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Author Deli Wang

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Smurf1-targeting miR-19b-3p-modified BMSCs combined PLLA composite scaffold to enhance osteogenic activity and treat critical-sized bone defects.

Ao Xiong, Yijun He, Liang Gao, Guoqing Li, Jian Weng, Bin Kang, Deli Wang, Hui Zeng,

Over the past few years, tissue-engineering technology provided a new direction for bone defects therapy, which involved developing applicable biological materials composite with seed cells to repair bone defects tissue. However, as one of the commonest seed cells for tissue engineering, BMSCs (bone marrow mesenchymal stem cells), are still lacking ... Read more >>

Biomater Sci (Biomaterials science)
[2020, 8(21):6069-6081]

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Effects of grazing on C:N:P stoichiometry attenuate from soils to plants and insect herbivores in a semi-arid grassland.

Nazim Hassan, Xiaofei Li, Jianyong Wang, Hui Zhu, Petri Nummi, Deli Wang, Deborah Finke, Zhiwei Zhong,

Understanding the processing of limiting nutrients among organisms is an important goal of community ecology. Less known is how human disturbances may alter the stoichiometric patterns among organisms from different trophic levels within communities. Here, we investigated how livestock grazing affects the C:N:P ecological stoichiometry of soils, plants (Leymus chinensis), ... Read more >>

Oecologia (Oecologia)
[2021, :]

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Introduced ecological engineers drive behavioral changes of grasshoppers, consequently linking to its abundance in two grassland plant communities.

Deli Wang, Venuste Nkurunziza, Nicholas A Barber, Hui Zhu, Jingting Wang,

Introduced ecosystem engineers are expected to have extensive ecological impacts on a broad range of resident biota by altering the physical-chemical structure of ecosystems. Livestock that are potentially important introduced ecosystem engineers in grassland systems could create and/or modify habitats for native plant-dwelling insects. Yet, there is little knowledge of ... Read more >>

Oecologia (Oecologia)
[2021, :]

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Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial.

Günter U Höglinger, Irene Litvan, Nuno Mendonca, Deli Wang, Hui Zheng, Beatrice Rendenbach-Mueller, Hoi-Kei Lon, Ziyi Jin, Nahome Fisseha, Kumar Budur, Michael Gold, Davis Ryman, Hana Florian, ,

<h4>Background</h4>Progressive supranuclear palsy is a neurodegenerative disorder associated with tau protein aggregation. Tilavonemab (ABBV-8E12) is a monoclonal antibody that binds to the N-terminus of human tau. We assessed the safety and efficacy of tilavonemab for the treatment of progressive supranuclear palsy.<h4>Methods</h4>We did a phase 2, multicentre, randomised, placebo-controlled, double-blind study ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2021, 20(3):182-192]

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Soil engineering by ants facilitates plant compensation for large herbivore removal of aboveground biomass.

Zhiwei Zhong, Xiaofei Li, Dirk Sanders, Yiming Liu, Ling Wang, Yvette K Ortega, Dean E Pearson, Deli Wang,

The interplay between top-down and bottom-up processes determines ecosystem productivity. Yet, the factors that mediate the balance between these opposing forces remain poorly understood. Furthering this challenge, complex and often cryptic factors like ecosystem engineering and trait-mediated interactions may play major roles in mediating the outcomes of top-down and bottom-up ... Read more >>

Ecology (Ecology)
[2021, :e03312]

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The Difference of Acetabular Cup Orientation Between Two Surgical Sides After Primary Total Hip Arthroplasty by Right-handed Surgeons

Ao Xiong, su liu, Guoqing Li, Jian Weng, Deli Wang, Hui Zeng,

<h4>Background: </h4> We performed the retrospective cohort study to compare the acetabular cup orientation, including anteversion angle (AA) and inclination angle (IA), of dominant hand side and non-dominant hand side after primary total hip arthroplasty (THA) by right-handed orthopedic surgeons. <h4>Methods: </h4> Between January 2018 and December 2018, 290 patients ... Read more >>

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Nitrogen and litter addition decreased sexual reproduction and increased clonal propagation in grasslands.

Zimeng Li, Jinfeng Wu, Qing Han, Kunyan Nie, Jiani Xie, Yufei Li, Xinyu Wang, Haibo Du, Deli Wang, Jushan Liu,

The trade-offs between sexual reproduction and clonal propagation are of great significance in terms of ecology and evolution for clonal plants, and they vary with environmental change. Nitrogen (N) deposition can increase litter accumulation in grassland and promote litter decomposition and consequently increase nutrient availability. However, the response of plant ... Read more >>

Oecologia (Oecologia)
[2021, 195(1):131-144]

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Effect of enhanced recovery after surgery in the managements of ankle fracture patients: A single-center retrospective cohort study

Yuefeng Yao, Guoqing Li, Su Liu, Ao Xiong, Chang Xu, Deli Wang, Hui Zeng,

<h4>Background: </h4> Ankle fracture is common and the treatment is embarrassed. Enhanced Recovery After Surgery (ERAS) has been successfully adopted for the improvement of efficacy and quality. However, application of ERAS in ankle fracture patients especially at the early stage is variable and remains to be clarified. We intent to ... Read more >>

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Effect of enhanced recovery after surgery in the managements of ankle fracture patients: a single-center retrospective cohort study

Yuefeng Yao, Guoqing Li, Su Liu, Ao Xiong, Chang Xu, Deli Wang, Hui Zeng,

<h4>Background: </h4> Ankle fracture is common and the treatment is embarrassed. Enhanced Recovery After Surgery (ERAS) has been successfully adopted for the improvement of efficacy and quality. However, application of ERAS in ankle fracture patients especially at the early stage is variable and remains to be clarified. We intent to ... Read more >>

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The strategies of perioperative management in orthopedic department during the pandemic of COVID-19.

Hui Zeng, Guoqing Li, Jian Weng, Ao Xiong, Chang Xu, Yifei Yang, Deli Wang,

<h4>Background</h4>Coronavirus disease 2019 (COVID-19) has broken out and spread rapidly nationwide at the beginning of 2020, which has brought huge impacts to people and work. The current situation of prevention and control is severe and urges guidance for clinicians, especially for medical systems. In the hope of providing a reference ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2020, 15(1):474]

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The strategies of perioperative management in orthopedic department during the pandemic of COVID-19

Hui Zeng, Guoqing Li, Jian Weng, Ao Xiong, Chang Xu, Yifei Yang, Deli Wang,

<h4>Background: </h4> Coronavirus disease 2019 (COVID-19) broken out and spread rapidly nationwide at the beginning of 2020, which has brought huge impacts to people and work. The current situation of prevention and control is severe and urge guidance for clinicians, especially for medical systems. In the hope of providing a ... Read more >>

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BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy.

Zetao Ma, Deli Wang, Jian Weng, Sheng Zhang, Yuanshi Zhang,

<h4>Background</h4>Inflammation and apoptosis of chondrocytes are the pathological bases of osteoarthritis. Autophagy could alleviate the symptoms of inflammation and apoptosis. Previous study has shown that BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) can induce the occurrence and development of autophagy. However, it is unknown whether autophagy induced by BNIP3 can ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2020, 15(1):284]

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BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy

Zetao Ma, Deli Wang, Jian Weng, Sheng Zhang, Yuanshi Zhang,

<h4>Background: </h4> Inflammation and apoptosis of chondrocytes are the pathological basis of osteoarthritis. Autophagy could alleviate the symptoms of inflammation and apoptosis. Previous study has shown that BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) can induce the occurrence and development of autophagy. However, it is unknown whether autophagy induced ... Read more >>

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Worldwide effects of non-native species on species-area relationships.

Qinfeng Guo, Xiaoyu Cen, Ruiyan Song, Michael L McKinney, Deli Wang,

Non-native species have invaded most parts of the world, and the invasion process is expected to continue and accelerate. Because many invading non-native species are likely to become permanent inhabitants, future consideration of species-area relationships (SARs) should account for non-native species, either separately or jointly with native species. If non-native ... Read more >>

Conserv Biol (Conservation biology : the journal of the Society for Conservation Biology)
[2020, :]

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Patient Characteristics and Medical Provider Factors Are Associated With Length of Stay in Total Hip Arthroplasty Patients: a Retrospective Chinese Cohort Study

Hui Zeng, Guoqing Li, Fei Yu, Jian Weng, Ao Xiong, Qiang Fu, Yucong Zeng, Fangxi Wang, Chang Xu, Deli Wang,

<h4>Background: </h4> Total hip arthroplasty (THA) is a successful treatment in the improvement of quality of life. Diagnosis-related groups (DRGs) payment has a significant impact on the hospital market in China and length of stay (LOS) is one of its crucial manifestations. Patient characteristics and medical provider factors can affect ... Read more >>

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Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway.

Yang Zhou, Hongyu Lian, Kexin Liu, Deli Wang, Xuelian Xiu, Zhang Sun,

Bone graft defects may lead to dysfunction of bone regeneration and metabolic disorders of bone mesenchymal stem cells (BMSCs). Puerarin has demonstrated pharmacological activities in the treatment of human metabolic diseases. The purpose of the present study was to investigate the role of puerarin and to explore its possible protective ... Read more >>

Int J Mol Med (International journal of molecular medicine)
[2020, 46(1):239-251]

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Turning Waste into Treasure: Regulating the Oxygen Corrosion on Fe Foam for Efficient Electrocatalysis.

Xupo Liu, Mingxing Gong, Dongdong Xiao, Shaofeng Deng, Jianing Liang, Tonghui Zhao, Yun Lu, Tao Shen, Jian Zhang, Deli Wang,

Iron corrosion causes a great damage to the economy due to the function attenuation of iron-based devices. However, the corrosion products can be used as active materials for some electrocatalytic reactions, such as oxygen evolution reaction (OER). Herein, the oxygen corrosion on Fe foams (FF) to synthesize effective self-supporting electrocatalysts ... Read more >>

Small (Small (Weinheim an der Bergstrasse, Germany))
[2020, 16(24):e2000663]

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Interactive effects of exogenous melatonin and Rhizophagus intraradices on saline-alkaline stress tolerance in Leymus chinensis.

Yurong Yang, Yaping Cao, Zhenxin Li, Anastasiia Zhukova, Songtao Yang, Jinlong Wang, Zhanhui Tang, Yonghong Cao, Yifei Zhang, Deli Wang,

Melatonin, a ubiquitous molecule found in almost all organisms, is considered an important regulator in plant growth. However, little is known about the interactive effect of melatonin and arbuscular mycorrhizal (AM) fungi on plant resistance against soil salinity and alkalinity. To fill in such a gap in knowledge, we conducted ... Read more >>

Mycorrhiza (Mycorrhiza)
[2020, 30(2-3):357-371]

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Paracoccus aurantiacus sp. nov., isolated from shallow-sea hydrothermal systems off Kueishantao Island.

Jianing Ye, Dan Lin, Mu Zhang, Ta-Hui Lin, Jia Sun, Deli Wang, Kai Tang,

An orange-pigmented, short-rod-shaped, aerobic and non-motile bacterial strain, designated TK008T, was isolated from the shallow-sea hydrothermal systems off Kueishantao Island in Taiwan, China, and it was studied by using a polyphasic taxonomic approach. Cells were Gram-stain-negative, and catalase- and oxidase-positive. Strain TK008T exhibited highest 16S rRNA gene sequence similarity of ... Read more >>

Int J Syst Evol Microbiol (International journal of systematic and evolutionary microbiology)
[2020, 70(4):2554-2559]

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Rational Design and Engineering of Nanomaterials Derived from Prussian Blue and Its Analogs for Electrochemical Water Splitting.

Cuijuan Xuan, Jian Zhang, Jie Wang, Deli Wang,

Electrochemical water splitting (EWS) is a sustainable and promising technology for producing hydrogen as an ideal energy carrier to address environmental and energy issues. Developing highly-efficient electrocatalysts for hydrogen and oxygen evolution reactions (HER and OER) is critical for increasing the efficiency of water electrolysis. Recently, nanomaterials derived from Prussian ... Read more >>

Chem Asian J (Chemistry, an Asian journal)
[2020, 15(7):958-972]

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Polymerase chain reaction - surface-enhanced Raman spectroscopy (PCR-SERS) method for gene methylation level detection in plasma.

Xiaozhou Li, Tianyue Yang, Caesar Siqi Li, Youtao Song, Deli Wang, Lili Jin, Hong Lou, Wei Li,

Gene promoter hypermethylation is a vital step in tumorigenesis. This paper set out to explore the use of polymerase chain reaction - surface-enhanced Raman spectroscopy (PCR-SERS) for the detection of gene methylation levels, with a focus on cancer diagnosis. Methods: PCR with methylation independent primers were used on DNA samples ... Read more >>

Theranostics (Theranostics)
[2020, 10(2):898-909]

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Food and habitat provisions jointly determine competitive and facilitative interactions among distantly related herbivores

Duofeng Pan, Xincheng Li, Kejia De, Ling Wang, Deli Wang, Qinfeng Guo, Chao Gao, Zhiwei Zhong, Hui Zhu, Zhongbao Shen, Timothy R Seastedt,

Interactions between distantly related herbivores exert powerful influences on ecosystems, but most studies to date have only considered unidirectional effects. Few have simultaneously examined the mutual effects that vertebrate herbivores and insect herbivores have on one another. We conducted a set of manipulative experiments to evaluate the potential competition and ... Read more >>

(Functional Ecology)
[2019, 33(12):2381-2390]

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miR-1225-5p Functions as a Tumor Suppressor in Osteosarcoma by Targeting Sox9.

Weifei Zhang, Liangchen Wei, Weibei Sheng, Bin Kang, Deli Wang, Hui Zeng,

microRNA plays an important role in the development of tumors, including osteosarcoma. However, the role of miR-1225-5p in osteosarcoma is currently unclear. First, we found that miR-1225-5p was downregulated in osteosarcoma cells relative to its levels in normal bone tissue by analyzing GSE28423 data in the GEO database. Using GSE39040, ... Read more >>

DNA Cell Biol (DNA and cell biology)
[2020, 39(1):78-91]

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Hierarchical Bimetallic Ni-Co-P Microflowers with Ultrathin Nanosheet Arrays for Efficient Hydrogen Evolution Reaction over All pH Values.

Xupo Liu, Shaofeng Deng, Dongdong Xiao, Mingxing Gong, Jianing Liang, Tonghui Zhao, Tao Shen, Deli Wang,

Designing efficient nonprecious catalysts with pH-universal hydrogen evolution reaction (HER) performance is of importance for boosting water splitting. Herein, a self-template strategy based on Ni-Co-glycerates is developed to prepare bimetallic Ni-Co-P microflowers with ultrathin nanosheet arrays. The highly porous core-shell structure gives rise to affluent mass transfer channels and availably ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2019, 11(45):42233-42242]

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Reply to Liang and Gornish: Climate and livestock grazing jointly regulate grassland ecosystem multifunctionality.

Ling Wang, Deli Wang,

Proc Natl Acad Sci U S A (Proceedings of the National Academy of Sciences of the United States of America)
[2019, 116(48):23889-23890]

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