Full Text Journal Articles by
Author Douglas O Fleming


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Nicotine replacement therapy sampling via primary care: Methods from a pragmatic cluster randomized clinical trial.

Jennifer Dahne, Amy E Wahlquist, Amy S Boatright, Elizabeth Garrett-Mayer, Douglas O Fleming, Robert Davis, Brent Egan, Matthew J Carpenter,

BACKGROUND:Primary care is the most important point of healthcare contact for smokers. Brief physician advice to quit, based on the 5As/AAR model, offers some efficacy but is inconsistently administered and has limited population impact. Nicotine replacement therapy (NRT) sampling, defined as provision of a brief NRT starter kit, when added ... Read more >>

Contemp Clin Trials (Contemporary clinical trials)
[2018, 72:1-7]

Cited: 1 time

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2013 ACC/AHA Cholesterol Guideline and Implications for Healthy People 2020 Cardiovascular Disease Prevention Goals.

Brent M Egan, Jiexiang Li, Kellee White, Douglas O Fleming, Kenneth Connell, German T Hernandez, Daniel W Jones, Keith C Ferdinand, Angelo Sinopoli,

Healthy People 2020 aim to reduce fatal atherosclerotic cardiovascular disease (ASCVD) by 20%, which translates into 310 000 fewer events annually assuming proportional reduction in fatal and nonfatal ASCVD. We estimated preventable ASCVD events by implementing the American College of Cardiology/American Heart Association (ACC/AHA) 2013 Cholesterol Guideline in all statin-eligible adults. ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2016, 5(8):]

Cited: 14 times

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Low Blood Pressure Is Associated With Greater Risk for Cardiovascular Events in Treated Adults With and Without Apparent Treatment-Resistant Hypertension.

Brent M Egan, Bo Kai, C Shaun Wagner, Douglas O Fleming, Joseph H Henderson, Archie H Chandler, Angelo Sinopoli,

Apparent treatment-resistant hypertension (aTRH) may confound the reported relationship between low blood pressure (BP) and increased cardiovascular disease (CVD) in treated hypertensive patients. Incident CVD was assessed in treated hypertensive patients with and without aTRH (BP ≥140 and/or ≥90 mm Hg on ≥3 medications or <140/<90 mm Hg on ≥4 ... Read more >>

J Clin Hypertens (Greenwich) (Journal of clinical hypertension (Greenwich, Conn.))
[2017, 19(3):241-249]

Cited: 4 times

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Aldosterone Antagonists or Renin-Guided Therapy for Treatment-Resistant Hypertension: A Comparative Effectiveness Pilot Study in Primary Care.

Brent M Egan, Marilyn A Laken, Susan E Sutherland, Suparna Qanungo, Douglas O Fleming, Anne G Cook, William H Hester, Kelly W Jones, Gerard C Jebaily, Gregory T Valainis, Charles F Way, Mary Beth Wright, Robert A Davis,

Uncontrolled treatment-resistant hypertension (TRH), i.e., blood pressure (BP, mm Hg) ≥140/≥90mm Hg in and out of office on ≥3 different BP medications at optimal doses, is common and has a poor prognosis. Aldosterone antagonist (AA) and renin-guided therapy (RGT) are effective strategies for improving BP control in TRH but have ... Read more >>

Am. J. Hypertens. (American journal of hypertension)
[2016, 29(8):976-983]

Cited: 1 time

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Impact of Implementing the 2013 ACC/AHA Cholesterol Guidelines on Vascular Events in a Statewide Community-Based Practice Registry.

Brent M Egan, Jiexiang Li, Douglas O Fleming, Kellee White, Kenneth Connell, Robert A Davis, Angelo Sinopoli,

Electronic health record data were analyzed to estimate the number of statin-eligible adults with the 2013 American College of Cardiology/American Heart Association cholesterol guidelines not taking statin therapy and the impact of recommended statin therapy on 10-year atherosclerotic cardiovascular disease (ASCVD10 ) events. Adults aged 21 to 80 years in ... Read more >>

J Clin Hypertens (Greenwich) (Journal of clinical hypertension (Greenwich, Conn.))
[2016, 18(7):663-671]

Cited: 2 times

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