Full Text Journal Articles by
Author E Kavanagh

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Hybrid repair versus conventional open repair for thoracic aortic arch aneurysms.

Ala Elhelali, Niamh Hynes, Declan Devane, Sherif Sultan, Edel P Kavanagh, Liam Morris, Dave Veerasingam, Fionnuala Jordan,

<h4>Background</h4>Thoracic aortic arch aneurysms (TAAs) can be a life-threatening condition due to the potential risk of rupture. Treatment is recommended when the risk of rupture is greater than the risk of surgical complications. Depending on the cause, size and growth rate of the TAA, treatment may vary from close observation ... Read more >>

Cochrane Database Syst Rev (The Cochrane database of systematic reviews)
[2021, 6:CD012923]

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Systematic review on the incidence and management of endovenous heat-induced thrombosis following endovenous thermal ablation of the great saphenous vein.

Donagh A Healy, Mark Twyford, Tony Moloney, Eamon G Kavanagh,

<h4>Objective</h4>A systematic review and meta-analysis was performed to determine the incidence of endovenous heat-induced thrombosis (EHIT) and evaluate its management after endovenous thermal ablation of the great saphenous vein (GSV).<h4>Methods</h4>MEDLINE and Embase were searched for studies with at least 100 patients who underwent great saphenous vein endovenous thermal ablation and ... Read more >>

J Vasc Surg Venous Lymphat Disord (Journal of vascular surgery. Venous and lymphatic disorders)
[2021, :]

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On the association between circulating biomarkers and atherosclerotic calcification in a cohort of arterial disease participants.

Rachel M Cahalane, Hilary E Barrett, Aisling M Ross, John J E Mulvihill, Helen Purtill, Logeswaran Selvarajah, Julie O'Brien, Eamon G Kavanagh, Michael A Moloneye, Siobhan M Egan, Fiona C Leahy, Tomás P Griffin, M N Islam, Paul M O'Shea, Michael T Walsh, Eibhlís M O'Connor,

<h4>Background and aims</h4>Atherosclerotic calcification is a powerful predictor of cardiovascular disease. This study aims to determine whether circulating levels of a local/systemic calcification inhibitor or a marker of bone formation correlate with measures of coronary or extracoronary calcification.<h4>Methods and results</h4>Clinical computed tomography (CT) was performed on 64 arterial disease participants ... Read more >>

Nutr Metab Cardiovasc Dis (Nutrition, metabolism, and cardiovascular diseases : NMCD)
[2021, 31(5):1533-1541]

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Multicenter Evaluation of 434 Hospital Deaths From COVID-19: How Can We Improve End-of-Life Care During a Pandemic?

Felicity Dewhurst, Hannah Billett, Lauri Simkiss, Charlotte Bryan, Julie Barnsley, Max Charles, Elizabeth Fleming, Jennifer Grieve, Sade Hacking, Kate Howorth, Amy Huggin, Emily Kavanagh, Rachel Kiltie, Lucy Lowery, Dene Miller, Alex Nicholson, Lucy Nicholson, Ann Paxton, Anna Porteous, Grace Rowley, Kaly Snell, Elizabeth Woods, Elizabeth Zabrocki, Katherine Frew, Leena Srivastava,

<h4>Context</h4>The pandemic has substantially increased the workload of hospital palliative care providers, requiring them to be responsive and innovative despite limited information on the specific end of life care needs of patients with COVID-19. Multi-site data detailing clinical characteristics of patient deaths from large populations, managed by specialist and generalist ... Read more >>

J Pain Symptom Manage (Journal of pain and symptom management)
[2021, 61(5):e7-e12]

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Open repair of a type II endoleak facilitated by temporary disconnection of graft components.

Aisling Kelly, Conor Toale, David Power, Eamon G Kavanagh, Michael A Moloney,

Endoleaks are a frequent indication for reintervention after endovascular repair of an abdominal aortic aneurysm. Here we present a method of open repair of a persistent type II endoleak involving graft component separation and reconstruction, in a patient with symptomatic interval aneurysmal sac enlargement despite endovascular coiling and embolization. This ... Read more >>

J Vasc Surg Cases Innov Tech (Journal of vascular surgery cases and innovative techniques)
[2021, 7(1):26-29]

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N-Linked glycosylation profiles of therapeutic induced senescent (TIS) triple negative breast cancer cells (TNBC) and their extracellular vesicle (EV) progeny.

Emma L Kavanagh, Melinda Halasz, Paul Dowling, Jo Withers, Sinéad Lindsay, Michaela J Higgins, Jane A Irwin, Pauline M Rudd, Radka Saldova, Amanda McCann,

Triple negative breast cancer (TNBC) has poor clinical outcomes and limited treatment options. Chemotherapy, while killing some cancer cells, can result in therapeutic-induced-senescent (TIS) cells. Senescent cells release significantly more extracellular vesicles (EVs) than non-senescent cells. Recently, N- and O-linked glycosylation alterations have been associated with senescence. We aimed to ... Read more >>

Mol Omics (Molecular omics)
[2021, 17(1):72-85]

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Tenosynovial chondromatosis of the flexor pollicis longus tendon: A subtype of primary synovial chondromatosis.

Alexandra Murphy, Bryan Yelverton, Danilo Vukanic, Zornitsa Tsvetanova, Sarah-Kate Eustace, Alan Molloy, Conor J O'Keane, Eoin Kavanagh,

Primary synovial chondromatosis is a rare benign neoplastic process, in which cartilaginous nodules are produced in the subsynovial tissue. It has 3 main subtypes (intra-articular, tenosynovial and bursal). We present the case of a 61-year-old female, with a mass involving her right thumb for at least 5 years, which had ... Read more >>

Radiol Case Rep (Radiology case reports)
[2021, 16(3):487-492]

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Correction to: The CLEAR (Considering Leading Experts' Antithrombotic Regimes around peripheral angioplasty) survey: an international perspective on antiplatelet and anticoagulant practice for peripheral arterial endovascular intervention.

Kitty H F Wong, Dave C Bosanquet, Graeme K Ambler, Mahim I Qureshi, Robert J Hinchliffe, Christopher P Twine, ,

An amendment to this paper has been published and can be accessed via the original article. ... Read more >>

CVIR Endovasc (CVIR endovascular)
[2020, 3(1):87]

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A Web Application About Herd Immunity Using Personalized Avatars: Development Study.

Hina Hakim, Julie A Bettinger, Christine T Chambers, S Michelle Driedger, Eve Dubé, Teresa Gavaruzzi, Anik M C Giguere, Éric Kavanagh, Julie Leask, Shannon E MacDonald, Rita Orji, Elizabeth Parent, Jean-Sébastien Paquette, Jacynthe Roberge, Beate Sander, Aaron M Scherer, Martin Tremblay-Breault, Kumanan Wilson, Daniel Reinharz, Holly O Witteman,

<h4>Background</h4>Herd immunity or community immunity refers to the reduced risk of infection among susceptible individuals in a population through the presence and proximity of immune individuals. Recent studies suggest that improving the understanding of community immunity may increase intentions to get vaccinated.<h4>Objective</h4>This study aims to design a web application about ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2020, 22(10):e20113]

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Adapting two American Decision Aids for Mild Traumatic Brain Injury to the Canadian Context Using the Nominal Group Technique.

El Kebir Ghandour, Lania Lelaidier Hould, Félix-Antoine Fortier, Veronique Gélinas, Edward R Melnick, Erik P Hess, Eddy S Lang, Jocelyn Gravel, Jeffrey J Perry, Natalie Le Sage, Catherine Truchon, Annie LeBlanc, Alexander Sasha Dubrovsky, Marie-Pierre Gagnon, Marie-Christine Ouellet, Isabelle Gagnon, Suzanne McKenna, France Légaré, Louise Sauvé, Tom H van de Belt, Éric Kavanagh, Laurence Paquette, Anne-Catherine Verrette, Patrick Plante, Richard J Riopelle, Patrick M Archambault, ,

<h4>Background</h4>Decision aids are patient-focused tools that have the potential to reduce the overuse of head computed tomography (CT) scans.<h4>Objective</h4>The objective of this study was to create a consensus among Canadian mild traumatic brain injury and emergency medicine experts on modifications required to adapt two American decision aids about head CT ... Read more >>

Patient (The patient)
[2020, 13(6):729-743]

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The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells.

Dalal AlSultan, Emma Kavanagh, Shane O'Grady, Alex J Eustace, Alina Castell, Lars-Gunnar Larsson, John Crown, Stephen F Madden, Michael J Duffy,

Background The MYC oncogene is one of the most frequently altered driver genes in cancer. MYC is thus a potential target for cancer treatment as well as a biomarker for the disease. However, as a target for treatment, MYC has traditionally been regarded as "undruggable" or difficult to target. We ... Read more >>

Invest New Drugs (Investigational new drugs)
[2021, 39(2):587-594]

Cited: 1 time

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Multimodal imaging of composite carbon fiber-based implants for orthopedic spinal fixation.

Francis T Delaney, Hazel Denton, Michael Dodds, Eoin C Kavanagh,

<h4>Objective</h4>As cancer treatments continue to improve, the incidence of spinal metastases and the need for surgical management of these with fixation procedures are growing rapidly. Traditionally metallic implants, composed of titanium alloy, have been used in surgical fixation of unstable or symptomatic vertebral metastases or traumatic injuries. Metallic implants, however, ... Read more >>

Skeletal Radiol (Skeletal radiology)
[2021, 50(5):1039-1045]

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Inequalities in awareness and availability of bereavement services in North-East England.

Donna Wakefield, Elizabeth Fleming, Kate Howorth, Kerry Waterfield, Emily Kavanagh, Hannah C Billett, Rachel Kiltie, Lucy Robinson, Grace Rowley, Jolene Brown, Elizabeth Woods, Felicity Dewhurst,

<h4>Objectives</h4>National guidance recommends equality in access to bereavement services; despite this, awareness and availability appears inconsistent. The aim of this study was to explore availability and accessibility of bereavement services across the North-East of England and to highlight issues potentially applicable across the UK, at a time of unprecedented need ... Read more >>

BMJ Support Palliat Care (BMJ supportive & palliative care)
[2020, :]

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Hybrid covered endovascular reconstruction of the aortic bifurcation (CERAB) procedure is preferable to aortobifemoral bypass for limb-threatening aortoiliac occlusive disease during the COVID-19 crisis.

Helen McElligott, Conor Toale, Eamon G Kavanagh, Michael A Moloney,

The COVID-19 pandemic is disrupting the provision of acute vascular surgery across the globe. Limited evidence of the impact of nosocomial infection on patient outcomes as well as concerns about critical care capacity will likely have an impact on surgical decision-making. Endovascular therapy offers a way by which perioperative risk ... Read more >>

J Vasc Surg Cases Innov Tech (Journal of vascular surgery cases and innovative techniques)
[2020, 6(4):703-706]

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Periprosthetic Hip Joint Infection and Its Diagnosis.

John P Hynes, Mark C Murphy, Ciara Gillespie, Eoin C Kavanagh,

Radiology (Radiology)
[2020, 297(1):E240]

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Correlating Ex Vivo Carotid Calcification Measurements With Cerebrovascular Symptoms: A Proof-of-Concept Study.

Rachel M Cahalane, Julie M O'Brien, Eamon G Kavanagh, Michael A Moloney, Fiona C Leahy, Michael T Walsh,

<h4>Background and purpose</h4>The purpose of this study is to examine the ability of ex vivo derived Agatston, Volume, and Density-Volume calcium scores or calcium density measurements to differentiate between carotid plaques based on preoperative cerebrovascular symptomatology.<h4>Methods</h4>Thirty-eight carotid plaques were acquired from standard endarterectomy. Micro-computed tomography was performed on the ex ... Read more >>

Stroke (Stroke)
[2020, 51(9):e250-e253]

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Auto-Decompression - Preserved Neurological Function in Bilateral Cervical Facet Dislocations.

T Ó Doinn, A J Hughes, D P Ahern, J McDonnell, E Kavanagh, S Morris, J S Butler,

Introduction Bilateral cervical facet dislocation (BCFD) is an uncommon injury with a high incidence of severe neurological impairment. We describe 4 cases of BCFD with preserved neurological function. Case 1: A 78-year-old female who suffered two ground level falls (GLFs). Pre-operative American Spinal Injury Association (ASIA) Score was C5D. Imaging ... Read more >>

Ir Med J (Irish medical journal)
[2020, 113(7):131]

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Complications in image-guided musculoskeletal injections.

John P Hynes, Meadhbh Ni Fhlatharta, James W Ryan, Peter J MacMahon, Stephen J Eustace, Eoin C Kavanagh,

<h4>Objective</h4>To establish the incidence and define the nature of complications occurring following image-guided musculoskeletal injections at our institution.<h4>Materials and methods</h4>All patients undergoing image-guided musculoskeletal injection during the study period (16/3/2016 to 24/01/2020) were included. Departmental records were reviewed to identify all patients describing possible complications following injection, what therapy was ... Read more >>

Skeletal Radiol (Skeletal radiology)
[2021, 50(2):343-349]

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Working Upstream in Advance Care Planning in Pandemic Palliative Care.

Milana Zaurova, Mona Krouss, Sigal Israilov, Louis Hart, Hillary Jalon, Georgia Conley, Khoi Luong, Eric K Wei, Robert Smeltz, Michael Frankenthaler, Jeffrey Nichols, Susan Cohen, Natasha Suleman, Marina Ivanyuk, Pavel Shulman, Osbely Tala, Lauren Parker, Tita Castor, Nicole Pearlstein, Elizabeth Kavanagh, Hyung J Cho,

Health Secur (Health security)
[2020, :]

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An international experience of electronic communication and implementation of eHealth solutions in a vascular surgery clinic.

Aisling Kelly, Jessica Belchos, Mark Wheatcroft, Paul E Burke, Yasser Abdeldaim, Eamon G Kavanagh, Norm Archer, Ann McKibbon, Michael A Moloney,

<h4>Introduction</h4>Communication is key to any successful relationship with the patient-physician partnership being no different. Recent advances in technology have provided us with an array of new communication tools such as the mobile phone, computer, internet, and email. This new technology has revolutionized communications; however, limitations to their widespread use include ... Read more >>

Ir J Med Sci (Irish journal of medical science)
[2021, 190(1):291-296]

Cited: 1 time

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Microglia: Agents of the CNS Pro-Inflammatory Response.

José A Rodríguez-Gómez, Edel Kavanagh, Pinelopi Engskog-Vlachos, Mikael K R Engskog, Antonio J Herrera, Ana M Espinosa-Oliva, Bertrand Joseph, Nabil Hajji, José L Venero, Miguel A Burguillos,

The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative diseases. Though the research of microglia spans over a century, the last two decades have increased our understanding exponentially. Here, we discuss the phenotypic transformation from homeostatic microglia towards reactive microglia, initiated by ... Read more >>

Cells (Cells)
[2020, 9(7):]

Cited: 11 times

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Cohort profile: BIOVASC-late, a prospective multicentred study of imaging and blood biomarkers of carotid plaque inflammation and risk of late vascular recurrence after non-severe stroke in Ireland.

John Joseph McCabe, Nicola Giannotti, Jonathan McNulty, Sean Collins, Sarah Coveney, Sean Murphy, Mary Barry, Joseph Harbison, Simon Cronin, David Williams, Gillian Horgan, Eamon Dolan, Tim Cassidy, Ciaran McDonnell, Eoin Kavanagh, Shane Foley, Martin O'Connell, Michael Marnane, Peter Kelly,

<h4>Purpose</h4>Inflammation is important in stroke. Anti-inflammatory therapy reduces vascular events in coronary patients. <sup>18</sup>F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) identifies plaque inflammation-related metabolism. However, long-term prospective cohort studies investigating the association between carotid plaque inflammation, identified on <sup>18</sup>F-FDG PET and the risk of recurrent vascular events, have not yet been undertaken ... Read more >>

BMJ Open (BMJ open)
[2020, 10(7):e038607]

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Placebo effects in musculoskeletal radiology procedures.

Charles J Sullivan, Stephen J Eustace, Eoin C Kavanagh,

Skeletal Radiol (Skeletal radiology)
[2020, 49(12):1921-1924]

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Reducing the risk of venous thromboembolism following superficial endovenous treatment: A UK and Republic of Ireland consensus study.

Nikesh Dattani, Joseph Shalhoub, Sandip Nandhra, Tristan Lane, Abdulsalam Abu-Own, Ahmed Elbasty, Aled Jones, Andrew Duncan, Andrew Garnham, Ankur Thapar, Anna Murray, Anzar Baig, Athanasios Saratzis, Atif Sharif, Bella Huasen, Claire Dawkins, Craig Nesbitt, Daniel Carradice, Darren Morrow, David Bosanquet, Eamon Kavanagh, Faisal Shaikh, Gergely Gosi, Graeme Ambler, Gregory Fulton, Gurdas Singh, Hannah Travers, Hayley Moore, James Olivier, Louise Hitchman, Martin O'Donohoe, Matthew Popplewell, Mekki Medani, Michael Jenkins, Mingzheng A Goh, Oliver Lyons, Olivia McBride, Paul Moxey, Philip Stather, Phillipa Burns, Rachel Forsythe, Rachel Sam, Ranjeet Brar, Robert Brightwell, Ruth Benson, Sarah Onida, Sharath Paravastu, Simon Lambracos, Srinivasa R Vallabhaneni, Stewart Walsh, Tasleem Aktar, Tony Moloney, Zola Mzimba, Isaac Nyamekye,

<h4>Objectives</h4>Venous thromboembolism is a potentially fatal complication of superficial endovenous treatment. Proper risk assessment and thromboprophylaxis could mitigate this hazard; however, there are currently no evidence-based or consensus guidelines. This study surveyed UK and Republic of Ireland vascular consultants to determine areas of consensus.<h4>Methods</h4>A 32-item survey was sent to vascular ... Read more >>

Phlebology (Phlebology)
[2020, 35(9):706-714]

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Pigmented villonodular synovitis of the hip joint: Three cases demonstrating characteristic MRI features.

Charles J Sullivan, Stephen J Eustace, Eoin C Kavanagh,

Pigmented villonodular synovitis is a rare benign proliferative disease of synovial membranes, causing villonodular synovial hyperplasia and hemosiderin deposition. Its intra-articular forms most commonly affect the knee and less commonly the hip. PVNS of the hip is most common in the second to fifth decades and presentation is typically with ... Read more >>

Radiol Case Rep (Radiology case reports)
[2020, 15(8):1335-1338]

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