Full Text Journal Articles by
Author Deborah M Money

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Early Neonatal Meconium Does Not Have a Demonstrable Microbiota Determined through Use of Robust Negative Controls with cpn60-Based Microbiome Profiling.

Scott J Dos Santos, Zahra Pakzad, Chelsea N Elwood, Arianne Y K Albert, Soren Gantt, Amee R Manges, Tim J Dumonceaux, Evelyn J Maan, Janet E Hill, Deborah M Money, ,

Detection of bacterial DNA within meconium is often cited as evidence supporting <i>in utero</i> colonization. However, many studies fail to adequately control for contamination. We aimed to define the microbial content of meconium under properly controlled conditions. DNA was extracted from 141 meconium samples and subjected to <i>cpn</i>60-based microbiome profiling, ... Read more >>

Microbiol Spectr (Microbiology spectrum)
[2021, :e0006721]

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Elevated Blood Mitochondrial DNA in Early Life Among Uninfected Children Exposed to Human Immunodeficiency Virus and Combination Antiretroviral Therapy in utero.

Abhinav Ajaykumar, Mayanne Zhu, Fatima Kakkar, Jason Brophy, Ari Bitnun, Ariane Alimenti, Hugo Soudeyns, Sara Saberi, Arianne Y K Albert, Deborah M Money, Hélène C F Côté, ,

<h4>Background</h4>Combination antiretroviral therapy (cART) during pregnancy prevents vertical transmission, but many antiretrovirals cross the placenta and several can affect mitochondria. Exposure to maternal human immunodeficiency virus (HIV) and/or cART could have long-term effects on children who are HIV exposed and uninfected (CHEU). Our objective was to compare blood mitochondrial DNA ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2021, 223(4):621-631]

Cited: 1 time

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Preterm Birth and Antiretroviral Exposure in Infants HIV-exposed Uninfected.

Micah Piske, Annie Q Qiu, Evelyn J Maan, Laura J Sauvé, John C Forbes, Ariane Alimenti, Patricia A Janssen, Deborah M Money, Hélène C F Côté, ,

<h4>Background</h4>Infants HIV-exposed and uninfected (IHEU) who are born to women living with HIV are at an increased risk of preterm birth (PTB). Antenatal exposure to certain maternal antiretroviral therapy (ART) regimens has been associated with PTB, although existing studies in this domain are limited and report discordant findings. We determined ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(3):245-250]

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Investigation of factors associated with spontaneous preterm birth in pregnant women living with HIV.

Arianne Y K Albert, Chelsea Elwood, Emily C Wagner, Zahra Pakzad, Tessa Chaworth-Musters, Kyra Berg, Julie Van Schalkwyk, Evelyn J Maan, Arezou Azampanah, Elisabeth McClymont, Ariane Alimenti, John C Forbes, Deborah M Money,

<h4>Objective</h4>To investigate factors contributing to preterm birth (PTB), including cART use and clinical and social determinants of health, in women living with HIV (WLWH) from British Columbia, Canada.<h4>Design</h4>Retrospective observational cohort.<h4>Methods</h4>We investigated the effect of cART use and other clinical and demographic factors on spontaneous PTB (sPTB) rates (<37 weeks gestational ... Read more >>

AIDS (AIDS (London, England))
[2020, 34(5):719-727]

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Urinary symptoms and quality of life in women living with HIV: a cross-sectional study.

Maryse Larouche, Arianne Y K Albert, Nancy Lipsky, Sharon Walmsley, Mona Loutfy, Fiona Smaill, Sylvie Trottier, Ari Bitnun, Mark H Yudin, Geoffrey W Cundiff, Deborah M Money,

<h4>Introduction and hypothesis</h4>To determine prevalence and quality of life impact of lower urinary tract symptoms (LUTS) in women living with HIV (WLWH).<h4>Methods</h4>Cross-sectional urinary questionnaires were included in a multicenter national prospective study of the HPV vaccine in WLWH. Demographic and clinical information was abstracted from the parent study. The Urinary ... Read more >>

Int Urogynecol J (International urogynecology journal)
[2021, 32(2):353-358]

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Dynamics of leukocyte telomere length in pregnant women living with HIV, and HIV-negative pregnant women: A longitudinal observational study.

Sara Saberi, Steve E Kalloger, Mayanne M T Zhu, Beheroze Sattha, Evelyn J Maan, Julianne van Schalkwyk, Deborah M Money, Hélène C F Côté, ,

BACKGROUND:HIV-mediated inflammation and immune activation can accelerate telomere attrition. In addition, antiretrovirals can inhibit telomerase, possibly shortening telomeres. We examined the longitudinal dynamics of leukocyte telomere length (LTL) during pregnancy in a unique cohort of women living with HIV (WLWH) treated with combination antiretroviral therapy (cART), and HIV-negative control women. ... Read more >>

PLoS One (PloS one)
[2019, 14(3):e0212273]

Cited: 3 times

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Quasispecies Diversity Is a Major Risk Factor for Vertical Hepatitis C Virus Transmission.

Ariane Larouche, Kimberly-Ann Milton McSween, Virginie Calderon, Sébastien Fauteux-Daniel, Jonathan Boulais, Doris G Ransy, Marc Boucher, Valérie Lamarre, Normand Lapointe, Isabelle Boucoiran, Deborah M Money, Mel Krajden, Armelle Le Campion, Hugo Soudeyns,

<h4>Background</h4>Vertical transmission is the major cause of pediatric hepatitis C virus (HCV) infection. The objective of this study was to better understand HCV pathogenesis in pregnant women and provide insights into risk factors and mechanisms involved in vertical transmission.<h4>Methods</h4>Evolutionary dynamics of HCV variant spectra and HCV-specific neutralizing antibody responses were ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2019, 219(5):760-771]

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Exploring the live birth rates of women living with HIV in British Columbia, Canada.

Clara E Van Ommen, Arianne Y K Albert, Micah Piske, Deborah M Money, Hélène C F Cote, Viviane D Lima, Evelyn J Maan, Ariane Alimenti, Julianne van Schalkwyk, Neora Pick, Melanie C M Murray,

OBJECTIVE:To evaluate the birth rates of women living with HIV (WLWH) compared to the general population in British Columbia (BC), Canada. METHODS:We retrospectively reviewed clinical and population level surveillance data from 1997 to 2015. Live birth rates from 1997 to 2015 among WLWH aged 15-49 years were compared with those ... Read more >>

PLoS One (PloS one)
[2019, 14(2):e0211434]

Cited: 1 time

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Understanding Men's Perceptions of Human Papillomavirus and Cervical Cancer Screening in Kampala, Uganda.

Erin Moses, Heather N Pedersen, Emily C Wagner, Musa Sekikubo, Deborah M Money, Gina S Ogilvie, Sheona M Mitchell-Foster,

<h4>Purpose</h4>This preliminary study explores Ugandan men's knowledge and attitudes about human papillomavirus (HPV), cervical cancer, and screening.<h4>Methods</h4>A local physician led an education session about cervical cancer for 62 men in Kisenyi, Kampala in Uganda. Trained nurse midwives administered surveys to assess knowledge and attitudes before and after the education session.<h4>Results</h4>From ... Read more >>

J Glob Oncol (Journal of global oncology)
[2018, 4:1-9]

Cited: 1 time

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Increased richness and diversity of the vaginal microbiota and spontaneous preterm birth.

Aline C Freitas, Alan Bocking, Janet E Hill, Deborah M Money, ,

<h4>Background</h4>The bacterial community present in the female lower genital tract plays an important role in maternal and neonatal health. Imbalances in this microbiota have been associated with negative reproductive outcomes, such as spontaneous preterm birth (sPTB), but the mechanisms underlying the association between a disturbed microbiota and sPTB remain poorly ... Read more >>

Microbiome (Microbiome)
[2018, 6(1):117]

Cited: 39 times

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Premature Spinal Bone Loss in Women Living with HIV is Associated with Shorter Leukocyte Telomere Length.

Shirin Kalyan, Neora Pick, Alice Mai, Melanie C M Murray, Kristen Kidson, Jackson Chu, Arianne Y K Albert, Hélène C F Côté, Evelyn J Maan, Azita Goshtasebi, Deborah M Money, Jerilynn C Prior,

With advances in combination antiretroviral therapy (cART), people living with HIV are now surviving to experience aging. Evidence suggests that individuals living with HIV are at greater risk for low bone mineral density (BMD), osteoporosis, and fractures. Better understanding of the pathophysiology of bone health in women living with HIV ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2018, 15(5):]

Cited: 2 times

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Vaginal health and hygiene practices and product use in Canada: a national cross-sectional survey.

Sara E Crann, Shannon Cunningham, Arianne Albert, Deborah M Money, Kieran C O'Doherty,

<h4>Background</h4>The vaginal microbiome influences quality of life and health. The composition of vaginal microbiota can be affected by various health behaviors, such as vaginal douching. The purpose of this study was to examine the types and prevalence of diverse vaginal/genital health and hygiene behaviors among participants living in Canada and ... Read more >>

BMC Womens Health (BMC women's health)
[2018, 18(1):52]

Cited: 3 times

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Missed opportunities for prevention of vertical HIV transmission in Canada, 1997-2016: a surveillance study.

Ari Bitnun, Terry Lee, Jason Brophy, Lindy M Samson, Fatima Kakkar, Wendy Vaudry, Ben Tan, Deborah M Money, Joel Singer, Laura J Sauvé, Ariane Alimenti, ,

<h4>Background</h4>Vertical HIV transmission has declined in Canada, but missed opportunities for prevention continue to occur. We sought to determine the adequacy, and changes over time in adequacy, of uptake of maternal and neonatal antiretroviral therapy for the prevention of vertical HIV transmission, and to determine the vertical transmission rate over ... Read more >>

CMAJ Open (CMAJ open)
[2018, 6(2):E202-E210]

Cited: 4 times

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Severe menopausal symptoms associated with reduced adherence to antiretroviral therapy among perimenopausal and menopausal women living with HIV in Metro Vancouver.

Putu K Duff, Deborah M Money, Gina S Ogilvie, Florence Ranville, Mary Kestler, Melissa C Braschel, Neora Pick, Kate Shannon, ,

OBJECTIVES:Although more women living with HIV (WLWH) are entering midlife, the experiences of perimenopausal and menopausal WLWH, including the effects of menopausal symptoms severity, remain understudied. This study longitudinally investigated the correlates of antiretroviral therapy (ART) adherence among perimenopausal and menopausal WLWH from Metro Vancouver. METHODS:Analyses drew on longitudinal data ... Read more >>

Menopause (Menopause (New York, N.Y.))
[2018, 25(5):531-537]

Cited: 6 times

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Leukocyte Telomere Length at Birth and During the Early Life of Children Exposed to but Uninfected With HIV After In Utero Exposure to Antiretrovirals.

Abhinav Ajaykumar, Hugo Soudeyns, Fatima Kakkar, Jason Brophy, Ari Bitnun, Ariane Alimenti, Arianne Y K Albert, Deborah M Money, Hélène C F Côté, , ,

Background:Maternal combination antiretroviral therapy (cART) during pregnancy could impact the health of human immunodeficiency virus (HIV)-exposed, HIV-uninfected (HEU) children, because some antiretrovirals cross the placenta and can inhibit telomerase. Our objective was to compare leukocyte telomere length (LTL) in HEU children and HIV-unexposed, HIV-uninfected (HUU) children at birth and in ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2018, 217(5):710-720]

Cited: 4 times

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No 354 - Lignes directrices canadiennes en matière de planification de la grossesse en présence du VIH.

Mona Loutfy, V Logan Kennedy, Vanessa Poliquin, Frederick Dzineku, Nicola L Dean, Shari Margolese, Alison Symington, Deborah M Money, Scot Hamilton, Tracey Conway, Sarah Khan, Mark H Yudin,

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2018, 40(1):115-137]

Cited: 0 times

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No. 354-Canadian HIV Pregnancy Planning Guidelines.

Mona Loutfy, V Logan Kennedy, Vanessa Poliquin, Frederick Dzineku, Nicola L Dean, Shari Margolese, Alison Symington, Deborah M Money, Scot Hamilton, Tracey Conway, Sarah Khan, Mark H Yudin,

OBJECTIVE:The objective of the Canadian HIV Pregnancy Planning Guidelines is to provide clinical information and recommendations for health care providers to assist Canadians affected by HIV with their fertility, preconception, and pregnancy planning decisions. These guidelines are evidence- and community-based and flexible and take into account diverse and intersecting local/population ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2018, 40(1):94-114]

Cited: 13 times

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No 208-Directive clinique sur la prise en charge du virus de l’herpès simplex pendant la grossesse.

Deborah M Money, Marc Steben,

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2017, 39(8):e192-e198]

Cited: 0 times

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The vaginal microbiome of pregnant women is less rich and diverse, with lower prevalence of Mollicutes, compared to non-pregnant women.

Aline C Freitas, Bonnie Chaban, Alan Bocking, Maria Rocco, Siwen Yang, Janet E Hill, Deborah M Money, ,

The vaginal microbiome plays an important role in maternal and neonatal health. Imbalances in this microbiota (dysbiosis) during pregnancy are associated with negative reproductive outcomes, such as pregnancy loss and preterm birth, but the underlying mechanisms remain poorly understood. Consequently a comprehensive understanding of the baseline microbiome in healthy pregnancy ... Read more >>

Sci Rep (Scientific reports)
[2017, 7(1):9212]

Cited: 44 times

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No. 208-Guidelines for the Management of Herpes Simplex Virus in Pregnancy.

Deborah M Money, Marc Steben,

<h4>Objective</h4>To provide recommendations for the management of genital herpes infection in women who want to get pregnant or are pregnant and for the management of genital herpes in pregnancy and strategies to prevent transmission to the infant.<h4>Outcomes</h4>More effective management of complications of genital herpes in pregnancy and prevention of transmission ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2017, 39(8):e199-e205]

Cited: 2 times

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No 211-Dépistage et prise en charge de la vaginose bactérienne pendant la grossesse.

Mark H Yudin, Deborah M Money,

<h4>Objectif</h4>Analyser les résultats et fournir des recommandations au sujet du dépistage et de la prise en charge de la vaginose bactérienne pendant la grossesse.<h4>Options</h4>Les options de pratique clinique prises en considération au moment de formuler la présente directive clinique.<h4>Issues</h4>Parmi les issues évaluées, on trouve les taux d'efficacité et de guérison ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2017, 39(8):e175-e183]

Cited: 0 times

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No. 211-Screening and Management of Bacterial Vaginosis in Pregnancy.

Mark H Yudin, Deborah M Money,

<h4>Objective</h4>To review the evidence and provide recommendations on screening for and management of bacterial vaginosis in pregnancy.<h4>Options</h4>The clinical practice options considered in formulating the guideline.<h4>Outcomes</h4>Outcomes evaluated include antibiotic treatment efficacy and cure rates, and the influence of the treatment of bacterial vaginosis on the rates of adverse pregnancy outcomes such ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2017, 39(8):e184-e191]

Cited: 2 times

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An Evaluation of Introduction of Rapid HIV Testing in a Perinatal Program.

Sarah Saunders, Karen Tulloch, Evelyn J Maan, Julianne van Schalkwyk, Deborah M Money,

<h4>Objective</h4>This study was conducted to evaluate the roll-out of rapid HIV testing as part of an emergency Prevention of Perinatal HIV Transmission Program. Specifically, HIV prevalence in this population, the reason(s) for performing the rapid HIV test, and compliance with recommendations for antiretroviral prophylaxis were assessed.<h4>Methods</h4>Since November 2011, all women ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2017, 39(8):668-675]

Cited: 0 times

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Self-collection based HPV testing for cervical cancer screening among women living with HIV in Uganda: a descriptive analysis of knowledge, intentions to screen and factors associated with HPV positivity.

Sheona M Mitchell, Heather N Pedersen, Evelyn Eng Stime, Musa Sekikubo, Erin Moses, David Mwesigwa, Christine Biryabarema, Jan Christilaw, Josaphat K Byamugisha, Deborah M Money, Gina S Ogilvie,

<h4>Background</h4>Women living with HIV (WHIV) are disproportionately impacted by cervical dysplasia and cancer. The burden is greatest in low-income countries where limited or no access to screening exists. The goal of this study was to describe knowledge and intentions of WHIV towards HPV self-collection for cervical cancer screening, and to ... Read more >>

BMC Womens Health (BMC women's health)
[2017, 17(1):4]

Cited: 6 times

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Mobile Text Messaging to Improve Medication Adherence and Viral Load in a Vulnerable Canadian Population Living With Human Immunodeficiency Virus: A Repeated Measures Study.

Elizabeth King, Karen Kinvig, Jonathan Steif, Annie Q Qiu, Evelyn J Maan, Arianne Yk Albert, Neora Pick, Ariane Alimenti, Mary H Kestler, Deborah M Money, Richard T Lester, Melanie Caroline Margaret Murray,

<h4>Background</h4>Combination antiretroviral therapy (cART) as treatment for human immunodeficiency virus (HIV) infection is effective and available, but poor medication adherence limits benefits, particularly in vulnerable populations. In a Kenyan randomized controlled trial, a weekly text-messaging intervention (WelTel) improved cART adherence and HIV viral load (VL). Despite growing evidence for short ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2017, 19(6):e190]

Cited: 11 times

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