Full Text Journal Articles by
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Corrigendum: Ivabradine Treatment Reduces Cardiomyocyte Apoptosis in a Murine Model of Chronic Viral Myocarditis.

Ge Li-Sha, Liu Li, Zhou De-Pu, Shi Zhe-Wei, Gu Xiaohong, Chen Guang-Yi, Li Jia, Lin Jia-Feng, Chu Maoping, Li Yue-Chun,

[This corrects the article DOI: 10.3389/fphar.2018.00182.]. ... Read more >>

Front Pharmacol (Frontiers in Pharmacology)
[2019, 10:1126]

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Ivabradine Treatment Reduces Cardiomyocyte Apoptosis in a Murine Model of Chronic Viral Myocarditis.

Ge Li-Sha, Liu Li, Zhou De-Pu, Shi Zhe-Wei, Gu Xiaohong, Chen Guang-Yi, Li Jia, Lin Jia-Feng, Chu Maoping, Li Yue-Chun,

This study was designed to explore the effects of ivabradine on cardiomyocyte apoptosis in a murine model of chronic viral myocarditis (CVMC). Mice were inoculated intraperitoneally with Coxsackievirus B3 at days 1, 14, and 28, respectively. On day 42, the mice were gavaged with ivabradine for 30 days until the ... Read more >>

Front Pharmacol (Frontiers in Pharmacology)
[2018, 9:182]

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The cholinergic anti-inflammatory pathway ameliorates acute viral myocarditis in mice by regulating CD4+ T cell differentiation.

Zhou De-Pu, Ge Li-Sha, Chen Guang-Yi, Gu Xiaohong, Xing Chao, Zheng Cheng, Zhang Wen-Wu, Li Jia, Lin Jia-Feng, Chu Maoping, Li Yue-Chun,

Many studies have found that abnormalities in the proportion and differentiation of CD4+ T cells (Th cells) are closely related to the pathogenesis of viral myocarditis (VMC). Our previous research indicates that the cholinergic anti-inflammatory pathway (CAP) attenuates the inflammatory response of VMC and downregulates the expression of cytokines in ... Read more >>

Virulence (Virulence)
[2018, 9(1):1364-1376]

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Approach selection of radiofrequency catheter ablation for ventricular arrhythmias originating from the left ventricular summit: potential relevance of Pseudo Delta wave, Intrinsicoid deflection time, maximal deflection index.

Cheng Zheng, Jin Li, Jia Li, De-Pu Zhou, Xiao-Wei Li, Shu-Jie Wu, Jia-Feng Lin,

Ventricular arrhythmias (VAs) originating from the left ventricular summit is a challenge for radiofrequency catheter ablation (RFCA). The present study aimed to investigate the appropriate RFCA strategy for VAs originating from the left ventricular summit.Forty-five consecutive patients with VAs arising from the left ventricular summit were successfully ablated at our ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2017, 17(1):140]

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Origins location of the outflow tract ventricular arrhythmias exhibiting qrS pattern or QS pattern with a notch on the descending limb in lead V1.

Cong Lin, Cheng Zheng, De-Pu Zhou, Xiao-Wei Li, Shu-Jie Wu, Jia-Feng Lin,

Ventricular outflow tract(VOT) ventricular arrhythmias(VAs) presenting qrS pattern or QS pattern with a notch on the descending limb in lead V1 were consistently thought of arising from the commissure between left and right coronary cusp (L-RCC) by previous studies. However, we found they could originate from other anatomic structures in ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2017, 17(1):124]

Cited: 1 time

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Clinical and electrocardiographic characteristics of infarctional ventricular ectopic beats: An observational study.

Yuechun Li, Shi Zhe-Wei, Zheng Cheng, Chen Guang-Yi, Zhou De-Pu, Li Xiao-Wei, Guan Xueqiang, Lin Jiafeng, Chen Peng,

The purpose of this study was to explore the clinical and electrocardiographic characteristics of infarctional ventricular ectopic beats (IVEBs).Thirty-eight acute myocardial infarction (AMI) patients with IVEB and 109 AMI patients without IVEB were analyzed. The morphological changes of QRS complex, ST segment, and T wave were compared to IVEB with ... Read more >>

Medicine (Baltimore) (Medicine)
[2017, 96(21):e7007]

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Right Cervical Vagotomy Aggravates Viral Myocarditis in Mice Via the Cholinergic Anti-inflammatory Pathway.

Ge Li-Sha, Chen Xing-Xing, Wu Lian-Pin, Zhou De-Pu, Li Xiao-Wei, Lin Jia-Feng, Li Yue-Chun,

The autonomic nervous system dysfunction with increased sympathetic activity and withdrawal of vagal activity may play an important role in the pathogenesis of viral myocarditis. The vagus nerve can modulate the immune response and control inflammation through a 'cholinergic anti-inflammatory pathway' dependent on the α7-nicotinic acetylcholine receptor (α7nAChR). Although the ... Read more >>

Front Pharmacol (Frontiers in Pharmacology)
[2017, 8:25]

Cited: 9 times

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Erratum: Dose-dependent protective effect of nicotine in a murine model of viral myocarditis induced by coxsackievirus B3.

Ge Li-Sha, Zhao Jing-Lin, Chen Guang-Yi, Liu Li, Zhou De-Pu, Li Yue-Chun,

Sci Rep (Scientific reports)
[2015, 5:17247]

Cited: 1 time

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Dose-dependent protective effect of nicotine in a murine model of viral myocarditis induced by coxsackievirus B3.

Ge Li-Sha, Zhao Jing-Lin, Chen Guang-Yi, Liu Li, Zhou De-Pu, Li Yue-Chun,

The alpha 7 nicotinic acetylcholine receptor (alpha7 nAChR) was recently described as an anti-inflammatory target in various inflammatory diseases. The aim of this study was to investigate the dose-related effects of nicotine, an alpha7 nAChR agonist, in murine model of viral myocarditis. BALB/C mice were infected by an intraperitoneally injection ... Read more >>

Sci Rep (Scientific reports)
[2015, 5:15895]

Cited: 8 times

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