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Author Dominic Wilkinson

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Evaluation of a hypothetical decision-support tool for intensive care triage of patients with coronavirus disease 2019 (COVID-19)

Emily Simon Thomas, Bryony Peiris, Leon Di Stefano, Matthew Rowland, Dominic Wilkinson,

<ns3:p> <h4>Background: </h4> At the start of the coronavirus disease 2019 (COVID-19) pandemic there was widespread concern about potentially overwhelming demand for intensive care and the need for intensive care unit (ICU) triage. In March 2020, a draft United Kingdom (UK) guideline proposed a decision-support tool (DST). We sought to ... Read more >>

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Should we delay covid-19 vaccination in children?

Dominic Wilkinson, Ilora Finlay, Andrew J Pollard, Lisa Forsberg, Anthony Skelton,

BMJ (BMJ (Clinical research ed.))
[2021, 374:n1687]

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Surrogate uncertainty: who decides?

Dominic Wilkinson,

J Med Ethics (Journal of medical ethics)
[2021, :]

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The Forget-Me-Not dHCP study: 7 Tesla high resolution diffusion imaging in the unfixed post-mortem neonatal brain

Wenchuan Wu, Luke Baxter, Sebastian Rieger, Eleri Adams, Jesper LR Andersson, Maria Cobo Andrade, Foteini Andritsou, Matteo Bastiani, Ria Evans Fry, Robert Frost, Sean Fitzgibbon, Sean Foxley, Darren Fowler, Chris Gallagher, Amy FD Howard, Joseph Hajnal, Fiona Moultrie, Vaneesha Monk, David Andrew Porter, Daniel Papp, Anthony Price, Jerome Sallet, Michael Sanders, Dominic Wilkinson, Stephen Smith, Rebeccah Slater, Karla Miller,

Diffusion MRI of the neonatal brain allows investigation of the organisational structure of maturing fibres during brain development. Post-mortem imaging has the potential to achieve high resolution by using long scan times, enabling precise assessment of small structures. The Forget-Me-Not study, part of the Developing Human Connectome Project (dHCP), aims ... Read more >>

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[Newborn resuscitation and support of transition of infants at birth].

John Madar, Charles C Roehr, Sean Ainsworth, Hege Ersda, Colin Morley, Mario Rüdiger, Christiane Skåre, Tomasz Szczapa, Arjan Te Pas, Daniele Trevisanuto, Berndt Urlesberger, Dominic Wilkinson, Jonathan P Wyllie,

The European Resuscitation Council has produced these newborn life support guidelines, which are based on the International Liaison Committee on Resuscitation (ILCOR) 2020 Consensus on Science and Treatment Recommendations (CoSTR) for Neonatal Life Support. The guidelines cover the management of the term and preterm infant. The topics covered include an ... Read more >>

Notf Rett Med (Notfall & rettungsmedizin)
[2021, :1-47]

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Ethical factors determining ECMO allocation during the COVID-19 pandemic.

Bernadine Dao, Julian Savulescu, Jacky Y Suen, John F Fraser, Dominic J C Wilkinson,

<h4>Background</h4>ECMO is a particularly scarce resource during the COVID-19 pandemic. Its allocation involves ethical considerations that may be different to usual times. There is limited pre-pandemic literature on the ethical factors that ECMO physicians consider during ECMO allocation. During the pandemic, there has been relatively little professional guidance specifically relating ... Read more >>

BMC Med Ethics (BMC medical ethics)
[2021, 22(1):70]

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Reply letter to: Intubation in neonatal resuscitation - Compelling necessity or incalculable risk?

Charles C Roehr, John Madar, Colin J Morley, Sean Ainsworth, Hege Ersdal, Mario Rüdiger, Christiane Skåre, Tomasz Szczapa, Arjan Te Pas, Daniele Trevisanuto, Berndt Urlesberger, Dominic Wilkinson, Jonathan P Wyllie,

Resuscitation (Resuscitation)
[2021, :]

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Ethical heuristics for pandemic allocation of ventilators across hospitals.

César Palacios-González, Jonathan Pugh, Dominic Wilkinson, Julian Savulescu,

In response to the COVID-19 pandemic philosophers and governments have proposed scarce resource allocation guidelines. Their purpose is to advise healthcare professionals on how to ethically allocate scarce medical resources. One challenging feature of the pandemic has been the large numbers of patients needing mechanical ventilatory support. Guidelines have paradigmatically ... Read more >>

Dev World Bioeth (Developing world bioethics)
[2021, :]

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Viability and thresholds for treatment of extremely preterm infants: survey of UK neonatal professionals.

Lydia Mietta Di Stefano, Katherine Wood, Helen Mactier, Sarah Elizabeth Bates, Dominic Wilkinson,

<h4>Background</h4>Decisions about treatments for extremely preterm infants (EPIs) born in the 'grey zone' of viability can be ethically complex. This 2020 survey aimed to determine views of UK neonatal staff about thresholds for treatment of EPIs given a recently revised national Framework for Practice from the British Association of Perinatal ... Read more >>

Arch Dis Child Fetal Neonatal Ed (Archives of disease in childhood. Fetal and neonatal edition)
[2021, :]

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Ethics and evidence: learning lessons from pandemic triage.

Dominic J C Wilkinson,

Lancet Respir Med (The Lancet. Respiratory medicine)
[2021, 9(4):328-330]

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British laypeople's attitudes towards gradual sedation, sedation to unconsciousness and euthanasia at the end of life.

Antony Takla, Julian Savulescu, Andreas Kappes, Dominic J C Wilkinson,

<h4>Background</h4>Many patients at the end of life require analgesia to relieve pain. Additionally, up to 1/5 of patients in the UK receive sedation for refractory symptoms at the end of life. The use of sedation in end-of-life care (EOLC) remains controversial. While gradual sedation to alleviate intractable suffering is generally ... Read more >>

PLoS One (PloS one)
[2021, 16(3):e0247193]

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European Resuscitation Council Guidelines 2021: Newborn resuscitation and support of transition of infants at birth.

John Madar, Charles C Roehr, Sean Ainsworth, Hege Ersdal, Colin Morley, Mario Rüdiger, Christiane Skåre, Tomasz Szczapa, Arjan Te Pas, Daniele Trevisanuto, Berndt Urlesberger, Dominic Wilkinson, Jonathan P Wyllie,

The European Resuscitation Council has produced these newborn life support guidelines, which are based on the International Liaison Committee on Resuscitation (ILCOR) 2020 Consensus on Science and Treatment Recommendations (CoSTR) for Neonatal Life Support. The guidelines cover the management of the term and preterm infant. The topics covered include an ... Read more >>

Resuscitation (Resuscitation)
[2021, 161:291-326]

Cited: 4 times

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Sense and sensitivity: can an inaccurate test be better than no test at all?

Jonathan Pugh, Dominic Wilkinson, Julian Savulescu,

The UK government has put lateral flow antigen tests (LFATs) at the forefront of its strategy to scale-up testing in the coronavirus pandemic. However, evidence from a pilot trial using an LFAT to identify asymptomatic infections in the community suggested that the test missed over half of the positive cases ... Read more >>

J Med Ethics (Journal of medical ethics)
[2021, :]

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Dissonance and consonance about death.

Dominic Wilkinson,

J Med Ethics (Journal of medical ethics)
[2021, :]

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Surrogate decision making in crisis.

Dominic Wilkinson, Thillagavathie Pillay,

Care of the critically ill newborn includes support for the birth mother/parents with regular updates around the clinical condition of the baby, and involvement in discussions around complex decision-making issues . Discussions around continuation or discontinuation of life-sustaining are challenging even in the most straightforward of cases, but what happens ... Read more >>

J Med Ethics (Journal of medical ethics)
[2021, :]

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Queue questions: Ethics of COVID-19 vaccine prioritization.

Alberto Giubilini, Julian Savulescu, Dominic Wilkinson,

The rapid development of vaccines against COVID-19 represents a huge achievement, and offers hope of ending the global pandemic. At least three COVID-19 vaccines have been approved or are about to be approved for distribution in many countries. However, with very limited initial availability, only a minority of the population ... Read more >>

Bioethics (Bioethics)
[2021, 35(4):348-355]

Cited: 2 times

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Beyond Individual Triage: Regional Allocation of Life-Saving Resources such as Ventilators in Public Health Emergencies.

Jonathan Pugh, Dominic Wilkinson, Cesar Palacios-Gonzalez, Julian Savulescu,

In the first wave of the COVID-19 pandemic, healthcare workers in some countries were forced to make distressing triaging decisions about which individual patients should receive potentially life-saving treatment. Much of the ethical discussion prompted by the pandemic has concerned which moral principles should ground our response to these individual ... Read more >>

Health Care Anal (Health care analysis : HCA : journal of health philosophy and policy)
[2021, :]

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Frailty Triage: Is Rationing Intensive Medical Treatment on the Grounds of Frailty Ethical?

Dominic J C Wilkinson,

In early 2020, a number of countries developed and published intensive care triage guidelines for the pandemic. Several of those guidelines, especially in the UK, encouraged the explicit assessment of clinical frailty as part of triage. Frailty is relevant to resource allocation in at least three separate ways, through its ... Read more >>

Am J Bioeth (The American journal of bioethics : AJOB)
[2020, :1-22]

Cited: 1 time

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Which factors should be included in triage? An online survey of the attitudes of the UK general public to pandemic triage dilemmas.

Dominic Wilkinson, Hazem Zohny, Andreas Kappes, Walter Sinnott-Armstrong, Julian Savulescu,

<h4>Objective</h4>As cases of COVID-19 infections surge, concerns have renewed about intensive care units (ICUs) being overwhelmed and the need for specific triage protocols over winter. This study aimed to help inform triage guidance by exploring the views of lay people about factors to include in triage decisions.<h4>Design, setting and participants</h4>Online ... Read more >>

BMJ Open (BMJ open)
[2020, 10(12):e045593]

Cited: 5 times

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A public health ethic should inform policies on COVID-19 immunity passports - Authors' reply.

Rebecca C H Brown, Julian Savulescu, Dominic Kelly, Dominic Wilkinson,

Lancet Infect Dis (The Lancet. Infectious diseases)
[2021, 21(4):456-457]

Cited: 1 time

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A conscious choice: Is it ethical to aim for unconsciousness at the end of life?

Antony Takla, Julian Savulescu, Dominic J C Wilkinson,

One of the most commonly referenced ethical principles when it comes to the management of dying patients is the doctrine of double effect (DDE). The DDE affirms that it is acceptable to cause side effects (e.g. respiratory depression) as a consequence of symptom-focused treatment. Much discussion of the ethics of ... Read more >>

Bioethics (Bioethics)
[2021, 35(3):284-291]

Cited: 2 times

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Sleep softly: Schubert, ethics and the value of dying well.

Dominic Wilkinson,

Ethical discussions about medical treatment for seriously ill babies or children often focus on the 'value of life' or on 'quality of life' and what that might mean. In this paper, I look at the other side of the coin-on the value of death, and on the quality of dying. ... Read more >>

J Med Ethics (Journal of medical ethics)
[2020, :]

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Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission.

Christopher Eccleston, Emma Fisher, Richard F Howard, Rebeccah Slater, Paula Forgeron, Tonya M Palermo, Kathryn A Birnie, Brian J Anderson, Christine T Chambers, Geert Crombez, Gustaf Ljungman, Isabel Jordan, Zachary Jordan, Caitriona Roberts, Neil Schechter, Christine B Sieberg, Dick Tibboel, Suellen M Walker, Dominic Wilkinson, Chantal Wood,

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2021, 5(1):47-87]

Cited: 6 times

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The scientific and ethical feasibility of immunity passports.

Rebecca C H Brown, Dominic Kelly, Dominic Wilkinson, Julian Savulescu,

There is much debate about the use of immunity passports in the response to the COVID-19 pandemic. Some have argued that immunity passports are unethical and impractical, pointing to uncertainties relating to COVID-19 immunity, issues with testing, perverse incentives, doubtful economic benefits, privacy concerns, and the risk of discriminatory effects. ... Read more >>

Lancet Infect Dis (The Lancet. Infectious diseases)
[2021, 21(3):e58-e63]

Cited: 11 times

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Are Generational Welfare Trades Always Unjust?

Walter Veit, Julian Savulescu, David Hunter, Brian D Earp, Dominic Wilkinson,

Am J Bioeth (The American journal of bioethics : AJOB)
[2020, 20(9):70-72]

Cited: 1 time

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