Full Text Journal Articles by
Author Deepti Pilli

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Effects of the Positive Threshold and Data Analysis on Human MOG Antibody Detection by Live Flow Cytometry.

Fiona Tea, Deepti Pilli, Sudarshini Ramanathan, Joseph A Lopez, Vera Merheb, Fiona X Z Lee, Alicia Zou, Ganesha Liyanage, Chelsea B Bassett, Selina Thomsen, Stephen W Reddel, Michael H Barnett, David A Brown, Russell C Dale, Fabienne Brilot, ,

Human autoantibodies targeting myelin oligodendrocyte glycoprotein (MOG Ab) have become a useful clinical biomarker for the diagnosis of a spectrum of inflammatory demyelinating disorders. Live cell-based assays that detect MOG Ab against conformational MOG are currently the gold standard. Flow cytometry, in which serum binding to MOG-expressing cells and control ... Read more >>

Front Immunol (Frontiers in immunology)
[2020, 11:119]

Cited: 0 times

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Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination.

Fiona Tea, Joseph A Lopez, Sudarshini Ramanathan, Vera Merheb, Fiona X Z Lee, Alicia Zou, Deepti Pilli, Ellis Patrick, Anneke van der Walt, Mastura Monif, Esther M Tantsis, Eppie M Yiu, Steve Vucic, Andrew P D Henderson, Anthony Fok, Clare L Fraser, Jeanette Lechner-Scott, Stephen W Reddel, Simon Broadley, Michael H Barnett, David A Brown, Jan D Lunemann, Russell C Dale, Fabienne Brilot, ,

Over recent years, human autoantibodies targeting myelin oligodendrocyte glycoprotein (MOG Ab) have been associated with monophasic and relapsing central nervous system demyelination involving the optic nerves, spinal cord, and brain. While the clinical relevance of MOG Ab detection is becoming increasingly clear as therapeutic and prognostic differences from multiple sclerosis ... Read more >>

Acta Neuropathol Commun (Acta neuropathologica communications)
[2019, 7(1):145]

Cited: 1 time

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Expanding Role of T Cells in Human Autoimmune Diseases of the Central Nervous System.

Deepti Pilli, Alicia Zou, Fiona Tea, Russell C Dale, Fabienne Brilot,

It is being increasingly recognized that a dysregulation of the immune system plays a vital role in neurological disorders and shapes the treatment of the disease. Aberrant T cell responses, in particular, are key in driving autoimmunity and have been traditionally associated with multiple sclerosis. Yet, it is evident that ... Read more >>

Front Immunol (Frontiers in immunology)
[2017, 8:652]

Cited: 8 times

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Dopamine-2 receptor extracellular N-terminus regulates receptor surface availability and is the target of human pathogenic antibodies from children with movement and psychiatric disorders.

Nese Sinmaz, Fiona Tea, Deepti Pilli, Alicia Zou, Mazen Amatoury, Tina Nguyen, Vera Merheb, Sudarshini Ramanathan, Sandra T Cooper, Russell C Dale, Fabienne Brilot,

Anti-Dopamine-2 receptor (D2R) antibodies have been recently identified in a subgroup of children with autoimmune movement and psychiatric disorders, however the epitope(s) and mechanism of pathogenicity remain unknown. Here we report a major biological role for D2R extracellular N-terminus as a regulator of receptor surface availability, and as a major ... Read more >>

Acta Neuropathol Commun (Acta neuropathologica communications)
[2016, 4(1):126]

Cited: 5 times

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