Full Text Journal Articles by
Author E Kavanagh

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A Web Application About Herd Immunity Using Personalized Avatars: Development Study.

Hina Hakim, Julie A Bettinger, Christine T Chambers, S Michelle Driedger, Eve Dubé, Teresa Gavaruzzi, Anik M C Giguere, Éric Kavanagh, Julie Leask, Shannon E MacDonald, Rita Orji, Elizabeth Parent, Jean-Sébastien Paquette, Jacynthe Roberge, Beate Sander, Aaron M Scherer, Martin Tremblay-Breault, Kumanan Wilson, Daniel Reinharz, Holly O Witteman,

BACKGROUND:Herd immunity or community immunity refers to the reduced risk of infection among susceptible individuals in a population through the presence and proximity of immune individuals. Recent studies suggest that improving the understanding of community immunity may increase intentions to get vaccinated. OBJECTIVE:This study aims to design a web application ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2020, 22(10):e20113]

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Adapting two American Decision Aids for Mild Traumatic Brain Injury to the Canadian Context Using the Nominal Group Technique.

El Kebir Ghandour, Lania Lelaidier Hould, Félix-Antoine Fortier, Veronique Gélinas, Edward R Melnick, Erik P Hess, Eddy S Lang, Jocelyn Gravel, Jeffrey J Perry, Natalie Le Sage, Catherine Truchon, Annie LeBlanc, Alexander Sasha Dubrovsky, Marie-Pierre Gagnon, Marie-Christine Ouellet, Isabelle Gagnon, Suzanne McKenna, France Légaré, Louise Sauvé, Tom H van de Belt, Éric Kavanagh, Laurence Paquette, Anne-Catherine Verrette, Patrick Plante, Richard J Riopelle, Patrick M Archambault, ,

BACKGROUND:Decision aids are patient-focused tools that have the potential to reduce the overuse of head computed tomography (CT) scans. OBJECTIVE:The objective of this study was to create a consensus among Canadian mild traumatic brain injury and emergency medicine experts on modifications required to adapt two American decision aids about head ... Read more >>

Patient (The patient)
[2020, 13(6):729-743]

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The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells.

Dalal AlSultan, Emma Kavanagh, Shane O'Grady, Alex J Eustace, Alina Castell, Lars-Gunnar Larsson, John Crown, Stephen F Madden, Michael J Duffy,

Background The MYC oncogene is one of the most frequently altered driver genes in cancer. MYC is thus a potential target for cancer treatment as well as a biomarker for the disease. However, as a target for treatment, MYC has traditionally been regarded as "undruggable" or difficult to target. We ... Read more >>

Invest New Drugs (Investigational new drugs)
[2020, :]

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Multimodal imaging of composite carbon fiber-based implants for orthopedic spinal fixation.

Francis T Delaney, Hazel Denton, Michael Dodds, Eoin C Kavanagh,

OBJECTIVE:As cancer treatments continue to improve, the incidence of spinal metastases and the need for surgical management of these with fixation procedures are growing rapidly. Traditionally metallic implants, composed of titanium alloy, have been used in surgical fixation of unstable or symptomatic vertebral metastases or traumatic injuries. Metallic implants, however, ... Read more >>

Skeletal Radiol (Skeletal radiology)
[2020, :]

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Inequalities in awareness and availability of bereavement services in North-East England.

Donna Wakefield, Elizabeth Fleming, Kate Howorth, Kerry Waterfield, Emily Kavanagh, Hannah C Billett, Rachel Kiltie, Lucy Robinson, Grace Rowley, Jolene Brown, Elizabeth Woods, Felicity Dewhurst,

OBJECTIVES:National guidance recommends equality in access to bereavement services; despite this, awareness and availability appears inconsistent. The aim of this study was to explore availability and accessibility of bereavement services across the North-East of England and to highlight issues potentially applicable across the UK, at a time of unprecedented need ... Read more >>

BMJ Support Palliat Care (BMJ supportive & palliative care)
[2020, :]

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Hybrid-CERAB (Covered Endovascular Reconstruction of the Aortic Bifurcation) Procedure is preferable to Aorto-Bi-Femoral Bypass for Limb-threatening Aortoiliac Occlusive Disease during the COVID-19 Crisis.

Helen McElligott, Conor Toale, Michael A Moloney, Eamon G Kavanagh,

The COVID-19 pandemic is disrupting the provision of acute vascular surgery across the globe. Limited evidence regarding the impact of nosocomial infection on patient outcomes, as well as concerns regarding critical care capacity, will likely impact upon surgical decision making. Endovascular therapy offers a way by which peri-operative risk can ... Read more >>

(Journal of vascular surgery cases and innovative techniques)
[2020, :]

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Periprosthetic Hip Joint Infection and Its Diagnosis.

John P Hynes, Mark C Murphy, Ciara Gillespie, Eoin C Kavanagh,

Radiology (Radiology)
[2020, 297(1):E240]

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Correlating Ex Vivo Carotid Calcification Measurements With Cerebrovascular Symptoms: A Proof-of-Concept Study.

Rachel M Cahalane, Julie M O'Brien, Eamon G Kavanagh, Michael A Moloney, Fiona C Leahy, Michael T Walsh,

BACKGROUND AND PURPOSE:The purpose of this study is to examine the ability of ex vivo derived Agatston, Volume, and Density-Volume calcium scores or calcium density measurements to differentiate between carotid plaques based on preoperative cerebrovascular symptomatology. METHODS:Thirty-eight carotid plaques were acquired from standard endarterectomy. Micro-computed tomography was performed on the ... Read more >>

Stroke (Stroke)
[2020, 51(9):e250-e253]

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Auto-Decompression - Preserved Neurological Function in Bilateral Cervical Facet Dislocations.

T Ó Doinn, A J Hughes, D P Ahern, J McDonnell, E Kavanagh, S Morris, J S Butler,

Introduction Bilateral cervical facet dislocation (BCFD) is an uncommon injury with a high incidence of severe neurological impairment. We describe 4 cases of BCFD with preserved neurological function. Case 1: A 78-year-old female who suffered two ground level falls (GLFs). Pre-operative American Spinal Injury Association (ASIA) Score was C5D. Imaging ... Read more >>

Ir Med J (Irish medical journal)
[2020, 113(7):131]

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Complications in image-guided musculoskeletal injections.

John P Hynes, Meadhbh Ni Fhlatharta, James W Ryan, Peter J MacMahon, Stephen J Eustace, Eoin C Kavanagh,

OBJECTIVE:To establish the incidence and define the nature of complications occurring following image-guided musculoskeletal injections at our institution. MATERIALS AND METHODS:All patients undergoing image-guided musculoskeletal injection during the study period (16/3/2016 to 24/01/2020) were included. Departmental records were reviewed to identify all patients describing possible complications following injection, what therapy ... Read more >>

Skeletal Radiol. (Skeletal radiology)
[2020, :]

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Working Upstream in Advance Care Planning in Pandemic Palliative Care.

Milana Zaurova, Mona Krouss, Sigal Israilov, Louis Hart, Hillary Jalon, Georgia Conley, Khoi Luong, Eric K Wei, Robert Smeltz, Michael Frankenthaler, Jeffrey Nichols, Susan Cohen, Natasha Suleman, Marina Ivanyuk, Pavel Shulman, Osbely Tala, Lauren Parker, Tita Castor, Nicole Pearlstein, Elizabeth Kavanagh, Hyung J Cho,

Health Secur (Health security)
[2020, :]

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An international experience of electronic communication and implementation of eHealth solutions in a vascular surgery clinic.

Aisling Kelly, Jessica Belchos, Mark Wheatcroft, Paul E Burke, Yasser Abdeldaim, Eamon G Kavanagh, Norm Archer, Ann McKibbon, Michael A Moloney,

INTRODUCTION:Communication is key to any successful relationship with the patient-physician partnership being no different. Recent advances in technology have provided us with an array of new communication tools such as the mobile phone, computer, internet, and email. This new technology has revolutionized communications; however, limitations to their widespread use include ... Read more >>

Ir J Med Sci (Irish journal of medical science)
[2020, :]

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Microglia: Agents of the CNS Pro-Inflammatory Response.

José A Rodríguez-Gómez, Edel Kavanagh, Pinelopi Engskog-Vlachos, Mikael K R Engskog, Antonio J Herrera, Ana M Espinosa-Oliva, Bertrand Joseph, Nabil Hajji, José L Venero, Miguel A Burguillos,

The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative diseases. Though the research of microglia spans over a century, the last two decades have increased our understanding exponentially. Here, we discuss the phenotypic transformation from homeostatic microglia towards reactive microglia, initiated by ... Read more >>

Cells (Cells)
[2020, 9(7):]

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Cohort profile: BIOVASC-late, a prospective multicentred study of imaging and blood biomarkers of carotid plaque inflammation and risk of late vascular recurrence after non-severe stroke in Ireland.

John Joseph McCabe, Nicola Giannotti, Jonathan McNulty, Sean Collins, Sarah Coveney, Sean Murphy, Mary Barry, Joseph Harbison, Simon Cronin, David Williams, Gillian Horgan, Eamon Dolan, Tim Cassidy, Ciaran McDonnell, Eoin Kavanagh, Shane Foley, Martin O'Connell, Michael Marnane, Peter Kelly,

PURPOSE:Inflammation is important in stroke. Anti-inflammatory therapy reduces vascular events in coronary patients. 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) identifies plaque inflammation-related metabolism. However, long-term prospective cohort studies investigating the association between carotid plaque inflammation, identified on 18F-FDG PET and the risk of recurrent vascular events, have not yet been undertaken ... Read more >>

BMJ Open (BMJ open)
[2020, 10(7):e038607]

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Placebo effects in musculoskeletal radiology procedures.

Charles J Sullivan, Stephen J Eustace, Eoin C Kavanagh,

Skeletal Radiol (Skeletal radiology)
[2020, 49(12):1921-1924]

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Reducing the risk of venous thromboembolism following superficial endovenous treatment: A UK and Republic of Ireland consensus study.

Nikesh Dattani, Joseph Shalhoub, Sandip Nandhra, Tristan Lane, Abdulsalam Abu-Own, Ahmed Elbasty, Aled Jones, Andrew Duncan, Andrew Garnham, Ankur Thapar, Anna Murray, Anzar Baig, Athanasios Saratzis, Atif Sharif, Bella Huasen, Claire Dawkins, Craig Nesbitt, Daniel Carradice, Darren Morrow, David Bosanquet, Eamon Kavanagh, Faisal Shaikh, Gergely Gosi, Graeme Ambler, Gregory Fulton, Gurdas Singh, Hannah Travers, Hayley Moore, James Olivier, Louise Hitchman, Martin O'Donohoe, Matthew Popplewell, Mekki Medani, Michael Jenkins, Mingzheng A Goh, Oliver Lyons, Olivia McBride, Paul Moxey, Philip Stather, Phillipa Burns, Rachel Forsythe, Rachel Sam, Ranjeet Brar, Robert Brightwell, Ruth Benson, Sarah Onida, Sharath Paravastu, Simon Lambracos, Srinivasa R Vallabhaneni, Stewart Walsh, Tasleem Aktar, Tony Moloney, Zola Mzimba, Isaac Nyamekye,

OBJECTIVES:Venous thromboembolism is a potentially fatal complication of superficial endovenous treatment. Proper risk assessment and thromboprophylaxis could mitigate this hazard; however, there are currently no evidence-based or consensus guidelines. This study surveyed UK and Republic of Ireland vascular consultants to determine areas of consensus. METHODS:A 32-item survey was sent to ... Read more >>

Phlebology (Phlebology)
[2020, 35(9):706-714]

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Pigmented villonodular synovitis of the hip joint: Three cases demonstrating characteristic MRI features.

Charles J Sullivan, Stephen J Eustace, Eoin C Kavanagh,

Pigmented villonodular synovitis is a rare benign proliferative disease of synovial membranes, causing villonodular synovial hyperplasia and hemosiderin deposition. Its intra-articular forms most commonly affect the knee and less commonly the hip. PVNS of the hip is most common in the second to fifth decades and presentation is typically with ... Read more >>

Radiol Case Rep (Radiology case reports)
[2020, 15(8):1335-1338]

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Multimodal imaging of Spina Ventosa (TB Dactylitis) of the foot.

Mark C Murphy, Alexandra N Murphy, Hannah Hughes, Owen J McEneaney, Conor O'Keane, Eoin Kavanagh,

We present the case of a 29-year-old male healthcare worker with a 6 month history of progressive left foot pain resulting in presentation to the emergency department on 3 occasions. He denied systemic symptoms. Multimodal imaging demonstrated an expansile erosive inflammatory lesion centered on the neck of the second metatarsal ... Read more >>

Radiol Case Rep (Radiology case reports)
[2020, 15(8):1373-1376]

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User-Centered Design for Promoting Patient Engagement in Chronic Diseases Management: The Development of CONCERTO.

Marie-Pierre Gagnon, Mame-Awa Ndiaye, Alain Larouche, Guylaine Chabot, Christian Chabot, Ronald Buyl, Jean-Paul Fortin, Anik Giguère, Annie Leblanc, France Légaré, Aude Motulsky, Claude Sicotte, Holly O Witteman, Éric Kavanagh, Frédéric Lépinay, Jacynthe Roberge, Hina Hakim, Myriam Brunet-Gauthier, Carole Délétroz, Samira A Rahimi, Jack Tchuente, Maxime Sasseville,

Multimorbidity increases care needs among people with chronic diseases. In order to support communication between patients, their informal caregivers and their healthcare teams, we developed CONCERTO+, a patient portal for chronic disease management in primary care. A user-centered design comprising 3 iterations with patients and informal caregivers was performed. Clinicians ... Read more >>

Stud Health Technol Inform (Studies in health technology and informatics)
[2020, 270:1423-1424]

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Gaelic Sport Injuries.

Charles J Sullivan, Eoin C Kavanagh, Stephen J Eustace,

The Gaelic sports of hurling and football, native to Ireland, are increasing in popularity worldwide. The injury profile of these sports requires multidisciplinary management by sports physicians, orthopaedic surgeons, and musculoskeletal (MSK) radiologists, among others. Advances in imaging modalities and interventional techniques have aided the diagnosis and treatment of sport ... Read more >>

Semin Musculoskelet Radiol (Seminars in musculoskeletal radiology)
[2020, 24(3):214-226]

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Chimpanzee lip-smacks confirm primate continuity for speech-rhythm evolution.

André S Pereira, Eithne Kavanagh, Catherine Hobaiter, Katie E Slocombe, Adriano R Lameira,

Speech is a human hallmark, but its evolutionary origins continue to defy scientific explanation. Recently, the open-close mouth rhythm of 2-7 Hz (cycles/second) characteristic of all spoken languages has been identified in the orofacial signals of several nonhuman primate genera, including orangutans, but evidence from any of the African apes ... Read more >>

Biol Lett (Biology letters)
[2020, 16(5):20200232]

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Autologous bone marrow mesenchymal stromal cell therapy for "no-option" critical limb ischemia is limited by karyotype abnormalities.

Sara Azhari Mohamed, Linda Howard, Veronica McInerney, Amjad Hayat, Janusz Krawczyk, Sean Naughton, Andrew Finnerty, Miriam Holohan, Aoife Duffy, Tony Moloney, Eamon Kavanagh, Paul Burke, Aaron Liew, Muhammad Tubassam, Stewart Redmond Walsh, Timothy O'Brien,

BACKGROUND:Critical limb ischemia (CLI) is the most severe manifestation of peripheral vascular disease. Revascularization is the preferred therapy, but it is not achievable in 25%-40% of patients due to diffuse anatomic distribution of the disease or medical comorbidities. No-option CLI represents an unmet medical need. Mesenchymal stromal cells (MSCs) may ... Read more >>

Cytotherapy (Cytotherapy)
[2020, 22(6):313-321]

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Our Experience with Radiology Podcasts, an Exciting Addition to Contemporary Radiology Literature.

John Hynes, Mark Murphy, Ciara Gillespie, Eoin Kavanagh,

Radiology (Radiology)
[2020, 295(1):247]

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Subperiosteal hematoma of the iliac wing presenting with leg weakness in a young adult footballer.

John P Hynes, Richard E Downey, Nicola Hughes, Conor J O'Keane, Eoin Kavanagh,

We present the case of a 17 year old football player with a 2 week history of left leg weakness and difficulty weight-bearing. Magnetic resonance imaging revealed a well-circumscribed lesion deep to the left iliacus muscle. The patient proceeded to computed tomography-guided biopsy. The likely diagnosis was that of a ... Read more >>

Radiol Case Rep (Radiology case reports)
[2020, 15(4):424-426]

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The effect of Instagram #fitspiration images on young women's mood, body image, and exercise behaviour.

Ivanka Prichard, Eliza Kavanagh, Kate E Mulgrew, Megan S C Lim, Marika Tiggemann,

The present study experimentally examined the effects of viewing Instagram images of fitspiration on body dissatisfaction, mood, and exercise behaviour among young women. Further, the study investigated if exercise engagement following exposure to fitspiration images could mitigate any negative effects from image exposure. Participants were 108 women, aged 17-25 years, ... Read more >>

Body Image (Body image)
[2020, 33:1-6]

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