... Read more >>

Tissue Antigens (Tissue antigens)
[2008, 71(2):178-179]

Cited: 2 times

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Growth, behavior, and clinical findings in 27 patients with Kabuki (Niikawa-Kuroki) syndrome.

S M White, E M Thompson, A Kidd, R Savarirayan, A Turner, D Amor, M B Delatycki, M Fahey, A Baxendale, S White, E Haan, K Gibson, J L Halliday, A Bankier,

This study was undertaken to document the phenotype of Kabuki (Niikawa-Kuroki) syndrome in patients from Australia and New Zealand, with particular emphasis on growth patterns, behavior, and relationship between head circumference and intellectual level. Data on 27 children and adults with Kabuki (Niikawa-Kuroki) syndrome from Australia and New Zealand were ... Read more >>

Am J Med Genet A (American journal of medical genetics. Part A)
[2004, 127A(2):118-127]

Cited: 33 times

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PEHO and PEHO-like syndromes: report of five Australian cases.

M J Field, P Grattan-Smith, S M Piper, E M Thompson, E A Haan, M Edwards, S James, I Wilkinson, L C Adès,

PEHO syndrome is a rare progressive infantile encephalopathy with onset within the first few months of life. Few patients fulfilling the diagnostic criteria for PEHO syndrome have been reported outside Finland. Affected infants have facial dysmorphism and suffer from severe hypotonia, profound mental retardation, convulsions (often with a hypsarrhythmic EEG ... Read more >>

Am J Med Genet A (American journal of medical genetics. Part A)
[2003, 122A(1):6-12]

Cited: 13 times

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Mutation analysis in the MECP2 gene and genetic counselling for Rett syndrome.

H Gill, J P Cheadle, J Maynard, N Fleming, S Whatley, T Cranston, E M Thompson, H Leonard, M Davis, J Christodoulou, O Skjeldal, F Hanefeld, A Kerr, A Tandy, D Ravine, A Clarke,

J Med Genet (Journal of medical genetics)
[2003, 40(5):380-384]

Cited: 12 times

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A sebaceous cyst with a difference: Dermatobia hominis.

L J Harbin, M Khan, E M Thompson, R D Goldin,

Dermatobia hominis causes furuncular myiasis and is endemic to South America. This report describes a case in a young woman who had recently visited Belize, highlighting the importance of clinical history (including travel history) and close liaison between pathologist and surgeon. ... Read more >>

J Clin Pathol (Journal of clinical pathology)
[2002, 55(10):798-799]

Cited: 10 times

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Association of mesangial IgM with IgM deposits in the macula densa: an indication of non-specific macromolecule transport rather than immune reactant?

E M Thompson, D J Evans,

BACKGROUND:We observed IgM deposits in the macula densa of the distal convoluted tubule in some renal biopsies with mesangial IgM deposits and did a systematic study to investigate the frequency of this phenomenon. We compared the findings with those in IgA disease. METHODS:A total of 30 renal biopsies with either ... Read more >>

Nephrol Dial Transplant (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2001, 16(9):1910-1913]

Cited: 1 time

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Autoantigen glycoprotein 70 expression is regulated by a single locus, which acts as a checkpoint for pathogenic anti-glycoprotein 70 autoantibody production and hence for the corresponding development of severe nephritis, in lupus-prone PXSB mice.

M E Haywood, T J Vyse, A McDermott, E M Thompson, A Ida, M J Walport, S Izui, B J Morley,

Retroviral envelope glycoprotein gp70 is present in the sera of immunologically normal and autoimmune-prone strains of mice. However, only lupus-prone mice spontaneously develop gp70-anti-gp70 immune complexes (gp70IC), and these have been implicated in the development of nephritis. We investigated the genetic factors that affect the production of both free serum ... Read more >>

J Immunol (Journal of immunology (Baltimore, Md. : 1950))
[2001, 167(3):1728-1733]

Cited: 21 times

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Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation.

F Zhao, C G Weismann, M Satoda, M E Pierpont, E Sweeney, E M Thompson, B D Gelb,

To elucidate further the role, in normal development and in disease pathogenesis, of TFAP2B, a transcription factor expressed in neuroectoderm, we studied eight patients with Char syndrome and their families. Four novel mutations were identified, three residing in the basic domain, which is responsible for DNA binding, and a fourth ... Read more >>

Am J Hum Genet (American journal of human genetics)
[2001, 69(4):695-703]

Cited: 49 times

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Inducible nitric oxide synthase neutralizes carbamoylating potential of 1,3-bis(2-chloroethyl)-1-nitrosourea in c6 glioma cells.

J H Yin, D I Yang, H Chou, E M Thompson, J Xu, C Y Hsu,

Expression of iNOS in glioma and other tumors has been extensively documented but the effects of NO derived from iNOS on tumor-killing mechanisms of chemotherapy drugs remain to be fully defined. We note that increased NO synthesis by cytokine exposure or iNOS overexpression neutralized the cytotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and ... Read more >>

J Pharmacol Exp Ther (The Journal of pharmacology and experimental therapeutics)
[2001, 297(1):308-315]

Cited: 16 times

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Asymptomatic maternal myasthenia as a cause of the Pena-Shokeir phenotype.

L A Brueton, S M Huson, P M Cox, I Shirley, E M Thompson, P R Barnes, J Price, J Newsom-Davis, A Vincent,

We report six sibs with arthrogryposis multiplex congenita and a Pena-Shokeir phenotype, born to a healthy woman who was discovered to have asymptomatic myasthenia gravis (MG). This is the first report of anti-acetylcholine receptor (AChR) antibodies causing fetal akinesia/hypokinesia sequence in the offspring of an asymptomatic mother. ... Read more >>

Am J Med Genet (American journal of medical genetics)
[2000, 92(1):1-6]

Cited: 27 times

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Identification of intervals on chromosomes 1, 3, and 13 linked to the development of lupus in BXSB mice.

M E Haywood, M B Hogarth, J H Slingsby, S J Rose, P J Allen, E M Thompson, M A Maibaum, P Chandler, K A Davies, E Simpson, M J Walport, B J Morley,

<h4>Objective</h4>To identify intervals containing systemic lupus erythematosus (SLE) susceptibility alleles in the BXSB strain of mice.<h4>Methods</h4>We analyzed 286 (B10 x [B10 x BXSB]F1) backcross mice for a range of phenotypic traits associated with the development of SLE in BXSB mice. The mice were genotyped using 93 microsatellite markers, and the ... Read more >>

Arthritis Rheum (Arthritis and rheumatism)
[2000, 43(2):349-355]

Cited: 48 times

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Type IV phosphodiesterase inhibitor is effective in prevention and treatment of experimental crescentic glomerulonephritis.

F W Tam, J Smith, S Agarwal, A M Karkar, D Morel, E M Thompson, C D Pusey,

<h4>Background</h4>Tumour necrosis factor alpha (TNF-alpha) has an important role in acute glomerular inflammation. Rolipram, a type IV phosphodiesterase inhibitor, has multiple anti-inflammatory effects including inhibition of TNF-alpha synthesis.<h4>Methods</h4>We investigated the effects of rolipram in prevention and delayed treatment of crescentic glomerulonephritis in Wistar Kyoto rats. Glomerulonephritis was induced by injection ... Read more >>

Nephron (Nephron)
[2000, 84(1):58-66]

Cited: 15 times

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The KBG syndrome.

S F Smithson, E M Thompson, A G McKinnon, I S Smith, R M Winter,

We report on two boys with a combination of short stature, a broad face, macrodontia and developmental delay. These features suggest that they have the KBG syndrome, a rare but distinctive phenotype. The pattern of inheritance remains uncertain and both autosomal dominant and X-linked recessive inheritance should be considered in ... Read more >>

Clin Dysmorphol (Clinical dysmorphology)
[2000, 9(2):87-91]

Cited: 10 times

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Cerebral cortical dysplasia and digital constriction rings in Adams-Oliver syndrome.

R Savarirayan, E M Thompson, K J Abbott, M H Moore,

Adams-Oliver syndrome (AOS) is characterised by aplasia cutis congenita of the scalp and variable degrees of terminal transverse limb defects. Short fingers and hypoplastic nails also occur in this predominantly autosomal dominant syndrome which displays marked variability of expression and lack of penetrance in some cases. We describe a boy ... Read more >>

Am J Med Genet (American journal of medical genetics)
[1999, 86(1):15-19]

Cited: 19 times

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Hematopoietic growth factor after autologous peripheral blood transplantation: comparison of G-CSF and GM-CSF.

J Jansen, E M Thompson, S Hanks, A R Greenspan, J M Thompson, M J Dugan, L P Akard,

Autologous peripheral blood stem cell (PBSC) transplantation results in rapid hematologic recovery when sufficient numbers of CD34+ cells/kg are infused. Recent studies suggest that filgrastim (G-CSF) administration following transplantation leads to more rapid neutrophil recovery and lower total transplant costs. This study compares the use of G-CSF (5 microg/kg/day) with ... Read more >>

Bone Marrow Transplant (Bone marrow transplantation)
[1999, 23(12):1251-1256]

Cited: 10 times

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Preferential nuclear location of a transgene does not depend on its transcriptional activity during early mouse development.

E M Thompson, J P Renard,

Changes in chromatin structure play an important role in regulation of the HSP70.1 gene during mouse preimplantation development. Using in situ PCR we have now examined whether the spatial organization of an HSP70.1 luciferase transgene within the nucleus is also a factor in regulating its expression. The transgene showed a ... Read more >>

Chromosoma (Chromosoma)
[1998, 107(5):321-329]

Cited: 0 times

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High mobility group 1 (HMG1) protein in mouse preimplantation embryos.

F Spada, A Brunet, Y Mercier, J P Renard, M E Bianchi, E M Thompson,

High mobility group 1 protein (HMG1) has traditionally been considered a structural component of chromatin, possibly similar in function to histone H1. In fact, at the onset of Xenopus and Drosophila development, HMG1 appears to substitute for histone H1: HMG1 is abundant when histone H1 is absent after the midblastula ... Read more >>

Mech Dev (Mechanisms of development)
[1998, 76(1-2):57-66]

Cited: 16 times

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Development of scarring and renal failure in a rat model of crescentic glomerulonephritis.

F W Tam, J Smith, D Morel, A M Karkar, E M Thompson, H T Cook, C D Pusey,

<h4>Background</h4>The aim of this study was to develop and characterize a rat model of crescentic glomerulonephritis which progresses to glomerulosclerosis and renal failure.<h4>Methods</h4>Glomerulonephritis was induced in Wistar Kyoto rats by a single injection of rabbit anti-glomerular basement membrane antiserum. Albuminuria and serum creatinine were monitored. Kidneys were examined, from 2.5 ... Read more >>

Nephrol Dial Transplant (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[1999, 14(7):1658-1666]

Cited: 43 times

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Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.

E LeGouy, E M Thompson, C Muchardt, J P Renard,

Epigenetic regulation of gene expression through modification of chromatin organization is an important mechanism in the development of eucaryotic organisms. We investigated the developmentally regulated expression of the mouse mBRG1 and mbrm genes, which are homologous to the yeast SWI2 gene. Both proteins are involved in chromatin remodeling as components ... Read more >>

Dev Dyn (Developmental dynamics : an official publication of the American Association of Anatomists)
[1998, 212(1):38-48]

Cited: 47 times

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