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MicroRNA-378 regulates adipogenic differentiation in bovine intramuscular preadipocytes by targeting CaMKK2.

Dongwei Li, Heng Wang, Yongmin Li, Changqing Qu, Yunhai Zhang, Hongyu Liu, Xiaorong Zhang,

Intramuscular fat, as one of the most important palatability attribute of beef carcase, is the primary determinant of beef quality. The research of adipogenesis mechanism would provide new insight into intramuscular fatty deposition. Here, the role of microRNA-378 was investigated during bovine adipogenic differentiation. It was revealed that miR-378 expression ... Read more >>

Adipocyte (Adipocyte)
[2021, 10(1):483-492]

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Baiting out a full length sequence from unmapped RNA-seq data.

Dongwei Li, Qitong Huang, Lei Huang, Jikai Wen, Jing Luo, Qing Li, Yanling Peng, Yubo Zhang,

<h4>Background</h4>As a powerful tool, RNA-Seq has been widely used in various studies. Usually, unmapped RNA-seq reads have been considered as useless and been trashed or ignored.<h4>Results</h4>We develop a strategy to mining the full length sequence by unmapped reads combining with specific reverse transcription primers design and high throughput sequencing. In ... Read more >>

BMC Genomics (BMC genomics)
[2021, 22(1):857]

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Solidification of chromium-containing sludge with attapulgite combined alkali slag.

Huirong Lin, Linghao Zeng, Pengpeng Zhang, Binquan Jiao, YanChyuan Shiau, Dongwei Li,

To solve the harm caused by hazardous chromium-containing sludge (CCS, chromium-containing sludge) waste to humans and the environment, this study used attapulgite to strengthen alkali slag to prepare cementitious materials to solidify/stabilize CCS. Single-factor and orthogonal experiments were used to optimize the preparation parameters of alkali slag cementitious materials. The ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2021, :]

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Identification of New Transcription Factors that Can Promote Pluripotent Reprogramming.

Ping Huang, Jieying Zhu, Yu Liu, Guihuan Liu, Ran Zhang, Dongwei Li, Duanqing Pei, Ping Zhu,

<h4>Background</h4>Four transcription factors, Oct4, Sox2, Klf4, and c-Myc (the Yamanka factors), can reprogram somatic cells to induced pluripotent stem cells (iPSCs). Many studies have provided a number of alternative combinations to the non-Yamanaka factors. However, it is clear that many additional transcription factors that can generate iPSCs remain to be ... Read more >>

Stem Cell Rev Rep (Stem cell reviews and reports)
[2021, 17(6):2223-2234]

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SS18 regulates pluripotent-somatic transition through phase separation.

Junqi Kuang, Ziwei Zhai, Pengli Li, Ruona Shi, Wenjing Guo, Yuxiang Yao, Jing Guo, Guoqing Zhao, Jiangpin He, Shuyang Xu, Chuman Wu, Shengyong Yu, Chunhua Zhou, Linlin Wu, Yue Qin, Baomei Cai, Wei Li, Zichao Wu, Xiaoxi Li, Shilong Chu, Tingting Yang, Bo Wang, Shangtao Cao, Dongwei Li, Xiaofei Zhang, Jiekai Chen, Jing Liu, Duanqing Pei,

The transition from pluripotent to somatic states marks a critical event in mammalian development, but remains largely unresolved. Here we report the identification of SS18 as a regulator for pluripotent to somatic transition or PST by CRISPR-based whole genome screens. Mechanistically, SS18 forms microscopic condensates in nuclei through a C-terminal ... Read more >>

Nat Commun (Nature communications)
[2021, 12(1):4090]

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Publisher Correction: Genomic Analysis of the Insect-Killing Fungus Beauveria bassiana JEF-007 as a Biopesticide.

Se Jin Lee, Mi Rong Lee, Sihyeon Kim, Jong Cheol Kim, So Eun Park, Dongwei Li, Tae Young Shin, Yu-Shin Nai, Jae Su Kim,

Sci Rep (Scientific reports)
[2021, 11(1):14223]

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On full spark frames via Cauchy matrices

Dongwei Li,

Full spark frames have been widely applied in sparse signal processing, signal reconstruction with erasures and phase retrieval. Since testing whether a given frame is full spark is hard for NP under randomized polynomial-time reductions, hence the deterministic full spark (DFS) frames are particularly significant. However, the degree of freedom ... Read more >>

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Atypical Developmental Trajectories of Early Perception Among School-Age Children With Attention Deficit Hyperactivity Disorder During a Visual Search Task.

Xiangsheng Luo, Jialiang Guo, Dongwei Li, Lu Liu, Yanbo Chen, Yu Zhu, Stuart J Johnstone, Yufeng Wang, Yan Song, Li Sun,

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by cognitive deficits associated with attention. Prior studies have revealed the potential impact of ADHD on basic perception and cognitive ability in patients with ADHD. In this study, bilateral posterior P1 and N1 were measured in 122 Chinese children aged ... Read more >>

Child Dev (Child development)
[2021, 92(6):e1186-e1197]

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Induce Pluripotency via Specific distal enhancer-promoter associations

Xiusheng Zhu, Lei Huang, Dongwei Li, Jing Luo, Qitong Huang, Xueyan Wang, Yubo Zhang,

Induced pluripotent stem cell (iPSC) technology promises to be an inexhaustible source of any type of cell needed for therapeutic and research purposes. It is unclear that how distal enhancer-promoter associations/ 3D chromatin conformation involving in the capacity of self-renewal and pluripotency maintenance. In this study, we have selected a ... Read more >>

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Study on Solidification of Chromium-Containing Sludge With Alkali Slag Combined With Attapulgite

Huirong Lin, Linghao Zeng, Pengpeng Zhang, Bingquan Jiao, YanChyuan Shiau, Dongwei Li,

In order to solve the harm of hazardous waste chromium-containing sludge to humans and the environment, this paper uses attapulgite to strengthen alkali slag to prepare cementitious materials to solidify/stabilize chromium-containing sludge. Single-factor and orthogonal experiments were used to optimize the preparation parameters of alkali slag cementitious materials. The compressive ... Read more >>

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Super-Assembled Hierarchical CoO Nanosheets-Cu Foam Composites as Multi-Level Hosts for High-Performance Lithium Metal Anodes.

Runhao Zhang, Yong Li, Meng Wang, Dongwei Li, Junjie Zhou, Lei Xie, Tao Wang, Wei Tian, Yanjie Zhai, Hongyu Gong, Meng Gao, Kang Liang, Pu Chen, Biao Kong,

Achieving uniform lithium (Li) deposition is the key to tackle uncontrollable dendrite growth, which hinders the application of Li metal anodes. In this study, molten Li is thermally injected into a 3D framework by growing lithiophilic CoO nanosheets on Cu foam (CF). The CoO layer grown on the CF surface ... Read more >>

Small (Small (Weinheim an der Bergstrasse, Germany))
[2021, 17(23):e2101301]

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Chemical control of overwintering green algae to mitigate green tide in the Yellow Sea.

Ning Gong, Kuishuang Shao, Kun Shen, Yanbin Gu, Yu'an Liu, Jinqing Ye, Chuanming Hu, Lingyu Shen, Yanlong Chen, Dongwei Li, Jingfeng Fan,

It has been 14 years since the world's largest Ulva bloom appeared in the Yellow Sea, China in 2007. Although it is clear that the Ulva bloom originates from the culture system of Porphyra yezoensis (Nori) in the southern Yellow Sea, how to control it is still little understood. Since overwintering ... Read more >>

Mar Pollut Bull (Marine pollution bulletin)
[2021, 168:112424]

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Thermal cracking characteristics and mechanism of sandstone after high-temperature treatment

Weijing Xiao, Guo Yu, Haitao Li, Dongming Zhang, Shujian Li, Beichen Yu, Dongwei Li,

To study the thermal cracking characteristics and mechanism of sandstone after high-temperature treatment, the pore size distribution and micromorphology of sandstone were observed by nuclear magnetic resonance and scanning electron microscopy. Then, based on the Weibull distribution theory, a thermal elastic mechanical model of random heterogeneous rock was established for ... Read more >>

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Application of UV radiation for in-situ Cr(VI) reduction from contaminated soil with electrokinetic remediation.

Yi Zheng, Huilin Li, Qiu Yu, Lin Yu, Binquan Jiao, Dongwei Li,

Restoring hexavalent chromium (Cr(VI)) to trivalent chromium (Cr(III)) from contaminated soil is a cost-effective alternative for attenuating Cr(VI) toxicity to the ecosystem. A new electrokinetic remediation (EKR) system with UV light was explored to overcome an energy barrier to catalyze Cr(VI) reduction from the surface soil near the anodic reservoir. ... Read more >>

J Hazard Mater (Journal of hazardous materials)
[2021, 416:125806]

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Efficient induction of neural progenitor cells from human ESC/iPSCs on Type I Collagen.

Pengfei Liu, Shubin Chen, Yaofeng Wang, Xiaoming Chen, Yiping Guo, Chunhua Liu, Haitao Wang, Yifan Zhao, Di Wu, Yongli Shan, Jian Zhang, Chuman Wu, Dongwei Li, Yanmei Zhang, Tiancheng Zhou, Yaoyu Chen, Xiaobo Liu, Chenxu Li, Lihui Wang, Bei Jia, Jie Liu, Bo Feng, Jinglei Cai, Duanqing Pei,

A stable, rapid and effective neural differentiation method is essential for the clinical applications of human embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) in treating neurological disorders and diseases. Herein, we established a novel and robust monolayer differentiation method to produce functional neural progenitor cells (NPCs) from ... Read more >>

Sci China Life Sci (Science China. Life sciences)
[2021, :]

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Visual Working Memory Guides Spatial Attention: Evidence from alpha oscillations and sustained potentials.

Dongwei Li, Chenguang Zhao, Jialiang Guo, Yuanjun Kong, Hao Li, Boqi Du, Yulong Ding, Yan Song,

Selective attention can facilitate performance by filtering irrelevant information and temporary maintaining limited information to accomplish the current task. However, the neural substrate how attentional selection can be guided by visual working memory (vWM) is not clear. Here, we recorded electrophysiological signals during vWM retention and investigated the relationship between ... Read more >>

Neuropsychologia (Neuropsychologia)
[2021, 151:107719]

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Chromatin accessibility dynamics during cell fate reprogramming.

Dongwei Li, Xiaodong Shu, Ping Zhu, Duanqing Pei,

Genome architecture and chromatin dynamics govern the fate and identify of a cell. Recent advances in mapping chromatin landscapes offer valuable tools for the acquisition of accurate information regarding chromatin dynamics. Here we discuss recent findings linking chromatin dynamics to cell fate control. Specifically, chromatin undergoes a binary off/on switch ... Read more >>

EMBO Rep (EMBO reports)
[2021, 22(2):e51644]

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Beauveria bassiana ERL836 and JEF-007 with similar virulence show different gene expression when interacting with cuticles of western flower thrips, Frankniella occidentalis.

Sihyeon Kim, Jong Cheol Kim, Se Jin Lee, Mi Rong Lee, So Eun Park, Dongwei Li, Sehyeon Baek, Tae Young Shin, Jae Su Kim,

<h4>Background</h4>Insect-killing fungal species, Beauveria bassiana, is as an environment-friendly pest management tool, and many isolates are on the track of industrialization. However, some of B. bassiana isolates show similar morphology and virulence against insect pests, and so it is hard to differentiate them. Herein we used two patented isolates, ERL836 ... Read more >>

BMC Genomics (BMC genomics)
[2020, 21(1):836]

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Beauveria bassiana ERL836 and JEF-007 with similar virulence show different gene expression when interacting with cuticles of western flower thrips, Frankniella occidentalis

Sihyeon Kim, Jong Cheol Kim, Se Jin Lee, Mi rong Lee, So Eun Park, Dongwei Li, Sehyeon Baek, Tae Young Shin, Jae Su Kim,

<h4>Background: </h4> Insect-killing fungal species, Beauveria bassiana , is as an environment-friendly pest management tool, and many isolates are on the track of industrialization. However, some of B. bassiana isolates show similar morphology and virulence against insect pests, and so it is hard to differentiate them. Herein we used two ... Read more >>

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Soil Application of Metarhizium anisopliae JEF-314 Granules to Control, Flower Chafer Beetle, Protaetia brevitarsis seulensis.

Sihyeon Kim, Jong Cheol Kim, Se Jin Lee, Mi Rong Lee, So Eun Park, Dongwei Li, Sehyeon Baek, Tae Young Shin, Laila Gasmi, Jae Su Kim,

Root-feeding Scarabaeidae, particularly white grubs are considered among the most harmful coleopteran insect pests in turfgrass. In this work, sixteen entomopathogenic fungal species were assayed against flower chafer beetle, Protaetia brevitarsis (Coleoptera: Scarabaeidae) and Metarhizium anisopliae JEF-314 showed high virulence. The control ability of the isolate JEF-314 has been in ... Read more >>

Mycobiology (Mycobiology)
[2020, 48(2):139-147]

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Detoxification and immobilization of chromite ore processing residue using the alkali-activated cementitious materials mixed with ascorbic acid.

Ming Xia, Faheem Muhammad, Shujie Zhao, Lin Yu, Huirong Lin, Xiao Huang, Binquan Jiao, Yan Chyuan Shiau, Dongwei Li,

The existence of leachable Cr(Ⅵ) in chromite ore processing residue (COPR) makes it hazardous waste. Therefore, resourceful utilization of COPR is necessary to protect the ecosystem and living biota from hazardous effect of Cr(Ⅵ) caused by its leaching. In this study, detoxification and immobilization of COPR was carried out through ... Read more >>

J Environ Manage (Journal of environmental management)
[2020, 265:110350]

Cited: 2 times

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SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States.

Kaixin Wu, He Liu, Yaofeng Wang, Jiangping He, Shuyang Xu, Yaping Chen, Junqi Kuang, Jiadong Liu, Lin Guo, Dongwei Li, Ruona Shi, Li Shen, Yangming Wang, Xiaofei Zhang, Jie Wang, Duanqing Pei, Jiekai Chen,

Known as a histone H3K9 methyltransferase, SETDB1 is essential for embryonic development and pluripotent inner cell mass (ICM) establishment. However, its function in pluripotency regulation remains elusive. In this study, we find that under the "ground state" of pluripotency with two inhibitors (2i) of the MEK and GSK3 pathways, Setdb1-knockout ... Read more >>

Cell Rep (Cell reports)
[2020, 30(1):25-36.e6]

Cited: 15 times

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Synergism of citric acid and zero-valent iron on Cr(VI) removal from real contaminated soil by electrokinetic remediation.

Yi Zheng, Yujie Yan, Lin Yu, Huilin Li, Binquan Jiao, YanChyuan Shiau, Dongwei Li,

This study focused on enhanced electrokinetic remediation of Cr(VI) in real contaminated soil. The citric acid (CA) as the electrolyte and Fe(II) released from zero-valent iron (ZVI) under anoxic conditions functioned as the main reducer. They were used for overcoming the high insoluble Cr(VI) fraction in real contaminated soil and ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2020, 27(5):5572-5583]

Cited: 2 times

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Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency.

Nicholas Bredenkamp, Jian Yang, James Clarke, Giuliano Giuseppe Stirparo, Ferdinand von Meyenn, Sabine Dietmann, Duncan Baker, Rosalind Drummond, Yongming Ren, Dongwei Li, Chuman Wu, Maria Rostovskaya, Sarah Eminli-Meissner, Austin Smith, Ge Guo,

In contrast to conventional human pluripotent stem cells (hPSCs) that are related to post-implantation embryo stages, naive hPSCs exhibit features of pre-implantation epiblast. Naive hPSCs are established by resetting conventional hPSCs, or are derived from dissociated embryo inner cell masses. Here we investigate conditions for transgene-free reprogramming of human somatic ... Read more >>

Stem Cell Reports (Stem cell reports)
[2019, 13(6):1083-1098]

Cited: 13 times

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Correction: An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer.

Sunil Bhakta, Lisa M Crocker, Yvonne Chen, Meredith Hazen, Melissa M Schutten, Dongwei Li, Coenraad Kuijl, Rachana Ohri, Fiona Zhong, Kirsten A Poon, Mary Ann T Go, Eric Cheng, Robert Piskol, Ron Firestein, Aimee Fourie-O'Donohue, Katherine R Kozak, Helga Raab, Jo-Anne Hongo, Deepak Sampath, Mark S Dennis, Richard H Scheller, Paul Polakis, Jagath R Junutula,

Mol Cancer Ther (Molecular cancer therapeutics)
[2019, 18(11):2182]

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