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Author Dianne Miller

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Declining rates of cervical intraepithelial neoplasia in British Columbia, Canada: An ecological analysis on the effects of the school-based human papillomavirus vaccination program.

Robine Donken, Dirk van Niekerk, Jeremy Hamm, John J Spinelli, Laurie Smith, Manish Sadarangani, Arianne Albert, Deborah Money, Simon Dobson, Dianne Miller, Marette Lee, Sheona Mitchell-Foster, Mel Krajden, Monika Naus, Gina Ogilvie,

Since 2008, girls in British Columbia (BC), Canada, have been offered HPV vaccination through a school-based, publicly funded immunization program. The oldest birth cohort eligible for the vaccination program was born in 1994 and uptake is on average 63%. To evaluate the impact of the HPV vaccine in BC, ecological ... Read more >>

Int J Cancer (International journal of cancer)
[2021, 149(1):191-199]

Cited: 0 times

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Examining indicators of early menopause following opportunistic salpingectomy: a cohort study from British Columbia, Canada.

Gillian E Hanley, Janice S Kwon, Jessica N McAlpine, David G Huntsman, Sarah J Finlayson, Dianne Miller,

BACKGROUND:The fallopian tube may often be the site of origin for the most common and lethal form of ovarian cancer, high-grade serous ovarian cancer. As a result, many colleges of obstetrics and gynecology, which include the American College of Obstetricians and Gynecologists, are recommending surgical removal of the fallopian tube ... Read more >>

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2020, 223(2):221.e1-221.e11]

Cited: 2 times

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Screening for Anal Cancer in Women With a History of Vulvar High-Grade Squamous Intraepithelial Lesions.

Lily Proctor, Troy Grennan, Arianne Albert, Dianne Miller, Leslie Sadownik, Marette Lee,

<h4>Objectives</h4>The primary obkective was to determine the prevalence of (a) a positive anal cancer screen and (b) histological anal high-grade squamous intraepithelial lesion (HSIL) in women undergoing surveillance for previously diagnosed and treated human papillomavirus (HPV)-associated vulvar HSIL. The secondary objective was to determine the patients' acceptability of the screen.<h4>Materials ... Read more >>

J Low Genit Tract Dis (Journal of lower genital tract disease)
[2019, 23(4):265-271]

Cited: 1 time

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Submillimeter diameter rotary-pullback fiber-optic endoscope for narrowband red-green-blue reflectance, optical coherence tomography, and autofluorescence in vivo imaging.

Andrea Louise Buenconsejo, Geoffrey Hohert, Max Manning, Elham Abouei, Reid Tingley, Ian Janzen, Jessica McAlpine, Dianne Miller, Anthony Lee, Pierre Lane, Calum MacAulay,

A fiber-based endoscopic imaging system combining narrowband red-green-blue (RGB) reflectance with optical coherence tomography (OCT) and autofluorescence imaging (AFI) has been developed. The system uses a submillimeter diameter rotary-pullback double-clad fiber imaging catheter for sample illumination and detection. The imaging capabilities of each modality are presented and demonstrated with images ... Read more >>

J Biomed Opt (Journal of biomedical optics)
[2019, 25(3):1-7]

Cited: 1 time

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Evolution of genetic assessment for BRCA-associated gynaecologic malignancies: a Canadian multisociety roadmap.

Jeanna M McCuaig, Tracy L Stockley, Patricia Shaw, Michael Fung-Kee-Fung, Alon D Altman, James Bentley, Marcus Q Bernardini, Beatrice Cormier, Hal Hirte, Katharina Kieser, Andree MacMillan, Wendy S Meschino, Karen Panabaker, Renee Perrier, Diane Provencher, Kasmintan A Schrader, Kimberly Serfas, Eva Tomiak, Nora Wong, Sean S Young, Walter Henri Gotlieb, Paul Hoskins, Raymond H Kim, ,

The landscape of genetic testing in ovarian cancer patients has changed dramatically in recent years. The therapeutic benefits of poly ADP-ribose polymerase (PARP) inhibitors in treatment of <i>BRCA1/2</i>-related ovarian cancers has resulted in an increased demand and urgency for genetic testing results, while technological developments have led to widespread use ... Read more >>

J Med Genet (Journal of medical genetics)
[2018, 55(9):571-577]

Cited: 11 times

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Outcomes of Conservative Management of High Grade Squamous Intraepithelial Lesions in Young Women.

Marette H Lee, Sarah J Finlayson, Ksenia Gukova, Gillian Hanley, Dianne Miller, Leslie Ann Sadownik,

<h4>Objective</h4>The aim of the study was to determine regression rates of cervical intraepithelial neoplasia (CIN) 2 and 3 in women younger than 24 years, followed conservatively for up to 24 months.<h4>Materials and methods</h4>This is a retrospective chart review of colposcopy patients in clinic database based on the following: (1) younger ... Read more >>

J Low Genit Tract Dis (Journal of lower genital tract disease)
[2018, 22(3):212-218]

Cited: 3 times

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Extending the safety evidence for opportunistic salpingectomy in prevention of ovarian cancer: a cohort study from British Columbia, Canada.

Gillian E Hanley, Janice S Kwon, Sarah J Finlayson, David G Huntsman, Dianne Miller, Jessica N McAlpine,

BACKGROUND:Recent evidence has suggested that the fallopian tube may often be the site of origin for the most common and lethal form of ovarian cancer. As a result, many Colleges of Obstetrics and Gynecology, including the American College of Obstetricians and Gynecology, are recommending surgical removal of the fallopian tube ... Read more >>

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2018, 219(2):172.e1-172.e8]

Cited: 4 times

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Changing Clinical Practice: Evaluation of Implementing Recommendations for Opportunistic Salpingectomy in British Columbia and Ontario.

Bryn Lander, Elizabeth Wilcox, Jessica N McAlpine, Sarah J Finlayson, David G Huntsman, Dianne Miller, Gillian E Hanley,

OBJECTIVE:The aim of the study was to explore the factors that contributed to the adoption of opportunistic salpingectomies (removal of fallopian at the time of hysterectomy or in lieu of tubal ligation) by gynecologic surgeons in British Columbia (where a knowledge translation initiative took place) and in Ontario (a comparator ... Read more >>

Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2018, 28(6):1101-1107]

Cited: 2 times

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A population-based analysis of germline BRCA1 and BRCA2 testing among ovarian cancer patients in an era of histotype-specific approaches to ovarian cancer prevention.

Gillian E Hanley, Jessica N McAlpine, Dianne Miller, David Huntsman, Kasmintan A Schrader, C Blake Gilks, Gillian Mitchell,

<h4>Background</h4>Identifying female carriers of BRCA1 and BRCA2 mutations is imperative for prevention of ovarian cancer and breast cancer. There are five major histologic subtypes of ovarian cancer and high grade serous cancer (the most common) is reported in 75-100% of BRCA1 and BRCA2 mutation carriers. We examined histology-based referral to ... Read more >>

BMC Cancer (BMC cancer)
[2018, 18(1):254]

Cited: 6 times

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HPV-independent Differentiated Vulvar Intraepithelial Neoplasia (dVIN) is Associated With an Aggressive Clinical Course.

Jessica N McAlpine, So Youn Kim, Ardalan Akbari, Sima Eshragh, Miriam Reuschenbach, Magnus von Knebel Doeberitz, Elena S Prigge, Suzanne Jordan, Naveena Singh, Dianne M Miller, C Blake Gilks,

Differentiated vulvar intrapeithelial neoplasia (dVIN) is an human papillomavirus (HPV)-independent precursor of squamous cell carcinoma (SCC), and the aim of this study was to better characterize its natural history. Cases of dVIN were identified from the pathology archives. Outcomes of patients with dVIN only, without associated invasive SCC, were compared ... Read more >>

Int J Gynecol Pathol (International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists)
[2017, 36(6):507-516]

Cited: 6 times

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Human papillomavirus (HPV)-independent vulvar squamous cell carcinoma has a worse prognosis than HPV-associated disease: a retrospective cohort study.

Jessica N McAlpine, Samuel C Y Leung, Angela Cheng, Dianne Miller, Aline Talhouk, C Blake Gilks, Anthony N Karnezis,

<h4>Aims</h4>Vulvar squamous cell carcinoma (VSCC) can be subdivided by human papillomavirus (HPV) status into two clinicopathological entities. Studies on the prognostic significance of HPV in VSCC are discordant.<h4>Methods and results</h4>We performed a retrospective analysis of overall survival (OS), disease-specific survival (DSS) and progression-free survival (PFS) in 217 patients with VSCC. ... Read more >>

Histopathology (Histopathology)
[2017, 71(2):238-246]

Cited: 15 times

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Fluorescence confocal endomicroscopy of the cervix: pilot study on the potential and limitations for clinical implementation.

Colin Schlosser, Nico Bodenschatz, Sylvia Lam, Marette Lee, Jessica N McAlpine, Dianne M Miller, Dirk J T Van Niekerk, Michele Follen, Martial Guillaud, Calum E MacAulay, Pierre M Lane,

Current diagnostic capabilities and limitations of fluorescence endomicroscopy in the cervix are assessed by qualitative and quantitative image analysis. Four cervical tissue types are investigated: normal columnar epithelium, normal and precancerous squamous epithelium, and stromal tissue. This study focuses on the perceived variability within and the subtle differences between the ... Read more >>

J Biomed Opt (Journal of biomedical optics)
[2016, 21(12):126011]

Cited: 10 times

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The performance and safety of bilateral salpingectomy for ovarian cancer prevention in the United States.

Gillian Elizabeth Hanley, Jessica Nell McAlpine, Celeste Leigh Pearce, Dianne Miller,

<h4>Background</h4>Ovarian cancer is the leading cause of death due to gynecologic malignancy and the fifth most common cause of cancer deaths in developed countries. Recent evidence has indicated that the most common and lethal form of ovarian cancer originates in the distal fallopian tube, and recommendations for surgical removal of ... Read more >>

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2017, 216(3):270.e1-270.e9]

Cited: 17 times

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Integrating Quantitative and Qualitative Methods to Evaluate an Online Psychoeducational Program for Sexual Difficulties in Colorectal and Gynecologic Cancer Survivors.

Lori A Brotto, Cara R Dunkley, Erin Breckon, Jeanne Carter, Carl Brown, Judith Daniluk, Dianne Miller,

Sexual health is an integral component of quality of life for cancer survivors, and is often negatively impacted by treatment. Geographic limitations often prohibit survivors from accessing sexual health programs designed to address their needs. This study examined the efficacy of an online, 12-week psychoeducational program, which included elements of ... Read more >>

J Sex Marital Ther (Journal of sex & marital therapy)
[2017, 43(7):645-662]

Cited: 6 times

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Primary site assignment in tubo-ovarian high-grade serous carcinoma: Consensus statement on unifying practice worldwide.

Naveena Singh, C Blake Gilks, Lynn Hirschowitz, Sean Kehoe, Iain A McNeish, Dianne Miller, Raj Naik, Nafisa Wilkinson, W Glenn McCluggage,

Gynecol Oncol (Gynecologic oncology)
[2016, 141(2):195-198]

Cited: 27 times

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Quantification of confocal fluorescence microscopy for the detection of cervical intraepithelial neoplasia.

Fahime Sheikhzadeh, Rabab K Ward, Anita Carraro, Zhao Yang Chen, Dirk van Niekerk, Dianne Miller, Tom Ehlen, Calum E MacAulay, Michele Follen, Pierre M Lane, Martial Guillaud,

<h4>Background</h4>Cervical cancer remains a major health problem, especially in developing countries. Colposcopic examination is used to detect high-grade lesions in patients with a history of abnormal pap smears. New technologies are needed to improve the sensitivity and specificity of this technique. We propose to test the potential of fluorescence confocal ... Read more >>

Biomed Eng Online (Biomedical engineering online)
[2015, 14:96]

Cited: 6 times

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Experiencing Health Advocacy During Cervical Cancer Awareness Week: A National Initiative for Obstetrics and Gynaecology Residents.

Glenn Posner, Sarah Finlayson, Vilma Luna, Dianne Miller, Michael Fung-Kee-Fung,

<h4>Objective</h4>The Royal College of Physicians and Surgeons of Canada requires that residents demonstrate competence in health advocacy (HA). We sought to develop and implement a national educational module for obstetrics and gynaecology residents to address the role of HA. This pilot program was centred on cervical cancer prevention, which lends ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2015, 37(7):633-638]

Cited: 1 time

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Reduction in cervical intraepithelial neoplasia in young women in British Columbia after introduction of the HPV vaccine: An ecological analysis.

Gina S Ogilvie, Monika Naus, Deborah M Money, Simon R Dobson, Dianne Miller, Mel Krajden, Dirk J van Niekerk, Andrew J Coldman,

We report on the rates of cervical intraepithelial neoplasia (CIN) in young women aged 15-22 years of age in British Columbia before and after the introduction of an HPV vaccine program. Rates of cervical intraepithelial neoplasia (CIN) 2+ for each age stratum (15-22) in the calendar years 2004-2012 for the ... Read more >>

Int J Cancer (International journal of cancer)
[2015, 137(8):1931-1937]

Cited: 17 times

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Vulvar Acanthosis With Altered Differentiation (VAAD): Report of a Case With Progression to Poorly Differentiated Carcinoma Over a 5-Yr Period.

Raeda Al-Bannai, Dianne Miller, Leslie Sadownik, C Blake Gilks,

Vulvar acanthosis with altered differentiation is an uncommon proliferation of the vulvar squamous epithelium that is typically seen in association with verrucous carcinoma, and may represent an early phase of non-HPV-related squamous neoplastic transformation. We report a case of vulvar acanthosis with altered differentiation that, over a 5-yr period, progressed ... Read more >>

Int J Gynecol Pathol (International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists)
[2015, 34(4):385-389]

Cited: 4 times

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Projected Impact of HPV and LBC Primary Testing on Rates of Referral for Colposcopy in a Canadian Cervical Cancer Screening Program.

Andrew J Coldman, Norm Phillips, Dirk van Niekerk, Laurie Smith, Mel Krajden, Darrel Cook, David J Quinlan, Thomas Ehlen, Dianne Miller, Gavin C E Stuart, Stuart Peacock, Ruth Elwood Martin, Eduardo L Franco, Gina Ogilvie,

<h4>Objective</h4>To estimate the impact of implementing primary human papilloma virus liquid-based cytology (LBC) screening on four-year rates of referral for colposcopy in the British Columbia screening program.<h4>Methods</h4>We used data on referral for colposcopy from an RCT (HPV FOCAL) comparing HPV testing every four years with LBC testing every two years. ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2015, 37(5):412-420]

Cited: 7 times

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Costs and benefits of opportunistic salpingectomy as an ovarian cancer prevention strategy.

Janice S Kwon, Jessica N McAlpine, Gillian E Hanley, Sarah J Finlayson, Trevor Cohen, Dianne M Miller, C Blake Gilks, David G Huntsman,

<h4>Objective</h4>To conduct a cost-effectiveness analysis of opportunistic salpingectomy (elective salpingectomy at hysterectomy or instead of tubal ligation).<h4>Methods</h4>A Markov Monte Carlo simulation model estimated the costs and benefits of opportunistic salpingectomy in a hypothetical cohort of women undergoing hysterectomy for benign gynecologic conditions or surgical sterilization. The primary outcome measure was ... Read more >>

Obstet Gynecol (Obstetrics and gynecology)
[2015, 125(2):338-345]

Cited: 39 times

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Time for a level playing field: inequalities in regulatory/approval processes—the example of bevacizumab in epithelial ovarian cancer.

Paul J Hoskins, Michael Fung-Kee-Fung, Dianne Miller, Walter Gotlieb,

J Clin Oncol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2015, 33(14):1539-1542]

Cited: 2 times

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Technical update on tissue morcellation during gynaecologic surgery: its uses, complications, and risks of unsuspected malignancy.

Sukhbir S Singh, Stephanie Scott, Olga Bougie, Nicholas Leyland, , Nicholas Leyland, Wendy Wolfman, Catherine Allaire, Alaa Awadalla, Annette Bullen, Margaret Burnett, Susan Goldstein, Madeleine Lemyre, Violaine Marcoux, Frank Potestio, David Rittenberg, Sukhbir S Singh, Grace Yeung, , Paul Hoskins, Dianne Miller, Walter Gotlieb, Marcus Bernardini, Laura Hopkins,

<h4>Objective</h4>To review the use of tissue morcellation in minimally invasive gynaecological surgery.<h4>Outcomes</h4>Morcellation may be used in gynaecological surgery to allow removal of large uterine specimens, providing women with a minimally invasive surgical option. Adverse oncologic outcomes of tissue morcellation should be mitigated through improved patient selection, preoperative investigations, and novel ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2015, 37(1):68-81]

Cited: 13 times

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The State of Antimicrobial Stewardship in Michigan: Results of a Statewide Survey on Antimicrobial Stewardship Efforts in Acute Care Hospitals.

Curtis D Collins, Dianne E Miller, Rachel M Kenney, Ryan P Mynatt, Michael D Tiberg, Kelli Cole, Jesse D Sutton, Jason M Pogue,

Hosp Pharm (Hospital pharmacy)
[2015, 50(3):180-184]

Cited: 4 times

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Attribution of 12 high-risk human papillomavirus genotypes to infection and cervical disease.

Elmar A Joura, Kevin A Ault, F Xavier Bosch, Darron Brown, Jack Cuzick, Daron Ferris, Suzanne M Garland, Anna R Giuliano, Mauricio Hernandez-Avila, Warner Huh, Ole-Erik Iversen, Susanne K Kjaer, Joaquin Luna, Dianne Miller, Joseph Monsonego, Nubia Munoz, Evan Myers, Jorma Paavonen, Punnee Pitisuttithum, Marc Steben, Cosette M Wheeler, Gonzalo Perez, Alfred Saah, Alain Luxembourg, Heather L Sings, Christine Velicer,

<h4>Background</h4>We estimated the prevalence and incidence of 14 human papillomavirus (HPV) types (6/11/16/18/31/33/35/39/45/51/52/56/58/59) in cervicovaginal swabs, and the attribution of these HPV types in cervical intraepithelial neoplasia (CIN), and adenocarcinoma in situ (AIS), using predefined algorithms that adjusted for multiple-type infected lesions.<h4>Methods</h4>A total of 10,656 women ages 15 to 26 ... Read more >>

Cancer Epidemiol Biomarkers Prev (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology)
[2014, 23(10):1997-2008]

Cited: 64 times

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