Full Text Journal Articles by
Author E Anne MacGregor

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Menstrual migraine: a distinct disorder needing greater recognition.

Kjersti Grøtta Vetvik, E Anne MacGregor,

The term menstrual migraine refers to migraine that is associated with menstruation by more than chance, but it does not define pathophysiology. Menstrual migraine affects about 20-25% of female migraineurs in the general population, and 22-70% of patients presenting to headache clinics. In women diagnosed with menstrual migraine, perimenstrual migraine ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2021, :]

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Current clinical practice in disabling and chronic migraine in the primary care setting: results from the European My-LIFE anamnesis survey.

Philippe Ryvlin, Kirill Skorobogatykh, Andrea Negro, Rainel Sanchez-De La Rosa, Heike Israel-Willner, Christina Sundal, E Anne MacGregor, Angel L Guerrero,

<h4>Background</h4>Migraine is a prevalent and disabling headache disorder that affects more than 1.04 billion individuals world-wide. It can result in reduction in quality of life, increased disability, and high socio-economic burden. Nevertheless, and despite the availability of evidence-based national and international guidelines, the management of migraine patients often remains suboptimal, ... Read more >>

BMC Neurol (BMC neurology)
[2021, 21(1):1]

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Menstrual and perimenopausal migraine: A narrative review.

E Anne MacGregor,

Migraine is affected by the changing hormone environment, with perimenopause associated with increased migraine, particularly menstrual migraine. Menstrual attacks are recognised to be more disabling and less responsive to treatment compared with non-menstrual attacks. Perimenstrual estrogen 'withdrawal' is implicated in the pathophysiology of menstrual migraine, with increased prevalence of migraine ... Read more >>

Maturitas (Maturitas)
[2020, 142:24-30]

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Migraine start, course and features over the cycle of combined hormonal contraceptive users with menstrual migraine - temporal relation to bleeding and hormone withdrawal: a prospective diary-based study.

Gabriele S Merki-Feld, Nina Caveng, Gina Speiermann, E Anne MacGregor,

<h4>Background</h4>Many studies have described the features of menstrually-related migraines (MRM) in the natural cycle and the efficacy of prevention. MRM in combined hormonal contraceptive (CHC) users has scarcely been researched. Estrogen and progestin withdrawal in CHC users are both more abrupt and from higher hormone levels compared with the natural ... Read more >>

J Headache Pain (The journal of headache and pain)
[2020, 21(1):81]

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A Markov chain method for counting and modelling migraine attacks.

Mathias Barra, Fredrik A Dahl, Kjersti Grøtta Vetvik, E Anne MacGregor,

To ensure reproducibility in research quantifying episodic migraine attacks, and identifying attack onset, a sound theoretical model of a migraine attack, paired with a uniform standard for counting them, is necessary. Many studies report on migraine frequencies-e.g. the fraction of migraine-days of the observed days-without paying attention to the number ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):3631]

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Migraine, low-dose combined hormonal contraceptives, and ischemic stroke in young women: a systematic review and suggestions for future research.

Raffaele Ornello, Marianne Canonico, Gabriele S Merki-Feld, Tobias Kurth, Øjvind Lidegaard, E Anne MacGregor, Christian Lampl, Rossella Elena Nappi, Paolo Martelletti, Simona Sacco,

Introduction: Migraine and combined hormonal contraceptives (CHCs) increase the risk of ischemic stroke in young women; however, the contribution of low-dose (<50 μg ethinylestradiol) CHCs to the risk of ischemic stroke in young women with migraine is not well defined.Areas covered: The authors performed a systematic review of observational studies indexed ... Read more >>

Expert Rev Neurother (Expert review of neurotherapeutics)
[2020, 20(4):313-317]

Cited: 1 time

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Identifying menstrual migraine- improving the diagnostic criteria using a statistical method.

Mathias Barra, Fredrik A Dahl, E Anne MacGregor, Kjersti Grøtta Vetvik,

OBJECTIVE:To develop a robust statistical tool for the diagnosis of menstrually related migraine. BACKGROUND:The International Classification of Headache Disorders (ICHD) has diagnostic criteria for menstrual migraine within the appendix. These include the requirement for menstrual attacks to occur within a 5-day window in at least [Formula: see text] menstrual cycles ... Read more >>

J Headache Pain (The journal of headache and pain)
[2019, 20(1):95]

Cited: 2 times

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Effect of exogenous estrogens and progestogens on the course of migraine during reproductive age: a consensus statement by the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESCRH).

Simona Sacco, Gabriele S Merki-Feld, Karen Lehrmann Ægidius, Johannes Bitzer, Marianne Canonico, Andreas R Gantenbein, Tobias Kurth, Christian Lampl, Øjvind Lidegaard, E Anne MacGregor, Antoinette MaassenVanDenBrink, Dimos-Dimitrios Mitsikostas, Rossella Elena Nappi, George Ntaios, Koen Paemeleire, Per Morten Sandset, Gisela Marie Terwindt, Kjersti Grøtta Vetvik, Paolo Martelletti, ,

We systematically reviewed data about the effect of exogenous estrogens and progestogens on the course of migraine during reproductive age. Thereafter a consensus procedure among international experts was undertaken to develop statements to support clinical decision making, in terms of possible effects on migraine course of exogenous estrogens and progestogens ... Read more >>

J Headache Pain (The journal of headache and pain)
[2018, 19(1):76]

Cited: 3 times

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Symptoms of premenstrual syndrome in female migraineurs with and without menstrual migraine.

Kjersti Grøtta Vetvik, E Anne MacGregor, Christofer Lundqvist, Michael Bjørn Russell,

<h4>Background</h4>Menstrual migraine (MM) and premenstrual syndrome (PMS) are two conditions linked to specific phases of the menstrual cycle. The exact pathophysiological mechanisms are not fully understood, but both conditions are hypothesized to be triggered by female sex hormones. Co-occurrence of MM and PMS is controversial. The objective of this population-based ... Read more >>

J Headache Pain (The journal of headache and pain)
[2018, 19(1):97]

Cited: 3 times

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Correction to: Hormonal contraceptives and risk of ischemic stroke in women with migraine: a consensus statement from the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC).

Simona Sacco, Gabriele S Merki-Feld, Karen Lehrmann Ægidius, Johannes Bitzer, Marianne Canonico, Tobias Kurth, Christian Lampl, Øjvind Lidegaard, E Anne MacGregor, Antoinette MaassenVanDenBrink, Dimos-Dimitrios Mitsikostas, Rossella Elena Nappi, George Ntaios, Per Morten Sandset, Paolo Martelletti, ,

Following the publication of this article [1], the authors noticed that they incorrectly reported the Absolute risk of ischemic stroke in women aged 20 to 44 years in relation to the use of hormonal contraception and migraine status due to a miscalculation. They apologize for this misreported result. ... Read more >>

J Headache Pain (The journal of headache and pain)
[2018, 19(1):81]

Cited: 0 times

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The 7-day contraceptive hormone-free interval should be consigned to history.

E Anne MacGregor, John Guillebaud,

<h4>Aim</h4>This review summarises the available data on the disadvantages of the 7-day contraceptive-free interval (CFI) of combined oral contraceptives (COCs), in contrast to shorter CFIs or continuous use - including flexible regimens - and provides recommendations for practice.<h4>Methods</h4>Relevant papers were identified by Medline and PubMed. The final reference list was ... Read more >>

BMJ Sex Reprod Health (BMJ sexual & reproductive health)
[2018, :]

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The NRP1 migraine risk variant shows evidence of association with menstrual migraine.

Charmaine E Pollock, Heidi G Sutherland, Bridget H Maher, Rodney A Lea, Larisa M Haupt, Alison Frith, E Anne MacGregor, Lyn R Griffiths,

In 2016, a large meta-analysis brought the number of susceptibility loci for migraine to 38. While sub-type analysis for migraine without aura (MO) and migraine with aura (MA) found some loci showed specificity to MO, the study did not test the loci with respect to other subtypes of migraine. This ... Read more >>

J Headache Pain (The journal of headache and pain)
[2018, 19(1):31]

Cited: 2 times

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Migraine, menopause and hormone replacement therapy.

E Anne MacGregor,

Perimenopause marks a period of increased migraine prevalence in women and many women also report troublesome vasomotor symptoms. Migraine is affected by fluctuating estrogen levels with evidence to support estrogen 'withdrawal' as a trigger of menstrual attacks of migraine without aura, while high estrogen levels can trigger migraine aura. Maintaining ... Read more >>

Post Reprod Health (Post reproductive health)
[2018, 24(1):11-18]

Cited: 5 times

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Hormonal contraceptives and risk of ischemic stroke in women with migraine: a consensus statement from the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC).

Simona Sacco, Gabriele S Merki-Feld, Karen Lehrmann Ægidius, Johannes Bitzer, Marianne Canonico, Tobias Kurth, Christian Lampl, Øjvind Lidegaard, E Anne MacGregor, Antoinette MaassenVanDenBrink, Dimos-Dimitrios Mitsikostas, Rossella Elena Nappi, George Ntaios, Per Morten Sandset, Paolo Martelletti, ,

Several data indicate that migraine, especially migraine with aura, is associated with an increased risk of ischemic stroke and other vascular events. Of concern is whether the risk of ischemic stroke in migraineurs is magnified by the use of hormonal contraceptives. As migraine prevalence is high in women of reproductive ... Read more >>

J Headache Pain (The journal of headache and pain)
[2017, 18(1):108]

Cited: 23 times

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Migraine (Japanese Version).

E Anne MacGregor,

Ann Intern Med (Annals of internal medicine)
[2017, 166(7):JITC49-JITC64]

Cited: 0 times

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Sex differences in the epidemiology, clinical features, and pathophysiology of migraine.

Kjersti Grøtta Vetvik, E Anne MacGregor,

Migraine is two to three times more prevalent in women than men, and women report a longer attack duration, increased risk of headache recurrence, greater disability, and a longer period of time required to recover. Conditions recognised to be comorbid with migraine include asthma, anxiety, depression, and other chronic pain ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2017, 16(1):76-87]

Cited: 83 times

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Migraine.

E Anne MacGregor,

This issue provides a clinical overview of migraine, focusing on risk, prevention, diagnosis, treatment, follow-up, and practice improvement. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2017, 166(7):ITC49-ITC64]

Cited: 9 times

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Investigation of polymorphisms in genes involved in estrogen metabolism in menstrual migraine.

Heidi G Sutherland, Morgane Champion, Amelie Plays, Shani Stuart, Larisa M Haupt, Alison Frith, E Anne MacGregor, Lyn R Griffiths,

Migraine is a common, disabling headache disorder, which is influenced by multiple genes and environmental triggers. After puberty, the prevalence of migraine in women is three times higher than in men and >50% of females suffering from migraine report a menstrual association, suggesting hormonal fluctuations can influence the risk of ... Read more >>

Gene (Gene)
[2017, 607:36-40]

Cited: 3 times

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The role of methysergide in migraine and cluster headache treatment worldwide - A survey in members of the International Headache Society.

E Anne MacGregor, Stefan Evers, ,

Background Methysergide has been as an effective treatment for migraine and cluster headache for over 50 years but has recently been investigated by the European Medicines Agency due to safety concerns. Methods To assess the need for continuing availability of methysergide, the International Headache Society performed an electronic survey among ... Read more >>

Cephalalgia (Cephalalgia : an international journal of headache)
[2017, 37(11):1106-1108]

Cited: 5 times

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Diagnosing migraine.

E Anne MacGregor,

Migraine is a common headache disorder, particularly in women. It usually starts during the teens and twenties, a time when many women are seeking contraception advice. Migraine without aura is the most prevalent type of migraine, affecting up to 70% of people with migraine, while the remainder experience attacks with ... Read more >>

J Fam Plann Reprod Health Care (The journal of family planning and reproductive health care)
[2016, 42(4):280-286]

Cited: 3 times

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Migraine Management During Menstruation and Menopause.

E Anne MacGregor,

<h4>Purpose of review</h4>Migraine is most prevalent in women during their reproductive years. An understanding of the effects of menstruation and menopause on migraine can enable neurologists to provide targeted and appropriate medical and hormonal strategies, enabling their patients to achieve better control of migraine and reduced disability. This article reviews ... Read more >>

Continuum (Minneap Minn) (Continuum (Minneapolis, Minn.))
[2015, 21(4 Headache):990-1003]

Cited: 4 times

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Randomized controlled trial of the CGRP receptor antagonist telcagepant for prevention of headache in women with perimenstrual migraine.

Tony W Ho, Andrew P Ho, Yang Joy Ge, Christopher Assaid, Regina Gottwald, E Anne MacGregor, Lisa K Mannix, Willebrordus P J van Oosterhout, Janelle Koppenhaver, Christopher Lines, Michel D Ferrari, David Michelson,

<h4>Aim</h4>The aim of this article is to evaluate the safety and efficacy of perimenstrual telcagepant, a CGRP receptor antagonist, for headache prophylaxis.<h4>Methods</h4>We conducted a randomized, double-blind, placebo-controlled, six-month trial in women with migraine for ≥ 3 months who experienced perimenstrual headaches. Women were randomized to telcagepant 140 mg or placebo ... Read more >>

Cephalalgia (Cephalalgia : an international journal of headache)
[2016, 36(2):148-161]

Cited: 26 times

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A clinical interview versus prospective headache diaries in the diagnosis of menstrual migraine without aura.

Kjersti G Vetvik, E Anne MacGregor, Christofer Lundqvist, Michael B Russell,

<h4>Objectives</h4>The objective of this article is to compare the diagnosis of menstrual migraine without aura (MM) from a clinical interview with prospective headache diaries in a population-based study.<h4>Material and methods</h4>A total of 237 women with self-reported migraine in at least half of menstruations were interviewed by a neurologist about headache ... Read more >>

Cephalalgia (Cephalalgia : an international journal of headache)
[2015, 35(5):410-416]

Cited: 2 times

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Menstrual versus non-menstrual attacks of migraine without aura in women with and without menstrual migraine.

Kjersti Grøtta Vetvik, Jūratė Šaltytė Benth, E Anne MacGregor, Christofer Lundqvist, Michael Bjørn Russell,

<h4>Objective</h4>The objective of this article is to compare clinical characteristics of menstrual and non-menstrual attacks of migraine without aura (MO), prospectively recorded in a headache diary, by women with and without a diagnosis of menstrual migraine without aura (MM) according to the International Classification of Headache Disorders (ICHD).<h4>Material and methods</h4>A ... Read more >>

Cephalalgia (Cephalalgia : an international journal of headache)
[2015, 35(14):1261-1268]

Cited: 12 times

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Genetic association and gene expression studies suggest that genetic variants in the SYNE1 and TNF genes are related to menstrual migraine.

Astrid J Rodriguez-Acevedo, Robert A Smith, Bishakha Roy, Heidi Sutherland, Rod A Lea, Alison Frith, E Anne MacGregor, Lyn R Griffiths,

Menstrual migraine (MM) encompasses pure menstrual migraine (PMM) and menstrually-related migraine (MRM). This study was aimed at investigating genetic variants that are potentially related to MM, specifically undertaking genotyping and mRNA expression analysis of the ESR1, PGR, SYNE1 and TNF genes in MM cases and non-migraine controls.A total of 37 ... Read more >>

J Headache Pain (The journal of headache and pain)
[2014, 15:62]

Cited: 5 times

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