Full Text Journal Articles by
Author Douglas Y Mah

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Clinical and Genetic Findings in Children Presenting With Ventricular Fibrillation as the First Manifestation of Cardiovascular Disease.

Robyn J Hylind, Stephanie F Chandler, Virginie Beausejour Ladouceur, Shelina M Jamal, Mark E Alexander, Douglas Y Mah, Emily A Phaneuf, Elizabeth S DeWitt, Vassilios J Bezzerides, Dominic J Abrams,

J Am Heart Assoc (Journal of the American Heart Association)
[2020, 9(10):e016322]

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Value of provocative electrophysiology testing in the management of pediatric patients after congenital heart surgery.

Audrey Dionne, John N Kheir, Kimberlee Gauvreau, John K Triedman, Dominic J Abrams, Mark E Alexander, Elizabeth S DeWitt, Douglas Y Mah, Edward P Walsh, Vassilios J Bezzerides,

OBJECTIVE:To determine the impact of provocative electrophysiology testing in post-operative congenital heart disease (CHD) patients on the management of supraventricular tachycardia (SVT) and clinical outcomes. METHODS:This is a retrospective study including patients < 18 years of age with surgery for CHD who had post-operative SVT between 2006-2017. Post-operative outcomes were ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2020, :]

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Adverse event rate during inpatient sotalol initiation for the management of supraventricular and ventricular tachycardia in the pediatric and young adult population.

Stephanie F Chandler, Esther Chu, Robert D Whitehill, Laura M Bevilacqua, Vassilios J Bezzerides, Elizabeth S DeWitt, Mark E Alexander, Dominic J Abrams, John K Triedman, Edward P Walsh, Douglas Y Mah,

BACKGROUND:Sotalol is an important antiarrhythmic drug in the pediatric population. Given the risk of proarrhythmia, sotalol is initiated in inpatient settings, with adult studies as recent as 2015 supporting this practice. OBJECTIVE:The purpose of this study was to determine the frequency of adverse events (AEs) during sotalol initiation for the ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, 17(6):984-990]

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Ultra-rapid atrial pacing as a form of rate control in postoperative automatic arrhythmias in patients with congenital heart disease.

Stephanie F Chandler, Robert D Whitehill, Elizabeth S DeWitt, Mark E Alexander, Francis Fynn Thompson, Douglas Y Mah,

HeartRhythm Case Rep (HeartRhythm case reports)
[2020, 6(4):215-218]

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Low mortality in fetal supraventricular tachycardia: Outcomes in a 30-year single-institution experience.

Edward T O'Leary, Mark E Alexander, Vassilios J Bezzerides, Monika Drogosz, Katherine E Economy, Kevin G Friedman, Sarah S Pickard, Wayne Tworetzky, Douglas Y Mah,

OBJECTIVES:To describe a single institutional experience managing fetuses with supraventricular tachycardia (SVT) and to identify associations between patient characteristics and fetal and postnatal outcomes. BACKGROUND:Sustained fetal SVT is associated with significant morbidity and mortality if untreated, yet the optimal management strategy remains unclear. METHODS:Retrospective cohort study including fetuses diagnosed with ... Read more >>

J. Cardiovasc. Electrophysiol. (Journal of cardiovascular electrophysiology)
[2020, 31(5):1105-1113]

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Outcomes of catheter ablation of anteroseptal and midseptal accessory pathways in pediatric patients.

Joshua R Kovach, Douglas Y Mah, Dominic J Abrams, Mark E Alexander, Frank Cecchin, John K Triedman, Edward P Walsh,

BACKGROUND:Outcomes for catheter ablation of accessory pathways in pediatric patients have steadily improved, with the exception of pathways located in the anteroseptal (AS) and midseptal (MS) regions, where success is limited by the close proximity of normal atrioventricular conduction. OBJECTIVE:The purpose of this study was to evaluate the efficacy of ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, 17(5 Pt A):759-767]

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Implanted pacemaker and cardioverter-defibrillator in a patient with ectopia cordis.

Tam Dan N Pham, Anne-Marie Valente, John E Mayer, Elizabeth S DeWitt, Douglas Y Mah,

HeartRhythm Case Rep (HeartRhythm case reports)
[2020, 6(2):110-113]

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Successful bilateral thoracoscopic sympathectomy for recurrent ventricular arrhythmia in a pediatric patient with hypertrophic cardiomyopathy.

Joshua Price, Douglas Y Mah, Francis L Fynn-Thompson, Anna E Tsirka,

HeartRhythm Case Rep (HeartRhythm case reports)
[2020, 6(1):23-26]

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Acute coronary artery obstruction following surgical repair of congenital heart disease.

Michael P Goldsmith, Catherine K Allan, Ryan Callahan, Aditya K Kaza, Douglas Y Mah, Joshua W Salvin, Kimberlee Gauvreau, Diego Porras,

OBJECTIVES:Acute coronary artery obstruction is a rare complication of congenital heart disease surgery but imposes a high burden of morbidity and mortality. Previous case series have described episodes in specific congenital heart lesions or surgical repairs but have not examined the complication in all-comers to congenital heart surgery. We hypothesize ... Read more >>

J. Thorac. Cardiovasc. Surg. (The Journal of thoracic and cardiovascular surgery)
[2020, 159(5):1957-1965.e1]

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Riata lead failure in pediatric and congenital heart disease patients.

Carolina A Escudero, Douglas Y Mah, Christina Y Miyake, Elizabeth A Stephenson, Martin J LaPage, Peter Kubuš, Mitchell I Cohen, Joseph Atallah,

BACKGROUND:Implantable cardioverter defibrillator (ICD) lead failures occur at higher rates in pediatric and congenital heart disease (CHD) patients. OBJECTIVE:To determine the rate and timing of Riata lead failure in pediatric and CHD patients. METHODS:This was a retrospective, multicenter cohort study of pediatric patients and adults with CHD with implantation of ... Read more >>

J. Cardiovasc. Electrophysiol. (Journal of cardiovascular electrophysiology)
[2019, 30(3):320-325]

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Differentiation of fasciculoventricular fibers from anteroseptal accessory pathways using the surface electrocardiogram.

Edward T O'Leary, Elizabeth S Dewitt, Douglas Y Mah, Kimberlee Gauvreau, Edward P Walsh, Vassilios J Bezzerides,

BACKGROUND:Fasciculoventricular fibers (FVFs) are responsible for 1%-5% of cases of asymptomatic preexcitation on the surface electrocardiogram (ECG). Unlike ventricular preexcitation seen in Wolff-Parkinson-White (WPW) syndrome, FVFs are not associated with sudden cardiac death from preexcited atrial fibrillation. OBJECTIVE:The purpose of this study was to identify surface ECG variables that differentiate ... Read more >>

Heart Rhythm (Heart rhythm)
[2019, 16(7):1072-1079]

Cited: 1 time

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The Real-World Utility of the LINQ Implantable Loop Recorder in Pediatric and Adult Congenital Heart Patients.

Vassilios J Bezzerides, Amy Walsh, Maria Martuscello, Carolina A Escudero, Kimberlee Gauvreau, Geralyn Lam, Dominic J Abrams, John K Triedman, Mark E Alexander, Laura Bevilacqua, Douglas Y Mah,

OBJECTIVES:This study sought to determine the practical use of the recently introduced LINQ implantable loop recorder (LINQ-ILR) in a cohort of pediatric and adult congenital arrhythmia patients. BACKGROUND:Correlating symptoms to a causative arrhythmia is a key aspect of diagnosis and management in clinical electrophysiology. METHODS:Retrospective review of clinical data, implantation ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2019, 5(2):245-251]

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Evaluation of left ventricular false tendons in children with idiopathic left ventricular tachycardia.

Anthony Merlocco, David W Brown, Kimberlee Gauvreau, Douglas Y Mah, John K Triedman, Mark E Alexander, Edward P Walsh,

BACKGROUND:Left ventricular false tendons (FT) traverse the ventricular cavity and are thought to have some association with idiopathic left ventricular tachycardia (ILVT). However, reported prevalence of FT varies widely, making correlation difficult. Superior echocardiographic windows of pediatric patients may permit better analysis of FT in ILVT. Our study describes the ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2018, 41(9):1143-1149]

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Frequency of Ventricular Arrhythmias and Other Rhythm Abnormalities in Children and Young Adults With the Marfan Syndrome.

Douglas Y Mah, Lynn A Sleeper, Jane E Crosson, Richard J Czosek, Barry A Love, Brian W McCrindle, Laura Muiño-Mosquera, Aaron K Olson, Thomas A Pilcher, Elif Seda Selamet Tierney, Maully J Shah, Stephanie B Wechsler, Luciana T Young, Ronald V Lacro,

Patients with the Marfan syndrome (MFS) are at risk for sudden death. The contribution of arrhythmias is unclear. This study examines the prevalence of arrhythmias in children with the MFS and their relation to clinical and/or echocardiographic factors. Data from the Pediatric Heart Network randomized trial of atenolol versus losartan ... Read more >>

Am. J. Cardiol. (The American journal of cardiology)
[2018, 122(8):1429-1436]

Cited: 1 time

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Dual-Site Ventricular Pacing in Patients With Fontan Physiology and Heart Block: Does it Mitigate the Detrimental Effects of Single-Site Ventricular Pacing?

Edward T O'Leary, Kimberlee Gauvreau, Mark E Alexander, Puja Banka, Vassilios J Bezzerides, Francis Fynn-Thompson, John K Triedman, Edward P Walsh, Douglas Y Mah,

OBJECTIVES:This study sought to determine the long-term effect of dual-site ventricular pacing (i.e., cardiac resynchronization therapy [CRT]) versus single-site pacing in patients with Fontan physiology and high-grade atrioventricular block (AVB). BACKGROUND:Chronic single-site ventricular pacing in Fontan patients is associated with significant morbidity and mortality. METHODS:The study conducted a retrospective review ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2018, 4(10):1289-1297]

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Coronary artery compression from epicardial leads: More common than we think.

Douglas Y Mah, Ashwin Prakash, Diego Porras, Francis Fynn-Thompson, Elizabeth S DeWitt, Puja Banka,

BACKGROUND:A child with an epicardial pacemaker presented with sudden death at our institution, secondary to coronary artery compression. This case prompted enhanced surveillance of all patients with epicardial pacing or defibrillation systems. OBJECTIVE:The purpose of this study was to determine the incidence of coronary artery compression and the diagnostic yield ... Read more >>

Heart Rhythm (Heart rhythm)
[2018, 15(10):1439-1447]

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Role of cardiac pacing in congenital complete heart block.

Stephanie F Chandler, Francis Fynn-Thompson, Douglas Y Mah,

Congenital complete heart block affects 1/15,000 live-born infants, predominantly due to atrioventricular nodal injury from maternal antibodies of mothers with systemic lupus erythermatosus or Sjogren's syndrome. The majority of these children will need a pacemaker implanted prior to becoming young adults. This article will review the various patient and technical ... Read more >>

Expert Rev Cardiovasc Ther (Expert review of cardiovascular therapy)
[2017, 15(11):853-861]

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Cardiac Events During Competitive, Recreational, and Daily Activities in Children and Adolescents With Long QT Syndrome.

Kristina D Chambers, Virginie Beausejour Ladouceur, Mark E Alexander, Robyn J Hylind, Laura Bevilacqua, Douglas Y Mah, Vassilios Bezzerides, John K Triedman, Edward P Walsh, Dominic J Abrams,

The 2005 Bethesda Conference Guidelines advise patients with long QT syndrome against competitive sports. We assessed cardiac event rates during competitive and recreational sports, and daily activities among treated long QT syndrome patients.Long QT syndrome patients aged ≥4 years treated with anti-adrenergic therapy were included. Demographics included mechanism of presentation, corrected ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2017, 6(9):]

Cited: 1 time

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Relation of Left Atrial Size to Atrial Fibrillation in Patients Aged ≤22 Years.

Douglas Y Mah, Divya Shakti, Kimberlee Gauvreau, Steven D Colan, Mark E Alexander, Dominic J Abrams, David W Brown,

Left atrial (LA) dilation has been shown to be associated with atrial fibrillation (AF) in the adult population, with some studies indicating that larger LAs are more prone to AF recurrence. The relation of LA size to AF in the pediatric and young adult population has not been investigated. In ... Read more >>

Am. J. Cardiol. (The American journal of cardiology)
[2017, 119(1):52-56]

Cited: 1 time

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Evaluation of the fetal QT interval using non-invasive fetal ECG technology.

Joachim Behar, Tingting Zhu, Julien Oster, Alisa Niksch, Douglas Y Mah, Terrence Chun, James Greenberg, Cassandre Tanner, Jessica Harrop, Reza Sameni, Jay Ward, Adam J Wolfberg, Gari D Clifford,

Non-invasive fetal electrocardiography (NI-FECG) is a promising alternative continuous fetal monitoring method that has the potential to allow morphological analysis of the FECG. However, there are a number of challenges associated with the evaluation of morphological parameters from the NI-FECG, including low signal to noise ratio of the NI-FECG and ... Read more >>

Physiol Meas (Physiological measurement)
[2016, 37(9):1392-1403]

Cited: 5 times

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Heart block following stage 1 palliation of hypoplastic left heart syndrome.

Douglas Y Mah, Henry Cheng, Mark E Alexander, Lynn Sleeper, Jane W Newburger, Pedro J Del Nido, Ravi R Thiagarajan, Satish K Rajagopal,

Publicly available data from the Pediatric Heart Network's Single Ventricle Reconstruction Trial was analyzed to determine the prevalence, timing, risk factors for, and impact of second- and third-degree heart block (HB) on outcomes in patients who underwent stage 1 palliation (S1P) for hypoplastic left heart syndrome (HLHS).The presence and date ... Read more >>

J. Thorac. Cardiovasc. Surg. (The Journal of thoracic and cardiovascular surgery)
[2016, 152(1):189-194]

Cited: 5 times

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Impact of pacing on systemic ventricular function in L-transposition of the great arteries.

Sophie C Hofferberth, Mark E Alexander, Douglas Y Mah, Victor Bautista-Hernandez, Pedro J del Nido, Francis Fynn-Thompson,

To assess the impact of univentricular versus biventricular pacing (BiVP) on systemic ventricular function in patients with congenitally corrected transposition of the great arteries (ccTGA).We performed a retrospective review of all patients with a diagnosis of ccTGA who underwent pacemaker insertion. From 1993 to 2014, 53 patients were identified from ... Read more >>

J. Thorac. Cardiovasc. Surg. (The Journal of thoracic and cardiovascular surgery)
[2016, 151(1):131-138]

Cited: 9 times

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Mechanism and ablation of arrhythmia following total cavopulmonary connection.

Rafael Correa, Elizabeth D Sherwin, Joshua Kovach, Douglas Y Mah, Mark E Alexander, Frank Cecchin, Edward P Walsh, John K Triedman, Dominic J Abrams,

BACKGROUND: The ability to identify and ablate different arrhythmia mechanisms after the total cavopulmonary connection has not been studied in detail. METHODS AND RESULTS: After obtaining Institutional Review Board approval according to institutional guidelines, consecutive patients after a total cavopulmonary connection undergoing electrophysiology study over a 6-year period were included ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2015, 8(2):318-325]

Cited: 23 times

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Perinatal outcome in fetuses with heterotaxy syndrome and atrioventricular block or bradycardia.

Maria C Escobar-Diaz, Wayne Tworetzky, Kevin Friedman, Terra Lafranchi, Francis Fynn-Thompson, Mark E Alexander, Douglas Y Mah,

Congenital atrioventricular (AV) block is commonly associated with heterotaxy syndrome; together they have reportedly low survival rates (10-25%). However, information about perinatal outcome and predictors of non-survival after prenatal diagnosis of this association is scarce. Therefore, we studied fetuses with heterotaxy syndrome and bradycardia or AV-block diagnosed between 1995 and ... Read more >>

Pediatr Cardiol (Pediatric cardiology)
[2014, 35(6):906-913]

Cited: 5 times

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Incidence of and risk factors for catheterization-induced complete heart block in the pediatric cardiac catheterization laboratory.

Douglas Y Mah, Diego Porras, Lisa Bergersen, Audrey C Marshall, Edward P Walsh, John K Triedman,

BACKGROUND: The majority of the literature on catheterization-induced heart block (CIHB) was published >30 years ago. The field of cardiac catheterization has evolved, performing more interventional compared with diagnostic cases. We sought to determine the incidence and risk factors of CIHB. METHODS AND RESULTS: A catheterization database that records the ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2014, 7(1):127-133]

Cited: 4 times

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