Full Text Journal Articles by
Author Dongjun Cheng


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Combination of the Archimedes Navigation System and cryobiopsy in diagnosis of diffuse lung disease.

Quncheng Zhang, Huili Li, Yunxia An, Dongjun Cheng, Guannan Sun, Yong Qi, Weixia Xuan, Zheng Wang, Xiaoju Zhang,

<h4>Objective</h4>To evaluate the efficacy of the Archimedes Navigation System (Broncus Medical, San Jose, CA, USA) for guidance during transbronchial cryobiopsy and the incidence of complications in patients with diffuse lung disease.<h4>Methods</h4>High-resolution computed tomography and transbronchial cryobiopsy were used to evaluate eight patients with diffuse lung disease. The Archimedes Navigation System ... Read more >>

J Int Med Res (The Journal of international medical research)
[2021, 49(7):3000605211016665]

Cited: 0 times

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Long non-coding RNA-HAGLR suppressed tumor growth of lung adenocarcinoma through epigenetically silencing E2F1.

Xiaobin Guo, Zhuochang Chen, Limin Zhao, Dongjun Cheng, Wei Song, Xiaoju Zhang,

Emerging evidence indicates that long noncoding RNAs (LncRNAs) are new players in gene regulation but their mechanisms of action are mainly undocumented. In this study, we investigated LncRNA alterations that contribute to lung cancer by analyzing published microarray data in Gene Expression Obminus (GEO) and The Cancer Genome Atlas RNA ... Read more >>

Exp Cell Res (Experimental cell research)
[2019, 382(1):111461]

Cited: 8 times

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The effects of transient receptor potential channel (TRPC) on airway smooth muscle cell isolated from asthma model mice.

Xiaoyu Zhang, Zhixin Zhao, Lijun Ma, Yali Guo, Xiaosu Li, Limin Zhao, Cuijie Tian, Xueyi Tang, Dongjun Cheng, Zhuochang Chen, Luoxian Zhang,

This study aimed to validate whether transient receptor potential channel1 (TRPC1) and TRPC3 participate in the regulation the proliferation of airway smooth muscle cells (ASMCs) through modulating calcium ion (Ca<sup>2+</sup> ) influx in vitro. Chronic model of murine asthma was induced and ASMCs isolated from asthmatic mice were used in ... Read more >>

J Cell Biochem (Journal of cellular biochemistry)
[2018, 119(7):6033-6044]

Cited: 6 times

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AKIP1 promoted epithelial-mesenchymal transition of non-small-cell lung cancer via transactivating ZEB1.

Xiaobin Guo, Limin Zhao, Dongjun Cheng, Qing Mu, Hongyan Kuang, Keqing Feng,

Non-small-cell lung cancer (NSCLC) is one of the leading death-related malignancies worldwide with elusive molecular mechanisms. A-kinase interacting protein 1 (AKIP1) is an important regulator controlling metastasis, lymphangiogenesis and angiogenesis. However, the role of AKIP1 in NSCLC progression is still little known. Here, we found that AKIP1 was overexpressed in ... Read more >>

Am J Cancer Res (American journal of cancer research)
[2017, 7(11):2234-2244]

Cited: 14 times

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Tumor-associated calcium signal transducer 2 regulates neovascularization of non-small-cell lung cancer via activating ERK1/2 signaling pathway.

Xiaobin Guo, Xiaoming Zhu, Limin Zhao, Xiao Li, Dongjun Cheng, Keqing Feng,

Lung cancer, especially the non-small-cell lung cancer, is a highly aggressive vascular cancer with excessively activated signaling pathways. Tumor-associated calcium signal transducer 2, also known as trop2, was identified to be correlated with tumor proliferation and invasion of non-small-cell lung cancer; however, the biological role of trop2 in neovascularization of ... Read more >>

Tumour Biol (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine)
[2017, 39(3):1010428317694324]

Cited: 2 times

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Clinical significance of DAPK promoter hypermethylation in lung cancer: a meta-analysis.

Ying Li, Min Zhu, Xiaoju Zhang, Dongjun Cheng, Xitao Ma,

Death-associated protein kinase 1 (DAPK) is an important serine/threonine kinase involved in various cellular processes, including apoptosis, autophagy, and inflammation. DAPK expression and activity are deregulated in a variety of diseases including cancer. Methylation of the DAPK gene is common in many types of cancer and can lead to loss ... Read more >>

Drug Des Devel Ther (Drug design, development and therapy)
[2015, 9:1785-1796]

Cited: 4 times

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The effects of protein kinase C (PKC) on the tension of normal and passively sensitized human airway smooth muscle and the activity of voltage-dependent delayed rectifier potassium channel (Kv).

Dongjun Cheng, Yongjian Xu, Xiansheng Liu, Limin Zhao, Shengdao Xiong, Zhenxiang Zhang,

The effects of protein kinase C (PKC) on the tension and the activity of voltage-dependent delayed rectifier potassium channel (K(y)) were examined in normal and passively sensitized human airway smooth muscle (HASM), by measuring tones and whole-cell patch clamp techniques, and the K(v) activities and membrane potential (E (m)) were ... Read more >>

J Huazhong Univ Sci Technolog Med Sci (Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban)
[2007, 27(2):153-156]

Cited: 1 time

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