Full Text Journal Articles by
Author Dhaval M Patel

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Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP~T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination.

Miia Virta, Anu Soininen, Dhaval M Patel, Céline Petit, Cynthia Tabar, Olga Lyabis,

Anti-hepatitis B (HBs) antibody persistence and hepatitis B challenge were evaluated at 6 years of age following vaccination of fully liquid DTaP-IPV-HB-PRP~T or reconstituted DTaP-IPV-HB//PRP~T at 3, 5, 11-12 months of age. At 6 years, 53.8% and 73.5% had seroprotective anti-HBs antibodies (≥10 mIU/mL), increasing to 96.7% and 95.9% postchallenge, ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(1):e28-e30]

Cited: 0 times

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Safety and immunogenicity of Clostridium difficile toxoid vaccine in Japanese adults.

Osamu Matsuoka, Dhaval M Patel, Shin Sasaki, Hayato Oka, Toru Sasaki, Patricia J Pietrobon, Thelma Laot, Alain Bouckenooghe, Josemund Menezes, Guy de Bruyn,

This was a randomized, placebo-controlled, Phase I/II study conducted in a Japanese cohort to assess the safety and immunogenicity of Clostridium difficile vaccine (the same formulation as that used in the ongoing global Phase III study). Healthy Japanese adults aged 40-75 years were randomized to receive either C. difficile vaccine (N ... Read more >>

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2018, 14(2):322-328]

Cited: 3 times

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Defining the optimal formulation and schedule of a candidate toxoid vaccine against Clostridium difficile infection: A randomized Phase 2 clinical trial.

Guy de Bruyn, Jamshid Saleh, David Workman, Richard Pollak, Victor Elinoff, Neil J Fraser, Gigi Lefebvre, Mark Martens, Richard E Mills, Richard Nathan, Miguel Trevino, Martin van Cleeff, Ginamarie Foglia, Ayca Ozol-Godfrey, Dhaval M Patel, Patricia J Pietrobon, Richard Gesser, ,

<h4>Background</h4>Clostridium difficile, a major cause of nosocomial and antibiotic-associated diarrhea, carries a significant disease and cost burden. This study aimed to select an optimal formulation and schedule for a candidate toxoid vaccine against C. difficile toxins A and B.<h4>Methods</h4>Randomized, placebo-controlled, two-stage, Phase 2 study in a total of 661 adults ... Read more >>

Vaccine (Vaccine)
[2016, 34(19):2170-2178]

Cited: 29 times

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MHC class II biosynthesis by activated rat CD4+ T cells: development of repression in vitro and modulation by APC-derived signals.

Mark D Mannie, John G Dawkins, Mindi R Walker, Barbara A Clayson, Dhaval M Patel,

This study focused on synthesis of MHC class II glycoproteins (MHCII) by rat CD4(+) T-helper cells. During activation in Con A and IL-2, purified rat splenic CD4(+) T cells expressed abundant surface MHCII together with transcripts for I-A alpha/beta, invariant chain, and the type III and type IV MHC class ... Read more >>

Cell Immunol (Cellular immunology)
[2004, 230(1):33-43]

Cited: 5 times

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