Full Text Journal Articles by
Author Dolores Hill

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SEROPREVALENCE OF TOXOPLASMA GONDII IN MARKET HOGS COLLECTED FROM U.S. SLAUGHTERHOUSES.

Jorrell Fredericks, Dolores E Hill, Diane S Hawkins-Cooper, Valsin M Fournet, Jonathan Calero-Landa, Brandon Adams, Alexis Johnson, Marwa Barrow, Jovan Aquino, Talatha Mahmoud, Victoria Murphy, Alec Barlow, Priyal Patel, Megan George, Nadya Chehab, Matthew Kramer, Nate E Bauer,

Foodborne pathogens continue to pose a public health risk and can cause serious illness and outbreaks of disease in consumers. The consumption of raw or undercooked infected meat, such as pork containing infectious stages of Toxoplasma gondii, may be a major route of transmission to humans. Given the occasional presence ... Read more >>

J Parasitol (The Journal of parasitology)
[2021, 107(3):404-410]

Cited: 0 times

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Toxoplasmosis Outbreak Associated With Toxoplasma gondii-Contaminated Venison-High Attack Rate, Unusual Clinical Presentation, and Atypical Genotype.

Amy C Schumacher, Lina I Elbadawi, Traci DeSalvo, Anne Straily, Daniel Ajzenberg, David Letzer, Ellen Moldenhauer, Tammy L Handly, Dolores Hill, Marie-Laure Dardé, Christelle Pomares, Karine Passebosc-Faure, Kristine Bisgard, Carlos A Gomez, Cindy Press, Stephanie Smiley, José G Montoya, James J Kazmierczak,

<h4>Background</h4>During 2017, in response to a physician's report, the Wisconsin Department of Health Services, Division of Public Health, began investigating an outbreak of febrile illness among attendees of a retreat where never frozen, intentionally undercooked, locally harvested venison was served. Preliminary testing tentatively identified the illness as toxoplasmosis.<h4>Methods</h4>Confirmatory human serology ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2021, 72(9):1557-1565]

Cited: 4 times

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Molecular and metabolomic changes in the proximal colon of pigs infected with Trichuris suis.

Harry D Dawson, Celine Chen, Robert W Li, Lauren Nicole Bell, Terez Shea-Donohue, Helene Kringel, Ethiopia Beshah, Dolores E Hill, Joseph F Urban,

The pig whipworm Trichuris suis is important in swine production because of its negative effects on pig performance and, notably, to some humans with inflammatory bowel disease as a therapeutic agent that modulates inflammation. The proximal colon of T. suis-infected pigs exhibited general inflammation around day 21 after inoculation with ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):12853]

Cited: 2 times

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All about Toxoplasma gondii infections in pigs: 2009-2020.

Jitender P Dubey, Camila K Cerqueira-Cézar, Fernando H A Murata, Oliver C H Kwok, Dolores Hill, Yurong Yang, Chunlei Su,

Toxoplasma gondii infections are common in humans and animals worldwide. Toxoplasma gondii infection in pigs continues to be of public health concern. Pigs are important for the economy of many countries, particularly, USA, China, and European countries. Among the many food animals, pigs are considered the most important for T. ... Read more >>

Vet Parasitol (Veterinary parasitology)
[2020, 288:109185]

Cited: 5 times

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Inactivation of Toxoplasma gondii Bradyzoites after Salt Exposure during Preparation of Dry-Cured Hams.

Jorrell Fredericks, Diane S Hawkins-Cooper, Dolores E Hill, John B Luchansky, Anna C S Porto-Fett, Brad A Shoyer, Valsin M Fournet, Joseph F Urban, Jitender P Dubey,

<h4>Abstract</h4>Foodborne pathogens continue to pose a public health risk and can cause serious illness and significant outbreaks of disease in consumers. Toxoplasmosis is a zoonotic disease that occurs worldwide and is caused by the protozoan parasite, Toxoplasma gondii. The consumption of raw or undercooked infected meat, including pork, that contains ... Read more >>

J Food Prot (Journal of food protection)
[2020, 83(6):1038-1042]

Cited: 0 times

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Hepatitis E Virus in Pigs from Slaughterhouses, United States, 2017-2019.

Harini Sooryanarain, Connie L Heffron, Dolores E Hill, Jorrell Fredericks, Benjamin M Rosenthal, Stephen R Werre, Tanja Opriessnig, Xiang-Jin Meng,

Hepatitis E virus (HEV) RNA was detected in 6.3% and HEV IgG in 40% of 5,033 serum samples from market-weight pigs at 25 slaughterhouses in 10 US states. The prevalent HEV genotype was zoonotic genotype 3, group 2. Blood of HEV-viremic pigs from slaughterhouses may contaminate pork supply chains. ... Read more >>

Emerg Infect Dis (Emerging infectious diseases)
[2020, 26(2):354-357]

Cited: 7 times

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Toxoplasma gondii Serointensity and Seropositivity: Heritability and Household-Related Associations in the Old Order Amish.

Allyson R Duffy, Jeffrey R O'Connell, Mary Pavlovich, Kathleen A Ryan, Christopher A Lowry, Melanie Daue, Uttam K Raheja, Lisa A Brenner, André O Markon, Cecile M Punzalan, Aline Dagdag, Dolores E Hill, Toni I Pollin, Andreas Seyfang, Maureen W Groer, Braxton D Mitchell, Teodor T Postolache,

<i>Toxoplasma gondii</i> (<i>T. gondii</i>) is an intracellular parasite infecting one third of the world's population. Latent <i>T. gondii</i> infection has been associated with mental illness, including schizophrenia and suicidal behavior. <i>T. gondii</i> IgG antibody titers were measured via ELISA. The heritability of <i>T. gondii</i> IgG was estimated using a mixed ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2019, 16(19):]

Cited: 3 times

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Correction to: The One Health Approach to Toxoplasmosis: Epidemiology, Control, and Prevention Strategies.

A Alonso Aguirre, Travis Longcore, Michelle Barbieri, Haydee Dabritz, Dolores Hill, Patrice N Klein, Christopher Lepczyk, Emily L Lilly, Rima McLeod, Judith Milcarsky, Caroline E Murphy, Chunlei Su, Elizabeth VanWormer, Robert Yolken, Grant C Sizemore,

This article was originally published electronically on the publisher's internet portal (currently SpringerLink) on April 3, 2019 without open access. ... Read more >>

Ecohealth (EcoHealth)
[2019, 16(2):391]

Cited: 0 times

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International Commission on Trichinellosis: Recommendations on pre-harvest control of Trichinella in food animals.

H Ray Gamble, Lis Alban, Dolores Hill, Dave Pyburn, Brad Scandrett,

Transmission of Trichinella to domestic livestock, notably pigs, is limited to certain risk factors including feeding of raw meat-containing waste products or animal carcasses and exposure to infected rodents and wildlife. Prevention of infection in food animals is dependent on eliminating risk of exposure to these potential sources of Trichinella. ... Read more >>

Food Waterborne Parasitol (Food and waterborne parasitology)
[2019, 15:e00039]

Cited: 1 time

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EXPOSURE OF ALASKA BROWN BEARS (URSUS ARCTOS) TO BACTERIAL, VIRAL, AND PARASITIC AGENTS VARIES SPATIOTEMPORALLY AND MAY BE INFLUENCED BY AGE.

Andrew M Ramey, Christopher A Cleveland, Grant V Hilderbrand, Kyle Joly, David D Gustine, Buck Mangipane, William B Leacock, Anthony P Crupi, Dolores E Hill, Jitender P Dubey, Michael J Yabsley,

We collected blood and serum from 155 brown bears (Ursus arctos) inhabiting five locations in Alaska, US during 2013-16 and tested samples for evidence of prior exposure to a suite of bacterial, viral, and parasitic agents. Antibody seroprevalence among Alaska brown bears was estimated to be 15% for Brucella spp., ... Read more >>

J Wildl Dis (Journal of wildlife diseases)
[2019, 55(3):576-588]

Cited: 2 times

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International Commission on Trichinellosis: Recommendations on post-harvest control of Trichinella in food animals.

Karsten Noeckler, Edoardo Pozio, Joke van der Giessen, Dolores E Hill, H Ray Gamble,

Domestic and wild animals which consume meat are at risk of becoming infected with Trichinella and therefore may pose a public health risk. Among domestic livestock, pigs are most commonly associated with Trichinella infection, but human outbreaks have also resulted from consumption of horsemeat, wild boar, bear, walrus and other ... Read more >>

Food Waterborne Parasitol (Food and waterborne parasitology)
[2019, 14:e00041]

Cited: 3 times

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International Commission on Trichinellosis: Recommendations on the use of serological tests for the detection of Trichinella infection in animals and humans.

Fabrizio Bruschi, Maria Angeles Gómez-Morales, Dolores E Hill,

Serological methods are widely used for detection of infections in animals and humans. The recommendations provided here take into account the best current methods for the serological detection of Trichinella infection. They are based on current scientific information including unpublished data from laboratories with relevant expertise in this field. These ... Read more >>

Food Waterborne Parasitol (Food and waterborne parasitology)
[2019, 14:e00032]

Cited: 8 times

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Comparative genomics of the major parasitic worms.

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Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating chronic infections of humans and animals, decimate crop production and are a major impediment to socioeconomic development. Here we report a broad comparative study of 81 genomes of parasitic and non-parasitic worms. We have identified gene family births and hundreds of expanded ... Read more >>

Nat Genet (Nature genetics)
[2019, 51(1):163-174]

Cited: 93 times

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No evidence for airborne transmission of Toxoplasma gondii in a very high prevalence area in Lancaster County.

Abhishek Wadhawan, Dolores E Hill, Aline Dagdag, Hira Mohyuddin, Patrick Donnelly, Jeffrey L Jones, Teodor T Postolache,

Background:Toxoplasma gondii (T. gondii) has been associated with acute food-borne illness, chronic low-grade inflammation, neuropsychiatric conditions and reactivation of chronic latent infection in immunocompetent hosts. Primary infection with T. gondii in pregnant women can lead to congenital toxoplasmosis. In addition to well-known oral tissue-cyst or oocyst ingestion, we hypothesized that ... Read more >>

Pteridines (Pteridines)
[2018, 29(1):172-178]

Cited: 0 times

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Survey for selected pathogens in wild pigs (Sus scrofa) from Guam, Marianna Islands, USA.

Christopher A Cleveland, Anthony DeNicola, J P Dubey, Dolores E Hill, Roy D Berghaus, Michael J Yabsley,

Pigs (Sus scrofa) were introduced to Guam in the 1600's and are now present in high densities throughout the island. Wild pigs are reservoirs for pathogens of concern to domestic animals and humans. Exposure to porcine parvovirus, transmissible gastroenteritis, and Leptospira interrogans has been documented in domestic swine but data ... Read more >>

Vet Microbiol (Veterinary microbiology)
[2017, 205:22-25]

Cited: 8 times

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The prevalence and genotypic analysis of Toxoplasma gondii from individuals in Scotland, 2006-2012.

Alison Burrells, Marieke Opsteegh, Kevin G Pollock, Claire L Alexander, Jean Chatterton, Roger Evans, Robert Walker, Chris-Anne McKenzie, Dolores Hill, Elisabeth A Innes, Frank Katzer,

<h4>Background</h4>Contemporary information relating to the prevalence of Toxoplasma gondii in humans is lacking for the UK population, with even less information available about the human prevalence of the parasite in Scotland. To address this, two different study groups were used to determine the prevalence and genotypes of Toxoplasma gondii in ... Read more >>

Parasit Vectors (Parasites & vectors)
[2016, 9(1):324]

Cited: 8 times

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Seroepidemiologic study on the prevalence of Toxoplasma gondii and Trichinella spp. infections in black bears (Ursus americanus) in Pennsylvania, USA.

Jitender P Dubey, Justin Brown, Mark Ternent, Shiv K Verma, Dolores E Hill, Camila K Cerqueira-Cézar, Oliver C H Kwok, Rafael Calero-Bernal, Jan G Humphreys,

The protozoan Toxoplasma gondii and the metazoan Trichinella spp. infect virtually all warm-blooded animals, including birds, humans, livestock, and marine mammals. Both parasitic infections can cause serious illness in human beings and can be acquired by ingesting under-cooked meat harboring infective stages. Approximately 3500 black bears (Ursus americanus) are legally-harvested ... Read more >>

Vet Parasitol (Veterinary parasitology)
[2016, 229:76-80]

Cited: 1 time

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Toxoplasma gondii as a Parasite in Food: Analysis and Control.

Dolores E Hill, Jitender P Dubey,

Foodborne infections are a significant cause of morbidity and mortality worldwide, and foodborne parasitic diseases, though not as widespread as bacterial and viral infections, are common on all continents and in most ecosystems, including arctic, temperate, and tropical regions. Outbreaks of disease resulting from foodstuffs contaminated by parasitic protozoa have ... Read more >>

Microbiol Spectr (Microbiology spectrum)
[2016, 4(4):]

Cited: 13 times

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Quantifying the Risk of Human Toxoplasma gondii Infection Due to Consumption of Domestically Produced Lamb in the United States.

Miao Guo, Abhinav Mishra, Robert L Buchanan, Jitender P Dubey, Dolores E Hill, H Ray Gamble, Abani K Pradhan,

<h4>Unlabelled</h4>Toxoplasma gondii is a prevalent protozoan parasite worldwide. Human toxoplasmosis is responsible for considerable morbidity and mortality in the United States, and meat products have been identified as an important source of T. gondii infections in humans. The goal of this study was to develop a farm-to-table quantitative microbial risk ... Read more >>

J Food Prot (Journal of food protection)
[2016, 79(7):1181-1187]

Cited: 3 times

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Antibody Detection and Molecular Characterization of Toxoplasma gondii from Bobcats (Lynx rufus), Domestic Cats (Felis catus), and Wildlife from Minnesota, USA.

Shiv K Verma, Larissa Minicucci, Darby Murphy, Michelle Carstensen, Carolin Humpal, Paul Wolf, Rafael Calero-Bernal, Camila K Cerqueira-Cézar, Oliver C H Kwok, Chunlei Su, Dolores Hill, Jitender P Dubey,

Little is known of the epidemiology of toxoplasmosis in Minnesota. Here, we evaluated Toxoplasma gondii infection in 50 wild bobcats (Lynx rufus) and 75 other animals on/near 10 cattle farms. Antibodies to T. gondii were assayed in serum samples or tissue fluids by the modified agglutination test (MAT, cut-off 1:25). Twenty ... Read more >>

J Eukaryot Microbiol (The Journal of eukaryotic microbiology)
[2016, 63(5):567-571]

Cited: 3 times

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A Systematic Meta-Analysis of Toxoplasma gondii Prevalence in Food Animals in the United States.

Miao Guo, Abhinav Mishra, Robert L Buchanan, Jitender P Dubey, Dolores E Hill, H Ray Gamble, Jeffrey L Jones, Abani K Pradhan,

Toxoplasma gondii is a widely distributed protozoan parasite. The Centers for Disease Control and Prevention reported that T. gondii is one of three pathogens (along with Salmonella and Listeria), that together account for >70% of all deaths due to foodborne illness in the United States. Food animals are reservoirs for ... Read more >>

Foodborne Pathog Dis (Foodborne pathogens and disease)
[2016, 13(3):109-118]

Cited: 15 times

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Toxoplasmosis in geese and detection of two new atypical Toxoplasma gondii strains from naturally infected Canada geese (Branta canadensis).

Shiv Kumar Verma, Rafael Calero-Bernal, Camila K Cerqueira-Cézar, Oliver C H Kwok, Mike Dudley, Tiantian Jiang, Chunlei Su, Dolores Hill, Jitender P Dubey,

Wild birds are important in the epidemiology of toxoplasmosis because they can serve as reservoir hosts, and vectors of zoonotic pathogens including Toxoplasma gondii. Canada goose (Branta canadensis) is the most widespread geese in North America. Little is known concerning T. gondii infection in both migratory, and local resident populations ... Read more >>

Parasitol Res (Parasitology research)
[2016, 115(5):1767-1772]

Cited: 6 times

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Waterborne toxoplasmosis investigated and analysed under hydrogeological assessment: new data and perspectives for further research.

Flávia Pereira Vieira, Maria da Glória Alves, Livia Mattos Martins, Alba Lucínia Peixoto Rangel, Jitender Prakash Dubey, Dolores Hill, Lilian Maria Garcia Bahia-Oliveira,

We present a set of data on human and chicken Toxoplasma gondii seroprevalence that was investigated and analysed in light of groundwater vulnerability information in an area endemic for waterborne toxoplasmosis in Brazil. Hydrogeological assessment was undertaken to select sites for water collection from wells for T. gondii oocyst testing ... Read more >>

Mem Inst Oswaldo Cruz (Memorias do Instituto Oswaldo Cruz)
[2015, 110(7):929-935]

Cited: 8 times

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Development of Dose-Response Models to Predict the Relationship for Human Toxoplasma gondii Infection Associated with Meat Consumption.

Miao Guo, Abhinav Mishra, Robert L Buchanan, Jitender P Dubey, Dolores E Hill, H Ray Gamble, Jeffrey L Jones, Xianzhi Du, Abani K Pradhan,

Toxoplasma gondii is a protozoan parasite that is responsible for approximately 24% of deaths attributed to foodborne pathogens in the United States. It is thought that a substantial portion of human T. gondii infections is acquired through the consumption of meats. The dose-response relationship for human exposures to T. gondii-infected ... Read more >>

Risk Anal (Risk analysis : an official publication of the Society for Risk Analysis)
[2016, 36(5):926-938]

Cited: 4 times

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Qualitative Assessment for Toxoplasma gondii Exposure Risk Associated with Meat Products in the United States.

Miao Guo, Robert L Buchanan, Jitender P Dubey, Dolores E Hill, Elisabetta Lambertini, Yuqing Ying, H Ray Gamble, Jeffrey L Jones, Abani K Pradhan,

Toxoplasma gondii is a global protozoan parasite capable of infecting most warm-blooded animals. Although healthy adult humans generally have no symptoms, severe illness does occur in certain groups, including congenitally infected fetuses and newborns, immunocompromised individuals including transplant patients. Epidemiological studies have demonstrated that consumption of raw or undercooked meat ... Read more >>

J Food Prot (Journal of food protection)
[2015, 78(12):2207-2219]

Cited: 10 times

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